RESUMO
Ancient DNA shows continuity between living and ancient Maya communities.
Assuntos
Comportamento Ritualístico , Civilização , DNA Antigo , Gêmeos , Feminino , Humanos , Masculino , História Antiga , Gêmeos/história , Criança , Civilização/históriaRESUMO
Complex tools from 300,000-year-old deposit at Schöningen in Germany point to a "wood age".
Assuntos
Homem de Neandertal , Madeira , Animais , Arqueologia , Alemanha , Homem de Neandertal/psicologiaRESUMO
Moderns made mysterious ice age artifacts-implying overlap with Neanderthals.
Assuntos
Homem de Neandertal , Animais , Humanos , Europa (Continente) , FósseisRESUMO
Among Europeans, risk of multiple sclerosis rises with genes from Bronze Age Yamnaya herders.
Assuntos
DNA Antigo , Esclerose Múltipla , Humanos , Europa (Continente)/epidemiologia , Genoma Humano , Esclerose Múltipla/epidemiologia , Esclerose Múltipla/genética , Esclerose Múltipla/históriaRESUMO
8000 years ago-long before farming arrived-people in Siberia built defensive structures.
Assuntos
Caça , Humanos , Fazendas/história , Sibéria , Caça/históriaRESUMO
Giant family trees based on ancient DNA from thousands of people are revealing prehistoric politics and social structure.
RESUMO
Despite more than 80 years of use in a number of conditions, including in critically ill patients, comments have recently arisen regarding the safety and efficacy of human serum albumin (HSA) as a therapeutic product and stabilizer/excipient in botulinum neurotoxins. This review summarizes the literature on the safety of HSA. Beyond decades of safe use, the largest clinical dataset of HSA safety is a large meta-analysis of HSA supplier data, which found only an extremely remote risk of serious adverse events across millions of doses of therapeutic concentrations of HSA. There is a paucity of literature identifying HSA-specific adverse events when used as a stabilizer/excipient; however, studies of HSA-containing botulinum neurotoxins (BoNTs) suggest that adverse events are not related to HSA. Polysorbates, which are synthetically produced and not physiologically inert, are contained in pending or new-to-market BoNT formulations. In contrast to HSA, evidence exists to suggest that polysorbates (particularly PS20/PS80) can cause serious adverse events (e.g., hypersensitivity, anaphylaxis, and immunogenicity).
Assuntos
Toxinas Botulínicas Tipo A , Toxinas Botulínicas , Humanos , Toxinas Botulínicas/efeitos adversos , Albumina Sérica Humana/efeitos adversos , Excipientes , Polissorbatos , Toxinas Botulínicas Tipo A/efeitos adversosRESUMO
DNA from enslaved Black workers at a 19th century iron forge links them to living descendants. But the research swirls with ethical questions.
RESUMO
After the Spanish conquest, horses transformed Native American tribes much earlier than historians thought.
Assuntos
Indígena Americano ou Nativo do Alasca , Cavalos , Interação Humano-Animal , Animais , América do Norte , Espanha , Arqueologia , HumanosRESUMO
Ancient DNA reflects foreign influx to Swahili coast, but its culture is largely local.
RESUMO
Genes reveal striking diversity within similar ice age cultures.
Assuntos
Diversidade Cultural , DNA Antigo , Europa (Continente) , HumanosRESUMO
Analysis reveals the chemicals applied to corpses in a 2700-year-old mummification workshop.
Assuntos
Múmias , Humanos , Cadáver , Egito , História Antiga , Múmias/históriaRESUMO
Meat from the butchered beasts would have fed hundreds.
Assuntos
Comportamento Alimentar , Processos Grupais , Caça , Carne , Homem de Neandertal , Animais , Ingestão de Alimentos , Carne/história , Homem de Neandertal/psicologia , Caça/história , ElefantesRESUMO
DNA from a medieval German cemetery opens a window on the history of today's largest Jewish population.
Assuntos
Judeus , Judeus/genética , População/genética , Alemanha , Cemitérios/história , DNA Antigo , HumanosRESUMO
By sequencing ancient hominins' DNA, Pääbo explored "what makes us uniquely human".
Assuntos
DNA Antigo , Hominidae , Animais , Hominidae/genética , Humanos , Prêmio NobelRESUMO
Genetic study of burials suggests whole families migrated to the island in the first millennium C.E.
Assuntos
Emigração e Imigração , População Branca , Sepultamento , DNA Antigo , Emigração e Imigração/história , Inglaterra , História Antiga , Humanos , Análise de Sequência de DNA , População Branca/genéticaRESUMO
Studies seek clues to origins of farming, early languages.
Assuntos
Civilização , DNA Antigo , Fazendas , Idioma , Civilização/história , Fazendas/história , História Antiga , Humanos , Idioma/história , Oriente MédioRESUMO
Russian disinformation campaign targets routine research on bat parasites.
RESUMO
Researchers hide ancient weapons and bat skulls, upload data as bombs fall.