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Ann Biomed Eng ; 41(9): 1860-8, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-23471817

RESUMO

Pediatricians in Africa requested a tool to improve caregiver dosing of liquid antiretroviral medication. We developed, evaluated and disseminated a clip to control the amount of medication drawn into an oral syringe. In a laboratory, a user tested clips of different lengths, corresponding to different volumes, by drawing water into a syringe with a clip. In Texas and Malawi, 149 adults attempted to measure Pepto-Bismol™ using a syringe with a clip, a syringe without a clip, and a dosing cup, in a randomly assigned order. In the laboratory, the volume of liquid, ranging from 1 to 4.5 mL, drawn into the syringe was always within at least 5 µL of the intended dose. In Texas, 84% of doses were accurate within ±10%, vs. 63% using the syringe alone, and 21% with the dosing cup. In Malawi, 98% of doses were accurate to within ±10%, vs. 90% using the syringe alone, and 27% with the dosing cup. For target accuracy values within ±45% (±21%), a significantly higher fraction of Houston (Kamangira) participants delivered an accurate dose using the syringe with the clip than with the syringe alone (p < 0.05). The clip enables a greater proportion of users to accurately measure liquid medication.


Assuntos
Antidiarreicos/administração & dosagem , Bismuto/administração & dosagem , Compostos Organometálicos/administração & dosagem , Salicilatos/administração & dosagem , Seringas/normas , Administração Oral , Adulto , Desenho de Equipamento/métodos , Feminino , Humanos , Masculino , Seringas/tendências
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