Cross-sectional Study of Factors Associated With Suicide Ideation in Ontario Adolescents.

OBJECTIVE: Suicide is the second leading cause of death in Canadian adolescents. The Interpersonal Theory of Suicide attempts to explain suicide etiology and proposes that feelings of perceived burdensomeness or thwarted belongingness lead to suicide ideation, but this has not been extensively studied in adolescents. This study aimed to use the Interpersonal Theory of Suicide to examine factors that may be associated with suicide ideation in adolescents. The factors of interest were school connectedness, perceived availability of support, self-esteem, feelings of worthlessness, feelings of hopelessness, bullying and cyberbullying victimization, substance use, and social media use. METHODS: Data were from the 2017 Ontario Student Drug Use and Health Survey, a survey of 7th to 12th graders enrolled in a publicly funded school in Ontario. Weighted multivariate logistic regression of suicide ideation on all exposure variables was conducted. RESULTS: 13.6% of students in the sample endorsed having suicidal ideation in the preceding 12 months. Not knowing where to turn to for support, feeling worthless, endorsing low self-esteem, being bullied, and using cannabis were each associated with greater odds of suicide ideation. Feeling hopeless, social media use, using alcohol and tobacco, and being cyberbullied were not associated with suicide ideation in the weighted multivariate logistic regression model. CONCLUSIONS: This study is consistent with the Interpersonal Theory of Suicide as low self-esteem and feelings of worthlessness, two indicators of perceived burdensomeness, and not knowing where to turn to for support, an indicator of thwarted belongingness, were associated with greater odds of suicide ideation. These findings can help guide interventions aimed at reducing the burden of suicidality during adolescence and demonstrate the need to provide accessible mental health support for youth.

Trying is believing: A pilot study of in-vivo nicotine replacement therapy sampling in disadvantaged Black adults who smoke cigarettes.

INTRODUCTION: While nicotine replacement therapy (NRT) is a frontline tobacco treatment that doubles smoking quit rates, only about 18% of Black adults who smoke cigarettes report lifetime use of NRT. A promising approach for increasing NRT use is in-session (in-vivo) NRT sampling within cessation interventions. The present pilot study examined the effectiveness of an in-vivo NRT sampling intervention within a single-session, culturally-targeted motivational intervention trial in Black adults who smoke cigarettes. METHODS: Non-treatment-seeking disadvantaged Black adults (N = 60) were offered the choice to sample nicotine lozenge, patch, or both in-session with the counselor present. Regardless of their choice, they were offered a one-week starter kit of both products. Data were analyzed at baseline and 1-month follow-up. Primary outcomes were 1) differences in motivation to quit smoking among NRT samplers versus non-samplers, 2) in-vivo NRT sampling preferences, and 3) in-vivo sampling's association with NRT use and improved smoking outcomes at follow up. RESULTS: Almost all participants accepted a take-home NRT starter kit, and approximately half of those offered in-vivo sampling agreed to sample. Participants preferred sampling lozenges in session (75.8% lozenge only vs. 12.1% nicotine patch only or 12.1% both; p < .001). Motivation to quit smoking was not related to likelihood of in-vivo NRT sampling (p > .05). At 1-month follow-up, in-vivo samplers were more likely to use NRT (94% vs. 35%, respectively; p < .001) and report a quit attempt (81.8% vs. 53.9%, p < .05) compared to non-samplers. CONCLUSION: In-vivo NRT sampling is a promising strategy to improve NRT uptake among Black adults who smoke cigarettes, regardless of motivation to quit smoking.

Acute alcohol rewarding effects as a risk factor for hangover frequency.

