Trends of measles in Tanzania: A 5-year review of case-based surveillance data, 2018-2022.

OBJECTIVES: Tanzania observed a gradual increase in the number of measles cases since 2019 with a large outbreak recorded during 2022. This study describes the trend of measles in Tanzania over a 5-year period from 2018-2022. METHODS: This was a descriptive study conducted using routine measles case-based surveillance system including 195 councils of the United Republic of Tanzania. RESULTS: Between 2018 and 2022 there were 12,253 measles cases reported. Out of 10,691 (87.25%) samples tested by enzyme-linked immunosorbent assay, 903 (8.4%) were measles immunoglobulin M positive. The highest number of laboratory-confirmed measles cases was in 2022 (64.8%), followed by 2020 (13.8%), and 2019 (13.5%). Out of 1279 unvaccinated cases, 213 (16.7%) were laboratory-confirmed measles cases compared to 77/723 (10.6%) who were partially vaccinated and 71/1121 (6.3%) who were fully vaccinated (P < 0.001). Children aged between 1-4 years constituted the most confirmed measles cases after laboratory testing, followed by those aged 5-9 years. There was a notable increase in the number of laboratory-confirmed measles cases in children <1 year and 10-14 years during 2022 compared to previous years. The vaccination coverage of the first dose of measles-containing vaccine (MCV1) was maintained >90% since 2013 while MCV2 increased gradually reaching 88% in 2022. CONCLUSIONS: Accumulation of susceptible children to measles due to suboptimal measles vaccination coverage over the years has resulted in an increase in the number of laboratory-confirmed measles cases in Tanzania with more cases recorded during the COVID-19 pandemic. Strengthening surveillance, routine immunization, and targeted strategies are key to achieving the immunity levels required to interrupt measles outbreaks.

Novel methodology for measuring intraoral wear in enamel and dental restorative materials.

OBJECTIVES: To test the hypotheses that (a) the chairside/handheld dental scanner combined with a metrology software will measure clinical wear in vivo in agreement with measurements from X-ray computed microtomography and; (b) polished monolithic zirconia does not cause accelerated wear of opposing enamel. MATERIALS AND METHODS: Thirty single crowns were randomized to receive a monolithic zirconia or metal-ceramic crown. Two non-restored opposing teeth in the same quadrants were identified to serve as enamel controls. After cementation, quadrants were scanned using an intraoral dental scanner. Patients were recalled at 6-months and 1-year for re-scanning. Scanned images were compared using a metrology software to determine maximum vertical wear of teeth. The accuracy of the scanning measurements from this new method was compared with X-ray computed microtomography (micro-CT) measurements. Statistical analysis was performed using Mann-Whitney U test to determine significant differences between wear of enamel against zirconia, metal-ceramic or enamel. Linear regression analysis determined agreement between measurements obtained using intraoral scanning and micro-CT. RESULTS: Regression analysis demonstrated that there is a quantitative agreement between depth and volume measurements produced using intraoral scanning and the micro-CT methodologies. There was no significant difference between the wear of enamel against polished monolithic zirconia crowns and enamel against enamel. CONCLUSIONS: Intraoral scanning combined with a matching software can accurately quantify clinical wear to verify that monolithic zirconia exhibited comparable wear of enamel compared with metal-ceramic crowns and control enamel. Agreement between the intraoral scanner and the micro-CT was 99.8%. Clinical Trials.gov NCT02289781.

Bone stability around implants in elderly patients with reduced bone mineral density - a prospective study on mandibular overdentures.

