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1.
OTO Open ; 7(1): e45, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36998563

RESUMO

Selecting qualified candidates each year for residency positions has become more difficult in recent years, due to the sharp increase in Otolaryngology applicants. Although there are objective measures that can be used to directly compare medical students during the initial screening process, most information in the application is highly subjective and/or variable across institutions. Many programs count the total posters/presentations and publications to gauge scholarship. This measure of quantity may lead to negative bias toward those who have no home program, limited time outside of academics, and/or inadequate resources to engage in volunteer research. Evaluating the quality of research may be superior to quantity. A first-author publication is a viable proxy that demonstrates applicants have developed skills that set them apart from their peers. They likely possess non-clinical, translatable skills including internal motivation, self-regulation, curation of information, and task completion that map closely with qualities that make for excellent residents.

2.
Laryngoscope ; 133(10): 2572-2577, 2023 10.
Artigo em Inglês | MEDLINE | ID: mdl-36625305

RESUMO

OBJECTIVE: To evaluate the impact of age and the American Society of Anesthesiologists (ASA) classification on post operative outcomes as well as the changes in the National Surgical Quality Improvement Program (NSQIP) database reporting of comorbidity index variables in patients with facial fractures. METHODS: The NSQIP database was queried for facial fracture repair CPT codes between 2012 and 2019 and for modified Frailty Index (mFI) and modified Charlson Comorbidity Index (mCCI) variables between years 2006 and 2018. The predominant question analyzed two preoperative risk factors: patient and ASA classification. Chi-square analysis, Kruskal-Wallis, Mann-Whitney, Spearman correlation, and multivariable logistic regression were used to evaluate age and ASA classification with wound dehiscence, superficial surgical site infection (SSSI), deep wound infection (DWI), readmission status, and return to the OR. The reporting of indices variables was evaluated with descriptive statistics. CONCLUSION: In this large database with univariate analysis, patients with a higher ASA classification and older patients experience significantly increased risks of readmission, return to the OR, and longer hospital stays. On multivariate analyses, ASA classes II, III, and IV are independently associated with increased risk of readmission and return to the OR, while controlling for patient age. The reporting of all mFI and mCCI variables were consistent from 2006 to 2010, but after 2011, there has been inconsistent or absent reporting of variables, therefore, conclusions on the impact of comorbidities on facial fracture repair are unreliable. LEVEL OF EVIDENCE: 4 Laryngoscope, 133:2572-2577, 2023.


Assuntos
Complicações Pós-Operatórias , Melhoria de Qualidade , Humanos , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Comorbidade , Bases de Dados Factuais , Modelos Logísticos , Fatores de Risco , Estudos Retrospectivos , Readmissão do Paciente
3.
Facial Plast Surg Aesthet Med ; 25(1): 22-26, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-35759472

RESUMO

Background: Orbital wall fractures are often associated with concomitant ocular injury. In some cases, detection and treatment of such injuries requires ophthalmology evaluation. Study Objective: To identify a change in ocular management as a result of ophthalmology evaluation in patients with orbital wall fractures. Materials and Methods: Retrospective cohort, patients >18 years of age with orbital wall fracture, and prompt evaluation by an ophthalmologist from 2012 to 2020 in a tertiary Level 1 trauma center. Results: Fifty percent of patients had a moderate and/or severe ocular injury. Ophthalmology evaluation led to an ocular management change in 27% of patients. Patients with eyelid laceration, extra-ocular motion (EOM) abnormality, and pupillary defect were more likely to have a change in management. There was no delay of surgical bony fracture management. Conclusion: In patients with midface trauma including orbital wall fractures those with eyelid laceration, EOM abnormality, and pupillary defect were likely to undergo ocular management change as a result of ophthalmology consultation.


