Real-life effect on the control of risk factors associated with initiation of the cardiovascular polypill created from equipotent drugs.

OBJECTIVE: This work aims to analyze the impact of Spain's National Center for Cardiovascular Research (CNIC-Ferrer)'s cardiovascular (CV)-polypill on blood pressure (BP) and low-density lipoprotein cholesterol (cLDL) levels in patients in our healthcare area who previously took equipotent doses of statins and antihypertensives. MATERIAL AND METHODS: All patients in our healthcare area (Santiago de Compostela, Spain) who, as of December 31, 2019, had an active prescription for the CV-polypill (CNIC-Ferrer) since January 16, 2015 were registered. The index date was the start date of the CV-polypill prescription. The drugs the patient had previously received for dyslipidemia and hypertension were analyzed, classifying them by their equivalent potency to atorvastatin and ramipril. Changes in cLDL and BP were analyzed by means of Student's t-test for paired samples. RESULTS: We analyzed 547 patients with a mean age of 71.5 ± 11.5 years. The majority were men (60.6%). We observed a decrease in cLDL (-10.6 [95% CI: -7.0, -14.3], p < 0.001) in patients who started taking the CV-polypill who had previously taken equally potent doses of atorvastatin (n = 471). We documented a reduction in systolic BP (-3.7 [95% CI: -0.4, -6.9], p = 0.029) in patients who had previously taken equally potent doses of ramipril (n = 360). In 88 patients, the CV-polypill was started via equally potent doses of atorvastatin and ramipril, with a decrease in cLDL (-8.7 [95% CI: -3.8, -13.6], p = 0.001) and systolic BP (-3.6 [95% CI: -7.8, 0.5], p = 0.085). CONCLUSIONS: The initiation of treatment with the CV-polypill in patients who previously received equally potent treatment with atorvastatin and ramipril was associated with a greater reduction in cLDL and systolic BP.

[Knowledge And Experience In Gender Violence Of Tutors And Trainees Of Galicia Family Medicine]. / Conocimiento y experiencia en violencia de género de las/os tutoras/es médicas/os y residentes de medicina de familia de Galicia.

OBJECTIVE: To analyse the level of preparation, knowledge and experience of gender violence of medical tutors and family medicine trainees of the Teaching Units of Family and Community Care of Galicia. METHODS: Descriptive cross-sectional study conducted in the 7 Teaching Units of Family and Community Care in Galicia. The Physician Readiness Manage Intimate Violence Survey (PREMIS), in its validated version in Spanish was used. This survey allows the collection of information from primary health care professionals about their attitudes, knowledge, and practices as regards gender violence. A descriptive and comparative statistical analysis was performed on the data. RESULTS: Out of a total of 159 questionnaires received, 72.32% came from women, and 59.1% of the responses were from doctors / tutors. It was noted that there were statistically significant differences in the detection / diagnosis of violence by those professionals who were aware of the gender violence protocol or who had received training in this area (P<.01). In the self-perception of gender violence training, statistically significant worse results were observed in those professionals with greater care burden (P<.05). CONCLUSIONS: Having received training or knowing the health care protocol on gender violence is associated with greater detection of cases of gender violence. There has been a deficit in training in gender-based violence both in tutors and in family medicine residents, especially in those with greater care burden, so it is a priority to develop medical training strategies in this field.