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1.
J Hip Preserv Surg ; 11(2): 150-155, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-39070205

RESUMO

The coronavirus disease 2019 pandemic has significantly affected people worldwide. Herein, we present a case of massive heterotopic ossification (HO) of the right hip following severe SARS-CoV-2 infection. The exact origin of HO development is still unknown, but a critical illness, chronic immobilization and hypoxia are important risk factors. Considering the location and size of the HOs in this case, modified Ludloff's medial approach of the hip was used. This approach allows for good exposure and access to the medial and inferior part of the hip joint and the successful extirpation of the pathologic tissue.

2.
J Pers Med ; 13(9)2023 Aug 25.
Artigo em Inglês | MEDLINE | ID: mdl-37763067

RESUMO

Vitamin C, a potent reducing and antioxidant agent, plays an important role in the body, aiding in the growth of cartilage and bones. It is also involved in mechanisms that help reduce inflammation and its effects on the body. In addition, vitamin C decreases pro-inflammatory cytokines, such as IL-6, which produce acute-phase proteins such as CRP and influence inflammatory markers such as ESR. We carried out a study with 110 patients who underwent total knee replacement surgery. We divided the patients into two groups, in which the intervention group received 15 g of parenteral vitamin C during the immediate postoperative period while the control group did not. Patients who received 15 g of vitamin C after total knee replacement surgery had decreased inflammatory markers, specifically CRP and ESR. Overall, administering vitamin C in the post-surgical period results in improved management of inflammation, as evidenced by a decrease in CRP and ESR values. This leads to faster recovery and better healing outcomes for patients undergoing total knee replacement surgery. Furthermore, the beneficial effects of vitamin C in reducing proinflammatory cytokines, reducing the need for opioid analgesics, and its mild adverse effects make it a promising adjuvant in managing postoperative recovery.

3.
J Sport Rehabil ; 32(3): 289-295, 2023 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-36535272

RESUMO

CONTEXT: Professional athletes showed excellent results after hip preserving procedures. However, there is still a lack of knowledge regarding the rate of return to activity and the rehabilitation time of recreational athletes. Thus, the aim of this study was to investigate factors that were associated with an extended return-to-activity time in nonprofessional athletes. DESIGN: Retrospective, quantitative case-control study. METHODS: This study included 47 cases (45 nonprofessional athletes), which were divided according to return-to-activity time (short term: 0.0-7.0 mo vs long term: >7.0 mo). The clinical outcome were evaluated with the modified Harris hip score, the nonarthritic hip score, the Western Ontario and McMaster Universities Osteoarthritis Index, and the University of California, Los Angeles activity score. For statistical analysis between both groups, an unpaired student t test and a paired Wilcoxon test were used. In addition, the sports behavior, intraoperative findings, and surgical procedures were also assessed. RESULTS: After a mean follow-up of 4.3 years (±0.6; 3.4-5.6), the overall postoperative modified Harris hip score was 81.8 points, the nonarthritic hip score was 75.8 points, the Western Ontario and McMaster Universities Osteoarthritis Index was 36.7 points, and the University of California, Los Angeles activity score was 7.9. Compared with the preoperative results, all scores improved significantly (P < .001). Patients of the short-term return-to-activity group showed a higher preoperative activity diversity and, postoperatively, a higher rate in high-impact sports (P = .024). CONCLUSIONS: After mini-open arthrotomy for femoroacetabular impingement syndrome treatment, 92.5% of the recreational athletes returned to sports activity. The findings did not detect factors influencing the return-to-activity time. However, a higher preoperative diversity of activities and a shift to high-level impact sport activities might support a shorter rehabilitation.


