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1.
Am J Emerg Med ; 35(11): 1630-1635, 2017 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-28511807

RESUMO

OBJECTIVE: Prehospital personnel who lack advanced airway management training must rely on basic techniques when transporting unconscious trauma patients. The supine position is associated with a loss of airway patency when compared to lateral recumbent positions. Thus, an inherent conflict exists between securing an open airway using the recovery position and maintaining spinal immobilization in the supine position. The lateral trauma position is a novel technique that aims to combine airway management with spinal precautions. The objective of this study was to compare the spinal motion allowed by the novel lateral trauma position and the well-established log-roll maneuver. METHODS: Using a full-body cadaver model with an induced globally unstable cervical spine (C5-C6) lesion, we investigated the mean range of motion (ROM) produced at the site of the injury in six dimensions by performing the two maneuvers using an electromagnetic tracking device. RESULTS: Compared to the log-roll maneuver, the lateral trauma position caused similar mean ROM in five of the six dimensions. Only medial/lateral linear motion was significantly greater in the lateral trauma position (1.4mm (95% confidence interval [CI] 0.4, 2.4mm)). CONCLUSIONS: In this cadaver study, the novel lateral trauma position and the well-established log-roll maneuver resulted in comparable amounts of motion in an unstable cervical spine injury model. We suggest that the lateral trauma position may be considered for unconscious non-intubated trauma patients.


Assuntos
Vértebras Cervicais/lesões , Lesões do Pescoço/terapia , Posicionamento do Paciente/métodos , Amplitude de Movimento Articular , Traumatismos da Coluna Vertebral/terapia , Idoso , Idoso de 80 Anos ou mais , Manuseio das Vias Aéreas/métodos , Fenômenos Biomecânicos , Cadáver , Estudos Cross-Over , Serviços Médicos de Emergência/métodos , Feminino , Humanos , Disco Intervertebral/lesões , Ligamento Amarelo/lesões , Ligamentos Longitudinais/lesões , Masculino , Pessoa de Meia-Idade , Medula Espinal , Fraturas da Coluna Vertebral , Decúbito Dorsal
2.
Am J Vet Res ; 78(6): 712-717, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28541152

RESUMO

OBJECTIVE To compare stiffness and resistance to cyclic fatigue of two 3.5-mm locking system plate-rod constructs applied to an experimentally created fracture gap in femurs of canine cadavers. SAMPLE 20 femurs from cadavers of 10 mixed-breed adult dogs. PROCEDURES 1 femur from each cadaver was stabilized with a conical coupling plating system-rod construct, and the contralateral femur was stabilized with a locking compression plate (LCP)-rod construct. An intramedullary Steinmann pin was inserted in each femur. A 40-mm gap then was created; the gap was centered beneath the central portion of each plate. Cyclic axial loading with increasing loads was performed. Specimens that did not fail during cyclic loading were subjected to an acute load to failure. RESULTS During cyclic loading, significantly more LCP constructs failed (6/10), compared with the number of conical coupling plating system constructs that failed (1/10). Mode of failure of the constructs included fracture of the medial or caudal aspect of the cortex of the proximal segment with bending of the plate and pin, bending of the plate and pin without fracture, and screw pullout. Mean stiffness, yield load, and load to failure were not significantly different between the 2 methods of stabilization. CONCLUSIONS AND CLINICAL RELEVANCE Both constructs had similar biomechanical properties, but the conical coupling plating system was less likely to fail than was the LCP system when subjected to cyclic loading. These results should be interpreted with caution because testing was limited to a single loading mode.


Assuntos
Placas Ósseas/veterinária , Cães/lesões , Fraturas do Fêmur/veterinária , Fixação Interna de Fraturas/veterinária , Animais , Fenômenos Biomecânicos , Parafusos Ósseos/veterinária , Cadáver , Cães/cirurgia , Fraturas do Fêmur/cirurgia , Fêmur/cirurgia
3.
Gait Posture ; 53: 35-40, 2017 03.
Artigo em Inglês | MEDLINE | ID: mdl-28073085

RESUMO

Despite the ubiquity of gait assessment in clinic and research, it is unclear how observation impacts gait, particularly in persons with chronic pain and psychological stress. We compared temporal spatial gait patterns in people with and without chronic low back pain (CLBP) when they were aware and unaware of being observed. This was a repeated-measures, deception study in 55 healthy persons (32.0±12.4 yr, 24.2±2.7kg/m2) and persons with CLBP (51.9±17.9 yr, 27.8±4.4kg/m2). Participants performed one condition in which they were unaware of observation (UNW), and three conditions under investigator observation: (1) aware of observation (AWA), (2) investigators watching cadence, (3) investigators watching step length. Participants walked across an 8.4m gait mat, while temporal spatial parameters of gait were collected. The Medical Outcomes Short Form (SF-12), Beck Depression Inventory (BDI), State Trait Anxiety Inventory (STAI), and Oswestry Disability Index (ODI) were completed. Significant condition by group interactions were found for velocity and step length (p<0.05). Main effects of study condition existed for all gait variables except for step width. Main effects of group (healthy, LBP) were significant for all variables except for step width (p<0.05). Regression analyses revealed that after accounting for age, sex, and SF-12 mental component score, BDI scores predict velocity changes during walking from the UNW to AWA conditions. These findings show that people change their gait patterns when being observed. Gait analyses may require additional trials before data can reliably be interpreted and used for clinical decision-making.


