RESUMO
A consensus needs to be reached on a rational approach to infertile men with varicocele-associated nonobstructive azoospermia. Future studies are warranted to understand the mechanism behind the variable influence of varicocele on testicular function, which causes partial or complete damage of spermatogenesis in some cases and leaves it unaltered in others.
Assuntos
Azoospermia/etiologia , Azoospermia/terapia , Varicocele/complicações , Varicocele/terapia , Azoospermia/patologia , Azoospermia/reabilitação , Biópsia , Consenso , Humanos , Infertilidade Masculina/etiologia , Infertilidade Masculina/patologia , Infertilidade Masculina/terapia , Masculino , Valor Preditivo dos Testes , Racionalização , Espermatogênese/fisiologia , Varicocele/patologia , Varicocele/reabilitaçãoRESUMO
In azoospermic infertile men with varicocele, testicular biopsy revealed histopathologic patterns that varied from disorganized spermatogenesis with low or moderate sperm scores to early (primary spermatocytes stage) or late (spermatid stage) arrested spermatogenesis or germ cell aplasia and Sertoli cells only. Diagnostic testicular biopsy can be helpful for accurate management of azoospermic infertile men with varicoceles before surgical repair.