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1.
Sci Rep ; 7(1): 16463, 2017 11 28.
Artigo em Inglês | MEDLINE | ID: mdl-29184108

RESUMO

A new type of proton acceleration stemming from large-scale gradients, low-density targets, irradiated by an intense near-infrared laser is observed. The produced protons are characterized by high-energies (with a broad spectrum), are emitted in a very directional manner, and the process is associated to relaxed laser (no need for high-contrast) and target (no need for ultra-thin or expensive targets) constraints. As such, this process appears quite effective compared to the standard and commonly used Target Normal Sheath Acceleration technique (TNSA), or more exploratory mechanisms like Radiation Pressure Acceleration (RPA). The data are underpinned by 3D numerical simulations which suggest that in these conditions a Low Density Collisionless Shock Acceleration (LDCSA) mechanism is at play, which combines an initial Collisionless Shock Acceleration (CSA) to a boost procured by a TNSA-like sheath field in the downward density ramp of the target, leading to an overall broad spectrum. Experiments performed at a laser intensity of 1020 W/cm2 show that LDCSA can accelerate, from ~1% critical density, mm-scale targets, up to 5 × 109 protons/MeV/sr/J with energies up to 45(±5) MeV in a collimated (~6° half-angle) manner.

2.
Phys Med ; 42: 313-318, 2017 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-28676259

RESUMO

One of the big challenges of the emerging MRI-guided radiotherapy is the prediction of an external magnetic field effect on the deposited dose induced by a beam of charged particles. In this paper, we present the results of the implementation of the Lorentz force in the deterministic M1 model. The validation of our code is performed by comparisons with the Monte-Carlo code FLUKA. The relevant examples show a significant modification of the shape of dose deposition volume induced by the external magnetic field in presence of heterogeneities. A gamma-index analysis 3%/3mm shows a good agreement of our model with FLUKA simulations.


Assuntos
Algoritmos , Campos Magnéticos , Modelos Teóricos , Radioterapia , Simulação por Computador , Elétrons , Humanos , Imageamento por Ressonância Magnética , Método de Monte Carlo , Fótons , Dosagem Radioterapêutica , Planejamento da Radioterapia Assistida por Computador , Água
3.
Phys Rev Lett ; 118(20): 205001, 2017 May 19.
Artigo em Inglês | MEDLINE | ID: mdl-28581770

RESUMO

Collimated transport of ultrahigh intensity electron current was observed in cold and in laser-shocked vitreous carbon, in agreement with simulation predictions. The fast electron beams were created by coupling high-intensity and high-contrast laser pulses onto copper-coated cones drilled into the carbon samples. The guiding mechanism-observed only for times before the shock breakout at the inner cone tip-is due to self-generated resistive magnetic fields of ∼0.5-1 kT arising from the intense currents of fast electrons in vitreous carbon, by virtue of its specific high resistivity over the range of explored background temperatures. The spatial distribution of the electron beams, injected through the samples at different stages of compression, was characterized by side-on imaging of hard x-ray fluorescence.

4.
Phys Med ; 31(8): 912-921, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26701765

RESUMO

A new deterministic method for calculating the dose distribution in the electron radiotherapy field is presented. The aim of this work was to validate our model by comparing it with the Monte Carlo simulation toolkit, GEANT4. A comparison of the longitudinal and transverse dose deposition profiles and electron distributions in homogeneous water phantoms showed a good accuracy of our model for electron transport, while reducing the calculation time by a factor of 50. Although the Bremsstrahlung effect is not yet implemented in our model, we propose here a method that solves the Boltzmann kinetic equation and provides a viable and efficient alternative to the expensive Monte Carlo modeling.


Assuntos
Elétrons/uso terapêutico , Modelos Teóricos , Método de Monte Carlo , Imagens de Fantasmas , Dosagem Radioterapêutica , Planejamento da Radioterapia Assistida por Computador , Radioterapia Assistida por Computador , Água
5.
Rev Sci Instrum ; 86(4): 043502, 2015 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-25933857

RESUMO

Ultra-intense lasers can nowadays routinely accelerate kiloampere ion beams. These unique sources of particle beams could impact many societal (e.g., proton-therapy or fuel recycling) and fundamental (e.g., neutron probing) domains. However, this requires overcoming the beam angular divergence at the source. This has been attempted, either with large-scale conventional setups or with compact plasma techniques that however have the restriction of short (<1 mm) focusing distances or a chromatic behavior. Here, we show that exploiting laser-triggered, long-lasting (>50 ps), thermoelectric multi-megagauss surface magnetic (B)-fields, compact capturing, and focusing of a diverging laser-driven multi-MeV ion beam can be achieved over a wide range of ion energies in the limit of a 5° acceptance angle.

6.
Artigo em Inglês | MEDLINE | ID: mdl-24730956

RESUMO

Shock ignition concept is a promising approach to inertial confinement fusion that may allow obtaining high fusion energy gains with the existing laser technology. However, the spike driving laser intensities in the range of 1-10 PW/cm2 produces the energetic electrons that may have a significant effect on the target performance. The hybrid numerical simulations including a radiation hydrodynamic code coupled to a rapid Fokker-Planck module are used to asses the role of hot electrons in the shock generation and the target preheat in the time scale of 100 ps and spatial scale of 100 µm. It is shown that depending on the electron energy distribution and the target density profile the hot electrons can either increase the shock amplitude or preheat the imploding shell. In particular, the exponential electron energy spectrum corresponding to the temperature of 30 keV in the present HiPER target design preheats the deuterium-tritium shell and jeopardizes its compression. Ways of improving the target performance are suggested.