Assuntos
Impacto Femoroacetabular , Osteoartrite , Humanos , Impacto Femoroacetabular/reabilitação , Articulação do Quadril/cirurgia , Estudos Retrospectivos , Estudos de Casos e Controles , Volta ao Esporte , Artroscopia/métodos , Atletas , Hábitos , Resultado do Tratamento , Seguimentos
4.
Z Orthop Unfall ; 161(1): 57-64, 2023 Feb.
Artigo em Inglês, Alemão | MEDLINE | ID: mdl-35189656

RESUMO

The Working Group of the German Orthopedic and Trauma Society (DGOU) on Tissue Regeneration has published recommendations on the indication of different surgical approaches for treatment of full-thickness cartilage defects in the knee joint in 2004, 2013 and 2016. Based upon new scientific knowledge and new developments, this recommendation is an update based upon the best clinical evidence available. In addition to prospective randomised controlled clinical trials, this also includes studies with a lower level of evidence. In the absence of evidence, the decision is based on a consensus process within the members of the working group.The principle of making decision dependent on defect size has not been changed in the new recommendation either. The indication for arthroscopic microfracturing has been reduced up to a defect size of 2 cm2 maximum, while autologous chondrocyte implantation is the method of choice for larger cartilage defects. Additionally, matrix-augmented bone marrow stimulation (mBMS) has been included in the recommendation for defects ranging from 1 to 4.5 cm2. For the treatment of smaller osteochondral defects, in addition to osteochondral transplantation (OCT), mBMS is also recommended. For larger defects, matrix-augmented autologous chondrocyte implantation (mACI/mACT) in combination with augmentation of the subchondral bone is recommended.


Assuntos
Doenças das Cartilagens , Cartilagem Articular , Procedimentos Ortopédicos , Ortopedia , Humanos , Estudos Prospectivos , Doenças das Cartilagens/cirurgia , Articulação do Joelho/cirurgia , Condrócitos , Cartilagem Articular/cirurgia , Cartilagem Articular/lesões
6.
Orthopadie (Heidelb) ; 51(6): 483-493, 2022 Jun.
Artigo em Alemão | MEDLINE | ID: mdl-35925373

RESUMO

BACKGROUND: Femoroacetabular impingement syndrome (FAIS) has gained vast importance in the last two decades. Multiple studies have shown that if untreated, early osteoarthritis of the hip joint may result. Hip arthroscopy is one of the fastest growing procedures in the orthopedic cosmos, having already replaced the majority of (mini) open techniques in FAIS surgery. However, with the recent remarkable increase in the volume of hip arthroscopies performed worldwide, the number of patients with persistent or recurrent symptoms after FAIS surgery is also growing. PATHOLOGY: Potential underlying pathologies are misresection of the bony deformity, insufficiency fracture of the femoral head neck junction or the femoral subchondral head itself (SIFFH), adhesions, failed chondrolabral or capsular treatment, septic arthritis, heterotopic ossification or a wrong indication in the case of osteoarthritis that is already too advanced. Most of these occur more often during the extensive learning curve for hip arthroscopy. DIAGNOSTICS: High-quality imaging plays a key role in determining the need for revision surgery vs. further conservative treatment. Therapeutical avenues are shown with the common goal of proper detection and correction of the underlying pathology to address unsatisfactory FAIS treatment outcomes and ensure long-term survival of the native hip joint.


Assuntos
Impacto Femoroacetabular , Artroscopia/métodos , Impacto Femoroacetabular/diagnóstico , Cabeça do Fêmur , Articulação do Quadril/diagnóstico por imagem , Humanos , Reoperação
7.
Orthopadie (Heidelb) ; 51(6): 466-471, 2022 Jun.
Artigo em Alemão | MEDLINE | ID: mdl-35482052

RESUMO

The prevalence of femoroacetabular impingement syndrome in professional soccer athletes is high. Professional training and treatment conditions ensure an effective conservative therapy focusing on dynamic stability, motion control, muscle balance and core stability. In the case of persistent limitations, indication for surgery has to be considered carefully. The probability is high that return to a professional level of soccer is feasible. However, the period of rehabilitation is long, leading to a potential conflict area between economic and medical interests. Good communication and intensive patient education are essential.