Assuntos
Traumatismos Oculares , Lacerações , Fraturas Orbitárias , Humanos , Estudos Retrospectivos , Lacerações/complicações , Traumatismos Oculares/diagnóstico , Traumatismos Oculares/cirurgia , Fraturas Orbitárias/diagnóstico , Fraturas Orbitárias/cirurgia , Encaminhamento e Consulta
4.
Cureus ; 14(10): e30586, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-36420241

RESUMO

Mucosal leishmaniasis (ML) is a rare metastatic complication of Leishmania infection. It has a high potential for destructive and disfiguring complications, namely destruction of nasal architecture and airway compromise. ML is difficult to treat for a variety of reasons, including variable antimicrobial resistance rates between species, as well as between endemic areas geographically. There are several treatment options available, which are discussed here. In the majority of cases, a nuanced approach to treatment is required based on speciation and geography. Importantly, the treatment of ML requires a multi-disciplinary approach. We present a patient with a history of cutaneous leishmaniasis who presented with signs and symptoms concerning ML, but due to the COVID-19 global pandemic diagnostic testing was not possible, was treated empirically under clinical suspicion of ML with good results.

5.
Trauma Case Rep ; 39: 100648, 2022 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-35571576

RESUMO

Background: Blunt trauma to the face, head and neck is frequently encountered in violent assaults (Brink, 2009 [1]). There can be trauma to the cranium in high energy mechanisms, though interpersonal trauma is less likely to be associated with traumatic brain injury (TBI) (Salentijn et al., 2014 [2]). Case report: We describe severe soft tissue facial trauma, ocular trauma, subdural and epidural hematomas as well as calvarial fractures, orbital floor and zygomaticomaxillary complex (ZMC) fracture following assault with a meat tenderizer. Due to the unique mechanism of trauma and the extent of injury including TBI coordination of care involved many teams. The patient was treated, then discharged to a skilled nursing facility with subsequent discharge to home. He has continued neurocognitive improvement but loss of vision in the left eye. Conclusion: Violent trauma with a meat tenderizer can lead to significant soft tissue trauma, facial fractures, calvarial fractures and TBI.

6.
Ophthalmic Plast Reconstr Surg ; 38(4): e122-e124, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35353774

RESUMO

We present a patient who underwent orbital fracture repair complicated by retrobulbar hemorrhages twice within the first postoperative week. The suspected cause is continuous positive airway pressure (CPAP) use with inappropriate patient-modified settings. The most likely mechanism of action was venous congestion from the extrinsic positive pressure, similar to Valsalva maneuvers increasing orbital vasculature pressure. In our patient, because his orbital blood vessels had recently been cauterized, they were too fragile to handle the engorgement and bled, leading to a retrobulbar hemorrhage. It is possible that at a lower CPAP setting, the vascular congestion would not have been as severe and caused bleeding. We recommend routinely asking patients about CPAP use before orbital surgeries and instructing patients to stop CPAP usage for 1 week after any orbital surgeries if medically cleared.


Assuntos
Fraturas Orbitárias , Hemorragia Retrobulbar , Pressão Positiva Contínua nas Vias Aéreas/efeitos adversos , Humanos , Órbita , Fraturas Orbitárias/complicações , Fraturas Orbitárias/cirurgia , Hemorragia Retrobulbar/diagnóstico , Hemorragia Retrobulbar/etiologia , Hemorragia Retrobulbar/cirurgia
7.
Facial Plast Surg Aesthet Med ; 24(4): 271-275, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-33847511

RESUMO

Introduction: Nasal obstruction is a common clinical problem. It has become more recognized that the internal and external nasal valves are the areas of greatest resistance. There are changes with aging that can contribute to nasal valve compromise. This study sought to evaluate the utilization of functional rhinoplasty, septoplasty, and inferior turbinate reduction procedures in the Medicare population. Methods: The annual procedure data were obtained from the Part B National Summary Data File from 2000 to 2019. Functional rhinoplasty procedures using current procedural terminology (CPT) for rhinoplasty (30400, 30410, 30420, 30465), septoplasty (30520), and inferior turbinate reduction (30801, 30802, 30130, 30140, 30930) procedures were analyzed. Results: There was increased use of CPT codes 30465, 30410, and 30420 with a decrease in 30400. There was an overall increase in codes 30520 and 30140. When adjusting for the Medicare population per 100,000 enrollees, there was increased use of 30465 and 30140 and decrease in 30520. The charges and payment trends were similar to the overall use of CPT codes. Discussion: There is an overall increase in use of nasal airway procedures including functional rhinoplasty in the aging population.


