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1.
Orthop Traumatol Surg Res ; 101(3): 313-7, 2015 May.
Artigo em Inglês | MEDLINE | ID: mdl-25817908

RESUMO

INTRODUCTION: Autogenous osteochondral mosaicplasty is the most common cartilage restoration technique in standard clinical practice. The purpose of this study was to evaluate the return to sports 9 years after mosaicplasty of the femoral condyles. HYPOTHESIS: The long-term results of an osteochondral autograft show that patients can regain their pre-injury activity level. MATERIAL AND METHODS: This study is based on a series of 25 patients with a mean age of 28.9 years (range, 16-44 years) who had stage 3 or 4 chondral lesions of the femoral condyles (according to the ICRS or ICRS-OCD scores). The origin of the lesion was osteochondritis dissecans (13 knees), osteochondral fracture sequelae (ten knees), or aseptic osteonecrosis (two knees). The average size of the lesion was 2.11 ± 0.9 cm(2). Ten patients (40%) had an associated procedure during the osteochondral autograft. The patients were assessed clinically (IKDC and Lysholm-Tegner scores) and radiographically by a reviewer independent of the team of operators. RESULTS: All patients were re-examined at a mean follow-up of 9 years (range, 6-15 years), with 84% satisfied or very satisfied with the procedure. The average IKDC was 74.5 ± 18.5 points. The average Lysholm score was 87.3 ± 11.6 points. The average Tegner score ranged from 6.35 ± 1.53 points prior to surgery to 5.60 ± 1.64 points after surgery (P = 0.001). The average loss was 0.64 points for patients whose presurgery Tegner score was greater than or equal to 7 (P = 0.019) and 0.3 points if lower than 7. The radiologic evaluation of 21 patients showed complete osteointegration of the grafts in 90% of cases. CONCLUSION: The results of the femoral condyle mosaic autografts are satisfactory, a mean of 9 years after surgery. The most active patients lowered their activity level while the more sedentary did not have to adapt their lifestyle.


Assuntos
Transplante Ósseo , Cartilagem/transplante , Fêmur/cirurgia , Volta ao Esporte , Adolescente , Adulto , Cartilagem Articular/diagnóstico por imagem , Cartilagem Articular/lesões , Cartilagem Articular/cirurgia , Epífises/diagnóstico por imagem , Epífises/cirurgia , Feminino , Fêmur/diagnóstico por imagem , Seguimentos , Humanos , Articulação do Joelho/diagnóstico por imagem , Articulação do Joelho/cirurgia , Escore de Lysholm para Joelho , Masculino , Osteocondrite Dissecante/cirurgia , Osteonecrose/cirurgia , Radiografia , Transplante Autólogo , Resultado do Tratamento , Adulto Jovem
2.
Orthop Traumatol Surg Res ; 101(3): 307-11, 2015 May.
Artigo em Inglês | MEDLINE | ID: mdl-25771528

RESUMO

INTRODUCTION: Acute patellar tendon rupture is easy to diagnose but is still often overlooked. The aim of this study was to assess early and late results of surgical treatment of acute patellar tendon rupture. Our hypothesis was that functional outcome is satisfactory. METHODS: A retrospective study included 38 knees in 37 patients (4 female, 33 male). Mean age was 42.6 ± 9.9 years (range, 23-81 years). Lesions comprised 15 tendon body ruptures, 20 avulsions from the tip of the patella and 3 avulsions from the anterior tibial tuberosity. Tendon repair was protected in more than 95% of cases by a reinforcement frame: hamstring (21 cases), synthetic ligament (12 cases) or metallic wire (3 cases). Results were evaluated in 2 steps: on patient files at a mean follow-up of 7.1 months (range, 3-24 months) to assess complications and early functional and radiological results; and by phone at a mean follow-up of 9.3 years (range, 19-229 months) in order to assess long-term functional outcome on Lysholm score and patient satisfaction. RESULTS: Thirty-one knees were assessed at a mean 7.1 months. Mean knee flexion was 128.5° ± 7.5° (range, 85°-150°), extension -1° (range, -15° to 0°) and Caton-Deschamps index 0.96 (range, 0.57-1.29). Twenty-three knees were further assessed at a mean 9.3 years. Mean Lysholm score was 93.7 points (range, 61-100). Ninety-six percent of patients were satisfied or very satisfied with the result. All had returned to their previous job, and 20 had returned to sports activities, including 8 at pretrauma level. CONCLUSION: Patellar tendon rupture has good prognosis if diagnosis and surgical treatment is early.


