1.
J Biol Chem
; 283(48): 33276-86, 2008 Nov 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18832379
RESUMO
The B chain of ricin was expressed and delivered to the endoplasmic reticulum of tobacco protoplasts where it disappeared with time in a manner consistent with degradation. This turnover did not occur in the vacuoles or upon secretion. Indeed, several lines of evidence indicate that, in contrast to the turnover of endoplasmic reticulum-targeted ricin A chain in the cytosol, the bulk of expressed ricin B chain was degraded in the secretory pathway.