OBJECTIVE: The purpose of this prospective clinical study was to determine whether reduced bone mineral density (BMD) is correlated with a higher risk for dental implant therapy in an elderly patient population. MATERIAL AND METHODS: Seventy-nine patients recruited at the Prince Philip Dental Hospital were provided with 2-implant-supported mandibular overdentures. Skeletal BMD was recorded before the implant therapy. The World Health Organization Osteoporosis Diagnosis Classification (femoral neck score) was utilized to define the osteoporosis status of patients. Periapical radiographs were taken with a special radiographic holder at the time of implant loading (baseline) and at follow-up examinations. The mesial and distal marginal bone levels of each implant were measured. The mean marginal bone loss (mMBL) and greatest marginal bone loss (GBL) of four implant sites at patient level were recorded for data analysis. Clinical examination including plaque score (PI) and bleeding on probing (BOP) was recorded. RESULTS: Of the 79 patients recruited in the study, the survival rate of implant was 98.7%. Sixty-three patients (79.7%) were finally available for data collection and statistical analyses. The mean follow-up time was 62.9 (SD = 15.2) months with the mean MBL 0.65 mm (SD = 0.67) and mean GBL 1.25 mm (SD = 0.83), respectively. The average BOP and PI of patients were 49.6% (SD = 30.8) and 47.4% (SD = 37.4). Only BOP was found significantly correlated with mMBL (r = 0.321, P = 0.01). Skeletal BMD was not associated with marginal bone loss (mean MBL: r = -0.094, P = 0.466; mean GBL: r = 0.04, P = 0.761). CONCLUSIONS: Within the limits of this study, osteoporosis was not a contraindication for implant therapy, and reduced skeletal BMD was not associated with increased marginal bone loss around implants or other complications in an elderly population.

Examining Asphaltene Solubility on Deposition in Model Porous Media.

Asphaltenes are known to cause severe flow assurance problems in the near-wellbore region of oil reservoirs. Understanding the mechanism of asphaltene deposition in porous media is of great significance for the development of accurate numerical simulators and effective chemical remediation treatments. Here, we present a study of the dynamics of asphaltene deposition in porous media using microfluidic devices. A model oil containing 5 wt % dissolved asphaltenes was mixed with n-heptane, a known asphaltene precipitant, and flowed through a representative porous media microfluidic chip. Asphaltene deposition was recorded and analyzed as a function of solubility, which was directly correlated to particle size and Péclet number. In particular, pore-scale visualization and velocity profiles, as well as three stages of deposition, were identified and examined to determine the important convection-diffusion effects on deposition.

In vitro ultrasonographic measurement of jawbone to predict bone quality.

PURPOSE: The purpose of this in vitro study was to determine whether there is a correlation between the speed of sound (SOS), as measured by quantitative ultrasound (QUS), and bone quality, as expressed in Hounsfield units (HU) measured by spiral computed tomography in the mandible. MATERIALS AND METHODS: Dry human mandibles (n = 23) with 69 regions of interest (ROIs) were selected for QUS and computed tomographic measurements of SOS and HU, respectively. The three ROIs defined in each mandible were the right canine, left canine, and central incisor regions. A time-of-flight approach was used to establish the SOS through bone. The mean HU value derived from scanned computed tomographic images of each ROI was evaluated for correlation with SOS. RESULTS: The Spearman rho test revealed a modest but significant correlation between SOS and HU (R2 quadratic = 0.339, P < .01). CONCLUSION: In this in vitro study conducted in dry human mandibles, a statistically significant correlation was identified between QUS and HU.

Diagnostic performance of mandibular bone density measurements in assessing osteoporotic status.

PURPOSE: The study evaluated the diagnostic performance of computed tomography (CT) bone density measurements (in Hounsfield units [HU]) in assessing the osteoporotic status of edentulous subjects (21 men, 40 women) scheduled to receive mandibular implant-supported overdentures. MATERIALS AND METHODS: Density (in HU) of 61 left and 61 right mandibular canine sites was measured. Each subject was also subject to body bone mineral density measurements (dual-energy x-ray absorptiometry). Bone density T-score values of total hip, femoral neck, spine (L1 to L4), and total body were assessed. Pearson correlations were conducted between HU of each mandibular bone site and the subject's T-score values. Sensitivity/specificity and receiver operating characteristic curve analyses were used to assess the diagnostic performance of HU in detecting subjects who were, based on each of the four T-scores: (1) "not osteonormal", ie, with a T-score at or below -1.0; or (2) osteoporotic, ie, with a T-score at or below -2.5. RESULTS: HU measurements of mandibular bone sites were found to have modest but significant correlations with each bone density T-score value (total hip, femoral neck, spine, total body). CT mandibular site HU measurement has diagnostic value in detecting a "not osteonormal" condition when total hip, spine, or total body T-scores were used, but not when femoral neck T-score was used. CONCLUSIONS: Based on the limited sample size, optimal HU cutoff values of ~530, ~600, and ~640 HU for total hip, spine, or total body T-scores, respectively, were proposed. CT mandibular site HU measurement had diagnostic value in detecting osteoporosis when spine T-score was used but not when total hip, femoral neck, and total body T-scores were used. An optimal HU cutoff value of ~460 HU for spine T-score was proposed.

