Investigation of skincare habits and possible rosacea triggers of patients with rosacea: A prospective case-control study.

OBJECTIVE: Skincare is a part of rosacea treatment; patients benefit from complementary dermo-cosmetic care as well as medical treatments. Some skincare habits are known to trigger and exacerbate rosacea, but there are very few epidemiological studies on this matter. METHODS: A total of 200 people, including 100 patients with rosacea and 100 controls, were included in the study. We questioned the methods used by the participants in daily facial cleansing. Sun and heat exposure, makeup habits, the history of the use of topical steroids, and outdoor working status were noted. A dermoscopic examination, a non-invasive and valuable method to evaluate the presence and severity of Demodex, was performed. RESULTS: We evaluated 30% of our rosacea patients as erythematotelangiectatic rosacea, 13% as papulopustular rosacea, and 57% of our patients had mixed type, which could not be distinguished from one of these subtypes. In the case group, the proportion of people who used daily facial cleansers and daily soaps was lower than in the control group, while the proportion of those who cleaned their face with only water and those who used facial cleansers less frequently was higher (p<0.001). In the case group, while the rate of daily make-up and use of make-up products was lower (p=0.001, p<0.001, respectively), the rate of not wearing make-up was higher (p=0.001). The history of hot bath use was higher in the case group than in the control group (p=0.011). We found a significant relationship between the severity of plaque and dry appearance and the increase in Demodex density (p=0.007, p<0.001, respectively). CONCLUSION: We recommend that patients with rosacea clean their faces daily with soap or facial cleansers and not take a bath with very hot water. Patients should be evaluated for increased Demodex mites, especially if skin dryness is accompanied.

Investigation of the Chemical Content and User Comments on Facial Cleansing Products.

BACKGROUND: The goal of skin cleansing is to reduce sebum and exogenous pollutants and control the skin microbiome. Surfactants in cleansers dissolve hydrophobic substances in an aqueous phase and allow them to move away from the skin's surface. The negative effect of surfactants on the skin barrier can be reduced by changing the solution properties. As a dermatologist in the group of patients we encounter in our clinical dermatology practice who recommends face wash products, we thought of conducting this research in order to determine the product contents to identify the products with the highest user satisfaction so that we can easily make the selection of the right product and direct the patients correctly. MATERIALS AND METHODS: We planned to conduct cross-sectional research. Ten facial cleansing products sold on the most popular website that sells dermo-cosmetic products online in our country were selected. In the selection of the website, the criterion of having the most Internet traffic was sought. Internet traffic data was obtained from www.similarweb.com. The classification of the identified key ingredients according to their chemical properties was used on https://cosmeticanalysis.com. Reviews for each of the ten products in total were examined from the most recent date to the oldest. RESULTS: We detected 87 different chemicals in ten different products. These basically consisted of surfactants, emollients (moisturizers), emulsifiers (cleansers), buffering (denaturators), herbal ingredients-antioxidants, solvents, and moisturizers. A total of 30 different surfactants were identified as the main cleaning ingredient in the examined products. Counterfeit product reporting was especially high on expensive products. No correlation was found between the number of surfactants in the products and the positive effects, such as cleansing and acne reduction and increase, and the negative effects, such as dryness, redness, burning, and smoothing/softening (p>0.05). There was a negative correlation between the cleansing effect of the products and the improvement and worsening of acne (p<0.05, p<0.001, respectively). CONCLUSION: The bottom line is that a good facial cleansing product doesn't have to contain a lot of chemicals and surfactants. It should be kept in mind that expensive products may be counterfeit and should question whether the product is original or not on the local product detection system from the barcode number.

Facial Dermatoses in Patients With Blepharitis: a Cross-sectional Prospective Analysis.

Introduction: The relationship between facial dermatoses and blepharitis has been known for a long time. Objectives: We aimed to investigate the frequency of accompanying facial dermatoses in patients with blepharitis and their relationship with the severity of blepharitis. Methods: In this cross-sectional study, 95 patients with blepharitis were examined for attending facial dermatoses. The type of blepharitis, the severity of blepharitis, and the degree of dry eye were determined in the patients. Dermoscopic and microscopic examinations were used in the diagnosis of facial dermatoses. The history of allergic rhinitis was questioned because Demodex species frequently accompany blepharitis, facial dermatoses, and allergic rhinitis patients. Mann-Whitney U test was used compare 2 independent groups. In comparing categorical variables, Pearson chi-Squared, Fishere Exact, and Fisher-Freeman-Holton tests were used. Results: At least 1 facial dermatosis was detected in 84.2% patients, and we did not see any facial dermatosis in 15.8% ones. No patients had acne, which is one of the most common facial dermatoses. The most common facial dermatosis detected in our patients was facial demodicosis (57.9%). It was followed by seborrheic dermatitis (22.1%) and rosacea (12.6%), respectively. In addition, 2.1% of the patients had atopic eyelid dermatitis, 23.2% had a history of allergic rhinitis, and 63.2% had ocular demodicosis. Conclusions: It is essential to perform dermatological examinations of all patients with blepharitis in terms of accompanying facial dermatoses and their early diagnosis.

