RESUMO
We present an unusual cause of respiratory arrest resulting from sole ingestion of home-brewed opium tea. A 64-year-old woman was found unresponsive and in respiratory arrest by a first responder. There were no obvious signs of regular recreational drug use. On presentation to the local district general hospital, the patient was in extremis, with severe physiological and biochemical derangements. A naloxone infusion was commenced and she later made a good recovery. It was subsequently discovered that she had brewed opium tea from opium buds she had picked from a nearby commercial poppy farm, a practice she had learnt while in Afghanistan.
Assuntos
Transtornos Relacionados ao Uso de Opioides/diagnóstico , Ópio/toxicidade , Chá/toxicidade , Administração Intravenosa , Afeganistão , Coma/diagnóstico , Coma/etiologia , Feminino , Humanos , Pessoa de Meia-Idade , Naloxona/administração & dosagem , Naloxona/uso terapêutico , Antagonistas de Entorpecentes/administração & dosagem , Antagonistas de Entorpecentes/uso terapêutico , Transtornos Relacionados ao Uso de Opioides/epidemiologia , Ópio/administração & dosagem , Resultado do TratamentoRESUMO
PURPOSE: To report a corneal infection due to Corynebacterium propinquum identified using the matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) method. METHODS: A 94-year-old woman presented with suppurative keratitis. Her ocular history included Fuchs corneal dystrophy, corneal transplantation, and glaucoma. A gram-stained smear revealed coryneforms. Colonies on bacterial culture media were assayed by MALDI-TOF. RESULTS: Identification of C. propinquum was confirmed by RNA polymerase ß subunit (rpoB) gene sequencing. The patient was treated with topical cefazolin, gentamicin, and fluorometholone, and her vision improved to 20/160 unaided when last seen. CONCLUSIONS: MALDI-TOF can correctly identify isolates that are both uncommon and difficult to distinguish from related species. The ease and low running costs of this method will improve the laboratory diagnosis of ocular infections.
Assuntos
Úlcera da Córnea/diagnóstico , Infecções por Corynebacterium/diagnóstico , Corynebacterium/isolamento & purificação , Infecções Oculares Bacterianas/diagnóstico , Espectrometria de Massas por Ionização e Dessorção a Laser Assistida por Matriz , Idoso de 80 Anos ou mais , Antibacterianos/uso terapêutico , Cefazolina/uso terapêutico , Úlcera da Córnea/tratamento farmacológico , Úlcera da Córnea/microbiologia , Corynebacterium/genética , Infecções por Corynebacterium/tratamento farmacológico , Infecções por Corynebacterium/microbiologia , RNA Polimerases Dirigidas por DNA/genética , Quimioterapia Combinada , Infecções Oculares Bacterianas/tratamento farmacológico , Infecções Oculares Bacterianas/microbiologia , Feminino , Fluormetolona/uso terapêutico , Genes Bacterianos/genética , Gentamicinas/uso terapêutico , HumanosRESUMO
This study builds on previous results published on the synthesis and characterization of laponite-supported titania photocatalysts. Titania nanocrystals are prepared prior to addition to the clay dispersion, by a sol-gel synthesis incorporating a microwave hydrothermal step. In addition to previously examinations with XRD, TEM, and FT-IR, the samples are further characterized with SEM, 29Si NMR, and BET N2 sorption to gain additional insight into the effect of TiO2 concentration and surface area on the photoactivity of the samples.
RESUMO
This study examines the edge modification of laponite, with a monoalkoxy silane, dimethyl-octylmethoxysilane. The influence of ultrasonics, aging time and silane concentration on the resultant materials is examined. The silylated clays are characterized by XRD, IES, TGA, and Si NMR. The amount of grafted silane was increased by increasing the ratio of silane to clay, sonication of the reaction mixture and ageing the reaction mixture for no more than 24 h to avoid removal of grafted silane due to equilibrium effects.
RESUMO
This study examines the use of laponite, a synthetic smectite, which forms exfoliated silicate layers when dispersed in water, as an inorganic support for titania nanocrystals. Titania nanocrystals are prepared prior to addition to the clay dispersion, by a sol-gel synthesis incorporating a microwave hydrothermal step. The characteristics of the resultant structure such as titania phase, crystallite size, and particulate size are examined via X-ray diffraction (XRD), transmission electron spectroscopy (TEM), and infrared spectroscopy.