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Atomic clocks based on laser-cooled atoms have made tremendous advances in both accuracy and stability. However, advanced clocks have not found their way into widespread use because there has been little need for such high performance in real-world/commercial applications. The drive in the commercial world favours smaller, lower-power, more robust compact atomic clocks that function well in real-world non-laboratory environments. Although the high-performance atomic frequency references are useful to test Einstein's special relativity more precisely, there are not compelling scientific arguments to expect a breakdown in special relativity. On the other hand, the dynamics of gravity, evidenced by the recent spectacular results in experimental detection of gravity waves by the LIGO Scientific Collaboration, shows dramatically that there is new physics to be seen and understood in space-time science. Those systems require strain measurements at less than or equal to 10-20 As we discuss here, cold atom optical frequency references are still many orders of magnitude away from the frequency stability that should be achievable with narrow-linewidth quantum transitions and large numbers of very cold atoms, and they may be able to achieve levels of phase stability, ΔΦ/Φtotal ≤ 10-20, that could make an important impact in gravity wave science.This article is part of the themed issue 'Quantum technology for the 21st century'.
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OBJECTIVE: Evaluate the impact of a non-neonatal intensive care unit (NICU)-specific peer counseling (PC) program on the cessation of human milk receipt at and post-NICU discharge. STUDY DESIGN: A multivariable logistic regression model used data from 400 mother-infant dyads from a level IV NICU to compare cessation of human milk receipt at NICU discharge by PC program status. Kaplan-Meier distributions and a multivariable Cox proportional hazards model assessed the relationship between participants/non-participants and cessation of human milk post-NICU discharge. RESULTS: No statistically significant differences between groups in cessation of human milk either by or post-discharge were observed. Identified variables associated with the outcome(s) of interest included maternal and infant age, length of stay, presence of a breastfeeding duration goal and frequency of NICU lactation consultant contact. CONCLUSION: Exposure to a non NICU-specific PC program was not associated with human milk receipt either by or post-NICU discharge.
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Aconselhamento/métodos , Leite Humano , Mães , Grupo Associado , Connecticut , Feminino , Humanos , Lactente , Recém-Nascido , Unidades de Terapia Intensiva Neonatal , Estimativa de Kaplan-Meier , Modelos Logísticos , Masculino , Análise Multivariada , Alta do Paciente , Avaliação de Programas e Projetos de SaúdeRESUMO
Polar molecules are desirable systems for quantum simulations and cold chemistry. Molecular ions are easily trapped, but a bias electric field applied to polarize them tends to accelerate them out of the trap. We present a general solution to this issue by rotating the bias field slowly enough for the molecular polarization axis to follow but rapidly enough for the ions to stay trapped. We demonstrate Ramsey spectroscopy between Stark-Zeeman sublevels in (180)Hf(19)F(+) with a coherence time of 100 milliseconds. Frequency shifts arising from well-controlled topological (Berry) phases are used to determine magnetic g factors. The rotating-bias-field technique may enable using trapped polar molecules for precision measurement and quantum information science, including the search for an electron electric dipole moment.
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A powerful set of universal relations, centered on a quantity called the contact, connects the strength of short-range two-body correlations to the thermodynamics of a many-body system with zero-range interactions. We report on measurements of the contact, using rf spectroscopy, for an (85)Rb atomic Bose-Einstein condensate (BEC). For bosons, the fact that contact spectroscopy can be used to probe the gas on short time scales is useful given the decreasing stability of BECs with increasing interactions. A complication is the added possibility, for bosons, of three-body interactions. In investigating this issue, we have located an Efimov resonance for (85)Rb atoms with loss measurements and thus determined the three-body interaction parameter. In our contact spectroscopy, in a region of observable beyond-mean-field effects, we find no measurable contribution from three-body physics.
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Extracellular single neuron recordings of primary vestibular neurons in Scarpa's ganglion in guinea pigs show that low-intensity 500 Hz bone-conducted vibration (BCV) or 500 Hz air-conducted sound (ACS) activate a high proportion of otolith irregular neurons from the utricular and saccular maculae but few semicircular canal neurons. In alert guinea pigs, and humans, 500 Hz BCV elicits otolith-evoked eye movements. In humans, it also elicits a myogenic potential on tensed sternocleidomastoid muscles. Although BCV and ACS activate both utricular and saccular maculae, it is possible to probe the functional status of these two sense organs separately because of their differential neural projections. Saccular neurons have a strong projection to neck muscles and a weak projection to the oculomotor system. Utricular afferents have a strong projection to eye muscles. So measuring oculomotor responses to ACS and BCV predominantly probes utricular function, while measuring neck muscle responses to these stimuli predominantly probes saccular function.