BACKGROUND/PURPOSE: Acute subjective alcohol effects appear to play an important role in predicting alcohol hangover. However, no studies have used a laboratory-based alcohol challenge to examine the concurrent or longitudinal effects of subjective alcohol responses on hangover frequency. As such, we investigated the direct and indirect effects of alcohol stimulation, sedation, liking and wanting, as measured in a controlled setting, on hangover frequency over five years. METHOD: Participants were 294 young adult light-to-heavy social drinkers (aged 21-35 years, 42% female) enrolled in the Chicago Social Drinking Project. The study utilized a placebo-controlled, double blind, laboratory alcohol challenge and a battery of measures including the Biphasic Alcohol Effects Scale, Drug Effects Questionnaire, Hangover Symptom Scale, and alcohol use Quantity-Frequency Interview, with the latter two re-administered after five years. RESULTS: Through the use of a path analysis, the present study found significant direct effects from alcohol liking to hangover frequency at initial testing. In addition, there were multiple significant indirect effects from greater alcohol liking and wanting to greater alcohol use quantity-frequency and, in turn, greater hangover frequency at initial testing and 5-year follow-up. Last, there were significant indirect effects from greater alcohol sedation to less alcohol use quantity-frequency and, in turn, less hangover frequency at initial testing and 5-year follow-up. CONCLUSION: This study highlights the role of the hedonic reward and motivational salience of alcohol as potential mechanisms of alcohol-related consequences (i.e., hangover) among light-to-heavy social drinking young adults.

Associations of antidepressant use with alcohol use and problem drinking: Ontario population data from 1999 to 2017.

OBJECTIVE: This study investigated the rates of and change in past-year antidepressant use from 1999 to 2017 among a representative sample of Ontario adults and past-year alcohol users and problem drinkers. It examined whether alcohol use and problem drinking are associated with antidepressant use over time, whether gender moderated the effect of problem drinking on antidepressant use, and the potential correlates of past-year antidepressant use. METHOD: This study utilized data from the Centre for Addiction and Mental Health Monitor study, a repeat cross-sectional telephone survey of the Ontario general adult population. Data are from 15 annual cycles of the survey 1999-2017 (where relevant variables were included), resulting in a sample size of N = 35,210. Variables of interest included demographic variables, past-year antidepressant use, past-year alcohol use, and past-year problem drinking (e.g., 8+ on the Alcohol Use Disorders Identification Test). RESULTS: Past-year antidepressant use increased from 1999 to 2017 similarly among the full sample, past-year alcohol users, and past-year problem drinkers. Approximately 9% of Ontarians reported past-year antidepressant use in 2017. Overall, past-year problem drinkers were 1.5 times more likely to use antidepressants than non-problem drinkers. Past-year alcohol use was not associated with antidepressant use. Gender moderated the association between past-year problem drinking and antidepressant use. CONCLUSION: This study determined that past-year antidepressant use increased from 1999 to 2017, that past-year problem drinkers are more likely to use antidepressants than non-problem drinkers, and that past-year problem drinking is associated with past-year antidepressant use among women but not among men.

RéSUMé: OBJECTIF: Cette étude a examiné les taux et l'évolution de la consommation d'antidépresseurs au cours de la dernière année de 1999 à 2017 parmi un échantillon représentatif d'adultes de l'Ontario et de consommateurs d'alcool et de buveurs problématiques au cours de l'année précédente. Il a examiné si la consommation d'alcool et la consommation problématique d'alcool sont associées à la consommation d'antidépresseurs au fil du temps, si le sexe modère l'effet de la consommation problématique d'alcool sur l'utilisation d'antidépresseurs, et les corrélats potentiels de l'utilisation d'antidépresseurs au cours de l'année précédente. MéTHODE: Cette étude a utilisé les données de l'étude Monitor du Centre de toxicomanie et de santé mentale, une enquête téléphonique transversale répétée auprès de la population adulte générale de l'Ontario. Les données proviennent de 15 cycles annuels de l'enquête 1999­2017 (où les variables pertinentes ont été incluses), ce qui donne une taille d'échantillon de N = 35 210. Les variables d'intérêt comprenaient les variables démographiques, la consommation d'antidépresseurs au cours de la dernière année, la consommation d'alcool au cours de la dernière année et la consommation excessive d'alcool au cours de la dernière année (par exemple, 8+ au Alcohol Use Disorders Identification Test). RéSULTATS: La consommation d'antidépresseurs au cours de la dernière année a augmenté de 1999 à 2017 de la même manière parmi l'échantillon complet, les consommateurs d'alcool de l'année précédente et les buveurs à problèmes de l'année précédente. Environ 9 % des Ontariennes et Ontariens ont déclaré avoir utilisé des antidépresseurs au cours de l'année précédente en 2017. Dans l'ensemble, les buveurs à problèmes au cours de la dernière année étaient 1,5 fois plus susceptibles de prendre des antidépresseurs que les buveurs sans problème. La consommation d'alcool au cours de la dernière année n'a pas été associée à l'utilisation d'antidépresseurs. Le sexe a modéré l'association entre la consommation abusive d'alcool et l'utilisation d'antidépresseurs au cours de l'année précédente. CONCLUSION: Cette étude a déterminé que l'utilisation d'antidépresseurs au cours de la dernière année a augmenté de 1999 à 2017, que les buveurs à problèmes de l'année précédente sont plus susceptibles d'utiliser des antidépresseurs que les buveurs sans problème, et que la consommation excessive d'alcohol au cours de la dernière année est associée à l'utilisation d'antidépresseurs au cours de la dernière année pour les femmes mais pas pour les hommes.