Prosthetic outcome, patient complaints, and nutritional effects on elderly patients with magnet-retained, implant-supported overdentures--a 1-year report.

PURPOSE: To study the changes in treatment outcomes of complete dentures and magnet-retained, implant-supported overdentures in a group of elderly patients. MATERIALS AND METHODS: In this nonrandomized trial, 43 edentulous patients (14 men and 29 women) were fitted with complete dentures followed by implant-supported mandibular overdenture in a sequential model. Treatment outcomes used for analysis included objective assessment of denture quality (Woelfel's index), patient satisfaction, nutritional status, body mass index (BMI), and serum albumin level. The McNemar test was used to determine if significant differences in the Woelfel's index and nutritional status existed at different treatment phases. Repeated measures ANOVA and multiple pairwise comparison tests were used to analyze patient satisfaction. BMI status and serum albumin level at different treatment phases were analyzed with one-way ANOVA and Tukey post hoc test. RESULTS: At the 1-year follow-up, significant improvements were recorded for the objective assessment of denture quality and patient complaints (P < .05). No subject was found to be malnourished at pretreatment and in subsequent treatment phases. BMI and serum albumin level were not significantly different at different treatment phases (P > .05) CONCLUSIONS: The present study demonstrated that in elderly patients with stable health and nutritional status, complete dentures made in a university clinic brought about overall improvement in denture quality and reduction in denture complaint score. Insertion of mandibular implant-supported overdentures further improved the mandibular denture quality and reduced the mandibular denture complaint score. In this group of patients, no improvement in BMI, serum albumin value, and nutritional status were documented.

Correlation between dental implant insertion torque and mandibular alveolar bone density in osteopenic and osteoporotic subjects.

PURPOSE: Osteoporotic patients require particular attention during implant placement, and insertion torque (IT) has been established as a simple and noninvasive method to assess local bone quality and primary implant stability. This study aimed to test the hypothesis that IT was not significantly correlated with bone density, as assessed with computed tomography, in a group of osteopenic and osteoporotic patients. In addition, the hypothesis that IT was not significantly correlated with implant length was tested. MATERIALS AND METHODS: Fifty-three completely edentulous patients with compromised bone mineral density (osteoporotic or osteopenic) who required treatment with complete maxillary dentures and complete mandibular implantsupported overdentures participated in the study. Each patient received two screw-shaped self-tapping implants (Branemark Mark III TiUnite) at the mandibular canine regions. The IT of each implant during placement was recorded. The Pearson correlation between IT and implant site bone density (Hounsfield unit) obtained from presurgical computed tomographic scans was analyzed. The relationship between IT and implant length was also studied. RESULTS: IT was significantly correlated to implant site bone density but not to implant length. CONCLUSION: IT can be a viable and practical means to assess mandibular bone quality in patients with compromised general bone density.

Effect of surface treatment on shear bond strength of zirconia to human dentin.

