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1.
BMC Public Health ; 24(1): 2266, 2024 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-39169305

RESUMO

BACKGROUND: Chatbots can provide immediate assistance tailored to patients' needs, making them suitable for sustained accompanying interventions. Nevertheless, there is currently no evidence regarding their acceptability by hypertensive patients and the factors influencing the acceptability in the real-world. Existing evaluation scales often focus solely on the technology itself, overlooking the patients' perspective. Utilizing mixed methods can offer a more comprehensive exploration of influencing factors, laying the groundwork for the future integration of artificial intelligence in chronic disease management practices. METHODS: The mixed methods will provide a holistic view to understand the effectiveness and acceptability of the intervention. Participants will either receive the standard primary health care or obtain a chatbot speaker. The speaker can provide timely reminders, on-demand consultations, personalized data recording, knowledge broadcasts, as well as entertainment features such as telling jokes. The quantitative part will be conducted as a quasi-randomized controlled trial in community in Beijing. And the convergent design will be adopted. When patients use the speaker for 1 month, scales will be used to measure patients' intention to use the speaker. At the same time, semi-structured interviews will be conducted to explore patients' feelings and influencing factors of using speakers. Data on socio-demography, physical examination, blood pressure, acceptability and self-management behavior will be collected at baseline, as well as 1,3,6, and 12 months later. Furthermore, the cloud database will continuously collect patients' interactions with the speaker. The primary outcome is the efficacy of the chatbot on blood pressure control. The secondary outcome includes the acceptability of the chatbot speaker and the changes of self-management behavior. DISCUSSION: Artificial intelligence-based chatbot speaker not only caters to patients' self-management needs at home but also effectively organizes intricate and detailed knowledge system for patients with hypertension through a knowledge graph. Patients can promptly access information that aligns with their specific requirements, promoting proactive self-management and playing a crucial role in disease management. This study will serve as a foundation for the application of artificial intelligence technology in chronic disease management, paving the way for further exploration on enhancing the communicative impact of artificial intelligence technology. TRIAL REGISTRATION: Biomedical Ethics Committee of Peking University: IRB00001052-21106, 2021/10/14; Clinical Trials: ChiCTR2100050578, 2021/08/29.


Assuntos
Inteligência Artificial , Hipertensão , Humanos , Hipertensão/terapia , Feminino , China , Masculino , Adulto , Pessoa de Meia-Idade , Aceitação pelo Paciente de Cuidados de Saúde/psicologia , Atenção Primária à Saúde , Pesquisa Qualitativa
2.
J Allergy Clin Immunol Pract ; 12(8): 2066-2073, 2024 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-38631523

RESUMO

BACKGROUND: The prevalence of asthma is gradually increasing worldwide, and there are socioeconomic inequalities in the risk of developing asthma. OBJECTIVE: To evaluate whether the lifestyle is associated with asthma in adults, as well as whether and to what extent healthy lifestyles may modify socioeconomic status (SES) inequities in asthma. METHODS: This study included a total of 223,951 participants from the UK Biobank. Smoking, physical activity, alcohol consumption, healthy diet patterns, sedentary time, and sleep duration items were used to construct the lifestyle score. Income, education, and occupation were used to assess SES. Cases of adult-onset asthma were identified on the basis of electronic health records. The Cox proportional hazards regression was used to explore the association of socioeconomic inequality and lifestyle factors with asthma. RESULTS: Compared with the most healthy lifestyle category, the hazard ratios (95% CIs) of the moderately healthy lifestyle and least healthy lifestyle categories for asthma were 1.08 (1.01-1.15) and 1.29 (1.20-1.39), respectively. A significant interaction (Pinteraction < .05) was found between lifestyle categories and SES, and the association between them was more pronounced in participants with low SES (hazard ratioleast healthy vs most healthy, 1.58; 95% CI, 1.40-1.80). The joint analysis revealed that the risk of asthma was highest among participants with the lowest SES and the least healthy lifestyles (hazard ratio, 2.02; 95% CI, 1.74-2.33). CONCLUSIONS: Unhealthy lifestyle factors are associated with an increased risk of asthma in adults, and socioeconomically disadvantaged groups are more negatively affected by unhealthy lifestyles. Public health strategies for asthma prevention may need to be tailored according to SES, and social policies to reduce poverty are needed alongside lifestyle interventions in areas of deprivation.


