Evaluating the effectiveness of laser hair reduction using a home use laser in comparison to a Diode laser.

BACKGROUND: Lasers of different wavelengths have been developed for use in permanent hair reduction. An increase in the manufacturing of home-use laser hair removal devices allows for these treatments to be performed in the comfort of your own home at an affordable cost. OBJECTIVE: To evaluate the effectiveness of permanent hair reduction using a Diode laser in comparison to the Silk'n™ Flash and Go Lux (475-1200 nm) home-use laser. METHODS: Fifteen females received six axillae laser hair removal treatments at two to four-week intervals using either a professional laser or home-use laser device. Photographs and hair counts were taken before each treatment and at a three week follow up. A T-test was used to evaluate statistical significance, and regression analysis to determine a difference in the effects. Pain scores and side effects were recorded by a visual analogue scale in a satisfaction questionnaire. RESULTS: The professional laser showed an overall hair reduction of 85% on the right axilla and 88% on the left axilla. The home-use laser showed an overall reduction of 52% on the right axilla and 46,3% on the left axilla. Mild side effects were experienced for both laser devices. There were no serious adverse effects reported, safety features are effective to a certain extent. CONCLUSION: The Flash & Go Lux home-use laser can effectively reduce hair at a slower rate than the Diode laser. The home-use laser device offers protection against accidental exposure to light and use on darker skin types. Risks of retinal damage due to long-term exposure to home-use laser light are still cause for concern.

Diarrhoeal prevalence and handwashing practices of children attending early childhood development centres in KwaZulu-Natal, South Africa.

Background: Diarrhoea, a leading cause of childhood morbidity and mortality, spread through contaminated food or water or from person to person, is a major cause of hospitalisation in South African children. Aim: To determine if hygiene practices of parents or guardians and early childhood development centre (ECD) educators contributed to diarrhoea in children attending the centres. Setting: The study was conducted at ECD centres in Mpumalanga Township of KwaZulu-Natal province, South Africa. Methods: A descriptive cross-sectional study was conducted at 10 ECD centres. Parents or guardians (n = 385) and educators (n = 121) answered self-administered questionnaires. Frequencies, bivariate associations and multivariate regression modelling were conducted. Results: The prevalence of diarrhoea in children ≤ 5 years was 67.3%. Most parents or guardians washed their hands after defecating and handling a child's faeces as well as before preparing food. Handwashing after urination was low. Washing of children's hands after these events was lower. Although all educators reported always washing the child's hands after defecating and before handling or eating food, they were less likely to wash the children's hands after urination (p = 0.003). Childhood diarrhoea was associated with the type of toilet, households with pit latrines having a higher prevalence of diarrhoea (p < 0.001). It was also associated with washing of children's hands after urination (p = 0.014), before handling or eating food (p = 0.001) and with increased number of children in the household (p = 0.001). Conclusion: In this population, the high prevalence of diarrhoea is related to the number of children in a household and handwashing practices. Contribution: This study highlights the importance of handwashing practices in the prevention of diarrhoea in children.

Back pain in pregnant women attending an antenatal clinic in KwaZulu-Natal, South Africa.

BACKGROUND: Back pain is not uncommon in pregnant women, but it is often under-reported and can be disabling. International studies report a high prevalence of back pain, especially in the last trimester. Little is known about the prevalence of back pain in South African pregnant women. AIM: To determine the prevalence and risk factors of back pain in a cohort of pregnant women. SETTING: Public primary healthcare clinics and the eThekwini municipality of KwaZulu-Natal (KZN), South Africa. METHODS: A descriptive cohort design was used to survey pregnant women (n = 303) over the course of their pregnancy. Data were collected at the first antenatal visit and again in the third trimester. Participants gave consent and ethical clearance was obtained from an institutional research ethics committee, from the eThekwini Health District and KZN Provincial Department of Health. RESULTS: The respondents were young Black African women (mean age of 25.8 (± 6.0), who were mostly unemployed (70.7%), and resided in a resource poor setting. Back pain prevalence at the first antenatal visit and the third trimester was 12.4% (n = 35) and 10.9% (n = 5), respectively. This condition was associated with carrying water and residing in a hostel or an employee's property. Being single was associated with less risk for developing back pain. CONCLUSION: The prevalence of back pain was low in this cohort of women, yet it resulted in a negative impact on the women's ability to cope with daily life. CONTRIBUTION: This is one of the first studies to describe back pain in a South African pregnant population.