PURPOSE: The effect of surface treatment using tribochemical silica coating/silane coupling on the shear bond strengths of (1) a glass-infiltrated, zirconia-reinforced alumina (In-Ceram Zirconia) and (2) a yttria-stabilized zirconia ceramic (YZ Zirconia) to human dentin was studied. MATERIALS AND METHODS: Twelve specimens of each ceramic were randomly assigned to one of three surface treatments: (1) no surface treatment (control group); (2) a chairside tribochemical silica coating/silane coupling system (CoJet group); and (3) a laboratory tribochemical silica coating/silane coupling system (Rocatac group). The mode of failure of each specimen was determined under magnification. RESULTS: The shear bond strengths (mean ± SD) of In-Ceram Zirconia of the control, CoJet and Rocatec groups were 5.7 ± 4.3 MPa, 11.4 ± 5.4 MPa, and 6.5 ± 4.8 MPa, respectively. The corresponding figures for YZ Zirconia were 8.2 ± 5.4 MPa, 9.8 ± 5.4 MPa, and 7.8 ± 4.7 MPa. Two-way ANOVA revealed significant differences in bond strength due to the difference in surface treatment (p= 0.02), but the bond strengths between the two ceramics were not significantly different (p= 0.56). Post hoc tests showed that In-Ceram Zirconia treated with CoJet had significantly higher shear bond strengths than those untreated (p < 0.05) or treated with Rocatec (p < 0.05). Surface treatment did not affect the shear bond strength of YZ Zirconia significantly (p > 0.05). CONCLUSION: The bonding of In-Ceram Zirconia can be improved by the chairside surface treatment system.

Thermal mixing of two miscible fluids in a T-shaped microchannel.

In this paper, thermal mixing characteristics of two miscible fluids in a T-shaped microchannel are investigated theoretically, experimentally, and numerically. Thermal mixing processes in a T-shaped microchannel are divided into two zones, consisting of a T-junction and a mixing channel. An analytical two-dimensional model was first built to describe the heat transfer processes in the mixing channel. In the experiments, de-ionized water was employed as the working fluid. Laser induced fluorescence method was used to measure the fluid temperature field in the microchannel. Different combinations of flow rate ratios were studied to investigate the thermal mixing characteristics in the microchannel. At the T-junction, thermal diffusion is found to be dominant in this area due to the striation in the temperature contours. In the mixing channel, heat transfer processes are found to be controlled by thermal diffusion and convection. Measured temperature profiles at the T-junction and mixing channel are compared with analytical model and numerical simulation, respectively.

Probability of failure of machined zirconia dental ceramic core materials.

The purpose of this study was to compare the probability of failure, expressed as B10 strength, of three systems of machined zirconia ceramics (Lava, DC-Zirkon, and Cercon) with a zirconia-reinforced aluminum ceramic (In-Ceram Zirconia). Ten rectangular specimens of each material were subjected to a three-point flexural strength test. The B10 strength of Lava was significantly lower than that of DC-Zirkon but significantly higher than that of Cercon and In-Ceram Zirconia. The B10 strength of Cercon and In-Ceram Zirconia were not significantly different from one another. The machined zirconia ceramics appeared to fail primarily with intergranular fracture.

Shear bond strength between nickel-chromium and human dentine using a dual-cure, self-adhesive universal resin luting agent.

The adhesive property of a dual-cure, self-adhesive universal resin luting agent (Rely X Unicem, 3M ESPE) between nickel-chromium (Ni-Cr) and human dentine was compared with three conventional resin luting agents (Calibra, Dentsply; Panavia-F, Kuraray; All-bond 2 C & B cement, Bisco). Ten Ni-Cr rods were bonded to human dentine with each of the four luting agents, and were subjected to shear bond test. Results showed that there was no significant difference in shear bond strengths among the luting agents. A dual-cure, self-adhesive universal resin luting agent was shown to have comparable adhesive property between Ni-Cr and human dentine as three other conventional resin luting agents. Given the simplicity of use of the dual-cure, self-adhesive universal resin luting agent, it appears to be promising in clinical applications.

Chemical solubility and flexural strength of zirconia-based ceramics.