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Membrana dos Otólitos/inervação , Membrana dos Otólitos/fisiologia , Testes de Função Vestibular/métodos , Estimulação Acústica , Animais , Condução Óssea/fisiologia , Eletromiografia , Movimentos Oculares/fisiologia , Cobaias , Humanos , Doença de Meniere/fisiopatologia , Músculos do Pescoço/fisiologia , Músculos Oculomotores/inervação , Músculos Oculomotores/fisiologia , Reflexo Vestíbulo-Ocular/fisiologia , Sáculo e Utrículo/fisiologia , Canais Semicirculares/fisiologia , Nervo Vestibular/fisiologia , Vestíbulo do Labirinto/fisiologia , Vestíbulo do Labirinto/fisiopatologia , VibraçãoRESUMO
In complementary images of coordinate-space and momentum-space density in a trapped 2D Bose gas, we observe the emergence of presuperfluid behavior. As phase-space density ρ increases toward degenerate values, we observe a gradual divergence of the compressibility κ from the value predicted by a bare-atom model, κ(ba). κ/κ(ba) grows to 1.7 before ρ reaches the value for which we observe the sudden emergence of a spike at p = 0 in momentum space. Momentum-space images are acquired by means of a 2D focusing technique. Our data represent the first observation of non-mean-field physics in the presuperfluid but degenerate 2D Bose gas.
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We report on measurements of the excitation spectrum of a strongly interacting Bose-Einstein condensate. A magnetic-field Feshbach resonance is used to tune atom-atom interactions in the condensate and to reach a regime where quantum depletion and beyond mean-field corrections to the condensate chemical potential are significant. We use two-photon Bragg spectroscopy to probe the condensate excitation spectrum; our results demonstrate the onset of beyond mean-field effects in a gaseous Bose-Einstein condensate.
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To decipher and manipulate the 14 000 identified Drosophila genes, there is a need to inject a large number of embryos with transgenes. We have developed an automated instrument for high throughput injection of Drosophila embryos. It was built on an inverted microscope, equipped with a motorized xy stage, autofocus, a charge coupled device camera, and an injection needle mounted on a high speed vertical stage. A novel, micromachined embryo alignment device was developed to facilitate the arrangement of a large number of eggs. The control system included intelligent and dynamic imaging and analysis software and an embryo injection algorithm imitating a human operator. Once the injection needle and embryo slide are loaded, the software automatically images and characterizes each embryo and subsequently injects DNA into all suitable embryos. The ability to program needle flushing and monitor needle status after each injection ensures reliable delivery of biomaterials. Using this instrument, we performed a set of transformation injection experiments. The robot achieved injection speeds and transformation efficiencies comparable to those of a skilled human injector. Because it can be programed to allow injection at various locations in the embryo, such as the anterior pole or along the dorsal or ventral axes, this system is also suitable for injection of general biochemicals, including drugs and RNAi.
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DNA/administração & dosagem , Drosophila/embriologia , Drosophila/genética , Injeções/instrumentação , Robótica/instrumentação , Transfecção/instrumentação , Animais , Animais Geneticamente Modificados , DNA/genética , Desenho de Equipamento , Análise de Falha de Equipamento , Injeções/métodos , Reprodutibilidade dos Testes , Robótica/métodos , Sensibilidade e Especificidade , Manejo de Espécimes/instrumentação , Manejo de Espécimes/métodos , Transfecção/métodosRESUMO
We observe the proliferation of vortices in the Berezinskii-Kosterlitz-Thouless regime on a two-dimensional array of Josephson-coupled Bose-Einstein condensates. As long as the Josephson (tunneling) energy J exceeds the thermal energy T, the array is vortex free. With decreasing J/T, vortices appear in the system in ever greater numbers. We confirm thermal activation as the vortex-formation mechanism and obtain information on the size of bound vortex pairs as J/T is varied.
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We report on the first measurement of a temperature dependence of the Casimir-Polder force. This measurement was obtained by positioning a nearly pure 87Rb Bose-Einstein condensate a few microns from a dielectric substrate and exciting its dipole oscillation. Changes in the collective oscillation frequency of the magnetically trapped atoms result from spatial variations in the surface-atom force. In our experiment, the dielectric substrate is heated up to 605 K, while the surrounding environment is kept near room temperature (310 K). The effect of the Casimir-Polder force is measured to be nearly 3 times larger for a 605 K substrate than for a room-temperature substrate, showing a clear temperature dependence in agreement with theory.
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We report the observation of vortex pinning in rotating gaseous Bose-Einstein condensates. Vortices are pinned to columnar pinning sites created by a corotating optical lattice superimposed on the rotating Bose-Einstein condensates. We study the effects of two types of optical lattice: triangular and square. In both geometries we see an orientation locking between the vortex and the optical lattices. At sufficient intensity the square optical lattice induces a structural crossover in the vortex lattice.
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We investigate the production efficiency of ultracold molecules in bosonic 85Rb and fermionic 40K when the magnetic field is swept across a Feshbach resonance. For adiabatic sweeps of the magnetic field, our novel model shows that the conversion efficiency of both species is solely determined by the phase space density of the atomic cloud, in contrast with a number of theoretical predictions. In the nonadiabatic regime our measurements of the 85Rb molecule conversion efficiency follow a Landau-Zener model.
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Repulsive laser potential pulses applied to vortex lattices of rapidly rotating Bose-Einstein condensates create propagating density waves which we have observed experimentally and modeled computationally to high accuracy. We have observed a rich variety of dynamical phenomena ranging from interference effects and shock-wave formation to anisotropic sound propagation.