Assuntos
Impacto Femoroacetabular , Futebol , Artroscopia , Atletas , Impacto Femoroacetabular/epidemiologia , Humanos , Volta ao Esporte
8.
Orthopade ; 51(3): 167-175, 2022 Mar.
Artigo em Alemão | MEDLINE | ID: mdl-35113212

RESUMO

During the last two decades femoroacetabular impingement syndrome (FAIS) has gained importance and is one of the main causes of hip pain in young adults. FAIS is a motion-related clinical pathology of the hip that represents symptomatic contact between the proximal femur and the acetabulum. Symptoms, clinical signs, and imaging findings must be present to diagnose FAIS. Especially the development of the cam-FAIS seems to be associated with an overuse of the growth plate during adolescence. Here an approach may be found for the prevention of the development of FAIS. Sufficient evidence through high-quality long-term results is yet lacking.


Assuntos
Impacto Femoroacetabular , Acetábulo , Adolescente , Artralgia/diagnóstico , Artralgia/epidemiologia , Artralgia/etiologia , Artroscopia , Impacto Femoroacetabular/diagnóstico por imagem , Impacto Femoroacetabular/epidemiologia , Quadril , Articulação do Quadril/diagnóstico por imagem , Humanos , Adulto Jovem
9.
Int Orthop ; 46(2): 205-214, 2022 02.
Artigo em Inglês | MEDLINE | ID: mdl-34410478

RESUMO

PURPOSE: The purpose of this study was to analyze predicting factors for a conversion to a total hip replacement (THR) after mini-open arthrotomy for treatment of femoroacetabular impingement (FAI). METHODS: Between 2011 and 2016, we identified 32 patients, who were treated for FAI with a mini-open arthrotomy and received after mean time of 2.1 ± 1.4 years a THR. These patients were compared to 47 cases who did not receive a THR (mean follow-up: 4.3 ± 0.7 years) to explore pre- and intra-operative factors associated with a conversion to THR. The results were presented in separated Kaplan-Meier curves with log rank test for significance and hazard ratios. RESULTS: A lateral joint space width of > 4 mm showed a higher THR-free survival rate compared to < 4 mm (p = 0.001); analogously one-sided (acetabular/femoral) 3-4° cartilage damage had a comparable THR-free survival rate than 1-2° kissing lesions (p = 0.001). Furthermore, an intact labrum without treatment and good cartilage status, a refixed labrum after rim resection in case of a pincer type FAI, or a refixed teared labrum were associated with a longer THR-free time than an untreated labrum accompanied by a poor cartilage status or an ossified labrum (p = 0.002). The strongest independent factor for a conversion to THR was femoral cartilage damage grade 1 and higher (p = 0.046). However, the rate of available patients was 53.0%. CONCLUSION: The success of a joint-preserving mini-open arthrotomy seems to be dependent on the status of the radiological joint space width and the intra-operative cartilage status of the lateral edge.


Assuntos
Artroplastia de Quadril , Impacto Femoroacetabular , Acetábulo/cirurgia , Artroplastia de Quadril/efeitos adversos , Artroscopia , Impacto Femoroacetabular/complicações , Impacto Femoroacetabular/diagnóstico por imagem , Impacto Femoroacetabular/cirurgia , Articulação do Quadril/diagnóstico por imagem , Articulação do Quadril/patologia , Articulação do Quadril/cirurgia , Humanos , Prognóstico , Resultado do Tratamento
10.
Physiother Res Int ; 25(4): e1869, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32985036

