RESUMO
Tineabarbae is a rare form of dermatophytosis that affects hair follicles of the beard and moustache. Dermoscopy could prove useful to identify parasitism of hair of the beard, just as it has proven useful in the diagnosis of Tineacapitis. We present the first fully documented case series of T. barbae with clinical, dermoscopic and mycological features.
Assuntos
Dermoscopia/métodos , Dermatoses Faciais/diagnóstico , Microscopia/métodos , Tinha/diagnóstico , Adulto , Dermoscopia/normas , Diagnóstico Diferencial , Face , Dermatoses Faciais/microbiologia , Cabelo/microbiologia , Humanos , Masculino , Microscopia/normas , Pessoa de Meia-Idade , Couro Cabeludo/microbiologia , Tinha/microbiologiaAssuntos
Poroceratose/diagnóstico , Poroceratose/patologia , Nádegas , Humanos , Masculino , Pessoa de Meia-IdadeAssuntos
Fármacos Dermatológicos/administração & dosagem , Fibromatose Agressiva/tratamento farmacológico , Metotrexato/administração & dosagem , Psoríase/complicações , Adolescente , Feminino , Fibromatose Agressiva/complicações , Humanos , Psoríase/tratamento farmacológico , Indução de Remissão/métodosAssuntos
Eritrodermia Ictiosiforme Congênita/genética , Erros Inatos do Metabolismo Lipídico/genética , Doenças Musculares/genética , Adulto , Feminino , Humanos , Eritrodermia Ictiosiforme Congênita/diagnóstico , Erros Inatos do Metabolismo Lipídico/diagnóstico , Masculino , Doenças Musculares/diagnóstico , IrmãosRESUMO
INTRODUCTION: Clinical expression of psoriasis is in part dependent on external factors, such as drugs, microorganisms or stress. However convincing evidence of the role of Malassezia species in the pathogenesis of the psoriasis is still lacking. PATIENTS AND METHODS: Samples taken from scalp skin of 40 psoriatic patients and the same number of healthy individuals were observed under direct microsocopic examination and cultured on modified Dixon agar. RESULTS: Direct microscopy examination of psoriatic scalp scales was positive in 30 (75%) patients; while it was positive in only 12 (30%) healthy subjects (P=0.003). Half of the cultures from healthy subjects showed no growth of colonies, but only 8 (15%) of psoriatic patients were negative. When an exacerbation has occurred in the previous weeks, pseudohyphaes were observed in 12 (40%) patients, Malassezia globosa was isolated in 18 (45%) patients and Malassezia restricta was isolated in 12 (30%) patients. In the group of patients having stable lesion, without any exacerbation in the previous weeks, no pseudohypahes were observed, M. globosa was not isolated, M. restricta was isolated in 4 (10%), and cultures were negative in 6 of them (15%). CONCLUSIONS: Malassezia species form an integral part of normal cutaneous microflora in humans, however we found that during the episodes of exacerbation of the disease the presence of these yeasts, and particularly M. globosa, was increased.
Assuntos
Dermatomicoses/complicações , Malassezia/fisiologia , Psoríase/microbiologia , Couro Cabeludo/microbiologia , Adolescente , Adulto , Idoso , Dermatomicoses/epidemiologia , Dermatomicoses/microbiologia , Progressão da Doença , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Psoríase/epidemiologia , Psoríase/patologia , Couro Cabeludo/patologia , Adulto JovemRESUMO
Histoplasmosis is a fungal infection caused by a dimorphic fungus, Histoplasma capsulatum. Most infections occur after inhalation of fungal spores. A wide variety of clinical manifestations can occur depending on the host response and the extent of inoculation. We report a case of probable cutaneous histoplasmosis after trauma in a 26-year-old man from Paraguay who was also infected with the human immunodeficiency virus. Diagnosis was based on histological and mycological examination. No systemic involvement was found.
Assuntos
Hiperpigmentação/patologia , Prurigo/patologia , Adulto , Exantema/etiologia , Feminino , Humanos , Hiperpigmentação/complicações , Pescoço , Prurigo/complicações , Recidiva , TóraxAssuntos
Acantólise/induzido quimicamente , Aminoquinolinas/efeitos adversos , Antineoplásicos/efeitos adversos , Toxidermias/etiologia , Pitiríase Rubra Pilar/induzido quimicamente , Acantólise/complicações , Aminoquinolinas/administração & dosagem , Antineoplásicos/administração & dosagem , Toxidermias/complicações , Humanos , Imiquimode , Masculino , Pessoa de Meia-Idade , Preparações Farmacêuticas , Pitiríase Rubra Pilar/complicaçõesRESUMO
INTRODUCTION: Knowledge of the dangers of sun exposure does not always lead to changes in behavior. Failure to make behavioral adjustments is of particular concern in high-risk patients. OBJECTIVES: a) To assess the impact of melanoma diagnosis on knowledge, attitudes, and behaviors relating to sun protection, and b) to identify factors that could influence sun protection behaviors. METHODS: A coded, anonymous questionnaire was given to 195 patients with a recent diagnosis of melanoma. Data were collected on clinical and demographic variables and on knowledge, attitudes, and behaviors relating to sun protection before and after diagnosis. The questionnaire also addressed patients' sense of distress and guilt following diagnosis. RESULTS: Sun protection behaviors improved following diagnosis in 66% of patients. Although 98% of patients reported having received advice on sun protection following diagnosis, 15% continued to take inadequate sun protection measures. The probability of behavioral improvement following diagnosis was 4 times greater in women than in men. The subgroup of patients whose behavior improved had worse behaviors prior to diagnosis than did those who showed no improvement. Patients who expressed distress and feelings of guilt following diagnosis were more likely to improve their sun protection behavior. Age, tumor site, intensiveness of treatment, and belief that a suntan is healthy had no significant influence on behavioral change. CONCLUSIONS: Melanoma diagnosis is associated with increased knowledge of sun protection measures and improvement in behaviors. Nevertheless, patients continue to use inadequate sun protection measures. Identification of barriers to optimal sun protection behavior may be instrumental in designing targeted educational campaigns.
