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1.
Phys Rev Lett ; 132(6): 060401, 2024 Feb 09.
Artigo em Inglês | MEDLINE | ID: mdl-38394576

RESUMO

The interaction between a quantum system and its environment limits our ability to control it and perform quantum operations on it. We present an efficient method to find optimal controls for quantum systems coupled to non-Markovian environments, by using the process tensor to compute the gradient of an objective function. We consider state transfer for a driven two-level system coupled to a bosonic environment, and characterize performance in terms of speed and fidelity. This allows us to determine the best achievable fidelity as a function of process duration. We show there can be a trade-off between speed and fidelity, and that slower processes can have higher fidelity by exploiting non-Markovian effects.

3.
NPJ Digit Med ; 4(1): 132, 2021 Sep 07.
Artigo em Inglês | MEDLINE | ID: mdl-34493770

RESUMO

Privacy protection is paramount in conducting health research. However, studies often rely on data stored in a centralized repository, where analysis is done with full access to the sensitive underlying content. Recent advances in federated learning enable building complex machine-learned models that are trained in a distributed fashion. These techniques facilitate the calculation of research study endpoints such that private data never leaves a given device or healthcare system. We show-on a diverse set of single and multi-site health studies-that federated models can achieve similar accuracy, precision, and generalizability, and lead to the same interpretation as standard centralized statistical models while achieving considerably stronger privacy protections and without significantly raising computational costs. This work is the first to apply modern and general federated learning methods that explicitly incorporate differential privacy to clinical and epidemiological research-across a spectrum of units of federation, model architectures, complexity of learning tasks and diseases. As a result, it enables health research participants to remain in control of their data and still contribute to advancing science-aspects that used to be at odds with each other.

4.
Phys Rev Lett ; 126(20): 200401, 2021 May 21.
Artigo em Inglês | MEDLINE | ID: mdl-34110219

RESUMO

We present a general method to efficiently design optimal control sequences for non-Markovian open quantum systems, and illustrate it by optimizing the shape of a laser pulse to prepare a quantum dot in a specific state. The optimization of control procedures for quantum systems with strong coupling to structured environments-where time-local descriptions fail-is a computationally challenging task. We modify the numerically exact time evolving matrix product operator (TEMPO) method, such that it allows the repeated computation of the time evolution of the reduced system density matrix for various sets of control parameters at very low computational cost. This method is potentially useful for studying numerous optimal control problems, in particular in solid state quantum devices where the coupling to vibrational modes is typically strong.

5.
NPJ Digit Med ; 4(1): 49, 2021 Mar 12.
Artigo em Inglês | MEDLINE | ID: mdl-33712693

RESUMO

Contact tracing is increasingly used to combat COVID-19, and digital implementations are now being deployed, many based on Apple and Google's Exposure Notification System. These systems utilize non-traditional smartphone-based technology, presenting challenges in understanding possible outcomes. In this work, we create individual-based models of three Washington state counties to explore how digital exposure notifications combined with other non-pharmaceutical interventions influence COVID-19 disease spread under various adoption, compliance, and mobility scenarios. In a model with 15% participation, we found that exposure notification could reduce infections and deaths by approximately 8% and 6% and could effectively complement traditional contact tracing. We believe this can provide health authorities in Washington state and beyond with guidance on how exposure notification can complement traditional interventions to suppress the spread of COVID-19.

6.
Nat Commun ; 12(1): 726, 2021 02 09.
Artigo em Inglês | MEDLINE | ID: mdl-33563980

RESUMO

Human mobility is a primary driver of infectious disease spread. However, existing data is limited in availability, coverage, granularity, and timeliness. Data-driven forecasts of disease dynamics are crucial for decision-making by health officials and private citizens alike. In this work, we focus on a machine-learned anonymized mobility map (hereon referred to as AMM) aggregated over hundreds of millions of smartphones and evaluate its utility in forecasting epidemics. We factor AMM into a metapopulation model to retrospectively forecast influenza in the USA and Australia. We show that the AMM model performs on-par with those based on commuter surveys, which are sparsely available and expensive. We also compare it with gravity and radiation based models of mobility, and find that the radiation model's performance is quite similar to AMM and commuter flows. Additionally, we demonstrate our model's ability to predict disease spread even across state boundaries. Our work contributes towards developing timely infectious disease forecasting at a global scale using human mobility datasets expanding their applications in the area of infectious disease epidemiology.