Effects of a brief motivational smoking intervention in non-treatment seeking disadvantaged Black smokers.

Objective: While the U.S. adult smoking rate has declined, Black smokers disproportionately face more barriers to accessing brief effective tobacco cessation treatments compared with other racial groups. This study developed and tested the effects of a novel, evidence-based, brief smoking intervention culturally targeted for disadvantaged Black smokers (ClinicalTrials.gov ID: NCT04460417). Method: In this randomized controlled trial, primarily low-income Black non-treatment-seeking smokers (N = 204, 51% female) were randomized to enhanced care (EC) or treatment as usual (TAU). The EC group received a 30-min session with personal feedback on smoking, education on health outcomes and tobacco advertising targeting Black smokers, and nicotine replacement therapy (NRT) starter kits. TAU included provision of self-help materials. Primary outcome was motivation to change smoking behavior, and secondary outcomes included NRT knowledge and use, quit attempts, and number of cigarettes smoked per day. Data were collected at baseline, 1- and 6-month follow-ups. Results: Compared with TAU, EC increased motivation to change (p = .02), accuracy in NRT knowledge, (p < .001), NRT use (p = .01), and likelihood of making a serious quit attempt as well as reduced cigarettes smoked per day (p < .01) through 6-month follow-up. Conclusions: A brief motivational intervention for Black non-treatment-seeking smokers increased motivation to change smoking and resulted in improvements in NRT knowledge, use, and quit-relevant behaviors. Findings support cultural-targeting and provision of NRT to enhance motivation in Black smokers to reduce cultural and institutional barriers to tobacco cessation. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Subjective alcohol responses in high- and low-risk adolescents: results from the Dresden Longitudinal Study on Alcohol Use in Young Adults.

BACKGROUND AND AIMS: Research shows that sensitivity to certain alcohol responses conveys risk for problem drinking. This study aimed to determine if high-risk adolescent drinkers infuse more alcohol and experience greater alcohol-induced stimulation and wanting and less sedation than low-risk adolescent drinkers. DESIGN AND PARTICIPANTS: Ninety-two low- (n = 38) and high-risk (n = 54) adolescent drinkers, as determined by Alcohol Use Disorders Identification Test scores of < 6 or ≥ 6, respectively, participated in the Dresden Longitudinal Study on Alcohol Use in Young Adults in which intravenous alcohol self-administration was examined in a mixed within- and between-subjects design. SETTING: Technische Universität Dresden. Dresden, Germany. MEASUREMENTS: Predictors were drinking status (high- versus low-risk), time and their interactions. Outcomes were arterial blood alcohol concentration (aBAC); alcohol-induced stimulation, sedation and wanting assessed at baseline, 10 (alcohol prime), 45, 65, 85, 105, 125 and 145 minutes. Covariates were family history of alcohol use disorder, sex and aBAC. RESULTS: The alcohol prime dose produced similar sharp increases in stimulation and sedation in high- and low-risk drinkers (time P < 0.001; group × time P > 0.05). During self-administration, high-risk drinkers reached higher aBACs (P = 0.028) at a faster rate (group × time P < 0.001), and experienced further increases in stimulation (group × time P = 0.005) but with similar sedation (group × time P = 0.794) than in low-risk drinkers. High-risk drinkers also exhibited greater tonic alcohol wanting (group P = 0.003) throughout the session. CONCLUSIONS: High-risk adolescent drinkers appear to have heightened sensitivity to alcohol-induced stimulation and tonic high levels of wanting compared with low-risk adolescent drinkers.