Assuntos
Marcha , Dor Lombar/fisiopatologia , Caminhada , Adulto , Análise de Variância , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Variações Dependentes do Observador , Medição da Dor , Índice de Gravidade de Doença
4.
Orthop J Sports Med ; 3(9): 2325967115601853, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-26535397

RESUMO

BACKGROUND: Numerous studies have shown that there are better alternatives to log rolling patients with unstable spinal injuries, although this method is still commonly used for placing patients onto a spine board. No previous studies have examined transfer maneuvers involving an injured football player with equipment in place onto a spine board. PURPOSE: To test 3 different transfer maneuvers of an injured football player onto a spine board to determine which method most effectively minimizes spinal motion in an injured cervical spine model. STUDY DESIGN: Controlled laboratory study. METHODS: Five whole, lightly embalmed cadavers were fitted with shoulder pads and helmets and tested both before and after global instability was surgically created at C5-C6. An electromagnetic motion analysis device was used to assess the amount of angular and linear motion with sensors placed above and below the injured segment during transfer. Spine-boarding techniques evaluated were the log roll, the lift and slide, and the 8-person lift. RESULTS: The 8-person lift technique resulted in the least amount of angular and linear motion for all planes tested as compared with the lift-and-slide and log-roll techniques. This reached statistical significance for lateral bending (P = .031) and medial-lateral translation (P = .030) when compared with the log-roll maneuver. The lift-and-slide technique was significantly more effective at reducing motion than the log roll for axial rotation (P = .029) and lateral bending (P = .006). CONCLUSION: The log roll resulted in the most motion at an unstable cervical injury as compared with the other 2 spine-boarding techniques examined. The 8-person lift and lift-and-slide techniques may both be more effective than the log roll at reducing unwanted cervical spine motion when spine boarding an injured football player. Reduction of such motion is critical in the prevention of iatrogenic injury.

5.
J Orthop Res ; 33(11): 1603-10, 2015 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-25982776

RESUMO

The canine knee is morphologically similar to the human knee and thus dogs have been used in experimental models to study human knee pathology. To date, there is limited data of normal canine 3D knee kinematics during daily activities. The objective of this study was to characterize 3D in-vivo femorotibial kinematics in normal dogs during commonly performed daily activities. Using single-plane fluoroscopy, six normal dogs were imaged performing walk, trot, sit, and stair ascent activities. CT-generated bone models were used for kinematic measurement using a 3D-to-2D model registration technique. Increasing knee flexion angle was typically associated with increasing tibial internal rotation, abduction and anterior translation during all four activities. The precise relationship between flexion angle and these movements varied both within and between activities. Significant differences in axial rotation and coronal angulation were found at the same flexion angle during different phases of the walk and trot. This was also found with anterior tibial translation during the trot only. Normal canine knees accommodate motion in all planes; precise kinematics within this envelope of motion are activity dependent. This data establishes the characteristics of normal 3D femorotibial joint kinematics in dogs that can be used as a comparison for future studies.


Assuntos
Cães/fisiologia , Articulações/fisiologia , Joelho de Quadrúpedes/fisiologia , Animais , Artrografia , Fenômenos Biomecânicos , Fluoroscopia , Imageamento Tridimensional , Valores de Referência , Joelho de Quadrúpedes/diagnóstico por imagem , Tomografia Computadorizada por Raios X
6.
J Orthop ; 12(2): 92-6, 2015 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-25972700

RESUMO

PURPOSE: This pilot study tested whether FiberWire provides similar protection to steel wire against repair displacement in patella fractures. METHODS: Thirteen cadaver knees were cyclically loaded with 10 cycles (0-90° flexion) and fracture displacement was recorded. Fixation methods were also tested in load to failure (>3 mm displacement). RESULTS: There was no difference between wire types in fracture displacement (1.4 mm ± 0.33 mm vs 1.2 mm ± 0.34 mm, respectively; p = 0.418) or in the load to failure (714.7 N ± 110.9 N vs 744.5 N ± 92.8 N, respectively; p = 0.360). CONCLUSION: FiberWire provides similar protection to steel wire against repair displacement after fixation of patellar fractures.