RESUMO

BACKGROUND AND PURPOSE: There is an ongoing controversy in respect of the usage of continuous passive motion (CPM) following total knee arthroplasty (TKA). We analysed the impact of CPM on the early rehabilitation after TKA and the clinical outcome over the time. METHODS: Forty patients were prospectively randomized to postoperative protocols following TKA. Half of them (n = 20) received the standard manual therapy alone and the others (n = 20) were treated additionally with CPM. Identical implants were used in all patients. Passive range of movement (PROM) was noted. Patient satisfaction and knee function was evaluated using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) as well as the Knee Society Score (KSS) at time of discharge and 2 years postoperatively. RESULTS: The patients in the solitary manual therapy group (MT) showed preoperatively a 7.2° greater PROM (p = .03) with 5.4° higher flexion (p = .05). Analogously, the KSS presented with 42.7 points a higher score result compared to the CPM group with 35.9 points (p = .03). Although the preoperative ability with 105.2° for flexion and 97.2° for the PROM were in favour of the group without CPM (99.8° resp. 90.0°), at time of discharge the patients with CPM reached with 111.0° a significant higher flexion and with 109.0° a higher PROM (MT group: 107.0° resp. 103.5°) (p = .04/.02). At 2 years follow-up both scores (WOMAC/KSS) and function (extension, flexion and PROM) were balanced (p > .05). Patella resurfacing showed no impact on the clinical results at discharge or at time of last follow-up (p > .05). DISCUSSION: Although the addition of CPM did significantly improve knee flexion in the early postoperative stage, the difference might not represent a clinical relevance. Further, there were no notable effects on long-term clinical and functional results following TKA, so the routine application of CPM in the above stated setting might be ceased.


Assuntos
Artroplastia do Joelho/reabilitação , Terapia Passiva Contínua de Movimento/métodos , Osteoartrite do Joelho/reabilitação , Amplitude de Movimento Articular/fisiologia , Atividades Cotidianas , Idoso , Terapia por Exercício/métodos , Feminino , Humanos , Articulação do Joelho/fisiopatologia , Masculino , Pessoa de Meia-Idade , Período Pós-Operatório , Índice de Gravidade de Doença , Resultado do Tratamento
11.
J Orthop ; 21: 10-13, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32071526

RESUMO

INTRODUCTION: Since less invasive approaches for total hip arthroplasty (THA) are promoted, our aim was to compare direct lateral (DLA) and anterolateral approach (ALA) under otherwise identical conditions. METHODS: Pre - and postoperative x-rays from 200 propensity matched patients (DLA vs. ALA) were evaluated for anatomical reconstruction. RESULTS: Overall, the cup position was within the safe zone in both group while the mean center of rotation (COR) was placed more medial and cranial in both groups compared to preoperative anatomy (p > 0.05). The mean leg elongation was comparable between both approaches (p > 0.05). Postoperatively the WOMAC improved about 90%. CONCLUSION: This study confirmed that the ALA can be safely used for THA in minimal invasive setting.

12.
Int Orthop ; 41(10): 2001-2008, 2017 10.
Artigo em Inglês | MEDLINE | ID: mdl-28819826

RESUMO

PURPOSE: Local cartilage and bony defects, which are too large for joint preserving cartilage treatment are difficult to treat. The implantation of a mini-resurfacing implant (Hemicap®, 2med, Hamburg, Germany) may be a possible alternative treatment for these patients. This partial replacement fills the defect and restores a smooth and continuous articular surface. The aim of this study was to determine short- to midterm results of the treatment of local cartilage defects of the femoral head using the Hemicap®. METHODS: Since 04/2011 16 patients with osteonecrosis of the femoral head greater ARCO stage II or local femoral cartilage lesions (< 35 mm) were treated with the implantation of the Hemicap® implant. A clinical and radiological follow-up was conducted. RESULTS: The clinical results showed a significant improvement of the function and pain of the hip according to the Harris Hip Score from 56 (±14) preoperative to 77 (±15) post-operative 25 months after implantation of the Hemicap®. In the meantime, in four patients the Hemicap® had to be converted to a total hip arthroplasty due to loosening, progredience of the osteonecrosis or degeneration of the acetabulum. CONCLUSIONS: The implantation of the mini-resurfacing implant Hemicap® seemed to be an alternative treatment for local cartilage defects of the femoral head to postpone the implantation of a total hip arthroplasty. However, the clinical outcome seems to be inferior to total hip arthroplasty. Furthermore, due to a high rate of conversion to total hip arthroplasty (25%) the application of this implant is questionable. If the implant is considered as a treatment option at least patient selection and enlightenment for this treatment with the high risk of failure and progression of osteoarthritis is very important.