"Mole removal" on Instagram Hashtags: A Cross-sectional Analysis: Nevus Treatment Methods on Instagram.

INTRODUCTION: With the increase in the use of social media, there is a steady increase in demand for medical, surgical, and cosmetic procedures. Dermatologists and other physicians are leaving their cosmetic practice to non-physician service providers to keep up with the growing demand for cosmetic procedures. OBJECTIVES: To examine the gender, professions, and the method of nevi treatment of the profiles using #bensilme and #moleremoval hashtags on Instagram and to investigate the extent of cosmetic procedures comparing Turkey's situation with other countries. METHODS: In Instagram, the most frequently used hashtags about nevus treatment were scanned by two dermatologists. We recorded profession, gender, country of origin, and the treatment method of nevi of profiles sharing the related posts. RESULTS: The countries with the highest share of the #moleremoval hashtag were the United Kingdom (15%), India (12%), and the United States of America (10.5%), and the proportion of physicians in these countries was 16.7%, 100%, and 71.4%, respectively. In the non-physician group, plasma pen method in our country is the most used method (Turkey: 97.9%, world: 75% respectively), but the use of radiofrequency cautery (world: 12.5%, Turkey: 1% respectively) and cryo pen (world: 7.5%, Turkey: 0.0%) methods were significantly more abroad. CONCLUSIONS: We demonstrated that non-physicians mostly perform nevus destruction procedures. Physicians must use social media more actively to share educational, quality, and accurate information. We suggest that the hashtags used by physicians in their social media posts should be chosen from the words used in the folk language.

The effects of vitamin B12, vitamin D, ferritin level, neutrophil/monocyte ratio and some blood parameters on genital warts presence, the number of lesions, and recurrence rates.

The relationships between cancer caused by HPV and some vitamins, as well as leucocytes and their ratios, have been investigated in the literature. Our aim is to evaluate these relationships at the level of genital wart in terms of the investigated parameters and lesion numbers. Data were obtained from 98 and 94 patients for groups one and two, including warts patients and healthy people respectively. The Neutrophil/Monocyte ratio and lesion numbers in the warts patients were reported and analysed in terms of vitamin B12 and D, ferritin and leucocytes. A correlation was established between lesion numbers, age and midcorpuscular volume (p <0.05). There was no correlation between lesion numbers and recurrence. According to the comparative analysis, there were differences in terms of ferritin, neutrophil, monocyte, haemoglobin, midcorpuscular volume and neutrophil/monocyte ratio between groups. The cut-off values for neutrophil, monocyte and N/M ratios were 56.45, 4.91 and 7.825 respectively. While our study showed that wart development may be affected by blood ferritin levels and in this situation, midcorpuscular volume, neutrophil, monocyte and N/M ratios may change, a relation was found between lesion numbers and age and mean midcorpsucular volume values only. However, further studies are needed to clarify this issue.

Evaluation of trace elements, calcium, and magnesium levels in the plasma and erythrocytes of patients with essential hyperhidrosis.

BACKGROUND: Essential hyperhidrosis is a disease that expresses itself with excessive sweating in palmar, plantar, axillary, and craniofacial regions. The etiopathogenesis of the disease, which has particular importance because of leading to psychosocial morbidity, could have not been completely elucidated. In previous studies, it has been shown that oxidative stress might play a role in the pathogenesis. AIMS: Assessing the levels of trace elements such as Se, Zn, Cu, Fe, and Mg that have an important role in oxidative stress, as well as Ca and Mg that have an important role in membrane physiology, in patients with essential hyperhidrosis. MATERIALS AND METHODS: Blood samples taken from the patient group with essential hyperhidrosis (42) and the control group (37) were separated into plasma and erythrocytes, and the levels of the bioelements were measured by use of ICP-OES device. RESULTS: Erythrocyte levels of Se, Fe, Cu, Zn, Ca, and Mg were detected significantly higher in patients with essential hyperhidrosis. Furthermore, plasma levels of Cu, Ca, and Mg were significantly lower in patients with essential hyperhidrosis. Plasma levels of Se, Fe, and Zn showed no statistical difference between two groups. DISCUSSION: It was thought that the high levels of Cu and Fe in erythrocytes may play a role in increased intracellular oxidative stress, whereas the increase in Se and Zn levels may be secondary to increased oxidative stress. Low extracellular concentrations of Ca and Mg raise the thought that they play a role either enhancing the membrane excitability of eccrine sweat glands or influencing the autonomic nerve system. CONCLUSION: The levels of trace elements, which were determined to be different from the control group, may play a role in the pathogenesis of essential hyperhidrosis either in direct relation with or without oxidative mechanisms.