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1.
Neurointervention ; 2024 Oct 16.
Artigo em Inglês | MEDLINE | ID: mdl-39406348

RESUMO

PURPOSE: Intracranial mycotic aneurysms (IMAs), rare and often life-threatening, result from arterial wall infections typically caused by bacteria such as Staphylococcus and Streptococcus. The standard treatment for ruptured aneurysms is not well-defined and often individualized. This study investigates the efficacy of endovascular glue embolization in managing ruptured IMAs, based on our center's experience. MATERIALS AND METHODS: A retrospective analysis was conducted for ruptured IMAs treated with glue embolization between January 2016 and December 2023. The procedure involved aneurysm sac and parent vessel occlusion with glue delivery. Data included patient demographics, clinical presentations, and neuroimaging. Clinical outcomes were assessed using the modified Rankin scale (mRS) at 3 months, and angiographic follow-up was conducted at 6 months. RESULTS: The study included 28 patients, predominantly male (64.3%), with a mean age of 48 years. Headache was the primary symptom in 92.9% of cases, and positive blood/cerebro spinal fluid cultures were found in 82.14% of cases. All aneurysms were located in the distal circulation, primarily in the anterior circulation system. Glue embolization was successfully performed in all cases, achieving complete aneurysm sac and parent vessel obliteration. Follow-up at 3 months indicated mRS scores of 0 or 1 in 96.5% of cases. Six-month angiographic follow-up showed no aneurysm regrowth or new formations. CONCLUSION: Endovascular glue embolization demonstrated high efficacy and safety in treating ruptured IMAs, with a 100% obliteration rate and favorable clinical outcomes in this single-center experience. Despite limitations such as its retrospective design and small sample size, the study supports glue embolization as a viable, less invasive alternative to traditional surgery. Further comparative studies are needed to confirm these findings and refine treatment approaches.

2.
World Neurosurg ; 136: 37-43, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-31917306

RESUMO

BACKGROUND: Intramedullary spinal cord dermoid tumors are rare. Early diagnosis with appropriate imaging is of utmost importance for a good outcome. Gross total resection is the treatment of choice for optimal results. Neurosurgical intervention for any intramedullary lesion is fraught with problems because of the nature of the lesion and handling of the spinal cord, which is already compromised because of the intramedullary lesion. Recurrence of the intramedullary dermoid tumor is frequent because of incomplete resection of the tumor. Most commonly, patients present with worsening of neurologic deficits. Inadequate resection because of the fear of worsening the neurologic deficits is associated with significant complications. CASE DESCRIPTION: We report a case of an intramedullary dermoid tumor in a child that was associated with myriad of complications owing to incomplete resection of the tumor. The patient underwent multiple interventions at various centers which resulted in serious multiple complications before presenting at our center for further management. CONCLUSIONS: This report highlights the spectrum of complications that can develop in a patient varying from worsening of the deficits to meningitis and subsequent development of hydrocephalus.


Assuntos
Cisto Dermoide/cirurgia , Hidrocefalia/cirurgia , Meningite Asséptica/terapia , Procedimentos Neurocirúrgicos , Complicações Pós-Operatórias/cirurgia , Sepse/terapia , Neoplasias da Medula Espinal/cirurgia , Derrame Subdural/cirurgia , Descompressão Cirúrgica , Cisto Dermoide/complicações , Cisto Dermoide/patologia , Feminino , Humanos , Lactente , Laminectomia , Vértebras Lombares/cirurgia , Imageamento por Ressonância Magnética , Neoplasia Residual , Complicações Pós-Operatórias/diagnóstico por imagem , Reoperação , Sacro , Neoplasias da Medula Espinal/complicações , Neoplasias da Medula Espinal/patologia , Derrame Subdural/diagnóstico por imagem , Vértebras Torácicas/cirurgia , Tomografia Computadorizada por Raios X , Derivação Ventriculoperitoneal
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