Assuntos
Artroplastia de Quadril/métodos , Cabeça do Fêmur/cirurgia , Prótese de Quadril/efeitos adversos , Osteonecrose/cirurgia , Adolescente , Adulto , Artroplastia de Quadril/efeitos adversos , Feminino , Articulação do Quadril/fisiopatologia , Articulação do Quadril/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Medição da Dor , Amplitude de Movimento Articular , Estudos Retrospectivos , Taxa de Sobrevida , Resultado do Tratamento , Adulto Jovem
13.
Orthop Rev (Pavia) ; 8(2): 6445, 2016 Jun 27.
Artigo em Inglês | MEDLINE | ID: mdl-27433303

RESUMO

Magnesium-based interference screws may be an alternative in anterior/posterior cruciate ligament reconstruction. The well-known osteoconductive effects of biodegradable magnesium alloys may be useful. It was the purpose of this study to evaluate the biomechanical properties of a magnesium based interference screw and compare it to a standard implant. A MgYREZr-alloy interference screw and a standard implant (Milagro®; De Puy Mitek, Raynham, MA, USA) were used for graft fixation. Specimens were placed into a tensile loading fixation of a servohydraulic testing machine. Biomechanical analysis included pretensioning of the constructs at 20 N for 1 min following cyclic pretensioning of 20 cycles between 20 and 60 N. Biomechanical elongation was evaluated with cyclic loading of 1000 cycles between 50 and 200 N at 0.5 Hz. Maximum load to failure was 511.3±66.5 N for the Milagro® screw and 529.0±63.3 N for magnesium-based screw (ns, P=0.57). Elongations after preload, during cyclical loading and during failure load were not different between the groups (ns, P>0.05). Stiffness was 121.1±13.8 N/mm for the magnesium-based screw and 144.1±18.4 for the Milagro® screw (ns, P=0.32). MgYREZr alloy interference screws show comparable results in biomechanical testing to standard implants and may be an alternative for anterior cruciate reconstruction in the future.

14.
Hip Int ; 26 Suppl 1: 38-42, 2016 May 14.
Artigo em Inglês | MEDLINE | ID: mdl-27174063

RESUMO

INTRODUCTION: Femoroacetabular impingement (FAI) has been proposed as a possible cause of early osteoarthritis of the hip. The treatment of this condition and its related lesions can be performed by 3 methods: surgical dislocation of the hip; pure arthroscopic; and anterior mini-open technique with or without arthroscopic assistance. METHODS: We describe the anterior mini-open technique and report our experience over the last decade in the treatment of FAI and different associated pathologies of the hip. RESULTS: This technique was found to be safe and reliable, allowing tissue preservation and providing a clinical improvement similar to the purely arthroscopic-treated patient, even in complex cases. DISCUSSIONS: According to our experience there are several presentations of FAI and associated hip conditions, where other authors advocate surgical dislocation, which can be conducted through a mini-open approach when increased surgical skills are reached. Moreover, this technique was found to be useful as an additional tool to consider, even for surgeons involved in the arthroscopic learning curve.


Assuntos
Artroscopia/métodos , Impacto Femoroacetabular/cirurgia , Amplitude de Movimento Articular/fisiologia , Estudos de Coortes , Feminino , Impacto Femoroacetabular/diagnóstico por imagem , Humanos , Masculino , Procedimentos Cirúrgicos Minimamente Invasivos/métodos , Medição da Dor , Prognóstico , Recuperação de Função Fisiológica , Estudos Retrospectivos , Medição de Risco , Índice de Gravidade de Doença , Tomografia Computadorizada por Raios X/métodos , Resultado do Tratamento
15.
Technol Health Care ; 2016 Mar 18.
Artigo em Inglês | MEDLINE | ID: mdl-27002474