Assuntos
Asma , Estilo de Vida , Classe Social , Humanos , Asma/epidemiologia , Masculino , Feminino , Pessoa de Meia-Idade , Adulto , Estudos de Coortes , Idoso , Reino Unido/epidemiologia , Fatores Socioeconômicos , Idade de Início , Fatores de Risco , Fumar/epidemiologia
3.
Front Nutr ; 10: 1218453, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37457980

RESUMO

Background: Sarcopenia is a common geriatric disease. Many dietary factors may contribute to the development of sarcopenia. Few studies have been conducted on dietary diversity and sarcopenia in Chinese older adults. Among a nationwide sample, the objective of this study is to assess the association between the dietary diversity score (DDS) and the prevalence of possible sarcopenia. We considered the different patterns of dietary diversity in relation to possible sarcopenia. Methods: We conducted this analysis utilizing the cross-sectional data from the 2012, 2014, and 2018 waves of the Chinese longitudinal healthy longevity survey (CLHLS). A standard developed by the Asian Working Group for Sarcopenia 2019 (AWGS2019) was used to assess the possibility of sarcopenia. On the basis of the DDS generated by previous studies, we have constructed four new indicators as follows: total diet, animal-based diet, plant-based diet, and plant-based diet without the consumption of legume products and nuts. We used the generalized estimation equation (GEE) model to evaluate the associations between the DDS of the total diet, animal-based diet, plant-based diet, and plant-based diet without the intake of legume products and nuts and possible sarcopenia. These associations were statistically adjusted for a variety of potential confounders. Sensitivity analysis was performed by excluding some participants who were long-term bedridden, had Alzheimer's disease, or were terminally ill. Results: The analysis included 6,624 participants (mean age 83.4 years at baseline). In our study, we found that participants with a higher DDS of the total diet (OR = 0.62; 95% CI: 0.51-0.77), animal-based diet (OR = 0.62; 95% CI: 0.49-0.79), and plant-based diet (OR = 0.64;95% CI: 0.51-0.80) were at a lower risk of developing sarcopenia. In sensitivity analyses, the associations remained unchanged. Conclusion: Taking a diversified diet, including animal foods, may reduce the risk of developing sarcopenia. According to the findings of this study, adopting a diversified diet might reduce the risk of sarcopenia for older adults.

4.
Front Endocrinol (Lausanne) ; 14: 1123769, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37455916

RESUMO

Misfolded proteins retained in the endoplasmic reticulum cause many human diseases. ER-associated degradation (ERAD) is one of the protein quality and quantity control system located at ER, which is responsible for translocating the misfolded proteins or properly folded but excess proteins out of the ER for proteasomal degradation. Recent studies have revealed that mice with ERAD deficiency in specific cell types exhibit impaired metabolism homeostasis and metabolic diseases. Here, we highlight the ERAD physiological functions in metabolic disorders in a substrate-dependent and cell type-specific manner.


Assuntos
Degradação Associada com o Retículo Endoplasmático , Doenças Metabólicas , Humanos , Animais , Camundongos , Proteínas
5.
Int J Equity Health ; 21(1): 161, 2022 11 15.
Artigo em Inglês | MEDLINE | ID: mdl-36380331