Circulating soluble fms-like tyrosine kinase-1, soluble endoglin and placental growth factor during pregnancy in normotensive women in KwaZulu-Natal, South Africa.

BACKGROUND: Based on the increased pre-eclampsia and HIV antenatal incidence in South Africa, we determined the angiogenic profiles due to its mechanistic link in preeclampsia development, throughout uncomplicated pregnancies in HIV positive and negative women. OBJECTIVE: To determine the angiogenic profiles throughout uncomplicated pregnancies in HIV positive and HIV negative women. We explored possible correlations between angiogenic serum levels and selected maternal characteristics (HIV status, gestational age, maternal factors, and pregnancy outcomes). METHOD: This study was conducted at a primary health care facility in Durban, South Africa. Forty-six pregnant women aged 18-45 years, were enrolled at 10-20, 22-30 and 32-38 weeks' gestation, respectively through convenient sampling. Serum samples were collected and quantitatively evaluated using ELISAs. Clinical and epidemiological data were analysed using STATA (version 14). A probability level of p < 0.05 was considered statistically significant. RESULTS: Of those enrolled, 28.3% were nulliparous, 82% were HIV positive and none developed pre-eclampsia. Systolic and diastolic blood pressure increased slightly throughout pregnancy. Fluctuating angiogenic and anti-angiogenic levels were demonstrated during pregnancy. CONCLUSION: This study contributes to the current angiogenic knowledge in normotensive pregnancies, and may assist as a reference range against which these factors may be compared in HIV complicated pregnancies.

Food-borne disease prevalence in rural villages in the Eastern Cape, South Africa.

BACKGROUND:  The highest burden of food-borne diseases is in Africa. Despite this, food safety does not seem to be a major concern in many African countries. There is also a lack of concern within rural areas of South Africa. AIM:  The aim of this study was to determine the prevalence of food-borne diseases in rural areas in the Eastern Cape, South Africa, by comparing data obtained from a cross-sectional survey and clinic records. SETTING:  The study was conducted in Ncera, Mpongo and Needscamp villages in the Eastern Cape, South Africa. METHODS:  In the first phase of the study, a random sample of household heads (n = 87) were interviewed to determine the prevalence of food-borne diseases between 2012 and 2014. In the second phase, registers from clinics serving the villages were screened for food-borne disease cases during the same time period. RESULTS:  A total of 109 (27.3%) household members fell ill because of food-borne diseases. Half (n = 56; 51.3%) of the respondents who fell ill because of food-borne diseases did not seek medical treatment for their illness. Of those who sought treatment, 19 (46%) attended primary health care clinics. However, examination of the clinic registers showed only four recorded cases of food-borne diseases. CONCLUSION:  The prevalence of food-borne diseases in rural villages in the Eastern Cape, South Africa, was reported as high but the records in clinic registers are low, indicating a gap in the health care system. Monitoring of these diseases needs to improve.

Antimicrobial Activity, Phenolic Content, and Cytotoxicity of Medicinal Plant Extracts Used for Treating Dermatological Diseases and Wound Healing in KwaZulu-Natal, South Africa.