RESUMO

BACKGROUND: Short-stem implants are routinely used for total hip arthroplasty in younger patients that are more likely to have secondary osteoarthritis than older patients. OBJECTIVE: To investigate the applicability of short-stem hip implants for secondary osteoarthritis due to developmental dysplasia of the hip. METHODS: This study analyzed the clinical and radiological results of patients with developmental dysplasia of the hip (DDH, 58 hips) and compared them to those of patients with primary osteoarthritis (POA, 59 hips) treated with the metaphyseal total hip arthroplasty (Metha®) short stem with metaphyseal fixation. RESULTS: The mean clinical and radiological follow-up periods were 2.9 ± 1.1 years and 3.8 ± 1.9 years, respectively. The mean Harris Hip Score (HHS) significantly increased in both groups over this period (p< 0.0001). The caput-collum-diaphysis (CCD) angle was significantly lower in the POA group prior to surgery and significantly increased in the POA and and decreased in DDH groups, respectively. The preoperative femoral offset was lower in the DDH group and increased significantly after surgery. CONCLUSIONS: The Metha® short stem in patients with DDH allows good reconstruction of joint biomechanics with a good clinical outcome.

16.
Technol Health Care ; 24(3): 359-65, 2016 May 18.
Artigo em Inglês | MEDLINE | ID: mdl-26757442

RESUMO

BACKGROUND: Surgical treatment of femoroacetabular impingement is becoming accepted worldwide, owing to improvements in clinical results and quality of life. In addition to treatment by surgical dislocation or arthroscopy, arthroscopic assisted mini-open approach was postulated to treat this pathology. OBJECTIVE: The aim of this study was to analyze early results of the first consecutive 72 cases of femoroacetabular impingement treated using the arthroscopic assisted mini-open approach in two different centers by two surgeons trained by a senior surgeon experienced in the technique. METHODS: Seventy-two consecutive cases of femoroacetabular impingement were operated in arthroscopic assisted mini-open approach technique in two different centers. After a mean follow-up time of 15 months (range 6-24 months), the Western Ontario and McMaster Universities Arthritis Index, Hip disability and Osteoarthritis Outcome Score and University of California, Los Angeles activity score, alpha angle and Wiberg angle were obtained. RESULTS: In both centers, all three scores showed significantly better results at follow-up time than preoperatively. The Western Ontario and McMaster Universities Arthritis Index increased from 64.3 to 91.4 (A) and from 68.1 to 89 (B). The Hip disability and Osteoarthritis Outcome Score increased from 59.5 to 94.4 (A) and from 62.1 to 93.8 (B). The University of California, Los Angeles activity score increased from 5.2 to 8.1 (A) and from 5.3 to 8.4 (B). The alpha angle and the Wiberg angle were significantly reduced after osteoplasty. The overall complication rate was low. CONCLUSIONS: Early results of this study show a good clinical and radiological outcome; therefore, the arthroscopic assisted mini-open approach can be used as an alternative in treating femoroacetabular impingement.


Assuntos
Artroscopia/métodos , Impacto Femoroacetabular/cirurgia , Adolescente , Adulto , Idoso , Feminino , Impacto Femoroacetabular/reabilitação , Humanos , Masculino , Pessoa de Meia-Idade , Duração da Cirurgia , Complicações Pós-Operatórias/epidemiologia , Amplitude de Movimento Articular , Adulto Jovem
17.
Knee Surg Sports Traumatol Arthrosc ; 24(12): 3976-3981, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-25246174