7.
PM R ; 7(1): 26-33, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-24998402

RESUMO

OBJECTIVE: To examine whether runners recovering from a lower body musculoskeletal injury have different metabolic, cardiopulmonary, and gait responses compared with healthy runners. DESIGN: Cross-sectional study. SETTING: Research laboratory at an academic institution. METHODS: Healthy runners (n = 50) were compared with runners who were recently injured but had returned to running (n = 50). Both groups were participating in similar cross-training modalities such as swimming, weight training, biking, and yoga. Running gait was analyzed on a treadmill using 3-dimensional motion capture, and metabolic and cardiopulmonary measures were captured simultaneously with a portable metabolic analyzer. MAIN OUTCOME MEASURES: Rate of oxygen consumption, heart rate, ventilation, carbohydrate and fat oxidation values, gait temporospatial parameters and range of motion measures (ROM) in the sagittal plane, energy expenditure, and vertical displacement of the body's center of gravity (COG). RESULTS: The self-selected running speed was different between the injured and healthy runners (9.7 ± 1.1 km/h and 10.6 ± 1.1 km/h, respectively; P = .038). No significant group differences were noted in any metabolic or cardiopulmonary variable while running at the self-selected or standard speed (13.6 km/h). The vertical displacement of the COG was less in the injured group (8.4 ± 1.4 cm and 8.9 ± 1.4, respectively; P = .044). ROM about the right ankle in the sagittal plane at the self-selected running speed during the gait cycle was less in the injured runners compared with the healthy runners (P < .05). CONCLUSIONS: Runners with a recent lower body injury who have returned to running have similar cardiopulmonary and metabolic responses to running as healthy runners at the self-selected and standard speeds; this finding may be due in part to participation in cross-training modes that preserve cardiopulmonary and metabolic adaptations. Injured runners may conserve motion by minimizing COG displacement and ankle joint ROM during a gait cycle.


Assuntos
Traumatismos em Atletas/metabolismo , Metabolismo Energético/fisiologia , Marcha/fisiologia , Consumo de Oxigênio , Amplitude de Movimento Articular/fisiologia , Corrida/lesões , Adolescente , Adulto , Idoso , Traumatismos em Atletas/fisiopatologia , Fenômenos Biomecânicos , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem
8.
Prehosp Emerg Care ; 18(4): 539-43, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24878332

RESUMO

STUDY OBJECTIVE: To compare the amount of segmental vertebral motion produced with the lateral recovery position and the HAINES technique when performed on cadavers with destabilized cervical spines. METHODS: The cervical spines of 10 cadavers were surgically destabilized at the C5-C6 vertebral segment. Sensors from an electromagnetic tracking device were affixed to the vertebrae in question to monitor the amount of anterior/posterior, medial/lateral, and distraction/compression linear motion produced during the application of the two study techniques. RESULTS: The statistical analysis of linear motion data did not reveal any significant differences between the two recovery positions. CONCLUSION: At this time, no single version of the recovery position can be endorsed for the spine-injured trauma patient. More research is needed to fully ascertain the safety of commonly used recovery positions.


Assuntos
Vértebras Cervicais/lesões , Imobilização , Amplitude de Movimento Articular/fisiologia , Traumatismos da Coluna Vertebral/fisiopatologia , Transporte de Pacientes/métodos , Idoso , Idoso de 80 Anos ou mais , Cadáver , Feminino , Humanos , Imobilização/métodos , Masculino , Postura , Medição de Risco
9.
Am J Vet Res ; 75(5): 477-85, 2014 May.
Artigo em Inglês | MEDLINE | ID: mdl-24762020

RESUMO

OBJECTIVE: To compare accuracy of a noninvasive single-plane fluoroscopic technique with radiostereometric analysis (RSA) for determining 3-D femorotibial poses in a canine cadaver with normal stifle joints. SAMPLE: Right pelvic limb from a 25-kg adult mixed-breed dog. PROCEDURES: A CT scan of the limb was obtained before and after metal beads were implanted into the right femur and tibia. Orthogonal fluoroscopic images of the right stifle joint were acquired to simulate a biplanar fluoroscopic acquisition setup. Images were obtained at 5 flexion angles from 110° to 150° to simulate a gait cycle; 5 cycles were completed. Joint poses were calculated from the biplanar images by use of RSA with CT-derived beaded bone models and compared with measurements obtained by use of CT-derived nonbeaded bone models matched to single-plane, lateral-view fluoroscopic images. Single-plane measurements were performed by 2 observers and repeated 3 times by the primary observer. RESULTS: Mean absolute differences between the single-plane fluoroscopic analysis and RSA measurements were 0.60, 1.28, and 0.64 mm for craniocaudal, proximodistal, and mediolateral translations, respectively, and 0.63°, 1.49°, and 1.58° for flexion-extension, abduction-adduction, and internal-external rotations, respectively. Intra- and interobserver repeatability was strong with maximum mean translational and rotational SDs of 0.52 mm and 1.36°, respectively. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggested that single-plane fluoroscopic analysis performed by use of CT-derived bone models is a valid, noninvasive technique for accurately measuring 3-D femorotibial poses in dogs.


