[The role of bisphosphonate in the treatment of bone metastases from prostate cancer]. / Apport des bisphosphonates dans la prise en charge des métastases osseuses du cancer de la prostate.

BACKGROUND: Bone metastasis is very frequent in prostate cancer. It is a turning point that marks the severity of the disease. Before metastasis become symptomatic, treatment preventing bone events should be indicated. AIM: To evaluate the role of bisphosphonate in the treatment of bone metastases from prostate cancer. METHODS: A review of literature. RESULTS: Bisphosphonates play a very important role to prevent bone mass loss and to reduce bone complication events. CONCLUSION: Bisphosphonates are recommended as preventive treatment at the time of diagnosis of bone metastatic prostate cancer.

[Bellini renal cell carcinoma : diagnosis and treatment. A report of 7 cases]. / Carcinome à cellules rénales de Bellini : diagnostic et traitement A propos de 7 cas.

BACKGROUND: The Bellini collecting duct carcinoma (CDC) is a very rare form of renal cell carcinoma (1%) associated with an extremely poor prognosis. AIM: To study clinical and radiological characteristics of CDC. METHODS: From 1993 to 2002, 7 patients with CDC were treated at our institution. The diagnosis of CDC was made by a nephrectomy specimen in all cases. Demographic, clinical, pathological and survival data were gathered. RESULTS: They were five men and two women with an average age of 63 years. Lumbar pain and hematuria were the main symptoms. At presentation 2 T1N0M0, 1 T2N0M0, 1 T3N0M0, 1 T3N+M0 and 2 T4N+M+ tumors were seen. All patients underwent a radical nephrectomy. The two patients who had TNM stage I disease survived without evidence of disease at 5 years and 11 years respectively. Patients with a T4N+M+ tumor experienced rapid progression and died respectively at 3 and 5 months after nephretomy. The 3 other patients with T3N+M0, T3N0M0 and T2N0M0 disease; respectively; progressed rapidly and were lost to follow-up after one year. CONCLUSION: CDC is an aggressive variety of kidney neoplasm that is often associated with nodal and visceral metastases at presentation.It is associated with poor prognosis. For the majority of patients surgical treatment will not result in a cure. Early detection may be the best method for prolonging patient survival.

[Eosinophilic cystitis: review of nine cases]. / La cystite à éosinophiles pseudo-tumorale: a propos de neuf nouvelles observations.

BACKGROUND: Eosinophilic cystitis is a rare inflammatory pathology. It remains a poorly understood entity. AIM: To report a series of adult cases of eosinophilic cystitis mimicking a bladder tumor. METHODS: Retrospective study of cases of eosinophilic cystitis collected in an urology department. RESULTS: Diagnosis was established on a spontaneous bladder perforation in one case and on hematuria in the eight other cases. Histopatholgy studies confirmed the diagnosis. Eight patients underwent an endoscopic resection of bladder lesions followed by medical therapy with nonsteroidal anti-inflammatory drugs and cortimoxazole. An ileal bladder enlargement was performed in one case. Regular follow-up didn't reveal any recurrence. CONCLUSION: Eosinophilic cystitis is a rare disease simulating a tumor of bladder. Its clinical presentation is not specific and final diagnosis is based on pathology. Endoscopic resection will help to pathologic diagnosis. Associated to corticoids and antihistaminic drug endoscopic resection constitute the treatment of choice.

[Adult's cryptorchidism: clinical and therapeutic aspects. About 100 cases]. / La cryptorchidie de l'adulte: aspects cliniques et thérapeutiques. A propos de 100 cas.

BACKGROUND: Cryptorchidism is a pathological condition defined as the failure of the testis descending into the scrotum. It is a rare condition in adults. AIM: To study clinical and therapeutic aspects of cryptorchidism in adults. METHODS: A retrospective study of a series of 100 adult patients (mean age: 25.1 years; 19-50 years) with cryptorchid testis admitted in an urology department in Tunis. RESULTS: The main reasons for consultation were the finding of an empty purse, inguinal pain and primary sterility. The testicle was palpable in 84 cases. The treatment consisted of an orchidopexy in most cases and in 14 cases orchydectomy. CONCLUSION: Finding of cryptorchidism in adult is a real diagnostic failure. Surgical treatment is indicated to facilitate surveillance.

[Overview of premature and retarded ejaculation]. / Éjaculation prématurée et retardée.

Frequently met in clinical sexology as in general medicine, ejaculatory troubles had a multifactorial etiopathogeny and are subjects to controversies. Their therapies remain difficult despite different possible approaches.

Circumcaval ureter with a synchronous ipsilateral transitional cell carcinoma of the upper urinary tract and the urinary bladder.

AIM: We report a case of concomitant ureteral transitional cell carcinoma (TCC) developed in a circumcaval ureter associated to an invasive bladder cancer. CASE: Diagnosis was made by intravenous urography (IVU) and contrast-enhanced computed tomography (CT) scanner which showed a typical 'J' shaped deformity in the dilated proximal ureteric segment with moderate right hydronephrosis and pelvic filling defect associated to bladder filling defect due to a bladder tumor. The patient underwent a radical cystoprostatectomy and nephroureterectomy; no recurrence was detected after a 12 months period of follow-up.