RESUMO

BACKGROUND: Air pollution has been identified as related to the diseases of susceptible population, but the spatial heterogeneity of its economic burden and its determinants are rarely investigated. The issue is of great policy significance, especially after the epidemic of COVID-19, when human are facing the joint crisis of health and environment, and some areas is prone to falling into poverty. METHODS: The geographical detector was adopted to study the spatial distribution characteristics of the incidence of catastrophic health expenditure (ICHE) for older adults in 100 rural areas in China at the prefecture-city level. The health factors, sociological factors, policy factors and environmental factors and their interactions are identified. RESULTS: First, most health service factors had strong explanatory power for ICHE whether it interacts with air pollution. Second, 50 single-factor high-risk areas of ICHE were found in the study, but at the same time, there were 21 areas dominated by multiple factors. CONCLUSION: The different contributions and synergy among the factors constitute the complex mechanism of factors and catastrophic health expenditure. Moreover, during this process, air pollution aggravates the contribution of health service factors toward ICHE. In addition, the leading factors of ICHE are different among regions. At the end, this paper also puts forward some policy suggestions from the perspective of health and environment crisis in the post-COVID-19 world: environmental protection policies should be combined with the prevention of infectious diseases; advanced health investment is the most cost-effective policy for the inverse health sequences of air pollution and infectious diseases such as coronavirus disease 2019 (COVID-19); integrating environmental protection policy into healthy development policy, different regions take targeted measures to cope with the intertwined crisis.


Assuntos
Poluição do Ar , COVID-19 , Humanos , Idoso , COVID-19/epidemiologia , Estresse Financeiro , Poluição do Ar/efeitos adversos , Cidades , Efeitos Psicossociais da Doença , China/epidemiologia
6.
Front Public Health ; 9: 772564, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34869183

RESUMO

Background: There have been very limited prospective studies examining social-cognitive models within stages of behavior change in the exercise domain. Purpose: We examined the utility of the theory of planned behavior (TPB), incorporating self-identity and descriptive norm constructs, to predict exercise behavior across the stages of change, in individuals with type 2 diabetes. Methods: Data were obtained from a longitudinal study. Multi-group structural equation modeling was used to estimate the association between extended TPB constructs and exercise within different stages groups. Results: 647 individuals completed a self-report questionnaire at baseline and at 3 months follow-up. The extended TPB model explained 8-15% variance of exercise behavior and 42-81% variance of exercise intention within three stages groups in the cross-sectional design. The extended TPB model explained 4%-13% variance of exercise behavior and 42-66% variance of exercise intention in the longitudinal design. Intention was significantly related to exercise behavior in the pre-action and action stages. Self-identity, perceived behavioral control and descriptive norms were stronger predictors of intention in different stages. Conclusion: Discontinuity patterns in the extended theory of planned behavior for the different stages groups were found. Intention was a significant predictor of exercise in the pre-action and action stages at 3 months.


Assuntos
Diabetes Mellitus Tipo 2 , China , Estudos Transversais , Humanos , Estudos Longitudinais , Estudos Prospectivos , Modelo Transteórico
7.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao ; 43(4): 513-520, 2021 Aug.
Artigo em Chinês | MEDLINE | ID: mdl-34494520

RESUMO

Objective To understand the current situation and predict the trends in number and composition of prenatal ultrasound screening staff in Beijing. Methods We analyzed the region,age,professional title and other characteristics of prenatal ultrasound screening personnel in Beijing during 2007-2015.We then built an ARIMA model basing on the current situation to predict the number and composition of the staff in 2016-2020. Results The number of prenatal ultrasound screening staff showed an upward trend in 2007-2020 and was predicted to reach 1269 in 2020.During this period,the educational achievement and professional title of the staff showed a downward trend,and the working years became shorter,mainly below 5 years.The proportion of resident doctors remained at 26.6%,and that of the staff receiving further education would reach 43.2% by the end of 2020. Conclusion The prediction under ARIMA model suggests that efforts should be made to strengthen the training of young doctors and provide them opportunities for further study.


