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J Microbiol Methods ; 65(3): 596-603, 2006 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-16316701

RESUMO

A simple biosurfactant-based hydrophobization procedure for poly(vinyl alcohol) (PVA) cryogels was developed allowing effective immobilization of hydrocarbon-oxidizing bacteria. The resulting partially hydrophobized PVA cryogel granules (granule volume 5 microl) contained sufficient number (6.5 x 10(3)) of viable bacterial cells per granule, possessed high mechanical strength and spontaneously located at the interface in water-hydrocarbon system. Such interfacial location of PVA granules allowed high contact of immobilized biocatalyst with hydrophobic substrate and water phase, thus providing bacterial cells with mineral and organic nutrients. As a result, n-hexadecane oxidation efficiency of 51% after 10-day incubation was achieved using immobilized biocatalyst. PVA cryogels with increased hydrophobicity can be used for immobilization of bacterial cultures performing oxidative transformations of water-immiscible organic compounds. Immobilization of in situ biosurfactant producing Rhodococcus bacteria into PVA cryogel is discussed. PVA cryogel granules with entrapped alkanotrophic rhodococcal cells were stable after 10-month storage at room temperature.


Assuntos
Proteínas Sanguíneas , Fibronectinas , Hidrocarbonetos/metabolismo , Álcool de Polivinil , Rhodococcus/fisiologia , Tensoativos/metabolismo , Alcanos/metabolismo , Biodegradação Ambiental , Proteínas Sanguíneas/química , Células Imobilizadas , Criogéis , Criopreservação/métodos , Fibronectinas/química , Hidrogéis , Interações Hidrofóbicas e Hidrofílicas , Oxirredução , Polissorbatos/metabolismo , Rhodococcus/crescimento & desenvolvimento , Rhodococcus/metabolismo
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