RESUMO

PURPOSE: Degradable magnesium implants have received increasing interest in recent years. In anterior cruciate ligament reconstruction surgery, the well-known osteoconductive effects of biodegradable magnesium alloys may be useful. The aim of this study was to examine whether interference screws made of MgYREZr have comparable biomechanical properties to commonly used biodegradable screws and whether a different thread on the magnesium screw has an influence on the fixation strength. METHODS: Five magnesium (MgYREZr-alloy) screws were tested per group. Three different groups with variable thread designs (Designs 1, 2, and 3) were produced and compared with the commercially available bioabsorbable Bioacryl rapid polylactic-co-glycolic acid screw Milagro®. In vitro testing was performed in synthetic bone using artificial ligament fixed by an interference screw. The constructs were pretensioned with a constant load of 60 N for 30 s followed by 500 cycles between 60 N and 250 N at 1 Hz. Construct displacements between the 1st and 20th and the 21st and 500th cycles were recorded. After a 30 s break, a maximum load to failure test was performed at 1 mm/s measuring the maximum pull-out force. RESULTS: The maximum loads to failure of all three types of magnesium interference screws (Design 1: 1,092 ± 133.7 N; Design 2: 1,014 ± 103.3 N; Design 3: 1,001 ± 124 N) were significantly larger than that of the bioabsorbable Milagro® interference screw (786.8 ± 62.5 N) (p < 0.05). However, the greatest maximum load was found with magnesium screw Design 1. Except for a significant difference between Designs 1 and 2, there were no further significant differences among the four groups in displacement after the 20th cycle. CONCLUSIONS: Biomechanical testing showed higher pull-out forces for magnesium compared with a commercial polymer screw. Hence, they suggest better stability and are a potential alternative. The thread geometry does not significantly influence the stability provided by the magnesium implants. This study shows the first promising results of a degradable material, which may be a clinical alternative in the future.


Assuntos
Implantes Absorvíveis , Ligas , Parafusos Ósseos , Magnésio , Ligamento Cruzado Anterior/cirurgia , Reconstrução do Ligamento Cruzado Anterior/instrumentação , Fenômenos Biomecânicos , Humanos , Ácido Láctico , Ácido Poliglicólico , Copolímero de Ácido Poliláctico e Ácido Poliglicólico
18.
Mater Sci Eng C Mater Biol Appl ; 59: 1100-1109, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26652469

RESUMO

The reconstruction of the anterior cruciate ligament is, for the most part, currently performed with interference screws made of titanium or degradable polymers. The aim of this study was to investigate the use of biodegradable magnesium interference screws for such a procedure because of their known biocompatibility and reported osteoconductive effects. The left tibiae of each of 18 rabbits were implanted with a magnesium-based (MgYREZr-alloy) screw, and another 18 with a titanium-based control. Each group was divided into observation periods of 4, 12 and 24weeks. After sacrifice, µCT scans were acquired to assess the amount of the gas liberated and the degradation rate of the implant. Histological evaluations were performed to investigate the local tissue response adjacent to the implant and to assess the status of the attachment between the tendon and the bone tissue. The µCT scans showed that liberation of gas was most prominent 4weeks after implantation and was significantly decreased by 24weeks. All screws remained in situ and formed a sufficient connection with the tendon and sufficient osseous integration at 24weeks. Histological evaluations showed neither inflammatory reactions nor necrosis of the tendon. The results of this pilot study in rabbits indicate that this magnesium-based interference screw should be considered as an alternative to conventional implant materials.


Assuntos
Reconstrução do Ligamento Cruzado Anterior/instrumentação , Materiais Biocompatíveis , Parafusos Ósseos , Magnésio , Animais , Ligamento Cruzado Anterior/cirurgia , Materiais Biocompatíveis/farmacologia , Materiais Biocompatíveis/uso terapêutico , Remodelação Óssea/efeitos dos fármacos , Feminino , Magnésio/farmacologia , Magnésio/uso terapêutico , Coelhos
19.
Arch Orthop Trauma Surg ; 135(7): 1003-10, 2015 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-25953630

RESUMO

INTRODUCTION: To analyze magnetic resonance imaging (MRI) at 3T and the clinical outcome in a short-term pilot study after treatment of retropatellar cartilage defects with microfracturing and subsequent covering with the cell-free chondrotissue(®) polyglycolic acid-hyaluronan implant. METHODS: Five consecutive patients after microfracturing and defect coverage with the chondrotissue(®) implant immersed with autologous serum were included. After a mean follow-up of 21 months (range 11-31 months), defect fill and repair tissue quality was assessed by 3-T MRI followed by applying established MRI scoring systems. The patients' situation was assessed using the Knee injury and Osteoarthritis Outcome Score (KOOS) and a patients' satisfaction questionnaire. RESULTS: Magnetic resonance imaging showed good to excellent defect fill with complete integration. The mean MOCART score was 61 (range 50-75) points. The mean Henderson score was 7 (range 6-9) points. All patients showed subchondral bone alterations. The KOOS showed good values in all sub-categories in 4 out of 5 patients and a mean overall score of 73 (range 40-90) points. Two patients rated the outcome as excellent, two as good and one as fair. All patients would have the procedure again and recommend it. CONCLUSIONS: In this small case series, the coverage of symptomatic retropatellar cartilage defects with the chondrotissue(®) implant after microfracturing was safe and feasible with improvement of the patients' situation at short-term follow-up. LEVEL OF EVIDENCE: IV, case series.