PURPOSE: This study was undertaken to investigate the chemical solubility and flexural strengths of 3 zirconia-based dental ceramics: In-Ceram Zirconia (IZ), In-Ceram 2000 YZ CUBES (YZ Zirconia) (Vita Zahnfabrik), and Cercon (Dentsply). A pressable lithium disilicate-reinforced glass ceramic (IPS Empress 2, Ivoclar Vivadent) was used as a control. MATERIALS AND METHODS: Ten block specimens (12 x 6 x 4 mm) of each ceramic material were prepared for chemical solubility testing. Each specimen was refluxed in 4% acetic acid solution for 16 hours. The percentage loss of mass and the loss of mass per unit of surface area for each specimen were calculated. Ten bar-shaped (21 x 5 x 2 mm) and 10 disk-shaped (16 mm diameter, 1.2 mm thickness) specimens of each ceramic material were prepared and tested for uniaxial flexural strength (UFS) and biaxial flexural strength (BFS). X-ray diffraction analyses were conducted to determine the relative amount of the monoclinic phase of the as-sintered and fractured surfaces of the zirconia ceramics. RESULTS: There were no significant differences among the ceramics in chemical solubility by percentage mass or mass/surface area. For UFS, YZ Zirconia (899 +/- 109 MPa) > Cercon (458 +/- 95 MPa) IZ (409 +/- 60 MPa) > Empress 2 (252 +/- 36 MPa). For BFS, YZ Zirconia (1,107 +/- 116 MPa) > Cercon (927 +/- 146 MPa) > IZ (523 +/- 51 MPa) > Empress 2 (359 +/- 43 MPa). The fractured YZ Zirconia surface contained approximately 5 times as much monoclinic phase compared to that of its intact surface. The fractured IZ and Cercon surfaces contained approximately twice as much monoclinic phase compared to those of intact surfaces. CONCLUSION: The ceramics tested all satisfied the chemical solubility allowance required of core ceramic material (type I, Class 1 or type II, Class 1) according to the International Organization for Standardization 6872:1995(E) specifications on dental ceramic. The zirconia-based ceramics possessed significantly higher flexural strengths than the control lithium disilicate ceramic. Their clinical application appears sufficiently promising for long-term clinical studies to be undertaken.

Contrast ratios and masking ability of three types of ceramic veneers.

STATEMENT OF PROBLEM: Although ceramic veneers have been proven to be clinically successful in longevity studies, there is little information on the contrast ratios and masking ability of the available ceramic systems because dental laboratory technology and expensive experimental equipment are required for the investigation. Moreover, the complexity in understanding how to evaluate translucent ceramic materials may also explain why information in this area is limited. PURPOSE: The purpose of this study was to determine the contrast ratios and masking abilities of 3 types of all-ceramic veneers by measuring their luminance and color difference over white and black backgrounds. MATERIAL AND METHODS: Disk-shaped specimens (8-mm diameter x 0.7-mm thickness) of Shade A2 (Vita Lumin) of 3 types of all-ceramic systems: Procera (n=8), Empress 2 (n=8), and Vitadur Alpha (n=10) were fabricated. The luminance (as Y) and color (as CIE L*a*b*) of the specimens were measured with a colorimeter. The contrast ratio (CR=Yb/Yw), defined as the ratio of illuminance (Y) of the test material when it is placed on the black background (Yb) to the illuminance of the same material when it is placed over a white background (Yw), was determined. The masking ability of a specimen was evaluated by calculating the color difference (DeltaE) of the veneers over white and black backgrounds. Both CR and DeltaE* data were analyzed with 1-way ANOVA and the Tukey HSD test (alpha=.05). RESULTS: The mean contrast ratios (SD) of Procera, Empress 2, and Vitadur Alpha specimens were 0.50 (0.02), 0.46 (0.05), and 0.39 (0.02), respectively. CR values were significantly different among the 3 materials (P<.001). Procera veneers had a significantly higher CR compared to Empress 2 (P=.01) or Vitadur Alpha (P=.01), whereas the CR of Empress 2 was significantly higher than that of Vitadur Alpha (P=.046). Color difference (DeltaE*) (SD) of Procera, Empress 2, and Vitadur Alpha specimens over black and white backgrounds were 24.46 (1.03), 25.80 (1.03), and 31.08 (1.19), respectively. DeltaE* values were statistically different among the 3 materials (P<.001). Vitadur Alpha specimens had significantly higher DeltaE* when compared with Procera (P<.001) or Empress 2 (P<.001), whereas DeltaE* values between Procera and Empress 2 were not significantly different (P=.331). CONCLUSIONS: Vitadur Alpha had significantly lower contrast ratio and poorer masking ability compared to Procera or Empress 2. The clinical application of Vitadur Alpha as a veneer material over discolored teeth is cautioned. Although the contrast ratio of Procera was significantly higher than that of Empress 2, the masking abilities of these materials were not significantly different. The clinical application of these 2 ceramics as a veneer material may still be limited when applied over intense tooth discoloration because neither can fully mask the color of a black background.