Assuntos
Ligamento Patelar/lesões , Ligamento Patelar/cirurgia , Traumatismos dos Tendões/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Seguimentos , Humanos , Articulação do Joelho/fisiopatologia , Escore de Lysholm para Joelho , Masculino , Pessoa de Meia-Idade , Patela/cirurgia , Satisfação do Paciente , Amplitude de Movimento Articular , Estudos Retrospectivos , Ruptura/cirurgia , Fatores de Tempo , Adulto Jovem
3.
Orthop Traumatol Surg Res ; 100(2): 213-6, 2014 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-24529850

RESUMO

INTRODUCTION: Quadriceps tendon ruptures are rare and mainly affect patients over 40 years of age who have a systemic disease. The aim of this study was to evaluate the functional and radiological outcomes following surgical repair of acute quadriceps tendon ruptures. METHODS: This retrospective study included 68 knees in 65 patients (three women, 62 men), having an average age of 55.2 ± 13.9 years. The Lysholm and Tegner scores, patient satisfaction, range of motion and X-rays were evaluated. RESULTS: Fifty knees were evaluated with a mean follow-up of 76±67 months (12-253 months). The average Lysholm score was 93.7±10 (range 56-100, median 99) and 49 of 50 knees (98%) had good or very good subjective results. The average Tegner score was 3.4±1.6 (range 1-9, median 4). At the last follow-up, the average active flexion was 133°±10.8° (range 110°-150°, median 130°). Minor or moderate patellofemoral osteoarthritis was found in 24% of knees, but this was attributed to the surgery or initial injury in only 8% of cases. For 97% of active patients, the surgical repair allowed them to return to work in their pre-injury occupations. CONCLUSION: Quadriceps tendon ruptures have a good prognosis if they are diagnosed quickly. Treatment consists of surgery and postoperative immobilization for at least 6 weeks. An intensive rehabilitation protocol is also needed to recover good knee function. LEVEL OF EVIDENCE: Level IV. Retrospective study.


Assuntos
Traumatismos do Joelho/cirurgia , Traumatismos dos Tendões/cirurgia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Moldes Cirúrgicos , Feminino , Seguimentos , Humanos , Escore de Lysholm para Joelho , Masculino , Pessoa de Meia-Idade , Satisfação do Paciente , Amplitude de Movimento Articular , Estudos Retrospectivos , Retorno ao Trabalho , Ruptura/cirurgia , Tempo para o Tratamento , Adulto Jovem
4.
Orthop Traumatol Surg Res ; 97(8): 886-9, 2011 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-22048070

RESUMO

Management of lower limb fractures in children involves many approaches, spanning from conservative treatment to open reduction and internal fixation. A number of intermediate treatments have also been shown to be effective, notably skeletal traction. However, each of these techniques has its own advantages and disadvantages in terms of complications. In this report, we describe two new cases of chronic osteomyelitis that manifested (many years) after childhood skeletal traction. After analysing these two cases, we proposed measures that can be implemented to avoid such complications, along with a simple, appropriate, reproducible treatment approach.


Assuntos
Fixadores Externos/efeitos adversos , Fixação de Fratura/efeitos adversos , Osteomielite/etiologia , Fraturas da Tíbia/terapia , Adulto , Antibacterianos/uso terapêutico , Biópsia , Doença Crônica , Desbridamento/métodos , Diagnóstico Diferencial , Seguimentos , Fixação de Fratura/métodos , Humanos , Imageamento por Ressonância Magnética , Masculino , Osteomielite/diagnóstico , Osteomielite/terapia , Infecções Estafilocócicas/diagnóstico , Infecções Estafilocócicas/etiologia , Infecções Estafilocócicas/terapia , Staphylococcus aureus/isolamento & purificação , Fraturas da Tíbia/diagnóstico
5.
Orthop Traumatol Surg Res ; 96(4): 417-23, 2010 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-20493799