White wine processing by UHPH without SO2. Elimination of microbial populations and effect in oxidative enzymes, colloidal stability and sensory quality.

The use of UHPH sterilization in the absence of SO2 has been used to eliminate wild microorganisms and inactivate oxidative enzymes. A white must of the Muscat of Alexandria grape variety was continuously processed by UHPH at 300 MPa (inlet temperature: 23-25 °C). The initial microbial load of the settled must was 4-log CFU/mL for both yeast and moulds, and slightly lower for bacteria. After UHPH processing, no microorganisms were detected in 1 mL. UHPH musts remain without fermentative activity for more than 60 days. Concentrations of the thermal markers indicated the absence of thermal damage in the UHPH-treated musts, since 5-hydroxymethylfurfural was not detected. In addition, the must treated by UHPH keeps terpene concentrations similar to those of the untreated controls. A strong inactivation of the oxidative enzymes was observed, with no browning at room temperature for more than 3 days. The antioxidant value of the UHPH-treated must was 156% higher than the control.

Relationships between generalized impulsivity and subjective stimulant and sedative responses following alcohol administration.

Impulsivity and subjective response (SR) to alcohol (i.e., individual differences in sensitivity to pharmacologic alcohol effects) are both empirically supported risk factors for alcohol use disorder; however, these constructs have been infrequently studied as related risk factors. The present investigation examined a self-report measure of impulsivity (i.e., the Barratt Impulsiveness Scale, Version 11) in relation to acute alcohol effects (i.e., stimulant and sedative SR). Participants came from 2 cohorts of the Chicago Social Drinking Project. Heavy and light drinkers from Cohort 1 (n = 156) and heavy social drinkers from Cohort 2 (n = 104) were examined using identical laboratory protocols following oral alcohol administration using a within-subject, double-blind, placebo-controlled laboratory study design. Self-reported impulsivity and, for comparison purposes, sensation seeking were measured at baseline, and SR was measured once prior to and 4 times following alcohol administration. More impulsive light, but not heavy, drinkers reported heightened stimulant SR following alcohol administration. High impulsive, light drinkers reported stimulant SR at a magnitude similar to that for heavy drinkers, whereas low impulsive, light drinkers reported limited stimulant SR. The interaction between impulsivity and sensation seeking did not statistically predict stimulant SR, and overall, impulsivity was a stronger predictor than was sensation seeking. However, impulsivity was not statistically predictive of dampened sedative SR among light or heavy drinkers. These findings partially replicate and extend the recent literature linking self-reported impulsivity to heightened stimulant SR from alcohol. Future directions include longitudinal studies and research relating multiple facets of impulsivity to SR. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

A pilot study of Counsel to Quit®: Evaluating an Ask Advise Refer (AAR)-based tobacco cessation training for medical and mental healthcare providers.