Assuntos
Precisão da Medição Dimensional , Fluoroscopia/veterinária , Imageamento Tridimensional/veterinária , Joelho de Quadrúpedes/diagnóstico por imagem , Animais , Fenômenos Biomecânicos , Cadáver , Cães , Fêmur/diagnóstico por imagem , Fluoroscopia/métodos , Marcha/fisiologia , Imageamento Tridimensional/métodos , Amplitude de Movimento Articular/fisiologia , Tíbia/diagnóstico por imagem , Tomografia Computadorizada por Raios X/veterinária
10.
Am J Vet Res ; 75(5): 486-93, 2014 May.
Artigo em Inglês | MEDLINE | ID: mdl-24762021

RESUMO

OBJECTIVE: To compare accuracy of a noninvasive single-plane fluoroscopic analysis technique with radiostereometric analysis (RSA) for determining 3-D femorotibial poses in a canine cadaver stifle joint treated by tibial-plateau-leveling osteotomy (TPLO). SAMPLE: Left pelvic limb from a 25-kg adult mixed-breed dog. PROCEDURES: A CT scan of the left pelvic limb was performed. The left cranial cruciate ligament was transected, and a TPLO was performed. Radiopaque beads were implanted into the left femur and tibia, and the CT scan was repeated. Orthogonal fluoroscopic images of the left stifle joint were acquired at 5 stifle joint flexion angles ranging from 110° to 150° to simulate a gait cycle; 5 gait cycles were completed. Joint poses were calculated from the biplanar images by use of a digitally modified RSA and were compared with measurements obtained by use of hybrid implant-bone models matched to lateral-view fluoroscopic images. Single-plane measurements were performed by 2 observers and repeated 3 times by the primary observer. RESULTS: Mean absolute differences between results of the single-plane fluoroscopic analysis and modified RSA were 0.34, 1.05, and 0.48 mm for craniocaudal, proximodistal, and mediolateral translations, respectively, and 0.56°, 0.85°, and 1.08° for flexion-extension, abduction-adduction, and internal-external rotations, respectively. Intraobserver and interobserver mean SDs did not exceed 0.59 mm for all translations and 0.93° for all rotations. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggested that single-plane fluoroscopic analysis by use of hybrid implant-bone models may be a valid, noninvasive technique for accurately measuring 3-D femorotibial poses in dogs treated with TPLO.


Assuntos
Precisão da Medição Dimensional , Osteotomia/veterinária , Joelho de Quadrúpedes/diagnóstico por imagem , Tíbia/cirurgia , Animais , Ligamento Cruzado Anterior/cirurgia , Fenômenos Biomecânicos , Cadáver , Cães , Fêmur/cirurgia , Fluoroscopia/veterinária , Marcha/fisiologia , Masculino , Osteotomia/métodos , Análise Radioestereométrica/veterinária , Amplitude de Movimento Articular/fisiologia , Joelho de Quadrúpedes/cirurgia , Tomografia Computadorizada por Raios X/veterinária
11.
Vet Surg ; 43(1): 58-65, 2014 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-24527494

RESUMO

OBJECTIVE: To compare biomechanical properties of (1) 4.5 mm cortical screws and Fitz Fenestrated Tubular Transcondylar (F2T2) screws; (2) normal humeri and humeri with an intracondylar osteotomy; and (3) humeri with an intracondylar osteotomy stabilized with either a 4.5 mm cortical screw or a F2T2 screw. STUDY DESIGN: Cadaveric biomechanical assessment. SAMPLE POPULATION: 4.5 mm cortical screws (n = 10), 5.85 mm F2T2 screws (n = 10), and paired dog humeri (n = 40). METHODS: Cortical and F2T2 screws were loaded to failure in 3-point bending. Ten pairs of humeri with or without an intracondylar osteotomy were axially loaded to failure. Ten additional pairs of humeri with an intracondylar osteotomy were alternately stabilized with a positional cortical or F2T2 screw and axially loaded to failure. RESULTS: Mean stiffness, yield load, and failure load was significantly greater (P < .001) for the F2T2 screws compared with cortical screws as well as for intact humeri compared with humeri with an intracondylar osteotomy (P < .001). There were no significant differences in mean stiffness (P = .59), yield load (P = .31), or failure load (P = .24) between humeri with stabilized intracondylar osteotomy. CONCLUSION: Isolated F2T2 screws have superior mechanical properties to 4.5 mm cortical screws when loaded in 3-point bending. Intracondylar osteotomy adversely affected humeral mechanical integrity. Osteotomized humeri stabilized by either screw had comparable mechanical properties.


