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1.
Environ Res ; 223: 115444, 2023 04 15.
Artigo em Inglês | MEDLINE | ID: mdl-36758921

RESUMO

The flue gas composition is often measured using a combination of techniques that differ in terms of both physical operation principle and type of output. Gas analyzers, FTIR spectrometers, and mass spectrometers are the most popular tools used for this purpose. In this research, we study the composition of the flue gas from the combustion of fuel slurries and dry composite fuels based on industrial and agricultural waste. It has been established that the use of slurry fuels makes the anthropogenic emissions 2-4 times lower than from the combustion of coal slime. For example, the CO2 emissions from the combustion of dry coal slime were 2.5-3.7 times higher than from the combustion of slurry fuels. In addition, the combustion of slurry fuels made it possible to cut down the nitrogen oxide emissions by 1.3-1.5 times and sulfur oxide emissions by 1.3-2.7 times. A comparison of the results obtained using different measurement techniques has shown that differences between the CO and CO2 content in the combustion products measured by a gas analyzer and an FTIR spectrometer did not exceed 20%. The use of FTIR spectroscopy provided new knowledge on the concentrations of hydrocarbons from the combustion of fuels based on promising industrial wastes.


Assuntos
Poluentes Atmosféricos , Carvão Mineral , Dióxido de Carbono/análise , Água , Óxidos de Nitrogênio/análise , Resíduos Industriais , Poluentes Atmosféricos/análise
2.
Environ Pollut ; 285: 117390, 2021 Sep 15.
Artigo em Inglês | MEDLINE | ID: mdl-34049129

RESUMO

This paper presents the results of experimental research into the component composition of gases and ash residue from the combustion of a set of high-potential coal-water slurries containing petrochemicals. We have established that the use of slurry fuels provides a decrease in the CO2, CH4, SO2, and NOx concentrations as compared to those from coal combustion. The content of carbon monoxide and hydrogen in the gas environment from the combustion of slurries is higher due to the intense water evaporation. It is shown that adding biomass allows a further 5-33% reduction in the emissions of nitrogen and sulfur oxides as compared to the coal-water slurry and the composition with added waste turbine oil and a 23-68% decrease as compared to coal (per unit mass of the fuel burnt). The mechanisms and stages of CO2, SO2, and NOx formation are explained with a view to controlling gaseous anthropogenic emissions and ash buildup. The values of the relative environmental performance indicator are calculated for slurry fuels. It is shown to exceed the same indicator of bituminous coal by 28-56%.


Assuntos
Poluentes Atmosféricos , Carvão Mineral , Poluentes Atmosféricos/análise , Carvão Mineral/análise , Gases , Pirólise , Água
4.
Prikl Biokhim Mikrobiol ; 27(4): 523-8, 1991.
Artigo em Russo | MEDLINE | ID: mdl-1745647

RESUMO

A polyamide with the covalently coupled phosphatidyl ethanolamine was used for affinity adsorption of an alkaline lipase from Pseudomonas aeruginosa. The immobilization resulted in increase of the enzyme specific activity. Some properties of native and adsorbed enzyme were compared. The temperature optima, heat and pH stability, KM and Vmax values were determined for both native and immobilized enzymes.


Assuntos
Enzimas Imobilizadas , Lipase/metabolismo , Pseudomonas aeruginosa/enzimologia , Concentração de Íons de Hidrogênio , Hidrólise , Cinética , Fosfatidiletanolaminas/metabolismo , Especificidade por Substrato , Temperatura
5.
Artigo em Russo | MEDLINE | ID: mdl-1666233

RESUMO

The title method was applied to the treatment of schizophrenic patients suffering from schizoaffective, paranoid and hallucinatory paranoid attacks. Definite correlations were established between the development of insulin coma and the type of the reverse development of psychosis. Five variants of schizophrenia reduction due to the treatment method under consideration were distinguished and described: variant 1--harmonic critical, variant 2--harmonic lytic, variant 3--disharmonious deliric, variant 4--disharmonious affective, and variant 5--incomplete reduction. The established correlations between variants of the development of insulin coma and the type of psychosis reduction enable one to predict whether the use of forced insulin coma therapy will be desirable and effective.