7.
Artigo em Inglês | MEDLINE | ID: mdl-25615206

RESUMO

Controlling the divergence of laser-driven fast electrons is compulsory to meet the ignition requirements in the fast ignition inertial fusion scheme. It was shown recently that using two consecutive laser pulses one can improve the electron-beam collimation. In this paper we propose an extension of this method by using a sequence of several laser pulses with a gradually increasing intensity. Profiling the laser-pulse intensity opens a possibility to transfer to the electron beam a larger energy while keeping its divergence under control. We present numerical simulations performed with a radiation hydrodynamic code coupled to a reduced kinetic module. Simulation with a sequence of three laser pulses shows that the proposed method allows one to improve the efficiency of the double pulse scheme at least by a factor of 2. This promises to provide an efficient energy transport in a dense matter by a collimated beam of fast electrons, which is relevant for many applications such as ion-beam sources and could present also an interest for fast ignition inertial fusion.

8.
Phys Rev Lett ; 109(1): 015001, 2012 Jul 06.
Artigo em Inglês | MEDLINE | ID: mdl-23031109

RESUMO

This Letter describes the first experimental demonstration of the guiding of a relativistic electron beam in a solid target using two colinear, relativistically intense, picosecond laser pulses. The first pulse creates a magnetic field that guides the higher-current, fast-electron beam generated by the second pulse. The effects of intensity ratio, delay, total energy, and intrinsic prepulse are examined. Thermal and Kα imaging show reduced emission size, increased peak emission, and increased total emission at delays of 4-6 ps, an intensity ratio of 10∶1 (second:first) and a total energy of 186 J. In comparison to a single, high-contrast shot, the inferred fast-electron divergence is reduced by 2.7 times, while the fast-electron current density is increased by a factor of 1.8. The enhancements are reproduced with modeling and are shown to be due to the self-generation of magnetic fields. Such a scheme could be of considerable benefit to fast-ignition inertial fusion.

9.
Phys Rev Lett ; 109(25): 255004, 2012 Dec 21.
Artigo em Inglês | MEDLINE | ID: mdl-23368476

RESUMO

An intense beam of high energy electrons may create extremely high pressures in solid density materials. An analytical model of ablation pressure formation and shock wave propagation driven by an energetic electron beam is developed and confirmed with numerical simulations. In application to the shock-ignition approach in inertial confinement fusion, the energy transfer by fast electrons may be a dominant mechanism of creation of the igniting shock wave. An electron beam with an energy of 30 keV and energy flux 2-5 PW/cm(2) can create a pressure amplitude more than 300 Mbar for a duration of 200-300 ps in a precompressed solid material.

10.
Phys Rev E Stat Nonlin Soft Matter Phys ; 84(1 Pt 2): 016402, 2011 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-21867317

RESUMO

In the fast-ignition scheme, relativistic electrons transport energy from the laser deposition zone to the dense part of the target where the fusion reactions can be ignited. The magnetic fields and electron collisions play an important role in the collimation or defocusing of this electron beam. Detailed description of these effects requires large-scale kinetic calculations and is limited to short time intervals. In this paper, a reduced kinetic model of fast electron transport coupled to the radiation hydrodynamic code is presented. It opens the possibility to carry on hybrid simulations in a time scale of tens of picoseconds or more. It is shown with this code that plasma-generated magnetic fields induced by noncollinear temperature and density gradients may strongly modify electron transport in a time scale of a few picoseconds. These fields tend to defocus the electron beam, reducing the coupling efficiency to the target. This effect, that was not seen before in shorter time simulations, has to be accounted for in any ignition design using electrons as a driver.

11.
Phys Rev Lett ; 98(9): 095002, 2007 Mar 02.
Artigo em Inglês | MEDLINE | ID: mdl-17359162

RESUMO

Correct modeling of the electron-energy transport is essential for inertial confinement fusion target design. Various transport models have been proposed in order to extend the validity of a hydrodynamical description into weakly collisional regimes, taking into account the nonlocality of the electron transport combined with the effects of self-generated magnetic fields. We have carried out new experiments designed to be highly sensitive to the modeling of the heat flow on the Ligne d'Intégration Laser facility, the prototype of the Laser Megajoule. We show that two-dimensional hydrodynamic simulations correctly reproduce the experimental results only if they include both the nonlocal transport and magnetic fields.

12.
Ann Fr Anesth Reanim ; 26(3): 245-8, 2007 Mar.
Artigo em Francês | MEDLINE | ID: mdl-17258884

RESUMO

Functionality of the nerve stimulator and integrity of the electrical circuit should be verified and confirmed before performing peripheral nerve blockade. The clinical cases reported here demonstrate that electrical disconnection or malfunction during nerve localization can unpredictably occur and a checklist is described to prevent the unknown electrical circuit failure.


Assuntos
Bloqueio Nervoso/efeitos adversos , Bloqueio Nervoso/métodos , Estimulação Elétrica Nervosa Transcutânea/instrumentação , Adulto , Falha de Equipamento , Feminino , Humanos , Estimulação Elétrica Nervosa Transcutânea/efeitos adversos
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