Assuntos
Obstrução Nasal , Rinoplastia , Idoso , Envelhecimento , Humanos , Medicare , Obstrução Nasal/cirurgia , Rinoplastia/métodos , Conchas Nasais/cirurgia , Estados Unidos
8.
Ear Nose Throat J ; : 1455613211058101, 2021 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-34851159

RESUMO

OBJECTIVES: This study aims to assess characteristics of same-day clinic appointments in a pediatric population at an academic otolaryngology practice. METHODS: Retrospective chart review of patients aged 18 or younger who had same-day clinic appointments between January 1, 2016, and December 31, 2018, at a single academic institution. Demographic data, diagnosis(es), procedures, and operations completed were included in the analysis. RESULTS: There were 363 same-day visits by 322 patients in the 3-year study period. Two hundred sixty-nine (269) of these visits were from new patients. Otitis media and rhinosinusitis were the most frequently coded diagnoses. One hundred forty-four (144) procedures were completed the day of the visit and 169 operations were performed as a result of the same-day visit. If the patient had a procedure or operation performed, they were more likely to have been referred by another provider. CONCLUSIONS: Providing same-day appointments can help provide timely and appropriate otolaryngology specialty care to pediatric patients. Further evaluation is needed to determine the effects on patient satisfaction as well as no-show rates.

9.
Otolaryngol Head Neck Surg ; 164(5): 918-922, 2021 05.
Artigo em Inglês | MEDLINE | ID: mdl-32718239

RESUMO

OBJECTIVES: to Examine the practice characteristics of same-day clinic appointments and the use of same-day appointment scheduling to provide access to care in an otolaryngology-head and neck surgery clinic. METHODS: Retrospective chart review of same-day clinic appointments from January 1, 2016, to December 31, 2018, in patients aged >19 years at a single academic center. Demographic data, diagnoses, procedures completed, and operations completed were analyzed. RESULTS: There were 2696 visits by 2324 patients during the 3-year study period. More men than women (57% vs 43%) made same-day appointments. The mean age was 50.7 years (range, 19-99 years). Sinonasal and otologic diagnoses were the most frequently coded. A total of 1452 procedures were completed on the day of the visit, and 239 operations were completed as a result of the visit. Overall, a broad spectrum of otolaryngology care was delivered within the organizational new patient access goals. DISCUSSION: Access to otolaryngology-head and neck surgery care can be challenging. Many patients will seek care when they feel they need it, and patient conditions can change unexpectedly. Offering same-day scheduling can allow patients timely health care and appropriate care. IMPLICATIONS FOR PRACTICE: Same-day appointment scheduling can provide access to care and urgent care for patients. The department of otolaryngology-head and neck surgery has been able to maintain a high rate of providing new patient appointments within 10 days with this method. Further considerations for the impact of same-day scheduling on no-show rates and patient satisfaction can be evaluated.


Assuntos
Instituições de Assistência Ambulatorial/estatística & dados numéricos , Agendamento de Consultas , Acessibilidade aos Serviços de Saúde/estatística & dados numéricos , Otolaringologia , Centros Médicos Acadêmicos , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Adulto Jovem
10.
OTO Open ; 4(2): 2473974X20932497, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32537555

RESUMO

This study examines associations among publication number, National Institutes of Health (NIH) funding rank, medical school research rank, and otolaryngology department ranks of otolaryngology applicants during the 2018-2019 match cycle. Information regarding 2018-2019 otolaryngology applicants was collected from Otomatch.com and verified via department websites. Information was also collected regarding 2018 NIH funding rank and 2020 US News & World Report research rank of medical schools and otolaryngology departments. T tests and chi-square analyses were performed. Top 40 NIH funding rank, top 40 medical school research rank, and home institution department rank were separately associated with more publications and higher rates of matching into highly reputed otolaryngology departments (all P < .01). Furthermore, applicants who matched into ranked otolaryngology departments averaged significantly more publications (P < .01). Prospective otolaryngology applicants should take into account NIH funding rank, medical school research rank, and otolaryngology department rank, as they are associated with matching into high-ranking institutions.

