RESUMO
A family of neutral bis-cyclometalated iridium complexes [Ir(C^N)2(LX)] has been investigated as ECL labels under immunoassay conditions. Among them, the complex based on phenylphenanthridine (pphent) as the C^N ligand, exhibits outstanding performance and it is a candidate to substitute the commercially available Ru-based label in diagnostics.
Assuntos
Técnicas Eletroquímicas , Irídio/química , Luminescência , Compostos Organometálicos/química , Processos Fotoquímicos , Água/química , Imunoensaio , SoluçõesRESUMO
Previously unknown diaryl esters of l-tartaric acid have been synthesized. Their conformations have been studied by DFT calculations, NMR and circular dichroism spectroscopy in solution, as well as by X-ray diffraction in the crystalline state. The four-carbon tartrate chain of diaryl esters was found to be extended in all cases, with a higher degree of nonplanarity in the crystals. Dinaphthyl tartrates show unusually strong exciton Cotton effects (A = -228 for di-1-naphthyl l-tartrate) due to the coupling of allowed 1B(b) transitions in naphthyl chromophores, despite the acyclic structure and significant distance (over 10 A) between the two chromophores.