INTRODUCTION: Despite tobacco use as the largest preventable cause of premature death in the US, many healthcare providers continue to lack the knowledge and confidence in employing the Ask, Advise, Refer (AAR) model in tobacco cessation treatment delivery. This pilot study evaluated the feasibility and effectiveness of a novel AAR-styled training program, Counsel to Quit®, across a range of healthcare providers and disciplines (i.e., medical, mental health, other). The Counsel to Quit® training program primarily targeted publically-funded settings that serve communities with high smoking rates. METHODS: Pre- and post-training surveys were administered to medical, mental health, and other professionals (N = 297) to evaluate the effectiveness of the 60-90 minute Counsel to Quit® counselor training program for improving confidence in the ability to discuss approved tobacco cessation interventions and address the current state of knowledge about the role of electronic cigarettes in tobacco cessation. The trainings were held across 14 different non-profit institutional settings in Chicago, IL. RESULTS: The Counsel to Quit® program improved AAR beliefs, the confidence and ability to discuss smoking cessation, and knowledge on the role of electronic cigarettes in tobacco cessation among medical, mental health, and other providers (ps < .001). Interactions showed that Counsel to Quit® improved medical provider confidence in referring patients for smoking cessation the most (p < .001), and also improved mental health providers belief in the importance of tobacco cessation for preventative care the most (ps < .05). CONCLUSIONS: Counsel to Quit® is a feasible and effective training for improving AAR beliefs across multiple healthcare provider domains and at different types of publicly-funded healthcare institutions. Further, this training increased provider preparedness to discuss the lack of evidence for e-cigarette use as a form of tobacco cessation.

Self-report measures of loss of control over eating: Psychometric properties in clinical and non-clinical samples.

OBJECTIVE: Research evidence supports the clinical significance of subjective feelings of loss of control over eating; however, limited attention has been given to how this construct is assessed. Two measures have been developed in recent years (i.e., Eating Loss of Control Scale [ELOC] and Loss of Control over Eating Scale [LOCES]), but further validation in clinical and non-clinical samples is needed. METHOD: The current study evaluated the psychometric properties, including factor structure, criterion validity, and measurement invariance of the ELOC and LOCES across two groups: (a) a clinical sample of individuals with eating disorders (n = 106) and (b) a non-clinical sample of college students (n = 321). RESULTS: Confirmatory factor analyses indicated that the 16-item version of the ELOC and 7-item brief version of the LOCES provided good fit to the data in both samples. These measures were highly correlated (r = .83-.87) and associated with binge-eating and related psychopathology. The ELOC demonstrated partial invariance between men and women and between the clinical and non-clinical samples. The LOCES-brief demonstrated full invariance between men and women and partial invariance between the clinical and non-clinical samples. DISCUSSION: Findings suggest that the 16-item ELOC and 7-item LOCES are reliable measures of severity of loss of control eating in clinical and non-clinical samples. Given the brevity of the LOCES-brief and evidence for measurement invariance across sex, it is recommended over the ELOC in heterogeneous samples. Future research is needed to confirm the validity of these measures across individuals with and without eating disorders.

Hangover in Post-College-Aged Drinkers: Psychometric Properties of the Hangover Symptom Scale (HSS) and the Hangover Symptom Scale-Short Form (HSS-5).

BACKGROUND: Alcohol hangovers have been found to be a common and costly consequence of alcohol misuse. However, there is only limited psychometric support for instruments to accurately measure hangovers beyond the college-age years. This study investigated the psychometric properties of the Hangover Symptom Scale (HSS) and the Hangover Symptom Scale-Short Form (HSS-5) including the internal consistency, convergent and discriminant validity, construct validity, and the measurement invariance of these scales between light and heavy drinkers, individuals with a positive and negative family history of alcohol use disorder (AUD), and men and women in a post-college-aged sample. The association of the HSS and HSS-5 with alcohol use problems was also tested. METHODS: Participants were 294 nonalcoholic light and heavy social drinkers (age range 21 to 35 years; 57.8% male) enrolled in the Chicago Social Drinking Project. They completed the HSS as part of a take-home packet completed outside of the laboratory. The psychometric properties of the HSS and HSS-5 were tested. RESULTS: Stronger psychometric support was found for the HSS-5 relative to the full HSS. While both measures demonstrated strong internal consistency reliability, convergent and discriminant validity, and an association with alcohol use problems, only the HSS-5 showed construct validity as determined by confirmatory factor analysis. Further, only the HSS-5 showed measurement invariance between men and women, light and heavy drinkers, and individuals with a positive and negative family history of AUD. CONCLUSIONS: This was the first study to examine the psychometric properties of the HSS and HSS-5 in a post-college-aged sample and the first to investigate the measurement invariance of these measures as a function of sex, drinking history, and family history of AUD. This study supports the use of the HSS-5 as a reliable and valid brief measure of frequency of hangover symptoms.

