RESUMO
Chlormethiazole and diazepam as intravenous sedatives were compared in 75 patients undergoing fibre-endoscopic examination of the upper gastrointestinal tract. Diazepam was considered to offer greater reliability and ease of administration. Chlormethiazole wqs found to be a safe drug and did not encourage salivation. Local pain caused by chlormethiazole injection can be abolished by the use of lignocaine. Chlormethiazole may be useful in patients who are hypotensive and who require emergency endoscopy.
Assuntos
Clormetiazol/farmacologia , Diazepam/farmacologia , Endoscopia , Hipnóticos e Sedativos , Adulto , Fatores Etários , Idoso , Pressão Sanguínea/efeitos dos fármacos , Relação Dose-Resposta a Droga , Eletrocardiografia , Feminino , Tecnologia de Fibra Óptica , Hemólise , Humanos , Inalação , Injeções Intravenosas , Intestinos , Pulmão , Masculino , Pessoa de Meia-Idade , Pulso Arterial/efeitos dos fármacos , EstômagoAssuntos
Abortivos/efeitos adversos , Aborto Terapêutico/efeitos adversos , Sabões/efeitos adversos , Abortivos/farmacologia , Adulto , Coagulação Intravascular Disseminada/induzido quimicamente , Feminino , Parada Cardíaca/induzido quimicamente , Hemólise/efeitos dos fármacos , Humanos , Gravidez , Sabões/farmacologiaRESUMO
Paraplegia complicating a block of the coeliac plexus with 6% aqueous phenol for carcinoma of the pancreas is described. The patient had no previous neurological abnormality and it is postulated that vascular ischaemia of the spinal cord was responsible for the sequence of neurological events.