Epoxy resin-based root canal sealers: An integrative literature review.

The correct obturation of the root canal system achieved by means of a core and a cement is essential for the success of endodontic treatment. There are several root canal cements (RCCs) on the market; however, because of their excellent characteristics, epoxy resin-based sealers (ERBSs) have been widely used. The main aim of this review was to analyze and integrate the available information on different ERBSs. An electronic search was performed in the PubMed and Scopus databases, using "epoxy resin" AND "root canal treatment", and "epoxy resin" AND "endodontics" as search terms. In general, ERBSs have good flow properties, film thickness, solubility, dimensional stability, sealing capacity, and radiopacity. They are also able to adhere to dentin while exhibiting low toxicity and some antibacterial effects. However, their main disadvantage is the lack of bioactivity and biomineralization capability. A large number of ERBSs are available on the market, and AH Plus keeps being the gold standard RCC. Yet, information on many of them is limited or non-existent, which could be due to the fact that some of them are relatively new. The latter emphasizes the need for relevant research on the physicochemical and biological properties of some ERBSs, with the aim of supporting their clinical use with sufficient evidence via prospective and long-term studies.

Efecto antimicrobiano del cinamaldehído, timol, eugenol y quitosano sobre cepas de Streptococcus mutans / Antimicrobial effect of cinnamaldehyde, thymol, eugenol and chitosan on Streptococcus mutans strains

Objetivo: evaluar la actividad antimicrobiana de cinamaldehído, timol, eugenol y quitosano en comparación con clorhexidina al 0,12 por ciento sobre cepas de Streptococccus mutans. Métodos: se realizaron pruebas de susceptibilidad bacteriana de cepas de Streptococccus mutans con discos embebidos en eugenol, cinamaldehído, quitosano y timol, al 0,1 y 1 por ciento con un control positivo de clorhexidina al 0,12 por ciento evaluando los halos de inhibición existentes a las 24 h y 48 h. Resultados: el cinamaldehído al 1 por ciento mostró el mejor poder de control sobre el crecimiento de Streptococccus mutans al presentar 19,91 mm y 24,44 mm de halos de inhibición a las 24 h y 48 h, respectivamente, con una diferencia significativa de p< 0,05 entre los dos intervalos. Cuando se comparó el cinamaldehído al 1 por ciento con el control positivo de clorhexidina al 0,12 por ciento, no se encontraron diferencias significativas (p> 0,05). Conclusiones: el cinamaldehído al 1 por ciento tuvo los mejores resultados seguidos por quitosano, eugenol y timol a la misma concentración en comparación con clorhexidina al 0,12 por ciento tanto a la 24 como 48 h(AU)

Objective: to evaluate the antimicrobial activity of cinnamaldehyde, thymol, eugenol and chitosan compared to chlorhexidine-0.12 percent on Streptococcus mutans strains. Methods: bacterial susceptibility tests were performed on S. mutans strains with disks embedded in eugenol, cinnamaldehyde, chitosan and thymol, at 0.1 percent and 1 percent with a positive control of 0.12 percent chlorhexidine, evaluating existing inhibition zones after 24 and 48 hours. Results: cinnamaldehyde-1 percent showed the best control power over the growth of S. mutans, presenting 19.91 mm and 24.44 mm of inhibition halos after 24 and 48 hours, respectively, with a significant difference of p< 0.05 between the two intervals. When the cinnamaldehyde-1 percent was compared with the positive control of chlorhexidine-0.12 percent, no significant differences were found (p> 0.05). Conclusions: cinnamaldehyde-1 percent had the best results followed by chitosan, eugenol and thymol in the same concentration compared to chlorhexidine-0.12 percent after both 24 and 48 hours(AU)