Medicinal plants used for wound healing and skin diseases are the key to unlocking the doors to combating problematic skin diseases as resistance of pathogens to pharmaceuticals and allopathic management continues to increase. The study aimed at investigating the antimicrobial efficacies, phenolic content, and cytotoxicity effects of 11 medicinal plant extracts commonly used for treating skin conditions and wound healing in traditional medicine within KwaZulu-Natal. Eleven plant species were separated into different plant parts (bulbs, roots, leaves) and extracted with different solvents. The extracts were assessed for antimicrobial activity against six Gram-positive and seven Gram-negative bacterial strains and four fungi commonly associated with skin conditions using disc diffusion and microdilution techniques. The aqueous methanolic extracts were screened for phenolic content while cytotoxicity tests were performed on all extracts using the brine shrimp lethality and tetrazolium-based colorimetric (MTT) assays. Extracts from Aloe ferox, A. arborescens, and Hypericum aethiopicum were the most active against almost all of the tested bacterial and fungal strains. All plant species exhibited some degree of antimicrobial activity. Total phenolic levels, flavonoids and tannins were also higher for A. ferox, followed by A. arborescens and H. aethiopicum, respectively. The cytotoxicity results of all plant extracts were in the range of 90-100% survival after 24 h in the brine shrimp assay. Extracts considered lethal would demonstrate >50% shrimp death. The MTT cytotoxicity test yielded LC50 values of >1 mg/mL on all extracts indicating that they are not cytotoxic. The observed antimicrobial efficacy demonstrated by some plant species and the general lack of cytotoxic effects on all the tested extracts presents some promising and beneficial aspects of these medicinal plant extracts in the treatment of skin diseases and wound healing. The two Aloe species and H. aethiopicum were among the best extracts that exhibited consistently good antimicrobial activity and warrants further investigations and possible isolation of bioactive principles.

Cervical cancer screening among university students in South Africa: a theory based study.

INTRODUCTION: Cervical cancer is a serious public health problem in South Africa. Even though the screening is free in health facilities in South Africa, the Pap smear uptake is very low. The objective of the study is to investigate the knowledge and beliefs of female university students in South Africa. METHODS: A cross sectional study was conducted among university women in South Africa to elicit information about knowledge and beliefs, and screening history. RESULTS: A total of 440 students completed the questionnaire. The average age of the participants was 20.39 years (SD  = 1.71 years). Regarding cervical cancer, 55.2% (n = 243) had ever heard about it. Results indicated that only 15% (22/147) of the students who had ever had sex and had heard about cervical cancer had taken a Pap test. Pearson correlation analysis showed that cervical cancer knowledge had a significantly negative relationship with barriers to cervical cancer screening. Susceptibility and seriousness score were significantly moderately correlated with benefit and motivation score as well as barrier score. Self-efficacy score also had a moderate correlation with benefit and motivation score. Students who had had a Pap test showed a significantly lower score in barriers to being screened compared to students who had not had a Pap test. CONCLUSION: This study showed that educated women in South Africa lack complete information on cervical cancer. Students who had had a Pap test had significantly lower barriers to cervical cancer screening than those students who had not had a Pap test.

Human Papillomavirus vaccination acceptability among female university students in South Africa.

BACKGROUND: The objectives of this present study were to assess the awareness of cervical cancer and its risk factors among female undergraduates in South Africa, and to determine the their level of acceptability of Human Papillomavirus (HPV) vaccination. MATERIALS AND METHODS: This cross-sectional study was conducted in March 2013 among 440 full time undergraduate female students. RESULTS: Of those students who never had sex (n=163), 96 (58.9%) had ever heard of cervical cancer and only 12 students (12.5%) knew that HPV causes cervical cancer. More than a third (35.4%) of the students correctly said that sexual intercourse before age of 18 years is a risk factor for cervical cancer and 55.2% of the students knew about the Pap smear test which is used for screening cervical cancer. The majority (77.3%) were willing to accept HPV vaccination. Results revealed that students who knew about the Pap smear test, and were aware that having multiple sex partners, sexual intercourse before the age of 18 years, smoking and having contracted any STDs are risk factors for cervical cancer were more likely to accept HPV vaccination compared to other groups. CONCLUSIONS: The general knowledge of South African female university students about cervical cancer is not sufficient but they have positive attitudes toward getting vaccinated with the HPV vaccine.

Contraceptive practices in the era of HIV/AIDS among university students in KwaZulu-Natal, South Africa.