RESUMO

UNLABELLED: The present study sought to assess the clinical and radiological results and long-term joint impact of different techniques of lateral ankle ligament reconstruction. MATERIAL AND METHODS: A multicenter retrospective review was performed on 310 lateral ankle ligament reconstructions, with a mean 13-year-follow-up (minimum FU: 5 years). Male subjects (53%) and sports trauma (78%) predominated. Mean duration of instability was 92 months; mean age at surgery was 28 years. Twenty-eight percent of cases showed subtalar joint involvement. Four classes of surgical technique were distinguished: C1, direct capsular ligamentous complex reattachment; C2, augmented repair; C3, ligamentoplasty using part of the peroneus brevis tendon and C4, ligamentoplasty using the whole peroneus brevis tendon. Clinical and functional assessment used Karlsson and Good-Jones-Livingstone scores; radiologic assessment combined centered AP and lateral views, hindfoot weight-bearing Méary views and dynamic views (manual technique, Telos or self-imposed varus). RESULTS: The majority of results (92%) were satisfactory. The mean Karlsson score of 90 [19-100] (i.e., 87% good and very good results) correlated with the subjective assessment, and did not evolve over time. Postoperative complications (20%), particularly when neurologic, were associated with poorer results. Control X-ray confirmed the very minor progression in degenerative changes, with improved stability; there was, however, no correlation between functional result and residual laxity on X-ray. Unstable and painful ankles showed poorer clinical results and more secondary osteoarthritis. Analysis by class of technique found poorer results in C4-type plasties and poorer control of laxity on X-ray in C1-type tension restoration. DISCUSSION: The present results confirm the interest of lateral ankle ligamentoplasty in the management of instability and protection against secondary osteoarthritis, and of precise lesion assessment (CT-scan/MRI) to adapt surgery to the ligamentary and associated lesions. LEVEL OF EVIDENCE: Level IV. Retrospective therapeutic study.


Assuntos
Articulação do Tornozelo/fisiopatologia , Articulação do Tornozelo/cirurgia , Instabilidade Articular/cirurgia , Ligamentos Laterais do Tornozelo/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Adulto , Idoso , Feminino , Seguimentos , Humanos , Instabilidade Articular/fisiopatologia , Ligamentos Laterais do Tornozelo/fisiopatologia , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias , Estudos Retrospectivos , Resultado do Tratamento
6.
Rev Chir Orthop Reparatrice Appar Mot ; 94(2): 152-9, 2008 Apr.
Artigo em Francês | MEDLINE | ID: mdl-18420059

RESUMO

PURPOSE OF THE STUDY: Fracture of the distal radius with posterior displacement is the most common wrist fracture. Pinning is generally proposed. The problem is that a secondary displacement may persist, even for the least complex fractures. With the advent of the fixed-angle plate with a self-locking screw, we considered using this method in combination with an anterior approach to the radius. We report our preliminary results. MATERIAL AND METHODS: From November 1 to March 31, 2003, among the 195 fractures of the distal radius with posterior displacement which we treated in our unit, 135 were treated with orthopedic reduction, 36 with Kapandji pinning and 24 with a T-shaped anterior locking compression plate (Synthès, LCP 3.5. During the early part of this series, the LCP was used for emergency situations in young adults with a posterior displacement exceeding 20 degrees . Starting in November 2002, the technique was also proposed for revisions for secondary displacements after orthopedic reduction or pinning procedures. Secondary displacement was noted on the standard X-rays and the clinical analysis included a measurement of muscle strength, the DASH score and the clinical evaluation score used by the SOFCOT symposium in November 2000. RESULTS: Twenty-four patients (14 female, 10 male, mean age: 54.5 years) presented 14 extra-articular fractures and ten articular fractures. At admission, mean frontal inclination of the radial glenoid was 13 degrees with a posterior displacement of 25.45 degrees and an ulnar variance measuring+4mm. Eighteen patients were reviewed at mean 16 months follow-up. Mean frontal inclination of the glenoid was 23.95 degrees with mean anteversion 5.45 degrees . Using the SOFCOT criteria, 11 outcomes were anatomic and seven presented moderate displaced healing. The wrist force (Jamar was 95% of the value measured on the healthy side. The mean DASH score was 38.47. Outcome was considered excellent for nine cases, good for six, fair for three and poor for zero. Complications were: reflex dystrophy (n=4), carpal tunnel syndrome (n=1), cheloid scar (n=1), glenoids in the pulse gutter (n=10), and secondary fracture along the upper border of the plate (n=3). CONCLUSION: This study demonstrated that, used on the anterior aspect of the radius, the locking compression plate provides satisfactory treatment for fractures of the distal radius with posterior displacement. Because of the angular stability, the reduction can be maintained over time so that secondary displacement is no longer a problem. This is a difficult technique which requires particular skill. We no longer recommend the LCP 3.5 plate due to the poorly adapted ergonometry, the late fracture over the plate and the fact that the material is not removed.