Assuntos
Conhecimentos, Atitudes e Prática em Saúde , Melanoma/prevenção & controle , Neoplasias Cutâneas/prevenção & controle , Protetores Solares/uso terapêutico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Inquéritos e QuestionáriosRESUMO
BACKGROUND: Topical antifungal treatment is indicated in tinea of glabrous skin, except in cases of extensive, multiple or recurrent lesions, or immunocompromised patients. However, in daily practice there are cases resistant to topical treatment despite these indications. Parasitism of the hair could be the cause behind the majority of isolated lesions of ringworm of hairless skin with a poor outcome with topical antifungal treatment. OBJECTIVES: To present a prospective observational study of 13 cases of tinea of glabrous skin with topical antifungal resistance during the period 2007-2009. METHODS: Cases were analysed from a clinical, mycological and therapeutic standpoint. RESULTS: The mean age was 7 years. Eight (62%) patients reported prior contact with an animal and 10 (77%) patients had received topical corticosteroids before visiting the dermatologist. Excoriation was observed in eight (62%) patients, and follicular micropustules were seen in 11 (85%). In all patients, some short thin hairs fell easily on to the slide during the skin scraping. In all patients all the few vellus hairs identified in direct examination were affected. All identified species were zoophilic or geophilic. All cases resolved after oral antifungal treatment. CONCLUSIONS: In tinea of glabrous skin with low response to topical antifungal treatment we must rule out tinea of the vellus hair. Infection by nonanthropophilic dermatophytes, previous corticosteroid therapy and excoriation might be predisposing factors. Parasitism of the vellus hair, observed by direct microscopy, should be another criterion for establishing systemic treatment from the onset, as is the case in tinea capitis.
Assuntos
Antifúngicos/uso terapêutico , Cabelo/microbiologia , Tinha/tratamento farmacológico , Administração Oral , Adulto , Criança , Pré-Escolar , Resistência a Medicamentos , Feminino , Humanos , Masculino , Estudos Prospectivos , Tinha/patologiaAssuntos
Carcinoma Basocelular/complicações , Melanoma/complicações , Neoplasias Primárias Múltiplas/complicações , Doença de Parkinson/complicações , Neoplasias Cutâneas/complicações , Adulto , Antiparkinsonianos/efeitos adversos , Antiparkinsonianos/uso terapêutico , Carcinoma Basocelular/cirurgia , Suscetibilidade a Doenças , Dopamina/biossíntese , Agonistas de Dopamina/efeitos adversos , Agonistas de Dopamina/uso terapêutico , Humanos , Levodopa/efeitos adversos , Levodopa/uso terapêutico , Masculino , Melaninas/biossíntese , Melanoma/cirurgia , Doença de Parkinson/tratamento farmacológico , Neoplasias Cutâneas/cirurgiaAssuntos
Dermatomicoses/diagnóstico , Exophiala/isolamento & purificação , Dermatoses da Mão/diagnóstico , Úlcera Cutânea/microbiologia , Polegar/microbiologia , Idoso de 80 Anos ou mais , Dermatomicoses/microbiologia , Exophiala/crescimento & desenvolvimento , Dermatoses da Mão/microbiologia , Humanos , Masculino , Onicomicose/microbiologiaRESUMO
Although pityriasis versicolor is the only human disease for which Malassezia yeasts have been fully established as pathogens, it is still not clear which species are implicated. Most studies carried out in recent years support our hypothesis - proposed in 1999 - that Malassezia globosa is the predominant species in pityriasis versicolor lesions, at least in temperate climates. Confirmation of this hypothesis could help us understand the conditions, as yet unclear, that induce transformation of this yeast from the saprophytic form present in healthy skin to the parasitic form, characterized by the formation of pseudomycelium, and could also guide therapy. In addition, isolation of another species, Malassezia furfur, which seems to be predominant in the tropics, raises the possibility of a second etiologic agent confined to certain areas, as occurs with some other human mycoses.