Assuntos
Artroplastia Subcondral/instrumentação , Doenças das Cartilagens/cirurgia , Cartilagem Articular/lesões , Traumatismos do Joelho/cirurgia , Prótese do Joelho , Osteoartrite do Joelho/cirurgia , Adolescente , Adulto , Artroplastia Subcondral/métodos , Doenças das Cartilagens/patologia , Cartilagem Articular/patologia , Cartilagem Articular/cirurgia , Materiais Revestidos Biocompatíveis , Feminino , Humanos , Ácido Hialurônico , Escala de Gravidade do Ferimento , Traumatismos do Joelho/patologia , Imageamento por Ressonância Magnética/métodos , Masculino , Osteoartrite do Joelho/patologia , Projetos Piloto , Ácido Poliglicólico , Índice de Gravidade de Doença , Transplante Autólogo , Resultado do Tratamento , Cicatrização , Adulto Jovem
20.
Am J Sports Med ; 43(3): 715-20, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25540294

RESUMO

BACKGROUND: Pelvic osteotomies are performed to prevent the progression of osteoarthritis and its associated pain due to adult hip dysplasia, particularly for young patients with no or low-grade osteoarthritis. No data are available concerning levels of sporting activity before and after triple pelvic osteotomy (TPO). Therefore, the aim of this study was to provide comprehensive data on levels of sporting activity and the subjective outcome of patients after this complex operation. HYPOTHESIS: Patients can return to a higher level of sports activity after TPO compared with their preoperative level. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: Between 2003 and 2011, a total of 116 triple pelvic osteotomies were performed at a single institution; the Tönnis and Kalchschmidt technique was used on 91 patients. After exclusion criteria for this study were applied, 77 patients remained (59 females and 18 males); the mean ± SD age at operation was 26 ± 3.9 years. To study outcomes, patients were asked to complete both the Harris hip score (HHS) and the Hip disability and Osteoarthritis Outcome Score (HOOS) preoperatively and at postoperative follow-up. Their level of activity was determined according to the University of California, Los Angeles (UCLA) activity score. Patients rated their hip movement and overall satisfaction preoperatively and at postoperative follow-up using a visual analog scale for sporting activity, physical fitness level, and level of pain experienced while performing their sport. RESULTS: The mean ± SD follow-up time was 6.2 ± 1.4 years. The mean HHS changed significantly from 63.3 ± 15.6 preoperatively to 90.1 ± 10.8 at follow-up (P < .001), and the mean HOOS changed significantly from 52.9 ± 20.1 to 82 ± 17.1 at follow-up (P < .001). The mean UCLA activity score changed significantly from 4.8 ± 2.1 to 7.7 ± 1.4 at follow-up (P < .001). CONCLUSION: Patients achieved a higher level of sports activity postoperatively. The postoperative level of participation in sports was superior, with a shift from low- to high-impact activities.


Assuntos
Luxação Congênita de Quadril/cirurgia , Osteoartrite do Quadril/prevenção & controle , Osteotomia/métodos , Ossos Pélvicos/cirurgia , Esportes , Adolescente , Adulto , Artralgia/etiologia , Artralgia/cirurgia , Progressão da Doença , Feminino , Seguimentos , Luxação Congênita de Quadril/complicações , Humanos , Masculino , Osteoartrite do Quadril/etiologia , Osteotomia/efeitos adversos , Medição da Dor , Período Pós-Operatório , Adulto Jovem
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