Comparison of the retentive characteristics of cobalt-chromium and commercially pure titanium clasps using a novel method.

This study aimed to compare the retentive forces of cast cobalt-chromium (Co-Cr) and commercially pure titanium (cpTi) clasps. A clasp assembly comprising a pair of symmetrical clasps was made to fit the opposite halves of a hardened stainless-steel sphere. This twin clasp was designed to counterbalance the tipping forces when the clasp assembly was drawn from the sphere. A total of 120 clasp assemblies were fabricated in cast Co-Cr and cpTi and placed at undercut depths of 0.25 mm, 0.50 mm, and 0.75 mm (n = 20 for each). For Co-Cr clasps, the retentive forces at these undercuts depths were 2.34 +/- 0.23 N, 4.65 +/- 0.35 N, and 7.56 +/- 0.50 N, respectively. The corresponding retentive forces for cpTi clasps were 1.24 +/- 0.13 N, 2.34 +/- 0.23 N, and 3.70 +/- 0.27 N. The retentive force of cpTi clasps was approximately half that of Co-Cr clasps for the same undercut depth.

Influence of dental status on nutritional status of geriatric patients in a convalescent and rehabilitation hospital.

PURPOSE: To investigate 6 dental statuses as risk factors for malnutrition in geriatric patients admitted to a convalescent and rehabilitation hospital. MATERIALS AND METHODS: One hundred twenty (59 men and 61 women) geriatric patients admitted to a convalescent and rehabilitation hospital were recruited. Three biochemical and hematologic parameters (albumin, hemoglobin, and lymphocyte count) were used for analysis. Malnutrition was defined as Body Mass Index (BMI) below 18.5 and albumin level under 35 g/L. The number of natural or prosthetic teeth in the dentate patients, and the presence of one or both dentures in the edentate patients, were recorded. Risk factors associated with malnutrition were investigated, namely: (1) edentulism among all patients, (2) edentulism without a set of complete dentures among all patients, (3) edentulism without a set of complete dentures among the edentate patients, (4) decreased number (< 6) of occluding pairs of natural or prosthetic teeth among the dentate patients, (5) decreased number (< 5) of posterior occluding pairs of natural or prosthetic teeth among the dentate patients, and (6) absence of posterior occluding pairs of natural or prosthetic teeth among the dentate patients. One-way ANOVA and Bonferroni multiple comparisons were used to determine if significant differences in the anthropometric, biochemical, and hematologic parameters existed between the patients with different dental statuses. The odds ratio and significance of 6 dental statuses as risk factors of malnutrition were calculated (P = .05). RESULTS: BMI, albumin, and hemoglobin levels of the malnourished patients were significantly lower than those of nourished patients (P < .05). Lymphocyte count was not significantly different between the 2 patient groups (P > .05). The status of edentate patients without a set of complete dentures compared with other edentate and dentate patients was the only independent risk factor (P < .05) in the 6 statuses studied. CONCLUSION: Primary healthcare workers caring for hospitalized geriatric patients should identify edentate patients without a set of complete dentures for the possibility of malnutrition.

Effect of water storage on the impact strength of three glass fiber-reinforced composites.