Assuntos
Modelos Estatísticos , Diagnóstico Pré-Natal , Pequim , Feminino , Humanos , Gravidez , Ultrassonografia , Ultrassonografia Pré-Natal
8.
Int J Nurs Sci ; 7(Suppl 1): S23-S30, 2020 Sep 10.
Artigo em Inglês | MEDLINE | ID: mdl-32995376

RESUMO

OBJECTIVES: This study was aimed to develop a health belief model scale for exercise among Chinese residents to describe the relationships between health beliefs and exercise for promoting residents to adopt or maintain exercise programs. METHODS: Participants were from two projects, Project 1 with 3833 participants and Project 2 with 7319 participants. A pool of 21 items was developed based on a small-scale qualitative study about health beliefs of exercise and literature. Internal consistency and construct validity of the scale were evaluated with Cronbach's α coefficient, exploratory factor analysis (EFA), confirmatory factor analysis (CFA) and second-order confirmatory factor analysis. RESULTS: A final version of 18 items loaded on six factors which could explain 60.30-% of variance was observed after EFA. The internal consistency of the final version with 18 items performed in Project 1 was acceptable (0.609). The reliability of the six subscales was good with Cronbach's α coefficient of 0.628, 0.713, 0.628, 0.801, 0.676 and 0.838 for perceived benefits, perceived objective barriers, perceived subjective barriers, self-efficacy, perceived severity and cues to action, respectively. CFA and second-order CFA indicated a good fit to data. CONCLUSIONS: The Health Belief Model Scale for Exercise(HBMS-E) is a valid and reliable instrument to assess health beliefs of exercise among residents in China. Understanding the health beliefs of exercise will help health professionals to develop effective interventions for health and evaluate the effectiveness.

9.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao ; 42(3): 347-353, 2020 Jun 30.
Artigo em Chinês | MEDLINE | ID: mdl-32616130

RESUMO

Objective To analyze the efficiency of prenatal ultrasound screening service in Beijing and thus optimize the secondary prevention system for birth defects in Beijing. Methods Data were collected from the prenatal screening work reports of Beijing from 2010-2016.Key variables were extracted after data quality control.Data envelopment analysis was performed to analyze the efficiency and changing trend of ultrasound-based screening service and to compare the service efficiency between urban and suburban areas in Beijing. Results From 2010 to 2016,the technical efficiency of ultrasound screening services showed an increasing trend,and the geometric mean of technical efficiency in suburban areas was higher than that in urban areas.From 2010 to 2016,the total factor productivity of ultrasound screening service increased by 12.3% annually,in which the technical change increased by 12.0% annually;the technical efficiency increased by 0.3%,the pure technical efficiency increased by 13.9% annually,and the scale efficiency decreased by 0.4%.Conclusions The technical efficiency of ultrasound screening service in Beijing increased from 2010 to 2016,and the total factor productivity improved.Technical change and pure technical efficiency change were the main reasons for the improvement.The resource allocation should be further optimized to improve the scale efficiency and enhance the training of prenatal ultrasound screening technicians.


Assuntos
Programas de Rastreamento , Diagnóstico Pré-Natal , Pequim , Feminino , Humanos , Gravidez , Ultrassonografia Pré-Natal
10.
J Affect Disord ; 274: 85-92, 2020 09 01.
Artigo em Inglês | MEDLINE | ID: mdl-32469837

RESUMO

BACKGROUND: The specific impacts of attitudes toward aging on depressive symptoms have not been widely reported in previous studies in China. OBJECTIVES: The aim is to examine the associations between attitudes toward aging, perceived social support, and depressive symptoms among older adults stratified by rural and urban dwelling. METHODS: This study used a cross-sectional data including 7209 participants, among which 64.6% were urban adults and 35.4% were rural adults. Several multiple liner regression models were used to analysis the data. Three social support types were analyzed as moderators of the relationship between the attitudes toward aging and depressive symptoms. RESULTS: Positive attitudes toward aging (ß=-0.139, P<0.001), negative attitudes toward aging (ß=0.284, P<0.001) were significantly associated with lower depressive symptoms among older Chinese adults. Support from family (ß=-0.087, P<0.001), friends (ß=-0.047, P<0.01) and the government (ß=-0.035, P<0.01) were all significantly associated with urban older adults' levels of depressive symptoms. Only family support (ß=-0.109, P<0.001) was associated with lower depressive symptoms among rural older adults'. In addition, family support buffered the effect of negative attitudes toward aging on depressive symptoms for all the older adults, while the moderation effects of support from friends and government only worked for urban elderly. LIMITATIONS: A cross-sectional design is limited to establish causal associations. CONCLUSIONS: Addressing depression among older adults should focus on improving attitudes toward aging and expanding the availability of social support. Moreover, deeper reforms are needed to address inequalities between urban and rural areas in China.