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When humans are roll-tilted around the naso-occipital axis, both eyes roll or tort in the opposite direction to roll-tilt, a phenomenon known as ocular counterroll (OCR). While the magnitude of OCR is primarily determined by vestibular, somatosensory, and proprioceptive input, direction of gaze also plays a major role. The aim of this study was to measure the interaction between some of these factors in the control of OCR. Videooculography was used to measure 3D eye position during maintained whole body (en bloc) static roll-tilt in darkness, while subjects fixated first on a distant (at 130 cm) and then a near (at 30 cm) head-fixed target aligned with the subject's midline. We found that while converging on the near target, human subjects displayed a significant reduction in OCR for both directions of roll-tilt--i.e. the interaction between OCR and vergence was not simple addition or subtraction of torsion induced by vergence with torsion induced by roll-tilt. To remove the possibility that the OCR reduction may be associated with the changed horizontal position of the eye in the orbit during symmetric convergence, we ran an experiment using asymmetric convergence in which the distant and near targets were aligned directly in front of one eye. We found the magnitude of OCR in this asymmetric convergence case was also reduced for near viewing by about the same amount as in the symmetric vergence condition, confirming that the convergence command rather than horizontal position of the eye underlies the OCR reduction, since there was no horizontal movement of the aligned eye in the orbit between fixation on the distant and near targets. Increasing vergence from 130 to 30 cm reduced OCR gain by around 35% on average. That reduction was equal in both eyes and occurred in both the symmetric and asymmetric convergence conditions. These results demonstrate the important role vergence plays in determining ocular counterroll during roll-tilt and may support the contention that vergence acts to reduce the conflict facing a stereopsis-generating mechanism.
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Convergência Ocular/fisiologia , Percepção de Profundidade/fisiologia , Movimentos Oculares/fisiologia , Movimentos da Cabeça/fisiologia , Adulto , Feminino , Fixação Ocular/fisiologia , Humanos , Masculino , Anormalidade Torcional/fisiopatologia , Gravação de Videoteipe , Visão Binocular/fisiologiaRESUMO
We create rapidly rotating Bose-Einstein condensates in the lowest Landau level by spinning up the condensates to rotation rates Omega > 99% of the centrifugal limit for a harmonically trapped gas, while reducing the number of atoms. As a consequence, the chemical potential drops below the cyclotron energy 2 variant Planck's over 2pi Omega. While in this mean-field quantum-Hall regime we still observe an ordered vortex lattice, its elastic shear strength is strongly reduced, as evidenced by the observed very low frequency of Tkachenko modes. Furthermore, the gas approaches the quasi-two-dimensional limit. The associated crossover from interacting- to ideal-gas behavior along the rotation axis results in a shift of the axial breathing mode frequency.
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We investigate the relationship between the coherence of a partially Bose-condensed spinor gas and its temperature. We observe cooling of the normal component driven by decoherence as well as the effect of temperature on decoherence rates.
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Coherent behavior of spinor Bose-Einstein condensates is studied in the presence of a significant uncondensed (normal) component. Normal-superfluid exchange scattering leads to near-perfect local alignment between the spin fields of the two components. We observe that, through this spin locking, spin-domain formation in the condensate is vastly accelerated as the spin populations in the condensate are entrained by large-amplitude spin waves in the normal component.
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We directly image Tkachenko waves in a vortex lattice in a dilute-gas Bose-Einstein condensate. The low (sub-Hz) resonant frequencies are a consequence of the small but nonvanishing elastic shear modulus of the vortex-filled superfluid. The frequencies are measured for rotation rates as high as 98% of the centrifugal limit for the harmonically confined gas. Agreement with a hydrodynamic theory worsens with increasing rotation rate, perhaps due to the increasing fraction of the volume displaced by the vortex cores. We also observe two low-lying m=0 longitudinal modes at about 20 times higher frequency.
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We study the formation of large vortex aggregates in a rapidly rotating dilute-gas Bose-Einstein condensate. When we remove atoms from the rotating condensate with a tightly focused, resonant laser, the density can be locally suppressed, while fast circulation of a ring-shaped superflow around the area of suppressed density is maintained. Thus a giant vortex core comprising 7 to 60 phase singularities is formed. The giant core is only metastable, and it will refill with distinguishable single vortices after many rotation cycles. The surprisingly long lifetime of the core can be attributed to the influence of strong Coriolis forces in the condensate. In addition we have been able to follow the precession of off-center giant vortices for more than 20 cycles.
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We have studied the dynamics of large vortex lattices in a dilute-gas Bose-Einstein condensate. While undisturbed lattices have a regular hexagonal structure, large-amplitude quadrupolar shape oscillations of the condensate are shown to induce a wealth of nonequilibrium lattice dynamics. When exciting an m=-2 mode, we observe shifting of lattice planes, changes of lattice structure, and sheetlike structures in which individual vortices appear to have merged. Excitation of an m=+2 mode dissolves the regular lattice, leading to randomly arranged but still strictly parallel vortex lines.