11.
Am J Otolaryngol ; 40(5): 636-640, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31133361

RESUMO

PURPOSE: This prospective cohort study was completed to evaluate a systematic approach for teaching nasal analysis to otolaryngology-head and neck surgery residents. METHODS: Residents from each post graduate year (PGY) were randomized to the control group or study group. Residents in the study group were given a 10-slide PowerPoint (Microsoft Corp) instruction on nasal analysis using the standard sequence of photographs and anatomic elements to describe in each view. All residents were given the standard sequence of photographs of 3 patients for assessment on nasal analysis. Then 12-14 weeks later all residents were re-evaluated using photographs of 3 new patients. The results were blinded and graded using an 18 point scale modified from a previous publication [1]. RESULTS: Twenty otolaryngology-head and neck surgery residents completed the study. Analysis was performed with and without multivariate regression modeling to adjust for PGY, sex, and number of rhinoplasties performed. The study group had overall higher scores in both the initial and follow up assessment, specifically with subsite-specific dorsal deviation, tip projection, and nostril symmetry. Neither group obtained high scores in facial symmetry, skin thickness, tip shape and contour, and radix position at initial or re-assessment. CONCLUSION: Nasal analysis is a complex task. A lecture on a systemic approach to facial analysis given to a group of residents, who performed significantly better on facial analysis cases than controls. Further research in providing feedback, periods of rehearsal or testing, or focused selected elements with serial exposure can be considered.


Assuntos
Competência Clínica , Educação de Pós-Graduação em Medicina/métodos , Nariz/anatomia & histologia , Otolaringologia/educação , Rinoplastia/educação , Adulto , Estudos de Coortes , Diagnóstico por Computador , Feminino , Humanos , Internato e Residência/métodos , Masculino , Análise Multivariada , Nariz/cirurgia , Estudos Prospectivos , Análise de Regressão , Ensino
12.
Facial Plast Surg Clin North Am ; 27(1): 67-83, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30420074

RESUMO

Successful perioral reconstruction is the result of consideration of both functional and esthetic goals. The lips are complex esthetic units with multiple tissue layers and distinct anatomic landmarks. Reconstruction can be difficult due to variables affecting the defect, such as size, depth, location, and involvement of adjacent subunits. There are many local flaps that can be used to match the complex tissue layers and anatomic landmarks. Use of the same reconstructive principles can be applied to secondary reconstruction to attain a successful outcome. This article focuses on local reconstructive options for defects of the lip and chin.


Assuntos
Queixo , Procedimentos Cirúrgicos Dermatológicos/métodos , Neoplasias Faciais/cirurgia , Lábio , Neoplasias Cutâneas/cirurgia , Retalhos Cirúrgicos , Neoplasias Faciais/patologia , Humanos , Neoplasias Cutâneas/patologia
13.
Otolaryngol Head Neck Surg ; 159(2): 254-257, 2018 08.
Artigo em Inglês | MEDLINE | ID: mdl-29759029

RESUMO

Burnout in modern medicine is becoming more recognized and researched. The objective in this study is to evaluate burnout in a tertiary care academic institution and compare results among faculty, trainees, and advanced practice practitioners (APPs) in a cross-sectional survey using the Maslach Burnout Inventory. Fifty-two surveys were distributed; 44 participants completed the survey (85%): 25 staff physicians (57%), 14 resident physicians (32%), and 5 nurse practitioners (11%). Staff physicians had low emotional exhaustion, moderate depersonalization, and low result for reduced personal accomplishments; trainees reported low emotional exhaustion, high depersonalization, and moderate reduced personal accomplishment; and nurse practitioners reported moderate on all 3 dimensions. There is overall low burnout in this tertiary care academic center of otolaryngologist providers and no difference in rates among the different groups (trainees, APPs, staff). Measures addressing specific deficiencies among dimensions of burnout would be helpful to prevent disintegration of physician satisfaction into burnout.