Assuntos
Convulsoterapia , Esquizofrenia/terapia , Doença Crônica , Estudos de Avaliação como Assunto , Humanos , Hipoglicemia/sangue , Masculino , Prognóstico , Esquizofrenia/sangue , Esquizofrenia/classificação , Fatores de Tempo
7.
Farmakol Toksikol ; 48(4): 65-9, 1985.
Artigo em Russo | MEDLINE | ID: mdl-3840096

RESUMO

The authors have developed algorithms and programs that permit introduction in the dialogue mode of the data pertinent to the time-course of changes in the concentrations and pharmacological effects, calculation of up to 20 pharmacokinetic parameters, establishment of the relationship between the effect and concentration, and prediction of the expected effects under different drug dosage regimens. The ASPID is based on the FORTRAN-IV language.


Assuntos
Computadores , Processamento Eletrônico de Dados/métodos , Preparações Farmacêuticas/metabolismo , Software , Relação Dose-Resposta a Droga , Humanos , Cinética , Matemática , Preparações Farmacêuticas/administração & dosagem , Fatores de Tempo
8.
Antibiot Med Biotekhnol ; 30(3): 228-32, 1985 Mar.
Artigo em Russo | MEDLINE | ID: mdl-4015063

RESUMO

The pharmacokinetics of ampicillin was studied in 38 patients with acute pyelonephritis in the second and third trimesters of pregnancy after the first and the last (28th-32nd) intramuscular injections of the antibiotic. The ampicillin levels in the blood and urine were determined with the agar diffusion method. The pharmacokinetic parameters were estimated in a one-compartmental model by computer The ampicillin levels in the blood and urine of the patients did not practically differ at all the investigation periods (0.5-6 hours after the antibiotic administration) in the second and third trimesters of pregnancy. During the treatment, the rate of ampicillin elimination from the host increased and the period of half-elimination from the blood decreased. The antibiotic levels in the urine within 4-6 hours after the last injection were practically lower in the second trimester of pregnancy as compared with the second trimester. The therapy resulted in an increase in the antibiotic renal clearance, which returned to normal in the second trimester of pregnancy and remained under normal in the third trimester of pregnancy. The increase was due to an approximately 2-fold acceleration of the rate of ampicillin secretion by the renal tubules. The total clearance of ampicillin practically increased in the second trimester of pregnancy and remained decreased in the third trimester of pregnancy. The estimation performed in accordance with the Krueger-Timmer principles on the basis of the characteristic features of the pharmacokinetics of ampicillin shown in the study provides recommendation of the following scheme for pyelonephritis treatment in pregnant women: 500 mg of ampicillin injected intramuscularly every 6 hours followed by gradual decreasing of the intervals between the injections to 4 hours as the rate of ampicillin elimination increases.


Assuntos
Ampicilina/metabolismo , Complicações Infecciosas na Gravidez/tratamento farmacológico , Pielonefrite/tratamento farmacológico , Doença Aguda , Ampicilina/administração & dosagem , Disponibilidade Biológica , Feminino , Humanos , Injeções Intramusculares , Cinética , Taxa de Depuração Metabólica , Gravidez , Complicações Infecciosas na Gravidez/metabolismo , Segundo Trimestre da Gravidez , Terceiro Trimestre da Gravidez , Pielonefrite/metabolismo , Fatores de Tempo
9.
Antibiot Med Biotekhnol ; 30(2): 124-8, 1985 Feb.
Artigo em Russo | MEDLINE | ID: mdl-4004185