Assuntos
Parafusos Ósseos/veterinária , Cães/cirurgia , Úmero/cirurgia , Osteotomia/veterinária , Animais , Fenômenos Biomecânicos , Osteogênese , Osteotomia/instrumentação , Suporte de Carga
12.
J Neurotrauma ; 31(9): 834-45, 2014 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-24378197

RESUMO

Androgen administration protects against musculoskeletal deficits in models of sex-steroid deficiency and injury/disuse. It remains unknown, however, whether testosterone prevents bone loss accompanying spinal cord injury (SCI), a condition that results in a near universal occurrence of osteoporosis. Our primary purpose was to determine whether testosterone-enanthate (TE) attenuates hindlimb bone loss in a rodent moderate/severe contusion SCI model. Forty (n=10/group), 14 week old male Sprague-Dawley rats were randomized to receive: (1) Sham surgery (T9 laminectomy), (2) moderate/severe (250 kdyne) SCI, (3) SCI+Low-dose TE (2.0 mg/week), or (4) SCI+High-dose TE (7.0 mg/week). Twenty-one days post-injury, SCI animals exhibited a 77-85% reduction in hindlimb cancellous bone volume at the distal femur (measured via µCT) and proximal tibia (measured via histomorphometry), characterized by a >70% reduction in trabecular number, 13-27% reduction in trabecular thickness, and increased trabecular separation. A 57% reduction in cancellous volumetric bone mineral density (vBMD) at the distal femur and a 20% reduction in vBMD at the femoral neck were also observed. TE dose dependently prevented hindlimb bone loss after SCI, with high-dose TE fully preserving cancellous bone structural characteristics and vBMD at all skeletal sites examined. Animals receiving SCI also exhibited a 35% reduction in hindlimb weight bearing (triceps surae) muscle mass and a 22% reduction in sublesional non-weight bearing (levator ani/bulbocavernosus [LABC]) muscle mass, and reduced prostate mass. Both TE doses fully preserved LABC mass, while only high-dose TE ameliorated hindlimb muscle losses. TE also dose dependently increased prostate mass. Our findings provide the first evidence indicating that high-dose TE fully prevents hindlimb cancellous bone loss and concomitantly ameliorates muscle loss after SCI, while low-dose TE produces much less profound musculoskeletal benefit. Testosterone-induced prostate enlargement, however, represents a potential barrier to the clinical implementation of high-dose TE as a means of preserving musculoskeletal tissue after SCI.


Assuntos
Androgênios/administração & dosagem , Osso e Ossos/efeitos dos fármacos , Músculo Esquelético/efeitos dos fármacos , Traumatismos da Medula Espinal/complicações , Testosterona/administração & dosagem , Animais , Atrofia/prevenção & controle , Densidade Óssea/efeitos dos fármacos , Osso e Ossos/patologia , Modelos Animais de Doenças , Relação Dose-Resposta a Droga , Masculino , Músculo Esquelético/patologia , Próstata/efeitos dos fármacos , Ratos , Ratos Sprague-Dawley
13.
PM R ; 6(5): 418-26, 2014 May.
Artigo em Inglês | MEDLINE | ID: mdl-24211698

RESUMO

OBJECTIVE: To compare the effects of 4 months of isolated lumbar resistance exercise and total body resistance exercise on walking performance in obese, older adults with chronic low back pain. A secondary analysis examined whether responsiveness to training modulated walking improvement. DESIGN: Randomized, controlled trial. SETTING: Research laboratory affiliated with tertiary care facility. METHODS AND INTERVENTION: Participants (N = 49; 60-85 years) were randomized into a 4-month resistance exercise intervention (TOTRX), lumbar extensor exercise intervention (LEXT), or a control group (CON). MAIN OUTCOME MEASUREMENTS: Walking performance, maximal low back strength and leg strength, and average resting and low back pain severity score (from an 11-point numerical pain rating scale; NRSpain) were collected at baseline and month 4. RESULTS: The TOTRX and LEXT improved lumbar extensor strength relative to CON, and the TOTRX (P < .05). NRSpain scores at month 4 were lowest in the TOTRX group compared with the LEXT and CON groups, respectively (2.0 ± 1.7 points vs 3.7 ± 2.6 points and 4.6 ± 2.4 points; P < .006). A total of 53% and 67% of participants in the TOTRX and LEXT groups were responders who made lumbar extensor strength gains that achieved ≥20% greater than baseline values. Although the TOTRX demonstrated the greatest improvement in walking endurance among the intervention groups, this did not reach significance (10.1 ± 12.2% improvement in TOTRX vs 7.4 ± 30.0% LEXT and -1.7 ± 17.4% CON; P = .11). Gait speed increased most in the TOTRX (9.0 ± 13.5%) compared with the LEXT and CON groups (P < .05). The change in lumbar extensor strength explained 10.6% of the variance of the regression model for the change in walking endurance (P = .024). CONCLUSIONS: The use of LEXT and TOTRX produced similar modest improvements in patients' walking endurance. Lumbar extensor strength gain compared with leg strength gain is a moderate but important contributor to walking endurance in obese older adults with chronic low back pain. Responders to resistance exercise programs (event those with only lumbar extension exercise) who make at least a 20% improvement in strength can expect better improvement in walking endurance than those who do not achieve this strength improvement.