OBJECTIVES: The effect of water sorption on the impact strengths of two pre-impregnated fiber-reinforced composites (FRCs) and one impregnated FRC were studied. All FRCs were available clinically. METHODS: Eight 1.0 mm x 2.0 mm x 25.0mm bar-shaped specimens of each material were prepared according to manufacturers' instructions. The impact strength of each specimen was tested (adoption from ISO 179-1 Plastics-Determination of Charpy impact properties) after the specimens were immersed in 23.0+/-1 degrees C distilled water for seven, 60 and 180 days. The data were analyzed using the Weibull method. Scanning electron micrographs were taken to examine the mode of failure. RESULTS: Weibull analysis of the B10 strength of the FRCs showed that the difference in impact strength for each FRC due to the duration of water immersion was not significant (P>0.05). The impact strength of pre-impregnated E-glass FRC (Vectris) (75 kJ/m(2)) was not significantly different from the pre-impregnated S-glass FRC (FiberKor) (66 kJ/m(2)) (P>0.05). The impregnated FRC possessed impact strength (42 kJ/m(2)) that was not significantly different from the pre-impregnated S-glass FRC but was significantly lower than the pre-impregnated E-glass FRC. x100 SEMs of the three types of FRC specimens revealed fiber failure to be the predominant mode of failure. SIGNIFICANCE: Water immersion up to 180 days duration did not significantly affect the impact strength of three FRCs. The impact strength of the impregnated FRC was not significantly different from the pre-impregnated S-glass FRC but was significantly lower than the pre-impregnated E-glass FRC.

Assessment of Joule heating and its effects on electroosmotic flow and electrophoretic transport of solutes in microfluidic channels.

Joule heating is inevitable when an electric field is applied across a conducting medium. It would impose limitations on the performance of electrokinetic microfluidic devices. This article presents a 3-D mathematical model for Joule heating and its effects on the EOF and electrophoretic transport of solutes in microfluidic channels. The governing equations were numerically solved using the finite-volume method. Experiments were carried out to investigate the Joule heating associated phenomena and to verify the numerical models. A rhodamine B-based thermometry technique was employed to measure the solution temperature distributions in microfluidic channels. The microparticle image velocimetry technique was used to measure the velocity profiles of EOF under the influence of Joule heating. The numerical solutions were compared with experimental results, and reasonable agreement was found. It is found that with the presence of Joule heating, the EOF velocity deviates from its normal "plug-like" profile. The numerical simulations show that Joule heating not only accelerates the sample transport but also distorts the shape of the sample band.

Effect of original water content in acrylic resin on processing shrinkage.

PURPOSE: The aim of this study was to determine the original water content of a supplied acrylic resin powder and a monomer and of dry heat-processed acrylic bars. The effect of the original water content of acrylic resin on processing shrinkage was also investigated. MATERIALS AND METHODS: Ten bar specimens were fabricated using dried and as-supplied (control) acrylic resins. The resins were polymerized and cooled, then weighed and measured to determine the amount of shrinkage. The initial water content of the specimens was determined by thorough drying, and results were compared with the Student ttest. RESULTS: The initial water content and processing shrinkage of the dried acrylic resin bars were both significantly lower (P < .0001) than those of the as-supplied acrylic resin bars. CONCLUSION: The processing shrinkage of acrylic resin made from dried constituents was significantly less than that of resin made from products as supplied by the manufacturer. However, it is not known if this change is of clinical significance.

Effect of water storage on the flexural properties of three glass fiber-reinforced composites.

PURPOSE: The effect of water sorption on the flexural strength and flexural modulus of three fiber-reinforced composites was studied. MATERIALS AND METHODS: Bar-shaped specimens of each material were prepared according to the manufacturers' instructions. The flexural strength and modulus of each specimen were tested after the specimens were immersed in distilled water for 1, 7, 60, and 180 days. SEMs were taken to examine the mode of failure. The volume percentage of fiber content of each fiber-reinforced composite was experimentally estimated. RESULTS: The ascending order of flexural strength and modulus among the materials was generally: FibreKor < Stick < Vectris. The flexural strengths of Stick and FibreKor specimens at 1 and 180 days were not significantly different. Although the 180-day Vectris specimens possessed significantly lower flexural strength than the 1-day specimens, the flexural strengths of Vectris specimens at 1, 7, 60, and 180 days remained significantly higher than those of Stick and FibreKor. The difference in flexural modulus for each fiber-reinforced composite related to the duration of water immersion was not significant. CONCLUSION: Water immersion affected the flexural strengths of the three composites to a different degree but did not affect their flexural moduli significantly. For each duration of water immersion, the flexural property of the fiber-reinforced composite, in ascending order of significant difference, was: FibreKor < Stick < Vectris.