Hoarding Behaviors and Alcohol Use: The Mediating Role of Emotion Dysregulation.

BACKGROUND: Despite recent research establishing high rates of comorbidity between hoarding disorder and alcohol use disorders (AUD), no studies have systemically examined the associations between symptoms of hoarding and alcohol use. Moreover, no studies have explored potential mechanisms that may help to explain these relations. OBJECTIVES: Thus, the current study was designed to examine the associations between hoarding and AUD symptoms, as well as the mediating role of emotion dysregulation. METHODS: Self-report measures of hoarding, depression, anxiety, alcohol use, and emotion regulation were collected in a sample of 574 adults (M age = 35.43, SD = 12.57; 62% female). RESULTS: Even when controlling for depression and anxiety, AUD symptoms were associated with overall hoarding severity (ß =.23, p <.001) as well as acquiring symptoms (ß =.16, p =.03). Further, the relation between hoarding symptoms and AUD symptoms was mediated by difficulties regulating emotions (B =.04, 95% CI [.02,.06]). Conclusions/Importance: Results of the current study suggest that increased alcohol use may be one way in which individuals with hoarding symptoms attempt to regulate their emotions.

Probability and correlates of dependence among regular users of alcohol, nicotine, cannabis, and cocaine: concurrent and prospective analyses of the National Epidemiologic Survey on Alcohol and Related Conditions.

OBJECTIVE: Research on the progression from substance use to dependence typically relies on lifetime retrospective reports of dependence among ever users. We sought to evaluate probability and correlates of dependence among recent (past-year) weekly users of alcohol, nicotine, cannabis, and cocaine through cross-sectional and prospective analyses. METHODS: Data on substance use (assessed by the Alcohol Use Disorder and Associated Disabilities Interview Schedule-IV) and DSM-IV psychiatric disorders were assessed in 2 waves (Wave 1, N = 43,093; Wave 2, N = 34,653) through the National Epidemiologic Survey on Alcohol and Related Conditions. RESULTS: Conditional risk of dependence varied by frequency of substance use, although it was relatively stable for nicotine use. Among weekly past-year substance users at Wave 1, rates of dependence when rates of past-year dependence at Wave 1 were combined with new cases of dependence reported at Wave 2 were 15.6% for alcohol, 25.0% for cannabis, and 67.3% for nicotine. For past-year weekly users of cocaine at Wave 1, 49.9% met criteria for past-year dependence. Multiple demographic characteristics and past-year psychiatric disorders were correlated with past-year dependence, even among daily users. Men were generally more likely than women to be dependent on alcohol, cannabis, and cocaine, although women were more likely to be dependent on nicotine. Prospective analyses indicated that depressive disorders at Wave 1 predicted subsequent development of alcohol dependence (odds ratio [OR] = 1.40; 95% CI, 1.19-1.65; P < .05). Further, 33.5% of weekly tobacco smokers who were nondependent at Wave 1 developed dependence later on. CONCLUSIONS: The present findings highlight the importance of frequency of use when determining the addictiveness of substances and suggest that certain demographic variables and psychiatric disorders are associated with substance dependence even among regular substance users.

Suicidality prospectively predicts greater urges to smoke following a cessation attempt: Mediation through perceived barriers to cessation.

