[The clinical results and lipid peroxidation dynamics in the patients presenting with psoriasis treated by the applications of a natural highly mineralized bromine-iodine brine].

The authors report the results of the treatment of 64 patients presenting with psoriasis by the applications of a natural highly mineralized bromine-iodine brine. The method has been shown to be highly efficacious and safe. It allowed the clinical remission and marked improvement of the patients' clinical conditions to be achieved in 48 (77.4%) cases compared with 10 (27.8%) cases among the patients of the control group. Exacerbation was documented in a single patient with psoriatic erythrodermia. All the patients showed the normal results of general and biochemical clinical analyses of blood and urea throughout the study period. The applications of the natural highly mineralized bromine-iodine brine exerted the normalizing action on seven of the 8 characteristics of the lipid peroxidation process. It is maintained that the high effectiveness of the method in question can be accounted not only by the reflectory and humoral mechanisms of action of highly mineralized bromine-iodine brine but also by the marked exhaustion of the functional reserves of the mast cells under effect of the applications. It is concluded that an advantage of the proposed approach over standard balneotherapeutic procedures consists of the possibility to employ it not only at the base of a spa and health resort facility but also in a different setting with the involvement of the patients suffering from progressive psoriasis.

[The modern concepts of pyoderma gangrenosum].

The review provides an update on pyoderma ganrenosum, a rare chronic disease from a group of neutrophilic dermatoses. It considers its pathogenesis, its association with background visceral disease, and the specific features of skin and visceral involvement. Major and minor diagnostic criteria and differential treatment approaches are given.

[Complex evaluation of intestine microbiocenosis condition in patients with chronic pancreatitis].

AIM: Study the state of intestine microbiocenosis in patients with chronic pancreatitis, give comparative evaluation of diagnostic significance of bacterial and gas-liquid chromatography analysis. MATERIALS AND METHODS: 96 patients with chronic pancreatitis (CP) were examined bacteriologically for dysbacteriosis. In parallel in 42 individuals gas-liquid chromatography analysis (GLC-analysis) was carried out. RESULTS: During bacteriological examination in 93.7% of patients various dysbiotic disorders were detected. The main indicators of GLC-analysis---anaerobic index, cumulative content of volatile fatty acids and their isoforms also gave evidence on imbalance of intestine microflora. GLC-analysis as a rule confirmed the data of bacteriological examination. CONCLUSION: During parallel use ofbacteriological and gas-liquid chromatography analysis in almost all the CP patients intestine dysbacteriosis of various degree of intensity was detected. Combined use of these methods increases effectiveness of examination.

[The hygienic characteristic and effectiveness of the application of natural sylvinite screens for the combined treatment of the patients presenting with vulgar psoriasis].

The objective of the present study was to provide hygienic assessment of hospital wards equipped with the therapeutic sylvinite screens (TSS) and compare the results of the treatment of 80 patients suffering vulgar psoriasis with the use of TSS and without them. The sylvinite screens made it possible to create comfortable microenvironment in the wards and moderately increased the radiation background (0,15+/-0,005 Sv/hour) thereby promoting saturation of the ward atmosphere with aeroions dominated by the light negative particles (491,5+/-14,4 units/cm3). Such healthy environment hadc beneficial effect on the clinical course of the psoriatic process, the state of functional systems of the patients and their quality of life. It is concluded that the introduction of halotherapy in the treatment in patients presenting with vulgar psoriasis makes it possible to achieve clinical remission in 65% of them compared with 20% of the patients given the traditional treatment.

[A case of bullous-ulcerative lichen ruber planus]. / Sluchai bullezno-iazvennogo krasnogo ploskogo lishaia.

Bullous ulcerative lichen ruber planus (BULRP) in a 58-year-old woman is described. Besides the common symptoms (papular rash, vesicles and ulcers on the soles, detachment of the nail plates, atrophic foci on the hairy part of the head), the patient has developed erosions on the buccal and vaginal mucosa, articular involvement, complete loss of hair in the armpits and on the pubis. Local dibunol liniment has been effective in therapy of the mucosal erosions.

[Detection of immunological shifts with respect to Chlamydia in patients with urogenital pathology]. / Vyiavlenie immunologicheskikh sdvigov k khlamidiiam u bol'nykh s urogenital'noi patologii.

The possibility of using the complement fixation test and, mainly, the indirect hemagglutination test with the use of group-specific diagnostic reagents for the tentative serological detection of urogenital chlamydiasis has been studied. The indirect hemagglutination test has proved to be sufficiently informative. Further investigation aimed at the study of the sensitivity and specificity of this test in urogenital chlamydiasis are believed to be expedient and promising.