Assuntos
Depressão , Apoio Social , Idoso , Envelhecimento , Atitude , China/epidemiologia , Estudos Transversais , Depressão/epidemiologia , Humanos , Pessoa de Meia-Idade , População Rural
11.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao ; 39(4): 525-533, 2017 Aug 20.
Artigo em Inglês | MEDLINE | ID: mdl-28877831

RESUMO

Objective To construct composite indicators of maternal and child's basic health services using different weights from the prospective of continuum of care and to compare them based on data from the National Health Services Survey 2008 and 2013 in Jilin Province. Methods The study selected indicators based on the countdown and the Lives Saved Tool(LiST),considering the data availability from the 2008 and 2013 National Health Surveys in Jilin.Equal weights,equal weights for different areas,epidemiology weights,and principal component weights were used to construct different composite indicators.Cronbach's alpha reliability coefficient was used to test the internal consistency.Analysis of variance of randomized block design was used to test the differences.The Spearman's correlation coefficient was calculated to compare the rank correlation.The maternal mortality,children under 5 years old mortality rate,and children under 5 years old stunting incidence were used as the outcome indicators to test the validity using correlation analysis. Results Finally 13 indicators were selected,with the Cronbach's alpha reliability coefficient value exceeding 0.7,which means acceptable internal consistency of these indicators.Analysis of variance showed that the scores were not significantly the same(F=8.14,P<0.01).The rank correlations among equal weights,principal component weights,and equal weights for different areas composite indicators were quite strong,and the Spearman's correlation coefficient between either two were all above 0.9,while the epidemiology weights composite indicator got smaller Spearman's correlation coefficient with equal weights,principal component weights,and equal weights for different areas composite indicators(0.697,0.671,and 0.818,respectively).The composite indicator using epidemiology weights showed significant negative correlation with children under 5 years old mortality rate and children under 5 years old stunting incidence(R2=0.168,P<0.05;R2=0.398,P<0.01,respectively).The composite indicators using equal weights,equal weights for different areas and principal component weights only showed significant negative correlation with children under 5 years old stunting incidence(R2=0.238,R2=0.304,R2=0.232,P<0.01 for all,respectively).Conclusion The composite indicator using epidemiology objective weights has some predictive value for maternal and child health outcomes.


Assuntos
Serviços de Saúde da Criança/normas , Serviços de Saúde Materna/normas , Programas Nacionais de Saúde , Indicadores de Qualidade em Assistência à Saúde , Mortalidade da Criança , Pré-Escolar , China/epidemiologia , Feminino , Transtornos do Crescimento/epidemiologia , Humanos , Mortalidade Materna , Qualidade da Assistência à Saúde/normas , Reprodutibilidade dos Testes , Inquéritos e Questionários
12.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao ; 39(2): 247-253, 2017 04 20.
Artigo em Inglês | MEDLINE | ID: mdl-28483025

