1.
Chembiochem
; 13(18): 2665-70, 2012 Dec 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23143740
RESUMO
Sweet relief: the Parkinson's disease- associated protein α-synuclein is post-translationally modified by N-acetylglucosamine (O-GlcNAc), but the biochemical consequences are unknown. Here we show that an O-GlcNAc-modified peptide does not participate in α-synuclein aggregation, thus suggesting that O-GlcNAc might directly inhibit aggregation in cells.