Assuntos
Previsões/métodos , Influenza Humana/epidemiologia , Aprendizado de Máquina , Austrália/epidemiologia , Humanos , Influenza Humana/prevenção & controle , Influenza Humana/transmissão , Modelos Teóricos , Cidade de Nova Iorque/epidemiologia , Dinâmica Populacional , Reprodutibilidade dos Testes , Smartphone
7.
Nat Commun ; 10(1): 4817, 2019 10 23.
Artigo em Inglês | MEDLINE | ID: mdl-31645563

RESUMO

The recent trend of rapid urbanization makes it imperative to understand urban characteristics such as infrastructure, population distribution, jobs, and services that play a key role in urban livability and sustainability. A healthy debate exists on what constitutes optimal structure regarding livability in cities, interpolating, for instance, between mono- and poly-centric organization. Here anonymous and aggregated flows generated from three hundred million users, opted-in to Location History, are used to extract global Intra-urban trips. We develop a metric that allows us to classify cities and to establish a connection between mobility organization and key urban indicators. We demonstrate that cities with strong hierarchical mobility structure display an extensive use of public transport, higher levels of walkability, lower pollutant emissions per capita and better health indicators. Our framework outperforms previous metrics, is highly scalable and can be deployed with little cost, even in areas without resources for traditional data collection.

8.
Sci Adv ; 2(4): e1501748, 2016 04.
Artigo em Inglês | MEDLINE | ID: mdl-28861467

RESUMO

The angular momentum of light plays an important role in many areas, from optical trapping to quantum information. In the usual three-dimensional setting, the angular momentum quantum numbers of the photon are integers, in units of the Planck constant h. We show that, in reduced dimensions, photons can have a half-integer total angular momentum. We identify a new form of total angular momentum, carried by beams of light, comprising an unequal mixture of spin and orbital contributions. We demonstrate the half-integer quantization of this total angular momentum using noise measurements. We conclude that for light, as is known for electrons, reduced dimensionality allows new forms of quantization.


Assuntos
Modelos Teóricos , Pinças Ópticas , Fótons , Elétrons , Luz , Óptica e Fotônica , Teoria Quântica , Espalhamento de Radiação
9.
Opt Express ; 23(20): 26326-35, 2015 Oct 05.
Artigo em Inglês | MEDLINE | ID: mdl-26480146

RESUMO

We experimentally and numerically study near-field and far-field visible light scattering from lithographically defined micron scale dielectric particles. We demonstrate field confinement and elongated intensity features known as photonic nanojets in the Fresnel zone. An experimental setup is introduced which allows simultaneous mapping of the angular properties of the scattering in the Fresnel zone and far-field regions. Precise control over the shape, size and position of the scatterers, allows direction control of the near-field intensity distribution. Intensity features with 1/3 the divergence of free space Gaussian beams of similar waist are experimentally observed. Additionally the direction and polarization of the incident light can be used to switch on and off intensity hot spots in the near-field. Together these parameters allow a previously un-obtainable level of control over the intensity distribution in the near-field, compared to spherically and cylindrically symmetric scattering particles.

10.
Phys Rev Lett ; 111(23): 230403, 2013 Dec 06.
Artigo em Inglês | MEDLINE | ID: mdl-24476236

RESUMO

Observations of macroscopic quantum coherence in driven systems, e.g. polariton condensates, have strongly stimulated experimental as well as theoretical efforts during the last decade. We address the question of whether a driven quantum condensate is a superfluid, allowing for the effects of disorder and its nonequilibrium nature. We predict that for spatial dimensions d<4 the superfluid stiffness vanishes once the condensate exceeds a critical size, and treat in detail the case d=2. Thus a nonequilibrium condensate is not a superfluid in the thermodynamic limit, even for weak disorder, although superfluid behavior would persist in small systems.

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