RESUMO

The pharmacokinetics of cefuroxime was studied in 40 pregnant women with acute pyelonephritis. The women were in the 2nd and 3rd terms of pregnancy. The antibiotic was injected in a dose of 500 mg. The antibiotic levels in the blood and urine were determined with the agar diffusion method. The pharmacokinetic parameters were measured in a one-compartmental model with regard to antibiotic absorption. The measurement was performed with the use of computer. The cefuroxime concentrations in the blood and urine were practically the same at all periods of the study and at different terms of pregnancy. In pregnant women with acute pyelonephritis, the volume of cefuroxime distribution and the time of a two-fold decrease in the blood antibiotic levels increased. The estimation of the optimal scheme of cefuroxime dosing by the Krueger-Timer principles provided treatment of acute pyelonephritis in pregnant women with intramuscular injections of the antibiotic in a dose of 500 mg every 8 hours for 7-8 days.


Assuntos
Cefuroxima/metabolismo , Cefalosporinas/metabolismo , Complicações Infecciosas na Gravidez/tratamento farmacológico , Pielonefrite/tratamento farmacológico , Doença Aguda , Adolescente , Adulto , Disponibilidade Biológica , Cefuroxima/uso terapêutico , Feminino , Meia-Vida , Humanos , Cinética , Taxa de Depuração Metabólica , Gravidez , Segundo Trimestre da Gravidez , Terceiro Trimestre da Gravidez
10.
Farmakol Toksikol ; 48(1): 43-5, 1985.
Artigo em Russo | MEDLINE | ID: mdl-2858404

RESUMO

The time-course of the antiexudative effect of the antihistaminic drugs diphenhydramine, phencarol and suprastin was studied in experimental dextran edema of the rat hind limb after intragastric administration of the drugs in a dose of 50 mg/kg. The data obtained were correlated to the time-course of the blood serum drug concentration measured by high pressure liquid chromatography. The relationship between the pharmacological action of the drugs and the mean maintenance dose was depicted by means of computer. It has been shown that the antiexudative activity of diphenhydramine and phencarol is approximately identical, whereas the efficacy of suprastin is several times less.


Assuntos
Edema/tratamento farmacológico , Antagonistas dos Receptores Histamínicos H1/uso terapêutico , Animais , Compostos Benzidrílicos/sangue , Compostos Benzidrílicos/uso terapêutico , Cromatografia Líquida , Difenidramina/sangue , Difenidramina/uso terapêutico , Avaliação Pré-Clínica de Medicamentos , Edema/sangue , Etilenodiaminas/sangue , Etilenodiaminas/uso terapêutico , Antagonistas dos Receptores Histamínicos H1/sangue , Masculino , Modelos Biológicos , Ratos
11.
Prikl Biokhim Mikrobiol ; 15(5): 676-81, 1979.
Artigo em Russo | MEDLINE | ID: mdl-42049

RESUMO

Cultivation of the microscopic fungus Rhizopus sp. str. 3-3--producer was investigated. Properties of lipase were studied. The technical preparation liparisopin G3x was obtained and examined. pH optimum of the preparation was within 6.0--7.0 and temperature optimum was 37 degrees C (olive oil used as substrate).


Assuntos
Lipase/biossíntese , Rhizopus/enzimologia , Concentração de Íons de Hidrogênio , Cinética , Lipase/metabolismo , Temperatura
12.
Prikl Biokhim Mikrobiol ; 11(4): 622-5, 1975.
Artigo em Russo | MEDLINE | ID: mdl-1208421

RESUMO

The effect of different amino acids on the hemicellulase synthesis by the fungus Aspergillus awamori 16-4E was investigated. The favorable influence of beta-alanine on the enzyme synthesis was demonstrated. Quantitative changes of beta-alanine and glutamic acid in the cell of Asp. awamori 16-4E were followed during the fungal development.


Assuntos
Aminoácidos/farmacologia , Aspergillus/enzimologia , Glicosídeo Hidrolases/biossíntese , Alanina/metabolismo , Aspergillus/efeitos dos fármacos , Aspergillus/metabolismo , Divisão Celular , Indução Enzimática/efeitos dos fármacos , Glutamatos/metabolismo
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