Clinical use of fetal measurements to determine the whelping day in German shepherd breed bitches.

The aim of this work was to use a linear regression model previously developed in a pilot study to calculate days before parturition (DbP) using inner chorionic cavity (ICC), biparietal diameter (BPD), crown-rump length (CRL), body diameter (BD) and deep portion of telencephalic vesicle (DPTV) in German shepherd dogs (GSD) with known ovulation day and then to test that model in bitches with unknown ovulation day. In our current study, a model for GSD bitches published in a previous report, proved satisfactory for ICC [DbP=44.76-(4.34×ICC)] and BPD [DbP=38.65-(12.86×BPD)]. We therefore used their model, but developed a new one for CRL, BD and DPTV. For ICC and BPD, we tested accuracy for more than 35days before parturition (ICC) and more than 15days before parturition (BPD). Measurements were taken on at least two fetuses during each ultrasound recording (US) of 22 GSD bitches with known (n=16) and unknown (n=6) ovulation days. The accuracy of the above model was 77-100% for ICC and 83-96% for BPD with a precision of ±1 and ±2days, respectively. Accuracy increased significantly when US was performed more than 35days before parturition for ICC and more than 15days before parturition for BPD. BD and CRL were the most accurate parameters (R2=0.95 and 0.85). In bitches with unknown ovulation day, BD accuracy was 71.4-100% with a precision of ±1day and ±2days, respectively. CRL and DPTV were less accurate (±1day, 60%; ±2days, 80% accuracy).

Postponement of puberty in queens treated with deslorelin.

Objectives The purpose of this study was to assess efficacy of deslorelin, a gonadotropin-releasing hormone (GnRH) agonist marketed in Europe for the control of male dog reproduction, for the postponement of puberty in queens. Methods Nine prepubertal queens aged 3-9 months were selected for this study; their general and reproductive health was checked through clinical, haematological, vaginal cytology and hormonal tests. Following treatment with a 4.7 mg deslorelin implant, each cat received a monthly clinical examination and blood was collected for hormonal assay every third month. Cats were monitored for 14.1 ± 5.2 (range 7-23) months. Results All cats were in good body condition and normal health prior to treatment. Their health status remained unchanged throughout the study and no significant variation was observed with regard to serum progesterone or oestradiol. Seven days post-treatment, 1/9 queens showed signs of heat, and one other queen showed complete vaginal keratinisation. No other signs of heat were subsequently observed in any other queen. Five queens were lost during the study after 7, 7, 16, 17 and 18 months of observation (during which time they did not show signs of heat). By the end of the study, no sign of puberty was observed in the four remaining queens at 21-36 months of age. Conclusions and relevance A 4.7 mg deslorelin implant was able to suppress the feline pituitary-gonadal axis, leading to postponement of puberty for up to 21-36 months in the four queens that completed the study. Deslorelin can be considered as a safe method to postpone puberty in queens.