RESUMO
Background: Delirium in critically ill patients is independently associated with poor clinical outcomes. There is a scarcity of published data on the prevalence of delirium among critically ill patients in Saudi Arabia. Therefore, we sought to determine, in a multicenter fashion, the prevalence of delirium in critically ill patients in Saudi Arabia and explore associated risk factors. Methods: A cross-sectional point prevalence study was conducted on January 28, 2020, at 14 intensive care units (ICUs) across 3 universities and 11 other tertiary care hospitals in Saudi Arabia. Delirium was screened once using the Intensive Care Delirium Screening Checklist. We excluded patients who were unable to participate in a valid delirium assessment, patients admitted with traumatic brain injury, and patients with documented dementia in their medical charts. Results: Of the 407 screened ICU patients, 233 patients were enrolled and 45.9% were diagnosed with delirium. The prevalence was higher in mechanically ventilated patients compared to patients not mechanically ventilated (57.5% vs. 33.6%; P < 0.001). In a multivariate model, risk factors independently associated with delirium included age (adjusted odds ratio [AOR], 1.021; 95% confidence interval [CI], 1.01-1.04; P = 0.008), mechanical ventilation (AOR, 2.39; 95% CI, 1.34-4.28; P = 0.003), and higher severity of illness (AOR, 1.01; 95% CI, 1.001-1.021; P = 0.026). Conclusion: In our study, delirium remains a prevalent complication, with distinct risk factors. Further studies are necessary to investigate long-term outcomes of delirium in critically ill patients in Saudi Arabia.
RESUMO
BACKGROUND: The severity of bronchial asthma has been associated with increased body mass index (BMI) in several studies. We studied obesity in the asthmatic population and its possible correlation with spirometric variables. METHODS: We reviewed the medical records of 200 patients who underwent spirometry and were followed up in a pulmonary clinic for asthma. Ninety patients fulfilled the inclusion criteria. Patients were divided into Group? (forced expiratory volume in 1 second [FEV1] = 80%, n = 64) and Group II (FEV1 60% to 79%, n = 26). Patients with BMI = 30 were labeled as obese. In each group, correlates of BMI and forced expiratory flow, midexpiratory phase (FEF25%-75%) were analyzed with linear regression. RESULTS: The mean ages were 33.9 -/+ 13 years and 33.73 -/+ 10 years in Groups I and II, respectively. The mean BMI was 30.2 +/ 6 (Group I) and 30.36 -/+ 6 (Group II). BMI = 30 was seen in 56.7% of patients in Group I and 53.3% in Group II. BMI did not correlate with spirometric variables in both groups. FEF25%-75% correlated with FEV1 and FEV1:forced vital capacity (FVC) in Group I (P = .003 and .0001, respectively) and FEV1:FVC in Group II (P = .0001). In Group 1, 38% of the patients had FEF25%-75% less than 80%. CONCLUSION: Although obesity was prevalent in asthmatic patients, BMI did not correlate with any of the spirometric variables. A significant number of patients with normal FEV1 had impaired midflow rates that may reflect ongoing small airway inflammation.