Assuntos
Placas Ósseas , Fixação Interna de Fraturas/instrumentação , Fraturas do Rádio/cirurgia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Pinos Ortopédicos , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Força Muscular , Procedimentos Ortopédicos , Complicações Pós-Operatórias , Radiografia , Fraturas do Rádio/diagnóstico por imagem , Recuperação de Função Fisiológica , Fatores de Tempo , Resultado do Tratamento , Articulação do Punho/fisiologia
7.
Br J Clin Pharmacol ; 65(2): 180-7, 2008 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-18251757

RESUMO

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: The efficacy of homeopathy is still under debate and a recent meta-analysis recommended further randomized double-blind clinical trials to identify any clinical situation in which homeopathy might be effective. WHAT THIS STUDY ADDS: The complex of homeopathy tested in this study (Arnica montana 5 CH, Bryonia alba 5 CH, Hypericum perforatum 5 CH and Ruta graveolens 3 DH) is not superior to placebo in reducing 24 h morphine consumption after knee ligament reconstruction. AIMS: The efficacy of homeopathy is still under debate. The objective of this study was to assess the efficacy of homeopathic treatment (Arnica montana 5 CH, Bryonia alba 5 CH, Hypericum perforatum 5 CH and Ruta graveolens 3 DH) on cumulated morphine intake delivered by PCA over 24 h after knee ligament reconstruction. METHODS: This was an add-on randomized controlled study with three parallel groups: a double-blind homeopathic or placebo arm and an open-label noninterventional control arm. Eligible patients were 18-60 years old candidates for surgery of the anterior cruciate ligament. Treatment was administered the evening before surgery and continued for 3 days. The primary end-point was cumulated morphine intake delivered by PCA during the first 24 h inferior or superior/equal to 10 mg day(-1). RESULTS: One hundred and fifty-eight patients were randomized (66 in the placebo arm, 67 in the homeopathic arm and 25 in the noninterventional group). There was no difference between the treated and the placebo group for primary end-point (mean (95% CI) 48% (35.8, 56.3), and 56% (43.7, 68.3), required less than 10 mg day(-1) of morphine in each group, respectively). The homeopathy treatment had no effect on morphine intake between 24 and 72 h or on the visual analogue pain scale, or on quality of life assessed by the SF-36 questionnaire. In addition, these parameters were not different in patients enrolled in the open-label noninterventional control arm. CONCLUSIONS: The complex of homeopathy tested in this study was not superior to placebo in reducing 24 h morphine consumption after knee ligament reconstruction.


Assuntos
Analgésicos/administração & dosagem , Homeopatia/métodos , Articulação do Joelho/cirurgia , Ligamentos Articulares/cirurgia , Morfina/administração & dosagem , Procedimentos de Cirurgia Plástica , Adolescente , Adulto , Criança , Feminino , Humanos , Articulação do Joelho/efeitos dos fármacos , Ligamentos Articulares/efeitos dos fármacos , Masculino , Pessoa de Meia-Idade , Dor Pós-Operatória/tratamento farmacológico , Dor Pós-Operatória/prevenção & controle , Procedimentos de Cirurgia Plástica/métodos
8.
Rev Chir Orthop Reparatrice Appar Mot ; 93(4): 351-6, 2007 Jun.
Artigo em Francês | MEDLINE | ID: mdl-17646816