Growing interest in developing more effective smoking cessation treatments has facilitated the need to further investigate cognitive-affective factors that inhibit successful smoking cessation, such as urges to smoke. Research has strongly supported an association between suicidality and smoking, yet no work has investigated whether suicidality may increase urges to smoke. The current study sought to evaluate the impact of suicidality on smoking-related cognitive-affective factors predictive of smoking relapse among a community sample of 209 daily smokers engaged in a smoking cessation program. Structural equation modeling (SEM) was used to test the effects of self-reported pre-cessation suicidality on urges to smoke 1 month post-cessation as well as whether this effect was mediated by greater barriers to cessation. Results indicated that internal barriers to cessation significantly mediated the effect of pre-cessation suicidality on greater urges to smoke 1 month following smoking cessation attempt. These findings suggest that elevated suicidality may affect perceived internal barriers to cessation and subsequently urges to smoke 1 month following a quit attempt.

Decomposing the Relationship Between Anxiety Sensitivity and Alcohol Use.

OBJECTIVE: The misuse of alcohol is related to numerous detrimental health effects. Research has determined anxiety sensitivity (AS) to be a risk factor for problematic alcohol use. To date, no studies have investigated this relationship using a bifactor model of AS. This study used a bifactor model to determine the effects of the general AS factor and the cognitive, physical, and social concerns subfactors on alcohol-related outcomes. METHOD: The sample consisted of 329 participants selected from a larger sample of individuals in a brief smoking-cessation intervention. Latent factor models were used to determine the effects of the bifactor model of AS on alcohol use behavior. RESULTS: The general AS factor was significantly associated with alcohol use problems but not alcohol consumption. The AS subfactors of cognitive, physical, and social concerns were not significantly related to either alcohol variable. CONCLUSIONS: The findings are inconsistent with previous research that has found associations between the AS subfactors and alcohol-related outcomes. The use of a bifactor model of AS allowed the variance associated with AS to be parceled out of the subfactors, indicating that general AS accounts for the relationship between AS and alcohol misuse.

The effects of Present Hedonistic Time Perspective and Past Negative Time Perspective on substance use consequences.

BACKGROUND: The overuse of substances can lead to economic, physical, and social consequences. Previous research has demonstrated associations between time perspective and frequency of substance use, but no studies have investigated time perspective's effect on substance use consequences. This study aimed to fill this gap in the literature. METHODS: Using an MTurk sample (N=531), latent factor models tested the hypothesis that both Present Hedonistic Time Perspective (PrHTP) and Past Negative Time Perspective PaNTP positively predict alcohol and illicit drug use consequences. Bootstrap analyses were then used to test the hypothesis that PrHTP indirectly affected the relationship between PaNTP and alcohol and illicit drug use consequences. RESULTS: PrHTP significantly predicted alcohol and illicit drug use consequences. PaNTP also significantly predicted alcohol and illicit drug use consequences. PrHTP was found to indirectly affect the relationship between PaNTP and substance use consequences for both alcohol and illicit drugs. CONCLUSIONS: The findings are consistent with previous research and introduce time perspective as an individual differences risk factor for substance use consequences. The partial and full indirect effects are consistent with the idea that individuals with a PaNTP may develop a PrHTP, placing them at risk for substance use consequences.

Quality of life and risk of psychiatric disorders among regular users of alcohol, nicotine, and cannabis: An analysis of the National Epidemiological Survey on Alcohol and Related Conditions (NESARC).

Research is limited on the effects of regular substance use on mental health-related outcomes. We used a large nationally representative survey to examine current and future quality of life and risk of psychiatric disorders among past-year regular (weekly) users of alcohol, nicotine, and cannabis. Data on psychiatric disorders and quality of life from two waves (Wave 1 N = 43,093, Wave 2 N = 34,653) of the National Epidemiological Survey on Alcohol and Related Conditions (NESARC) were used to test study aims. In cross-sectional analyses, regular nicotine and cannabis use were associated with higher rates of psychiatric disorder, though regular alcohol use was associated with lower rates of disorders. Prospective analyses found that regular nicotine use predicted onset of anxiety, depressive, and bipolar disorders. Regular alcohol use predicted lower risk of these disorders. Regular cannabis use uniquely predicted the development of bipolar disorder, panic disorder with agoraphobia, and social phobia. Lastly, regular alcohol use predicted improvements in physical and mental health-related quality of life, whereas nicotine predicted deterioration in these outcomes. Regular cannabis use predicted declines in mental, but not physical health. These data add to the literature on the relations between substance use and mental and physical health and suggest increased risk of mental health problems among regular nicotine and cannabis users and better mental and physical health among regular alcohol users. Examination of mechanisms underlying these relationships is needed.

