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Front Endocrinol (Lausanne) ; 13: 959487, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36060931

RESUMO

Non-coding RNAs are classified as small non-coding RNAs, long non-coding RNAs and circular RNAs, which are involved in a variety of biological processes, including cell differentiation, proliferation, apoptosis and pathological conditions of various diseases. Many studies have shown that non-coding RNAs are related to spermatogenesis, maturation, apoptosis, function, etc. In addition, the expression of non-coding RNAs in testicular tissue and semen of patients with non-obstructive azoospermia was different. However, the role of non-coding RNAs in the pathogenesis of non-obstructive azoospermia has not been fully elucidated, and the role of non-coding RNAs in non-obstructive azoospermia is rarely reviewed. Here we summarize the research progress of non-coding RNAs in the pathogenesis of non-obstructive azoospermia.


Assuntos
Azoospermia , RNA Longo não Codificante , Azoospermia/genética , Azoospermia/metabolismo , Azoospermia/patologia , Regulação da Expressão Gênica , Humanos , Masculino , RNA Circular , RNA Longo não Codificante/genética , Espermatogênese/genética
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