RESUMO

PURPOSE OF THE STUDY: The aim of this work was to assess radiographic outcome after double femoral and tibial osteotomy for severe genu varum. Among 197 computer-assisted osteotomies performed in our department between August 2001 and February 2006, 16 (8.1%) were double level osteotomies. MATERIAL AND METHODS: Five women and nine men, mean age 51.19+/-11.15 years (range 20-63 years) underwent surgery (both sides for two men). The right side was involved in nine cases, the left in seven. Inclusion criteria were genu varum>10 degrees and/or a mechanical femur angle > =90 degrees in a context of a varus tibial mechanical axis. Exclusion criteria were a femoral mechanical angle at 90 degrees and a tibial mechanical angle>88 degrees. Using the modified Ahlbäck classification, the knees were: grade 2 (n=1), grade 3 (n=9), grade 4 (n=4) and grade 5 (n=1). One patient did not present osteoarthritic degradation but a particularly unaesthetic deformity. The radiological femorotibial mechanical angle (HKA) measured preoperatively was on average 168.44 degrees +/-2.42 degrees (range 164 degrees -173 degrees). The average preoperative femoral mechanical angle was 87.38 degrees +/-2.45 degrees (range 81 degrees -90 degrees) and the mechanical tibial angle was 84.5 degrees +/-2.19 degrees (range 80 degrees -88 degrees). The main preoperative objective was to obtain a mechanical femorotibial angle of 182 degrees +/-2 degrees without an oblique joint space giving a tibial mechanical angle of 90+/-2 degrees). All operations were computer-assisted using the Orthopilot navigation system. After acquisition of the mechanical axis, the closed wedge lateral distal femoral osteotomy was performed first to achieve the desired femoral correction. The open wedge proximal medial tibial osteotomy was then performed to obtain the planned femorotibial mechanical axis. A control goniometry in the weight bearing position was obtained three months postoperatively. RESULTS: There were no complications. The mean preoperative computer-measured HKA was 168.63 degrees +/-2.22 degrees (range 164 degrees -173 degrees), i.e. an angle corresponding perfectly with the preoperative goniometry. After the osteotomies, the mean computer-measured mechanical angle was 183 degrees +/-0.94 degrees (range 181 degrees -184 degrees). Three months after the operation, the weight-bearing goniometry gave a mean HKA angle at 181.25 degrees +/-1.84 degrees (range 177 degrees -184 degrees). The mean femoral mechanical angle was 93.13 degrees +/-2.25 degrees (range 89 degrees -97 degrees) and the mean tibial mechanical angle was 90.31 degrees +/-1.20 degrees (range 88 degrees -92 degrees). The preoperative objective was achieved in 14 of the 16 patients (87.5%). The two failures were undercorrections (177 degrees and 179 degrees). Joint spaces were not oblique on the x-rays. DISCUSSION: Tibial osteotomy is an excellent method for the treatment of osteoarthritic genu varum. However, in patients with very severe deformity, femoral varus is also involved so that the overcorrection necessary to achieve a good result (3-6 degrees valgus) could often produce an oblique joint space corresponding to excessive tibial valgus. Since osteotomy is generally considered as a palliative measure before later implantation of a total prosthesis, an oblique joint surface would compromise the success of the subsequent surgery. Double-level osteotomy is a way to avoid this problem, keeping in mind that the risk of over or under correction is not negligible for this difficult operation. We used our experience with computer-assisted navigation for total knee arthroplasty and for tibial osteotomy to prepare this technique for double-level osteotomy. CONCLUSION: Computer-assisted double-level osteotomy is a reliable, accurate and reproducible method for the treatment of severe genu varum. The two failures observed in this series were within a tolerable range (177 degrees and 179 degrees). The use of a navigation procedure simplifies a technique which in general requires skillful application to achieve the preoperative objective. The development of this technique is important in order to avoid an oblique joint space which can compromise the success of subsequent prosthesis implantation.


Assuntos
Fêmur/cirurgia , Joelho/anormalidades , Joelho/cirurgia , Osteotomia/métodos , Cirurgia Assistida por Computador , Tíbia/cirurgia , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Índice de Gravidade de Doença
9.
Rev Chir Orthop Reparatrice Appar Mot ; 87(1): 18-28, 2001 Feb 01.
Artigo em Francês | MEDLINE | ID: mdl-11240534