Assuntos
Esgotamento Profissional/epidemiologia , Profissionais de Enfermagem/psicologia , Otolaringologia , Médicos/psicologia , Adulto , Feminino , Humanos , Masculino , Inquéritos e Questionários
14.
Am J Otolaryngol ; 38(3): 305-308, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28169009

RESUMO

OBJECTIVE: To identify clinical characteristics of pediatric patients that failed nasal steroid therapy for management of chronic nasal obstruction and to evaluate the efficacy of adenoidectomy in this subset of patients. DESIGN: Retrospective chart review. SETTING: Tertiary care academic center. SUBJECTS: Analysis was performed on children that underwent adenoidectomy between 2011 and 2015 for chronic nasal obstruction refractory to nasal steroids. RESULTS: Seventy-four cases were identified. Average age of presentation was 3.6years. Pre-operatively, 25.7% of patients had known asthma, 16.2% reported respiratory allergies, and 20.3% reported use of systemic antihistamines. The most common pre-operative symptoms included mouth breathing (82.4%), nasal congestion (81.1%), snoring (71.6%), and rhinorrhea (37.8%). Average adenoid size was 68% pre-operatively. Ninety-eight percent of patients experienced improvement or resolution of their symptoms following adenoidectomy. CONCLUSIONS: This study demonstrates average rates of respiratory allergies, but high rates of asthma among patients that fail nasal steroid therapy for chronic nasal obstruction. Adenoidectomy is a highly efficacious intervention in this subset of patients.


Assuntos
Adenoidectomia , Tonsila Faríngea/cirurgia , Obstrução Nasal/cirurgia , Esteroides/administração & dosagem , Administração Intranasal , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Obstrução Nasal/tratamento farmacológico , Estudos Retrospectivos , Resultado do Tratamento
15.
Int J Pediatr Otorhinolaryngol ; 93: 68-70, 2017 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-28109500

RESUMO

INTRODUCTION: Preauricular lesions, including tags, pits, sinuses, and cysts are commonly seen. Some studies have shown increased incidence of hearing loss in these patients but other studies have failed to corroborate this finding. The purpose of this study is to evaluate the incidence of hearing loss in patients with isolated preauricular lesions. METHODS: Retrospective chart review of all pediatric otolaryngology patients seen at a tertiary academic center between 2008 and 2014. All patients with the diagnosis code of 744.1 or 701.9 (preauricular skin tag) or 744.46, 744.47, or 744.89 (preauricular pit/fistula/cyst) were included in this study. Medical records were reviewed for clinical, demographic, and audiologic data. RESULTS: Ninety-nine patients, 46 males, 53 females, with preauricular lesions were identified. Twelve were found to have abnormal hearing. Five patients had conductive hearing loss due to underlying Eustachian tube dysfunction. Four patients had sensorineural hearing loss; three of these patients had an enlarged vestibular aqueduct and one patient did not have an identified cause. Three patients had sound field testing or abnormal otoacoustic emissions that suggested hearing loss with no further follow up. CONCLUSION: Children with isolated preauricular lesions with no history of otologic surgery or risk factors for hearing loss may not need audiologic evaluation outside of regular hearing screening. However, there does appear to be a higher association with Eustachian tube dysfunction in these children. Further studies will need to be done to determine whether or not there is an embryological correlation for this finding.


Assuntos
Audiometria , Anormalidades Craniofaciais/complicações , Otopatias/complicações , Orelha Externa/anormalidades , Perda Auditiva/diagnóstico , Criança , Pré-Escolar , Feminino , Seguimentos , Perda Auditiva/epidemiologia , Perda Auditiva/etiologia , Humanos , Lactente , Masculino , Estudos Retrospectivos , Fatores de Risco
16.
Int J Pediatr Otorhinolaryngol ; 89: 25-7, 2016 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-27619023

