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1.
Sensors (Basel) ; 23(17)2023 Aug 25.
Artigo em Inglês | MEDLINE | ID: mdl-37687861

RESUMO

Microwave medical sensing and imaging (MMSI) has been a research hotspot in the past years. Imaging algorithms based on electromagnetic inverse scattering (EIS) play a key role in MMSI due to the super-resolution phenomenon. EIS problems generally employ far-field scattered data to reconstruct images. However, the far-field data do not include information outside the Ewald's sphere, so theoretically it is impossible to achieve super resolution. The reason for super resolution has not been clarified. The majority of the current research focuses on how nonlinearity affects the super-resolution phenomena in EIS. However, the mechanism of super-resolution in the absence of nonlinearity is routinely ignored. In this research, we address a prevalent yet overlooked problem where the image resolution due to scatterers of extended structures is incorrectly analyzed using the model of point scatterers. Specifically, the classical resolution of EIS is defined by the Rayleigh criterion which is only suitable for point-like scatterers. However, the super-resolution in EIS is often observed for general scatterers like cylinders, squares or Austria shapes. Subsequently, we provide theoretical results for the Born approximation framework in EIS, and employ the Sparrow criteria to quantify the resolution for symmetric objects of extended structures. Furthermore, the modified Sparrow criterion is proposed to calculate the resolution of asymmetric scatterers. Numerical examples show that the proposed approach can better explain the super-resolution phenomenon in EIS.

2.
Sensors (Basel) ; 24(1)2023 Dec 28.
Artigo em Inglês | MEDLINE | ID: mdl-38203056

RESUMO

Microwave medical sensing and imaging (MMSI) is a highly active research field. In MMSI, electromagnetic inverse scattering (EIS) is a commonly used technique that infers the internal characteristics of the diseased area by measuring the scattered field. It is worth noting that the image formed by EIS often exhibits the super-resolution phenomenon, which has attracted much research interest over the past decade. A classical perspective is that multiple scattering leads to super-resolution, but this is subject to debate. This paper aims to analyze the super-resolution behavior for Born-iterative-type algorithms for the following three aspects. Firstly, the resolution defined by the traditional Rayleigh criterion can only be applied to point scatterers. It does not suit general scatterers. By using the Sparrow criterion and the generalized spread function, the super-resolution condition can be derived for general scatterers even under the Born approximation (BA) condition. Secondly, an iterative algorithm results in larger coefficients in the high-frequency regime of the optical transfer function compared to non-iterative BA. Due to the anti-apodization effect, the spread function of the iterative method becomes steeper, which leads to a better resolution following the definition of the Sparrow criterion mentioned above. Thirdly, the solution from the previous iteration, as the prior knowledge for the next iteration, will cause changes in the total field, which provides additional information outside the Ewald sphere and thereby gives rise to super-resolution. Comprehensive numerical examples are used to verify these viewpoints.

3.
Opt Express ; 30(14): 24544-24552, 2022 Jul 04.
Artigo em Inglês | MEDLINE | ID: mdl-36237006

RESUMO

The calculation method for light emission efficiency splits external quantum efficiency (EQE) into internal quantum efficiency (IQE) and light extraction efficiency (LEE) independently. Consequently, the IQE connected to Purcell factor and the LEE are calculated separately. This traditional method ignores the interplays between the Purcell factor and transmittance coefficient in spectral domain, which all strongly depend on emitting directions. In this work, we propose a new figure of merit to describe the light emission process accurately by using the direction-dependent Purcell factor and transmittance coefficient simultaneously. We use a specific LED structure as a numerical example to illustrate the calculation method and optimization procedure.

4.
Cell Mol Biol (Noisy-le-grand) ; 66(3): 48-51, 2020 Jun 05.
Artigo em Inglês | MEDLINE | ID: mdl-32538746

RESUMO

Alpha-fetoprotein (AFP) is a protein encoded by the AFP gene and normally produced by the fetus. The purpose of this study is to investigate the efficacy of lobaplatin in combination with 5-fluorouracil (5-FU) and doxorubicin on AFP and treatment of primary carcinoma of the liver by transhepatic arterial chemotherapy and embolization (TACE). Patients with primary carcinoma of the liver who took the TACE for treatment were enrolled in this study and divided randomly into the research group and the control group. Patients in the research group adopted the TACE in combination with lobaplatin, while those in the control group took cisplatin instead in combination with TACE. We compared the baseline data, hepatic indicators before treatment and after 1 month of treatment, efficacy and the incidence rates of adverse events after TACE between two groups. Differences in the baseline data, including Child-pugh grade, type of liver cirrhosis, KPS scores and AFP showed no statistical significance (P >0.05). Before the treatment, we identified no significant differences in the comparison of ALT, AST, TBiL and ALB between two groups (P >0.05), while significant differences emerged after treatment (P <0.05). Also, efficacy comparison revealed the significant difference between the two groups (P <0.05). After TACE, patients in the research group reported 1 case of nausea, 1 of vomiting and 1 of necrotic absorption fever, and those in the control group reported 3 cases of nausea, 5 of vomiting and 4 of necrotic absorption fever, with a significant difference in comparison of the incidence rates (P <0.05). TACE is a promising strategy for the treatment of primary carcinoma of the liver, while lobaplatin, as the 3rd generation of anti-tumor platinum-based drugs, is less toxic than cisplatin, but excels in efficacy.


