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OBJECTIVES: The purpose of the study was to assess the precision of cone beam computed tomography (CBCT) in comparison with panoramic radiography in determining the anatomical relationship of inferior alveolar nerve (IAN) with the impacted mandibular third molar. MATERIALS AND METHODS: Twenty patients diagnosed with the following panoramic radiographic markers: darkening of the root, interruption of white line of mandibular canal, diversion of mandibular canal, and narrowing of the roots suggesting a close relationship of roots with the mandibular canal were selected and underwent an additional CBCT to assess the proximity of IAN to mandibular third molar roots. All patients were assessed for loss of sensation or neurosensory deficit in the chin and lower lip during postoperative period by objective and subjective methods. RESULTS: Twenty patients with an average age of 25.4 years (21-39 years) with 21 impacted mandibular third molars were included in this sample. It was found that after the removal of impacted third molars, IAN was not visible in any of the cases and postoperative objective and subjective neurosensory tests showed no signs of neurosensory disturbances. CONCLUSION: The study found that CBCT had limited usefulness in neurovascular bundle exposure prediction, prior to surgical removal of impacted mandibular third molars. The accuracy of radiographic markers in conventional panoramic radiography to predict neurovascular exposure was also limited.
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Immunotherapy is one of the newer entities which is promising, at least can be very much helpful as an adjuvant therapy. This newer modality of the treatment in the field of cancer treatment may be the fourth pillar supporting surgery, chemotherapy, and radiotherapy. Careful selection of patient is the key for success of immunotherapy, which is based on patient's immunological contexture. This review aimed to present the fundamental aspects of tumor immunity and immunotherapy, focused on oral squamous cell carcinoma.
RESUMO
BACKGROUND: The aim of this study was to evaluate the efficacy of 2%, 4% lignocaine, Eutectic Mixture of Local Anesthetics (EMLA) mixture and precaine topical anesthetic agents (with 1:1,000,000 epinephrine) during the extraction of deciduous anterior tooth. METHODS: Eighty patients with preshedding mobility of deciduous anterior tooth were divided randomly into four groups. Lignocaine, in amount of 2% and 4%, precaine and EMLA topical anesthetic agents were applied and the tooth was extracted. VAS has been used to assess the subjective pain while Wong-Baker Faces Scale and SEM Pain Scale have been used to record the objective pain to check the efficacy of these topical anesthetic agents. SPSS ver.17 was used for statistical analysis. Group comparison was done by ANOVA (Fishers F test) and inter comparison was done by Tukeys t-test. RESULTS: Based on the scoring criteria of VAS, SEM and Wong Bakers facial pain scales, precaine had best scores followed by EMLA mixture, 4% lignocaine, and then 2 % lignocaine during extraction of primary anterior teeth with preshedding mobility. CONCLUSIONS: The efficacy of precaine was superior compared to EMLA mixture followed by 4% lignocaine and 2% Lignocaine respectively.