RESUMO

Objective To examine the two-week morbidity rates and the associated factors among the residents of Jilin province and to learn the health services needs among residents before and after new health care reform and provide basis for the establishment of health planning. Methods We used the data from the National Health Services Survey of Jilin from 2008 to 2013,with a total sample size of 29 495. Descriptive analyses were performed to analyze two-week morbidity rates,and Logistic regression was employed to explore the associated factors. Results From 2008 to 2013,the two-week morbidity rate increased from 9.2% to 25.7% (P<0.001). In 2013 and 2008,the two-week morbidities of onset had significantly different compositions (χ2=240.86,P<0.001). Chronic conditions continuing to two weeks accounted for 80.4% in the onset time of two weeks in 2013. Hypertension,diabetes,and other chronic diseases had become the leading disorders. The influential factors of the two-week morbidity in 2008 were residency (OR=0.97,95% CI=0.64-0.93),age (OR=2.29,95% CI=1.46-3.60),marital status (OR=2.05,95% CI=1.28-3.27),and chronic diseases (OR=15.02,95% CI=12.93-17.43).The influential factors of the two-week morbidity in 2013 were age (OR=4.79,95% CI=3.01-7.63),chronic diseases (OR=60.14,95% CI=53.03-68.21),and medical insurance coverage (OR=1.33,95% CI=1.03-1.74). Conclusion The needs for health care services have dramatically increased after new health care reform among residents of Jilin province. Chronic diseases have become the major health concerns.


Assuntos
Doença Crônica/epidemiologia , Reforma dos Serviços de Saúde , Morbidade , Autorrelato , China/epidemiologia , Planejamento em Saúde , Necessidades e Demandas de Serviços de Saúde , Humanos , Modelos Logísticos , Inquéritos e Questionários
13.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao ; 39(2): 254-260, 2017 Apr 20.
Artigo em Inglês | MEDLINE | ID: mdl-28483026

RESUMO

Objective To analyze the influencing factors of stunting in children under 5 years old in Jilin province in 2013,with an attempt to further improve the nutrition status among children. Methods Data on stunting in children under 5 years old in Jilin province were extracted from the National Health Services Survey 2013 in Jilin province. The influencing factors of stunting were analyzed by using univariate analysis and Logistic regression analysis.. Results The stunting prevalence in children under 5 years old was 23.8% in 2013. Univariate analysis showed that urban residence (OR=0.38,95% CI=0.25-0.57),high income (OR=0.40,95% CI=0.24-0.66),mother's education level (higher than primary school) (OR=0.50,95% CI=0.32-0.81),safe water coverage (OR=0.41,95% CI=0.22-0.75),and clean toilet coverage (OR=0.36,95% CI=0.24-0.53) are protective factors of stunting. After adjusting other factors,urban residence (OR=0.54,95% CI=0.31-0.94),safe water coverage (OR=0.28,95% CI=0.13-0.60),and clean toilet coverage (OR=0.40,95% CI=0.24-0.67) still showed protective effects. Conclusion The urban-rural disparity and the availability of safe water and clean toilet are the major factors of stunting among children under 5 years old in Jilin province. The major public health service program should be fully implemented to improve the nutrition status among children.


Assuntos
Transtornos do Crescimento/epidemiologia , Estado Nutricional , Pré-Escolar , China/epidemiologia , Disparidades nos Níveis de Saúde , Inquéritos Epidemiológicos , Humanos , Higiene , Lactente , Prevalência , Fatores de Risco , População Rural , População Urbana , Qualidade da Água
14.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao ; 39(2): 261-265, 2017 Apr 20.
Artigo em Inglês | MEDLINE | ID: mdl-28483027

RESUMO

Objective To understand the health-related quality of life (HRQoL) and its influencing factors in Jilin province and compare two life quality measurement methods. Methods The data of 13 700 people aged above 15 years in Jilin province were extracted from the National Health Services Survey 2013. Self-rated health scores and EuroQol 5-dimension utility values were used to evaluate the HRQoL. Multivariable linear regression model was used to analyze the influencing factors. Results The self-rated health score was 81.26±15.73 in Jilin province,while utility values of health status were 0.959±0.124. The influencing factors of HRQoL included age,residency,education,income,type of health insurance,having non-communicable chronic disease and having disease in last two weeks. The age under 45,income,having non-communicable chronic disease,and having disease in last two weeks had stronger effect on self-rated health,whereas residency and type of health insurance had more effect on utility values of health status. Conclusion People in Jilin province have good quality of life. Both methods have their advantages and weakness. It is important to choose the right evaluation method depended on the objective of a specific study.