Assuntos
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Quimioembolização Terapêutica , Ciclobutanos/uso terapêutico , Doxorrubicina/uso terapêutico , Fluoruracila/uso terapêutico , Neoplasias Hepáticas/tratamento farmacológico , Compostos Organoplatínicos/uso terapêutico , alfa-Fetoproteínas/metabolismo , Protocolos de Quimioterapia Combinada Antineoplásica/farmacologia , Quimioembolização Terapêutica/efeitos adversos , Ciclobutanos/farmacologia , Doxorrubicina/farmacologia , Feminino , Fluoruracila/farmacologia , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Compostos Organoplatínicos/farmacologia , Resultado do Tratamento
5.
Opt Express ; 23(3): 2798-807, 2015 Feb 09.
Artigo em Inglês | MEDLINE | ID: mdl-25836140

RESUMO

Study of photon decay rate is essential to various optical devices, where graphene is an emerging building block due to its electrical tunability. In this paper, we study photon decay rate of a quantum emitter near a metallic split-ring resonator, which is embedded in a multilayered substrate incorporating a graphene layer. Analyzing photon decay rate in such a complex multilayered system is not only computationally challenging but also highly important to experimentally realizable devices. First, the dispersion relation of graphene plasmonics supported at a dieletric/graphene/dielectric structure is investigated systematically. Meanwhile, the dispersion relation of metallic plasmonics supported at a dielectric/metal structure is studied comparatively. According to our investigation, graphene offers several flexible tuning routes for manipulating photon decay rate, including tunable chemical potential and the emitter's position and polarization. Next, considering plasmonic waves in a graphene sheet occur in the infrared regime, we carefully design a metallic split ring resonating around the same frequency range. Consequently, this design enables a mutual interaction between graphene plasmonics and metallic plasmonics. The boundary element method with a multilayered medium Green's function is adopted in the numerical simulation. Blue-shifted and splitting resonance peaks are theoretically observed, which suggests a strong mode coupling. Moreover, the mode coupling has a switch on-off feature via electrostatically doping the graphene sheet. This work is helpful to dynamically manipulate photon decay rate in complex optical devices.

6.
Opt Express ; 20(18): 20210-21, 2012 Aug 27.
Artigo em Inglês | MEDLINE | ID: mdl-23037073

RESUMO

A rigorous surface integral equation approach is proposed to study the spontaneous emission of a quantum emitter embedded in a multilayered plasmonic structure with the presence of arbitrarily shaped metallic nanoscatterers. With the aid of the Fermi's golden rule, the spontaneous emission of the emitter can be calculated from the local density of states, which can be further expressed by the imaginary part of the dyadic Green's function of the whole electromagnetic system. To obtain this Green's function numerically, a surface integral equation is established taking into account the scattering from the metallic nanoscatterers. Particularly, the modeling of the planar multilayered structure is simplified by applying the layered medium Green's function to reduce the computational domain and hence the memory requirement. Regarding the evaluation of Sommerfeld integrals in the layered medium Green's function, the discrete complex image method is adopted to accelerate the evaluation process. This work offers an accurate and efficient simulation tool for analyzing complex multilayered plasmonic system, which is commonly encountered in the design of optical elements and devices.


Assuntos
Algoritmos , Modelos Teóricos , Ressonância de Plasmônio de Superfície , Simulação por Computador , Luz , Espalhamento de Radiação
7.
Opt Express ; 19(17): 15908-18, 2011 Aug 15.
Artigo em Inglês | MEDLINE | ID: mdl-21934954

RESUMO

We propose a novel optical design of organic solar cell with a hybrid plasmonic system, which comprises a plasmonic cavity coupled with a dielectric core-metal shell nanosphere. From a rigorous solution of Maxwell's equations, called volume integral equation method, optical absorption of the active polymer material has a four-fold increase. The significant enhancement mainly attributes to the coupling of symmetric surface wave modes supported by the cavity resonator. The dispersion relation of the plasmonic cavity is characterized by solving an 1D eigenvalue problem of the air/metal/polymer/metal/air structure with finite thicknesses of metal layers. We demonstrate that the optical enhancement strongly depends on the decay length of surface plasmon waves penetrated into the active material. Furthermore, the coherent interplay between the cavity and the dielectric core-metal shell nanosphere is undoubtedly confirmed by our theoretical model. The work offers detailed physical explanations to the hybrid plasmonic cavity device structure for enhancing the optical absorption of organic photovoltaics.

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