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2.
Sci Rep ; 14(1): 2964, 2024 Feb 05.
Artigo em Inglês | MEDLINE | ID: mdl-38316793

RESUMO

Precursory phenomena to earthquakes have always attracted researchers' attention. Among the most investigated precursors, foreshocks play a key role. However, their prompt identification with respect to background seismicity still remains an issue. The task is worsened when dealing with low-magnitude earthquakes. Despite that, seismology and, in particular real-time seismology, can nowadays benefit from the use of Artificial Intelligence (AI) to face the challenge of effective precursory signals discrimination. Here, we propose a deep learning method named PreD-Net (precursor detection network) to address precursory signal identification of induced earthquakes. PreD-Net has been trained on data related to three different induced seismicity areas, namely The Geysers, located in California, USA, Cooper Basin, Australia, Hengill in Iceland. The network shows a suitable model generalization, providing considerable results on samples that were not used during the network training phase of all the sites. Tests on related samples of induced large events, with the addition of data collected from the Basel catalogue, Switzerland, assess the possibility of building a real-time warning strategy to be used to avoid adverse consequences during field operations.

3.
IEEE J Biomed Health Inform ; 27(10): 4649-4659, 2023 10.
Artigo em Inglês | MEDLINE | ID: mdl-37018305

RESUMO

New technologies are transforming medicine, and this revolution starts with data. Usually, health services within public healthcare systems are accessed through a booking centre managed by local health authorities and controlled by the regional government. In this perspective, structuring e-health data through a Knowledge Graph (KG) approach can provide a feasible method to quickly and simply organize data and/or retrieve new information. Starting from raw health bookings data from the public healthcare system in Italy, a KG method is presented to support e-health services through the extraction of medical knowledge and novel insights. By exploiting graph embedding which arranges the various attributes of the entities into the same vector space, we are able to apply Machine Learning (ML) techniques to the embedded vectors. The findings suggest that KGs could be used to assess patients' medical booking patterns, either from unsupervised or supervised ML. In particular, the former can determine possible presence of hidden groups of entities that is not immediately available through the original legacy dataset structure. The latter, although the performance of the used algorithms is not very high, shows encouraging results in predicting a patient's likelihood to undergo a particular medical visit within a year. However, many technological advances remain to be made, especially in graph database technologies and graph embedding algorithms.


Assuntos
Aprendizado de Máquina , Telemedicina , Humanos , Aprendizado de Máquina Supervisionado , Bases de Dados Factuais , Probabilidade , Algoritmos
4.
IEEE J Biomed Health Inform ; 26(10): 4869-4879, 2022 10.
Artigo em Inglês | MEDLINE | ID: mdl-34648462

RESUMO

Nowadays, predictive medicine begins to become a reality thanks to Artificial Intelligence (AI) which allows, through the processing of huge amounts of data, to identify correlations not perceptible to the human brain. The application of AI in predictive diagnostics is increasingly pervasive; through the use and interpretation of data, the first signs of some diseases (i.e. tumours) can be detected to help physicians make more accurate diagnoses to reduce the errors and develop methods for individualized medical treatment. In this perspective, salivary gland tumours (SGTs) are rare cancers with variable malignancy representing less than 1% of all cancer diagnoses and about 5% of head and neck cancers. The clinical management of SGTs is complicated by a high rate of preclinical diagnostic errors. Today, fine needle aspiration cytology (FNAC) represents the primary diagnostic tool in the hands of clinicians. However, it provides information that about 25% of cases are dubious or inconclusive, complicating therapeutic choices. Thus, finding new tools supporting clinicians to make the right choices in doubtful cases is necessary. This research work presents and discusses a Deep Learning-based framework for automatic segmentation and classification of salivary gland tumours. Furthermore, we propose an explainable segmentation learning approach supporting the effectiveness of the proposed framework through a per-epoch learning process analysis and the attention map mechanism. The proposed framework was evaluated with a collected CT dataset of patients with salivary gland tumours. Experimental results show that our methodology achieves significant scores on both segmentation and classification tasks.


