1.
Experientia
; 40(12): 1426-7, 1984 Dec 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-6391951
RESUMO
Incubation of rat islets with phenylalanine increased the tissue content of phosophoenolpyruvate, both in the presence and in the absence of glucose. At the same time, L-phenylalanine neither stimulated nor inhibited insulin release. It is unlikely that insulin secretion is tightly coupled to the availability of phosphoenolpyruvate in rat islets.
Assuntos
Insulina/metabolismo , Ilhotas Pancreáticas/metabolismo , Fenilalanina/farmacologia , Fosfoenolpiruvato/fisiologia , Alanina/farmacologia , Animais , Glucose/farmacologia , Secreção de Insulina , Ilhotas Pancreáticas/efeitos dos fármacos , Masculino , Ratos , Ratos Endogâmicos
2.
Biochem J
; 204(2): 605-8, 1982 May 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-7052071
RESUMO
Pyruvate kinase in rat pancreatic islets was characterized immunologically and kinetically. It is concluded that this activity is predominantly if not totally of the M(2) type.