Examining the factor structure and etiology of prosociality.

Prosociality is one construct included in the developmental propensity model proposed by Lahey and Waldman (2003, 2005) to explain the development of conduct problems in childhood and adolescence. Findings from previous literature on 2 facets of prosociality, dispositional sympathy and respect for rules, suggest that both may have genetic and nonshared environmental influences, but only the latter may have shared environmental influence. The goal of the current article was to explore the structure of the prosociality disposition from a measurement perspective as well as to examine the etiology of this construct. The sample consisted of 686 twin pairs ages 7 to 13. Parents rated their children's prosociality using the Child and Adolescent Dispositions Scale. The factor structure of the prosociality scale was examined using confirmatory factor analysis to compare a 1-factor model with a 2-factor model. Twin analyses were used to examine the proportion of variance associated with genetic and environmental effects on the latent factor(s) from the best fitting model. Results of the current study suggest that prosociality is a disposition that can be conceptualized as 2 related factors rather than a unitary dimension. These 2 factors map onto the subscales of the prosociality dimension (dispositional sympathy and respect for rules). Both factors had significant genetic and nonshared environmental influences, but only respect for rules had significant shared environmental influences. Examining the dispositional sympathy and respect for rules facets of prosociality separately allowed for the discovery that shared environmental factors may have more impact on respect for rules than sympathy.

The Effects of Self-Regulation and Self-Efficacy on Substance Use Abstinence.

Previous research found that self-regulation and self-efficacy were linked to substance use abstinence. The present study examined the relationships between changes in self-regulation and self-efficacy as predictors of substance use abstinence. A total of 150 adult individuals (62% female; M age = 37.1 SD = 8.1; 38% male) in substance abuse recovery participated in a randomized, longitudinal study comparing a communal housing model versus usual aftercare. Both the change in self-regulation (p = .014) and the change in self-efficacy (p = .032) were significantly predictive of the likelihood of abstinence. Additionally, changes in self-regulation and self-efficacy were largely independent. These findings suggest future research for examining change in self-regulation and self-efficacy substance abuse research.

Actividad antimicrobiana con dos tipos de agentes auxiliares en la instrumentación de conductos radiculares. Estudio in vivo en perros / Antimicrobial activity after the use of two different kinds of antiseptic solutions as auxiliary in instrumentation of radicular dental tubes. Experimental trial in dogs

En 30 dientes en buenas condiciones de salud, en perros como animales de experimentación, se formaron cinco grupos de seis dientes de cada uno, tomando dos dientes de cada grupo para las diferentes substancias; se eliminó la corona clínica de cada diente, dejando expuestos los conductos radiculares a contaminación de los líquidos bucales propios del perro, por período de 7 días para el grupo A, 14 días para el grupo B, 21 días para el grupo C, 28 días para el grupo D y 35 días para el grupo E. Se realizó la técnica de instrumentación lateral modificada en cada uno de los dientes; para evaluar la efecividad antimicrobiana las substancias que se utilizaron fueron: Amosan, EDTA e hipoclorito de sodio al 1 por ciento, en dos dientes de cada grupo. Los resultados se basaron en la información obtenida de una siembra bacteriológica, en un medio de cultivo agar-gelosa-sangre y del conteo de unidades formadoras de colonias. Los diferentes tipos de bacterias presente, se evaluaron empleando la técnica de tinción de Gram, los resultados obtenidos muestran que Amosan obtiene un 100 por ciento de efectividad antimicrobiana en más de un caso