Assuntos
Nível de Saúde , Qualidade de Vida , Inquéritos e Questionários , China , Humanos
15.
Electrophoresis ; 37(15-16): 2260-72, 2016 08.
Artigo em Inglês | MEDLINE | ID: mdl-27184937

RESUMO

The 19 X-STRs multiplex system is a PCR-based amplification kit that facilitates simultaneous amplification of 19 X-chromosomal STR loci (i.e. DXS7423, DXS10148, DXS10159, DXS6809, DXS7424, DXS8378, DXS10164, DXS10162, DXS7132, DXS10079, DXS6789, DXS101, DXS10103,DXS10101, HPTRB, DXS10075, DXS10074, DXS10135, and DXS10134). Eleven loci were extensively used in an Investigator Qiagen Argus X-12 (DXS7423, DXS10148, DXS8378, DXS10162, DXS7132, DXS10079, DXS10103, DXS10101, HPTRB, DXS10074, and DXS10135). In this research, the multiplex system was tested for detection sensitivity, DNA mixtures, inhibitor tolerance and species specificity; SWGDAM Validation Guidelines - Approved December 2012 were followed for the human fluorescent STR multiplex PCR reagent. Samples from 181 unrelated Zhejiang Han individuals (121 males and 60 females) were typed using this multiplex system. The results show that this 19X-STRs multiplex system is a robust and reliable amplification means to facilitate forensic and human identification testing.


Assuntos
Cromossomos Humanos X , Impressões Digitais de DNA/métodos , Genética Populacional/métodos , Reação em Cadeia da Polimerase Multiplex/métodos , Animais , China , Feminino , Testes Genéticos , Humanos , Masculino , Sensibilidade e Especificidade , Especificidade da Espécie
16.
Beijing Da Xue Xue Bao Yi Xue Ban ; 46(2): 220-5, 2014 Apr 18.
Artigo em Chinês | MEDLINE | ID: mdl-24743810

RESUMO

OBJECTIVE: To investigate the outpatient provider preference and its influencing factors among residents older than 45 years in China's urban areas. METHODS: The data of China Health and Retirement Longitudinal Survey (CHARLS) taking place in the year 2011 were analyzed with the method of multinominal logistic regression. RESULTS: In the last month, the rates of respondents with hypertension or/and diabetes who were reported being ill and seeking treatment were higher than that of those without such diseases. 51.73% of the hypertensive and 64.81% of the diabetic preferred hospitals to community health service (CHS) and private clinics. Regression results showed that people with Urban Employee Basic Medical Insurance (UEBMI), higher education level, higher capacity to pay and diabetes tended to choose hospitals rather than CHS. CONCLUSION: Urban people with non-communicable diseases (NCDs) preferred to use hospitals rather than the CHS, which reflected CHS's low performance in NCDs management. UEBMI failed to channel off the insured people to CHS. CHS needs to strengthen its ability to manage NCDs, and UEBMI should implement measures to attract patients' flow to CHS.


Assuntos
Serviços de Saúde Comunitária , Hospitais , Preferência do Paciente , População Urbana , Idoso , China , Diabetes Mellitus , Inquéritos Epidemiológicos , Humanos , Hipertensão , Modelos Logísticos , Estudos Longitudinais , Pacientes Ambulatoriais
17.
Beijing Da Xue Xue Bao Yi Xue Ban ; 43(3): 391-6, 2011 Jun 18.
Artigo em Inglês | MEDLINE | ID: mdl-21681270