Assuntos
Músculos do Dorso/fisiopatologia , Dor Lombar/fisiopatologia , Dor Lombar/reabilitação , Força Muscular/fisiologia , Treinamento Resistido , Caminhada/fisiologia , Idoso , Idoso de 80 Anos ou mais , Feminino , Marcha/fisiologia , Humanos , Masculino , Pessoa de Meia-Idade , Obesidade/fisiopatologia , Resistência Física/fisiologia , Análise de Regressão
14.
PLoS One ; 8(12): e81383, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-24349061

RESUMO

BACKGROUND: Transection of the canine cranial cruciate ligament (CCL) is a well-established osteoarthritis (OA) model. The effect of CCL loss on contact pressure and joint alignment has not been quantified for stifle loading in standing. The purposes of the study were to measure femorotibial contact areas and stresses and joint alignment following transection of the CCL in an ex vivo model. We hypothesized that transection of the CCL would lead to abnormal kinematics, as well as alterations in contact mechanics of the femorotibial joint. METHODOLOGY/PRINCIPAL FINDINGS: Eight canine hindlimbs were tested in a servo-hydraulic materials testing machine using a custom made femoral jig. Contact area and pressure measurements, and femorotibial rotations and translations were measured in the normal and the CCL-deficient stifle in both standing and deep flexion angles. We found that at standing angle, transection of the CCL caused cranial translation and internal rotation of the tibia with a concurrent caudal shift of the contact area, an increase in peak pressure and a decrease in contact area. These changes were not noted in deep flexion. At standing, loss of CCL caused a redistribution of the joint pressure, with the caudal region of the compartment being overloaded and the rest of the joint being underloaded. CONCLUSION: In the Pond-Nuki model alterations in joint alignment are correlated with shifting of the contact points to infrequently loaded areas of the tibial plateau. The results of this study suggest that this cadaveric Pond-Nuki model simulates the biomechanical changes previously reported in the in-vivo Pond-Nuki model.


Assuntos
Ligamento Cruzado Anterior/fisiologia , Animais , Fenômenos Biomecânicos , Cães , Osteoartrite/fisiopatologia
15.
Open Orthop J ; 7: 378-84, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-24093052

RESUMO

OBJECTIVE: This study examined the changes in synovial fluid levels of cytokines, oxidative stress and viscosity six months after intraarticular hyaluronic acid (HA) treatment in adults and elderly adults with knee osteoarthritis (OA). DESIGN: This was a prospective, repeated-measures study design in which patients with knee OA were administered 1% sodium hyaluronate. Patients (N=28) were stratified by age (adults, 50-64 years and elderly adults, ≥65 years). Ambulatory knee pain values and self-reported physical activity were collected at baseline and month six. MATERIALS AND METHODS: Knee synovial fluid aspirates were collected at baseline and at six months. Fluid samples were analyzed for pro-inflammatory cytokines (interleukins 1ß, 6,8,12, tumor necrosis factor-α, monocyte chemotactic protein), anti-inflammatory cytokines (interleukins 4, 10 13), oxidative stress (4-hydroxynonenal) and viscosity at two different physiological shear speeds 2.5Hz and 5Hz. RESULTS: HA improved ambulatory knee pain in adults and elderly groups by month six, but adults reported less knee pain-related interference with participation in exercise than elderly adults. A greater reduction in TNF-α occurred in adults compared to elderly adults (-95.8% ± 7.1% vs 19.2% ± 83.8%, respectively; p=.044). Fluid tended to improve at both shear speeds in adults compared to the elderly adults. The reduction in pain severity correlated with the change in IL-1ß levels by month six (r= -.566; p=.044). CONCLUSION: Reduction of knee pain might be due to improvements in synovial fluid viscosity and inflammation. Cartilage preservation may be dependent on how cytokine, oxidative stress profiles and viscosity change over time.