RESUMO

OBJECTIVE: The best imaging study for evaluation of pediatric hearing loss is debated and it is well known magnetic resonance imaging is more costly than computed tomography. The objective of this study is to evaluate charges of computed tomography temporal bone (CTTB) versus magnetic resonance imaging brain, internal auditory canal/cerebellopontine angle (MRI IAC/CPA), with and without sedation in the pediatric population in order to assess to what extent the charges for the procedure are increased. In addition, differences in need for sedation and duration of sedation will be evaluated. METHODS: All patients, 0-18 years that underwent CTTB or MRI IAC/CPA, between January 2013 through December 2014 within department of otolaryngology. RESULTS: 120 CTTBs (118 non-sedated and 2 sedated) and 51 MRI IAC/CPAs (32 non-sedated and 19 sedated) were performed. Average charge for non-sedated CTTB was $1856. CTTB scan under sedation incurred total additional charges of $2385. Average charges for non-sedated MRI IAC/CPA was $3770. Technical charges for sedated MRI IAC/CPA was $151 lower ($2858) but had additional sedation charges of $2256, a recovery room charge of $250, and additional professional fees of $1496 for total charges of $7621. 37% of MRI IAC/CPAs needed sedation to be completed in comparison to 1.6% of CTTB. CONCLUSION: MRI IAC/CPAs are, on average, twice as costly as CTTBs. Almost 40% of patients need sedation to complete MRI IAC/CPA. These considerations may factor into decision making when choosing imaging modality in evaluation of pediatric hearing loss.


Assuntos
Encéfalo/diagnóstico por imagem , Ângulo Cerebelopontino/diagnóstico por imagem , Sedação Consciente/economia , Honorários e Preços , Perda Auditiva Neurossensorial/diagnóstico por imagem , Imageamento por Ressonância Magnética/economia , Tomografia Computadorizada Multidetectores/economia , Osso Temporal/diagnóstico por imagem , Adolescente , Criança , Pré-Escolar , Surdez/patologia , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Tomografia Computadorizada por Raios X/economia , Estados Unidos
17.
Otolaryngol Head Neck Surg ; 154(6): 1068-72, 2016 06.
Artigo em Inglês | MEDLINE | ID: mdl-26932960

RESUMO

OBJECTIVE: To determine the charges associated with performing combined tympanometry and otoacoustic emissions vs a comprehensive audiogram in the pediatric population and to analyze its implications for future practice. STUDY DESIGN: Retrospective charge analysis. SETTING: Tertiary care academic center. SUBJECTS AND METHODS: Analysis was performed on 538 pediatric patients who underwent audiometric hearing testing from May through October 2014. RESULTS: In total, 401 patients had combined tympanometry and otoacoustic emissions testing and 91 patients underwent a comprehensive audiogram, while 46 patients underwent all 3 tests. The technical and professional charges for combined tympanometry and otoacoustic emissions were $139 and $116, respectively, with an overall charge of $255. The technical and professional charges for an audiogram were $124 and $198, respectively, with an overall charge of $322. CONCLUSION: Objective testing with a combination of tympanometry and otoacoustic emissions charges insurers $67 less than an audiogram. Given the questionable reliability of behavioral audiometry in very young children, this is a factor to consider when choosing the appropriate test. With a large number of pediatric auditory hearing tests performed each year, the cost savings within the health care system could be substantial.


Assuntos
Testes de Impedância Acústica/economia , Audiometria/economia , Emissões Otoacústicas Espontâneas , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , Estudos Retrospectivos
18.
Ear Nose Throat J ; 94(9): E4-6, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-26401682

RESUMO

Noonan syndrome is an autosomal dominant disorder with associated anomalies that include short stature, congenital heart defects, developmental delay, and characteristic facial features among other abnormalities. Articulation deficiency and language delay are often present and require speech therapy. Otitis media and hearing loss have been reported to be common in these patients. We performed a retrospective chart review of pediatric patients who were diagnosed with Noonan syndrome at our tertiary care center from January 1979 through December 2009. We found 19 such patients. Of these, 8 had received single-specialty care at our hospital; it is not known if they had received otolaryngologic care from an outside provider. These 8 patients were not included in our study. The remaining 11 patients-6 boys and 5 girls, aged 1 to 19 years (mean: 9.2)-had all received multidisciplinary care at our institution; 9 of them had received care from an otolaryngologist at our center. Of this group, 7 had history of feeding difficulty, 6 had experienced speech delay that required speech therapy, 6 had undergone placement of a pressure equalization tube, 4 had undergone adenoidectomy with or without tonsillectomy, and 1 had been treated with endoscopic sinus surgery. Although this study is limited by our small number of patients, our results suggest that early otolaryngologist involvement must be considered in the care of children with Noonan syndrome because many have evidence of eustachian tube dysfunction, hearing loss, and speech delay.


