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1.
Materials (Basel) ; 11(7)2018 Jul 20.
Artigo em Inglês | MEDLINE | ID: mdl-30037020

RESUMO

Local corrosion damage of steel structures can occur due to damage to the paint-coated surface of structures. Such damage can affect the structural behavior and performance of steel structures. Compressive loading tests were, thus, carried out in this study to examine the effect of local corrosion damage on the structural behavior and strength of tubular members. Artificial cross-sectional damage on the surface of the tubular members was introduced to reflect the actual corroded damage under exposure to a corrosion environment. The compressive failure modes and compressive strengths of the tubular members were compared according to the localized cross-sectional damage. The compressive loading test results showed that the compressive strengths were affected by the damaged width within a certain range. In addition, finite element analysis (FEA) was conducted with various parameters to determine the effects of the damage on the failure mode and compressive strength of the stub column. From the FEA results, the compressive strength was decreased proportionally with the equivalent cross-sectional area ratio and damaged volume ratio.

2.
Osong Public Health Res Perspect ; 5(6): 378-82, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-25562048

RESUMO

Current Ebola virus outbreak in West Africa already reached the total number of 1,323 including 729 deaths by July 31st. the fatality is around 55% in the southeastern area of Guinea, Sierra Leone, Liberia, and Nigeria. The number of patients with Ebola Hemorrhagic Fever (EHF) was continuously increasing even though the any effective therapeutics or vaccines has not been developed yet. The Ebola virus in Guinea showed 98% homology with Zaire Ebola Virus. Study of the pathogenesis of Ebola virus infection and assess of the various candidates of vaccine have been tried for a long time, especially in United States and some European countries. Even though the attenuated live vaccine and DNA vaccine containing Ebola viral genes were tested and showed efficacy in chimpanzees, those candidates still need clinical tests requiring much longer time than the preclinical development to be approved for the practical treatment. It can be expected to eradicate Ebola virus by a safe and efficient vaccine development similar to the case of smallpox virus which was extinguished from the world by the variola vaccine.

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