16.
Vet Surg ; 42(7): 853-9, 2013 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-24033745

RESUMO

OBJECTIVE: To (1) compare the effect of cyclic loading on craniocaudal tibial translation in cranial cruciate ligament (CrCL)-deficient stifles after extracapsular stabilization, and (2) evaluate the effect of peak force during cyclic loading on the rate of development of craniocaudal laxity. STUDY DESIGN: Biomechanical cadaveric study. SAMPLE POPULATION: Cadaveric pelvic limbs (n = 24 pairs) from skeletally mature dogs. METHODS: Twenty-four pairs of stifles were randomly assigned to 4 stabilization groups: nylon leader lateral circumfabellar-tibial suture (NLS); FiberTape lateral circumfabellar-tibial suture (FTLS); TightRope (TR); or bone anchor (BA). Contralateral limbs were cyclically loaded to produce cranial tibial translation at peak forces of either 80 or 160 N. Craniocaudal displacement of the tibia was measured with a mechanical testing machine during cyclic loading with the CrCL intact, after CrCL transection, and after extracapsular stabilization. The number of cycles each construct underwent before reaching 200% and 300% of the mean craniocaudal displacement present during cyclic loading of the CrCL-intact stifles was calculated. Number of cycles among treatment groups was compared with a Kruskal-Wallis test. P < .05 was considered significant. RESULTS: Mean ± SD translation before and after CrCL transection were 3.9 ± 0.6 and 14.6 ± 1.7 mm, respectively. TR constructs resisted significantly more cycles than NLS constructs before reaching 7.8 mm (200%) and 11.7 mm (300%) of translation when loaded to 80 N. No other differences between constructs were significant at a peak load of 80 N. All constructs reached 7.8 and 11.7 mm of translation in fewer cycles when loaded to 160 N than at 80 N. CONCLUSIONS: TR constructs were most resistant to elongation during cyclic loading. Doubling the peak force during cyclic loading significantly decreased the number of cycles constructs withstood, supporting recommendations for restricting postoperative activity after extracapsular stabilization of the CrCL-deficient stifle.


Assuntos
Cães , Procedimentos Ortopédicos/veterinária , Joelho de Quadrúpedes/cirurgia , Técnicas de Sutura/veterinária , Animais , Ligamento Cruzado Anterior/cirurgia , Fenômenos Biomecânicos , Parafusos Ósseos/veterinária , Cadáver , Procedimentos Ortopédicos/métodos , Estresse Mecânico
17.
J Athl Train ; 48(6): 797-803, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23952045

RESUMO

CONTEXT: Two methods have been proposed to transfer an individual in the prone position to a spine board. Researchers do not know which method provides the best immobilization. OBJECTIVE: To determine if motion produced in the unstable cervical spine differs between 2 prone logrolling techniques and to evaluate the effect of equipment on the motion produced during prone logrolling. DESIGN: Crossover study. SETTING: Laboratory. PATIENTS OR OTHER PARTICIPANTS: Tests were performed on 5 fresh cadavers (3 men, 2 women; age = 83 ± 8 years, mass = 61.2 ± 14.1 kg). MAIN OUTCOME MEASURE(S): Three-dimensional motions were recorded during 2 prone logroll protocols (pull, push) in cadavers with an unstable cervical spine. Three equipment conditions were evaluated: football shoulder pads and helmet, rigid cervical collar, and no equipment. The mean range of motion was calculated for each test condition. RESULTS: The pull technique produced 16% more motion than the push technique in the lateral-bending angulation direction (F1,4 = 19.922, P = .01, η(2) = 0.833). Whereas the collar-only condition and, to a lesser extent, the football-shoulder-pads-and-helmet condition demonstrated trends toward providing more stability than the no-equipment condition, we found no differences among equipment conditions. We noted an interaction between technique and equipment, with the pull maneuver performed without equipment producing more anteroposterior motion than the push maneuver in any of the equipment conditions. CONCLUSIONS: We saw a slight difference in the motion measured during the 2 prone logrolling techniques tested, with less lateral-bending and anteroposterior motion produced with the logroll push than the pull technique. Therefore, we recommend adopting the push technique as the preferred spine-boarding maneuver when a patient is found in the prone position. Researchers should continue to seek improved methods for performing prone spine-board transfers to further decrease the motion produced in the unstable spine.


Assuntos
Movimentação e Reposicionamento de Pacientes/métodos , Restrição Física/métodos , Traumatismos da Coluna Vertebral/fisiopatologia , Transporte de Pacientes/métodos , Idoso de 80 Anos ou mais , Fenômenos Biomecânicos , Cadáver , Vértebras Cervicais , Estudos Cross-Over , Feminino , Humanos , Instabilidade Articular , Masculino , Coluna Vertebral/fisiopatologia
18.
J Emerg Med ; 45(3): 366-71, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-23849357

RESUMO

BACKGROUND: As prehospital emergency rescuers prepare cervical spine-injured adult patients for immobilization and transport to hospital, it is essential that patients be placed in a favorable position. Previously, it was recommended that patients with cervical spine injuries be immobilized in a slightly flexed position using pads placed beneath the head. However, it is unknown how neck flexion created with pad placement affects the unstable spine. OBJECTIVE: To determine the effects of three different head positions on the alignment of unstable vertebral segments. METHODS: Five cadavers with a complete segmental instability at the C5 and C6 level were included in the study. The head was either placed directly on the ground (or spine board) or on foam pads. Three conditions were tested: no pad; pads 2.84 cm thick; and pads 4.26 cm thick. Pads were positioned beneath the head to determine their effect on spinal alignment. Anterior-posterior translation, flexion-extension motion, and axial displacement across the unstable segment were compared between conditions. RESULTS: Although statistical tests failed to identify any significant differences between pad conditions, some meaningful results were noted. In general, the "no pad" condition aligned the spine in a position that best replicated the intact spine. CONCLUSIONS: Because the goal of emergency rescuers is to conserve whatever physiologic or structural integrity of the spinal cord and spinal column that remains, the outcome of this study suggests that this goal may be best achieved using the "no pad" condition. However, it is recommended that more research be conducted to confirm these preliminary findings.