University students as a population of young adults are reportedly at a higher risk of acquiring sexually transmitted infections and HIV infection than the general public due to their higher levels of sexual experimentation and unsafe sexual practices. The objective of this cross-sectional study was to find the patterns of contraceptive use among university students at Mangosuthu University of Technology (MUT), KwaZulu-Natal, South Africa. A total of 752 students were selected by stratified random sampling techniques. A self-administered questionnaire probing contraceptive usage and reasons for non-usage was used to collect data. The results were summarized using means (SD) for continuous variables and percentages for categorical variables. Chi-square test was used to find the association between gender and contraceptive use. The mean age of the participants was 21.25 years (SD = 2.99). Fifty-nine percent (n = 442) were sexually active. Of the sexually active students, 90.7% (n = 401) used contraceptives. Among contraceptive users, 90.5% (n = 363) used condoms. Gender was not significantly associated (p = 0.327) with contraceptive use, but there was a significant association between gender and condom use as males used condom more than females (p < 0.001). Eighty-one percent (n = 323) of the sexually active students reported that they had used a contraceptive the last time they had sex. Regarding frequency of contraceptive use, 38.7% (n = 155) reported that they use contraceptives sometimes or rarely. The frequency of contraceptive use was not significantly related to gender (p = 0.305). Among 60 participants those who disapproved of using contraception, 68.3% (n = 41) were afraid that contraception would cause sterility and 6 students reported that contraception would make their partner promiscuous. In conclusion, a large proportion of university students at MUT in South Africa are sexually active and use contraception, but the use may be inconsistent. Thus, more research is needed to create interventions on contraception uptake.

Knowledge, practices, and attitudes of emergency contraception among female university students in KwaZulu-Natal, South Africa.

OBJECTIVE: The purpose of this study is to investigate the knowledge, practices, and attitudes among female university students in South Africa regarding emergency contraceptives (EC). METHODS: A cross-sectional study was conducted among 582 female university students who were selected using multi-stage sampling techniques. Multivariate logistic regression analysis was used to find significant predictors for EC awareness. RESULTS: The average age of the female students was 20.9 years (SD=3.0) and 57.2% were presently sexually active. Overall, 49.8% of the participants reported having heard about EC prior to the study. Regarding sexual activities among the female students, 53.2% reported to have sex, and 21.2% of the sexually experienced students used EC prior to the study. Regarding the effectiveness of EC, 29.5% students said it could be used up to 72 hours after unprotected sexual intercourse, and 8% said it could be used just before sex. About two-thirds (61.8%) would recommend the use of EC and 63.2% would use it if they needed. The multivariate analysis indicated that students who were older (>20 years), presently sexually active, and living with their parents were more likely to be aware of EC (p<0.05). CONCLUSION: The students' knowledge and utilization of EC were low. Health education and promotion should be targeted towards these students, and the EC services should be offered on campus.

Do parents still matter regarding adolescents' alcohol drinking? Experience from South Africa.

The purpose of this cross-sectional study was to improve our understanding of adolescents' perceptions of parental practices relating to their (adolescents') alcohol use. A total of 704 students were conveniently selected and completed self-administered questionnaires. More than half (54%) of the adolescents reported that they had consumed alcohol at some time in their life. Parental marital status was significantly associated with whether adolescents ever consumed alcohol or not (p < 0.05). A large number of mothers/female guardians (66.3%) and fathers/male guardians (69.3%) did not allow alcohol use at home. More mothers (54.6%) and fathers (65.3%) were not aware of their adolescents' alcohol consumption (p < 0.05). Adolescents were more likely to use alcohol when they reported that they had often seen either their father or mother drunk or both (p < 0.05). There were also significant associations between parents' views against alcohol use and their adolescents' alcohol use (p < 0.05). Prevalence of alcohol uptake was quite high among these adolescents. Compulsory parenting programmes and skills development should be practiced by education, health, cultural and religious groups. Parents should be motivated to delay the age at which their children are initiated into alcohol use and be provided with guidance on how to counteract social pressures.