Assuntos
Síndrome de Noonan/diagnóstico , Otorrinolaringopatias/diagnóstico , Adenoidectomia , Adolescente , Transtornos da Coagulação Sanguínea/diagnóstico , Criança , Pré-Escolar , Tuba Auditiva/fisiopatologia , Transtornos da Alimentação e da Ingestão de Alimentos/diagnóstico , Feminino , Perda Auditiva Condutiva/diagnóstico , Humanos , Lactente , Transtornos do Desenvolvimento da Linguagem/diagnóstico , Transtornos do Desenvolvimento da Linguagem/terapia , Masculino , Síndrome de Noonan/genética , Otorrinolaringopatias/genética , Otorrinolaringopatias/fisiopatologia , Otorrinolaringopatias/terapia , Estudos Retrospectivos , Tonsilectomia , Adulto Jovem
19.
Immunotherapy ; 1(3): 425-34, 2009 May.
Artigo em Inglês | MEDLINE | ID: mdl-19885385

RESUMO

Autoimmune inner ear disease (AIED) is a rare disease that is diagnosed after clinical suspicion and response to corticosteroids. AIED manifests as progressive, bilateral, although often asynchronous, sensorineural hearing loss and can be associated with vestibular symptoms. Since its description as a defined disease entity in 1979, the initial mainstay of treatment remains high-dose corticosteroids. Several animal models have been developed to assist in determining efficacy of immunosuppression in AIED, and several clinical studies have also investigated the role of both steroid and steroid-sparing treatments. Here we discuss the basic science and clinical research surrounding the history of immunosuppressive therapy in AIED.


Assuntos
Corticosteroides/uso terapêutico , Doenças Autoimunes/tratamento farmacológico , Imunossupressores/uso terapêutico , Doenças do Labirinto/tratamento farmacológico , Doenças Autoimunes/imunologia , Doenças Autoimunes/fisiopatologia , Pesquisa Biomédica , Perda Auditiva Neurossensorial , Humanos , Doenças do Labirinto/imunologia , Doenças do Labirinto/fisiopatologia , Modelos Animais
20.
Am J Otolaryngol ; 29(3): 195-7, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-18439955

RESUMO

OBJECTIVE: The purpose of this report is to demonstrate a unique case of severe bronchial stricture and discuss the associated diagnostic and airway management challenges. STUDY DESIGN: The design was that of a case report. METHODS: A review of the literature was made. RESULTS: A 15-year-old adolescent boy with a history of renal transplantation 1 year prior presented with a 10-day history of progressive cough and shortness of breath necessitating ventilator support. Chest radiograph and computed tomography showed complete whiteout of the left lung with some areas of hyperinflation of the left upper lobe. Subsequent flexible and rigid bronchoscopy noted a narrowed left mainstem bronchus with no evidence of an intact lumen. After failed attempts at medical treatment and dilation, the patient underwent a left pneumonectomy. He was ultimately discharged home in good condition. DISCUSSION: Bronchial strictures are rare phenomenon with oftentimes unclear etiologies. Atresia of bronchi is even rarer, usually occurring in young males, and may go undiagnosed for 30 years until clinical symptoms occur. Treatment of narrowed segments may involve medical treatment of infectious agents, stent placement, dilation, and sleeve resection. Treatment of atresia or severe stricture may necessitate resection of the lung distal to the affected region. CONCLUSION: Bronchial strictures and atresias may go undiagnosed for years before pulmonary symptoms occur. Computed tomography and bronchoscopy with biopsies represent the mainstays of diagnosis. Regional lung hyperinflation and peribronchial translucency may hint at bronchial atresia. Treatment paradigms vary from dilation and stent placement to resection of the affected areas. In the absence of a clear etiology for lung whiteout, severe bronchial stricture or atresia should be considered as a possibility.


Assuntos
Broncopatias/cirurgia , Pneumonectomia/métodos , Adolescente , Brônquios/patologia , Broncopatias/diagnóstico , Broncoscopia , Constrição Patológica , Diagnóstico Diferencial , Fibrose , Humanos , Laringoscopia , Masculino , Metaplasia , Radiografia Torácica , Tomografia Computadorizada por Raios X
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