Assuntos
Vértebras Cervicais/lesões , Serviços Médicos de Emergência/métodos , Instabilidade Articular/prevenção & controle , Posicionamento do Paciente/métodos , Idoso , Cadáver , Feminino , Humanos , Imobilização , Masculino , Pessoa de Meia-Idade , Transporte de Pacientes , Articulação Zigapofisária/fisiopatologia
19.
Gait Posture ; 38(4): 987-92, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-23810090

RESUMO

INTRODUCTION: Spinal stenosis is defined as neurogenic claudication due to narrowing of the spinal canal lumen diameter. As the disease progresses, ambulation and gait may be impaired. Self-report measures are routinely used in the clinical setting to capture data related to lumbar pain symptoms, function and perceived disability. The associations between self-report measures and objective measures of physical function in patients with lumbar spinal stenosis are not well characterized. The purpose of this study was to determine the correlation between self-reported assessments of function with objective biomechanical measures of function. METHODS: 25 subjects were enrolled in this study. Subjects completed self-report questionnaires and biomechanical assessments of gait analysis, lumbar 3D ROM and lumbar proprioception. Correlations were determined between self-report measures and biomechanical data. RESULTS: The Oswestry Disability Index (ODI) was strongly correlated with stride length and gait velocity and weakly correlated with base of support. ODI was also weakly correlated with left lateral bending proprioception but not right lateral bending. The SF12 was not significantly correlated with any of the biomechanical measurements. Pain scores were weakly correlated with velocity, and base of support, and had no correlation any of the other biomechanical measures. DISCUSSION: There is a strong correlation between gait parameters and functional disability as measured with the ODI. Quantified gait analysis can be a useful tool to evaluate patients with lumbar spinal stenosis and to assess the outcomes of treatments on this group of patients.


Assuntos
Transtornos Neurológicos da Marcha/fisiopatologia , Dor Lombar/fisiopatologia , Vértebras Lombares , Propriocepção/fisiologia , Amplitude de Movimento Articular/fisiologia , Autorrelato , Transtornos de Sensação/fisiopatologia , Estenose Espinal/fisiopatologia , Idoso , Fenômenos Biomecânicos , Feminino , Transtornos Neurológicos da Marcha/etiologia , Humanos , Dor Lombar/etiologia , Masculino , Pessoa de Meia-Idade , Medição da Dor , Radiculopatia/etiologia , Radiculopatia/fisiopatologia , Transtornos de Sensação/etiologia , Estenose Espinal/complicações , Inquéritos e Questionários
20.
BMC Vet Res ; 9: 125, 2013 Jun 24.
Artigo em Inglês | MEDLINE | ID: mdl-23800317

RESUMO

BACKGROUND: There are several factors that can affect the fatigue life of a bone plate, including the mechanical properties of the plate and the complexity of the fracture. The position of the screws can influence construct stiffness, plate strain and cyclic fatigue of the implants. Studies have not investigated these variables in implants utilized for long bone fracture fixation in dogs and cats. The purpose of the present study was to evaluate the effect of plate working length on construct stiffness, gap motion and resistance to cyclic fatigue of dog femora with a simulated fracture gap stabilized using a 12-hole 2.4 mm locking compression plates (LCP). Femora were plated with 12-hole 2.4 mm LCP using 2 screws per fracture segment (long working length group) or with 12-hole 2.4 mm LCP using 5 screws per fracture segment (a short working length group). RESULTS: Construct stiffness did not differ significantly between stabilization techniques. Implant failure did not occur in any of the plated femora during cycling. Mean ± SD yield load at failure in the short plate working length group was significantly higher than in the long plate working length group. CONCLUSION: In a femoral fracture gap model stabilized with a 2.4 mm LCP applied in contact with the bone, plate working length had no effect on stiffness, gap motion and resistance to fatigue. The short plate working length constructs failed at higher loads; however, yield loads for both the short and long plate working length constructs were within physiologic range.


Assuntos
Placas Ósseas/veterinária , Cães/cirurgia , Fraturas do Fêmur/veterinária , Fêmur/cirurgia , Fixação Interna de Fraturas/veterinária , Animais , Placas Ósseas/normas , Fraturas do Fêmur/cirurgia , Fixação Interna de Fraturas/métodos , Distribuição Aleatória , Estresse Mecânico , Gravação em Vídeo
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