RESUMO

OBJECTIVE: China was categorized as one of the 68 "countdown" countries to achieve the United Nations Millennium Development Goals (MDG) 5. This paper aimed to analyze the situation of maternal survival, and coverage of proven cost effective interventions in China, where specific attention was paid to disparities. METHODS: National maternal and child mortality surveillance data were used to estimate maternal mortality ratio (MMR). Coverage for proven interventions was analyzed based on National Health Services Survey, where experts' consultations were made for complementation. RESULTS: There had been a significant reduction of MMR in China, however great disparities existed, with rural II to IV areas experiencing 2 to 5 times higher maternal mortality risks than urban areas and accounting for over 70% maternal mortality burdens. Postpartum hemorrhage, pregnancy associated hypertension, embolism and sepsis were the leading causes, and over 75% of the maternal mortality was caused by preventable or curable causes. Maternal health services utilization decreased in accordance with region's development level. Socioeconomic factors like financial difficulties were the main obstacles hindering access of care. Even those who made deliveries in hospitals faced different probabilities in receiving qualified care according to their socioeconomic standings. CONCLUSION: China is on track to achieve MDG 5, however great disparities exist. It is necessary to specifically target rural types II to IV areas. Major causes of maternal mortality which can be prevented or averted through the provision of essential obstetrical care. Yet as compared with maternity health needs, insufficient coverage of maternal and child health (MCH) care services and poor service quality are the leading predisposing factors contributing to maternal mortality in China.


Assuntos
Mortalidade Materna , Hemorragia Pós-Parto/mortalidade , Pré-Eclâmpsia/mortalidade , Infecção Puerperal/mortalidade , Adulto , China/epidemiologia , Feminino , Humanos , Cooperação Internacional , Serviços de Saúde Materna , Complicações do Trabalho de Parto/mortalidade , Gravidez , Complicações na Gravidez/mortalidade , Saúde da População Rural , Nações Unidas
18.
Beijing Da Xue Xue Bao Yi Xue Ban ; 42(3): 252-7, 2010 Jun 18.
Artigo em Chinês | MEDLINE | ID: mdl-20559396

RESUMO

OBJECTIVE: To investigate the impact of social determinants of health on the inequality of child health and health care utilization. METHODS: Information of 1 118 children aged 0 to 16 is extracted from the Chinese Family Panel Studies (CFPS) year 2008 cross sectional survey data for the analysis. Age standardized concentration curves and concentration indices are employed to assess the inequalities for incidence of low birth weight, self reported good health, adequate timing of breast feeding, health insurance coverage and incidence of catastrophic health expenditures for these children. Concentration indices are decomposed to four levels of social determinants of health(community, family, mother and individual level) to understand their contributions to health inequality respectively. RESULTS: There are health inequalities existing in the investigated children, among which social factors at mother and family level have the largest contribution. CONCLUSION: To respond to the call by the WHO to achieve health equity through action on the social determinants of health in a generation, the inequalities of health and health care utilization amongst Chinese children should be put on the policy agenda, and social policies should intervene from multiple social dimensions, especially from family and mother levels.


Assuntos
Proteção da Criança , Fatores Socioeconômicos , Adolescente , Criança , Pré-Escolar , China , Feminino , Humanos , Lactente , Masculino
19.
Adv Health Sci Educ Theory Pract ; 14(1): 91-102, 2009 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-18274879

RESUMO

To explore the need for faculty development among Chinese medical educators. Leaders at each medical school in China were asked to complete a 123-item survey to identify interest in various topics and barriers and perceived benefits of participating in faculty development programs. Interest levels were high for all topics. Experience with Hospital Management and Research positively correlated with interest in learning more (p < 0.001). Ninety-two percent believe that international experiences are very or extremely important to medical educators' career advancement. Chinese medical education faculty members have a strong interest in faculty development programs.


Assuntos
Educação Médica Continuada/métodos , Educação Médica/métodos , Docentes de Medicina , Adulto , Idoso , China , Feminino , Humanos , Cooperação Internacional , Masculino , Pessoa de Meia-Idade , Meio-Oeste dos Estados Unidos , Avaliação das Necessidades , Desenvolvimento de Pessoal/métodos
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