RESUMO

PURPOSE OF THE STUDY: The aim of this work was to compare the radiographic findings after two techniques for total knee arthroplasty, one using a computer-assisted approach and the other a conventional approach. MATERIAL AND METHODS: Between January 1998 and April 1999, we conducted a prospective study randomizing 25 patients for conventional surgery (group A) and 25 for computer-assisted surgery (group B). All patients volunteered to participate in this study and gave their written informed consent. There were 35 women and 15 men, mean age 69.5 years (range 47-85). The two groups were comparable for age, gender, height, weight, orthopedic history, etiology and preoperative mobility. The preoperative hip-knee angle (HKA) was also comparable between the two groups. Mean HKA was 175 degrees, i.e. 5 degrees varus (range 162 degrees (18 degrees varus) to 210 degrees (30 degrees valgus)). Genu varum was found in 80 p. 100 of the patients in group A and in 76 p. 100 in group B, genu valgum in 16 p. 100 in group A and 24 p. 100 in group B. The same operator performed all the procedures) with the same type ok prosthesis for all patients. The goal of the operation was to position the prosthesis to produce an HKA of 180 +/- 3 degrees, a femoral angle of 90 degrees (from the mechanical axis), a tibial angle of 90 degrees and a posterior tibial slope of 0 degrees (tibial plateau at 90 degrees to the lateral tibial axis). Statview 5 PC was used for the statistical analysis. Comparisons between groups were made with the Student's t test to compare means when the validity conditions were met. RESULTS: The patients were reviewed by two surgeons, independently of the operator and the designers of the computer-assistance program. Mean duration of the procedure was longer in group B (102 mn versus 70 mn, p<0.001). There was no statistically significant difference in mean postoperative bleeding (group A=380 cc, group B=480 cc). The postoperative HKA was 181.2 +/- 2.72 degrees in group A and 179.04 +/- 2.53 degrees in group B (p > 0.05). The HKA was between 177 degrees and 183 degrees in 75 p. 100 of the patients in group A and in 84 p. 100 of those in group B. Implantation of the femoral component showed a mean angle of 91.12 +/- 2.07 degrees in group A and 89.56 +/- 1.61 degrees in group B (p=0.048). The mean tibial angle was 90.167 +/- 1.61 degrees in group A and 89.5 +/- 1.34 degrees in group B (p=0.11). On the lateral view, the femoral component was at 90 degrees to the mechanical axis in 16/21 patients in group B. These data were missing in group A. The posterior tibial slope was 90.76 +/- 2.19 degrees in group A and 89.44 +/- 2.14 in group B (p=0.18). CONCLUSION: Computer-assisted surgery for total knee arthroplasty was found to provide remarkably reliable results. Once the "growing pains" of this new material have been mastered, all surgeons should be able to expect an improvement in the positioning of prosthetic implantations.


Assuntos
Artroplastia do Joelho/métodos , Radiografia Intervencionista/métodos , Terapia Assistida por Computador/instrumentação , Terapia Assistida por Computador/métodos , Tomografia Computadorizada por Raios X/métodos , Idoso , Idoso de 80 Anos ou mais , Artroplastia do Joelho/efeitos adversos , Fenômenos Biomecânicos , Estatura , Peso Corporal , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Radiografia Intervencionista/instrumentação , Amplitude de Movimento Articular , Tomografia Computadorizada por Raios X/instrumentação , Resultado do Tratamento
10.
Arch Mal Coeur Vaiss ; 75(3): 349-56, 1982 Mar.
Artigo em Francês | MEDLINE | ID: mdl-6807252

RESUMO

The authors report a case of early postoperative thrombosis of a Starr-Edwards mitral valve prosthesis in a 36 year old female who had undergone closed heart surgery nine years previously for tight mitral stenosis. Severe restenosis led to mitral valve replacement in 1980, and the insertion of a Starr-Edwards prosthesis. On the 8th postoperative day thrombosis of the prosthesis presented with pulmonary oedema and a change in the prosthetic valve sounds which regressed with therapy. The diagnosis was confirmed on the 9th postoperative day by left heart catheterisation and angiography. Fibrinolytic treatment was instituted on the 10th postoperative day with 4500 u/Kg of Urokinase for 24 hours. Pulmonary oedema regressed at the 6th hour of treatment and the prosthetic valve sounds reverted to normal. No significant complication was observed. The good result has been maintained up to the 6th postoperative month. This case demonstrates the possibility of using fibrinolytic therapy in the early postoperative period after valve replacement: this should be weighed in the balance against the mortality of reoperation in such cases of early thrombosis of prosthetic heart valves.


Assuntos
Doença das Coronárias/etiologia , Fibrinolíticos/uso terapêutico , Próteses Valvulares Cardíacas/efeitos adversos , Adulto , Doença das Coronárias/tratamento farmacológico , Feminino , Humanos , Complicações Pós-Operatórias , Ativador de Plasminogênio Tipo Uroquinase/uso terapêutico
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