Assuntos
Aprendizado Profundo , Neoplasias das Glândulas Salivares , Inteligência Artificial , Humanos , Medicina de Precisão , Estudos Retrospectivos , Neoplasias das Glândulas Salivares/diagnóstico por imagem , Neoplasias das Glândulas Salivares/patologia
5.
Biosens Bioelectron ; 196: 113696, 2022 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-34655970

RESUMO

Marine waters are becoming contaminated by diverse pollutants at a fast rate, and detection of these water pollutants has become a major concern in recent years. Among these, mercury is considered the most toxic element for human health. At present, despite the commonly used methods for its detection are accurate, they often require sophisticated equipments, have relatively high costs, are demanding and time-consuming. Herein a novel solution to detect mercury (II) pollution in sea water is proposed, and an easy and portable detection method has been developed. Indeed, a hydrophobin based chimera able to both adhere to polystyrene multiwell plates and bind mercury (II) with a consequent fluorescent decrease was designed. The chimera was the recognition element in a fluorescence-based biosensor able to detect mercury (II) in the nM range. Indeed, this biosensor specifically measure Hg2+ concentration also in the presence of other metals, reaching a limit of detection of 0.4 nM in tap water and 0.3 nM in sea water. Moreover, the developed biosensor was coupled to machine learning methodologies with the big advantage of predicting mercury concentration levels without the use of classical reader devices, thus allowing in situ monitoring of sea pollution by non-skilled personnel.


Assuntos
Técnicas Biossensoriais , Mercúrio , Poluentes Químicos da Água , Poluentes da Água , Humanos , Limite de Detecção , Aprendizado de Máquina , Mercúrio/análise , Poluentes Químicos da Água/análise
6.
Inf Syst Front ; 23(6): 1467-1497, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33935585

RESUMO

The first few months of 2020 have profoundly changed the way we live our lives and carry out our daily activities. Although the widespread use of futuristic robotaxis and self-driving commercial vehicles has not yet become a reality, the COVID-19 pandemic has dramatically accelerated the adoption of Artificial Intelligence (AI) in different fields. We have witnessed the equivalent of two years of digital transformation compressed into just a few months. Whether it is in tracing epidemiological peaks or in transacting contactless payments, the impact of these developments has been almost immediate, and a window has opened up on what is to come. Here we analyze and discuss how AI can support us in facing the ongoing pandemic. Despite the numerous and undeniable contributions of AI, clinical trials and human skills are still required. Even if different strategies have been developed in different states worldwide, the fight against the pandemic seems to have found everywhere a valuable ally in AI, a global and open-source tool capable of providing assistance in this health emergency. A careful AI application would enable us to operate within this complex scenario involving healthcare, society and research.

7.
Neural Comput Appl ; 33(19): 12591-12604, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33879976

RESUMO

The outbreak of a global pandemic called coronavirus has created unprecedented circumstances resulting into a large number of deaths and risk of community spreading throughout the world. Desperate times have called for desperate measures to detect the disease at an early stage via various medically proven methods like chest computed tomography (CT) scan, chest X-Ray, etc., in order to prevent the virus from spreading across the community. Developing deep learning models for analysing these kinds of radiological images is a well-known methodology in the domain of computer based medical image analysis. However, doing the same by mimicking the biological models and leveraging the newly developed neuromorphic computing chips might be more economical. These chips have been shown to be more powerful and are more efficient than conventional central and graphics processing units. Additionally, these chips facilitate the implementation of spiking neural networks (SNNs) in real-world scenarios. To this end, in this work, we have tried to simulate the SNNs using various deep learning libraries. We have applied them for the classification of chest CT scan images into COVID and non-COVID classes. Our approach has achieved very high F1 score of 0.99 for the potential-based model and outperforms many state-of-the-art models. The working code associated with our present work can be found here.

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