RESUMO
Introduction: The main objective of this article is to analyse the reasons why the 2021 European Super League project failed. The authors ask whether, in addition to the popular clamour against a semi-closed competition, it was the combination of geopolitical interests of the different actors currently involved in European elite football that prevented the project from going ahead. Methods: The main methodological framework is based on a case study, which follows an Stakian approach. To do so, on the one hand, a historiographical analysis of the case has been done; on the other hand, authors have complemented this case study with an analysis of 23 pieces of news published on the website of five mainstream newspapers (from April to June 2021) from those countries with the most significant European football leagues: The United Kingdom (The Guardian), Spain (El País), France (Le Monde), Italy (La Repubblica) and Germany (Der Spiegel). To supplement the analysis of this phenomenon, authors have also considered other relevant news published in other mainstream press or news agencies (such as The New York Times, Politico, The Yorkshire Post, The Times, Marca, Bloomberg and Reuters). Results and Discussion: The authors conclude that, while financially the Super League debate has not been closed, in defending the current business and competition model of European football, UEFA has had the complicity of owners and shareholders of the founding clubs outside of their traditional historical roots, as well as governments that have made football an asset because of their geopolitical positioning, such as Qatar and the UK post-Brexit.
RESUMO
The reactions of aryl-stabilized sulfur ylides with organoboranes has been studied under a variety of conditions. At 5 or -78 degrees C, the reaction with Et3B gave a mixture of the first and second homologation products, but at -100 degrees C, only the first homologation product was obtained even with just 1.1 equiv of Et3B. Under these optimized conditions, the chiral sulfur ylides (derived from camphor sulfonic acid) with different aryl groups were reacted with Et3B to give the corresponding alcohols (95-98% yield, 96-98% ee) and amines (74-77% yield, >98% ee). The origin of the high enantioselectivity is discussed. The use of nonsymmetrical 9-BBN derivatives was also explored. It was found that whereas primary alkyl substituents gave mixtures of products derived from competing migration of the boron substituent and the boracycle, all other groups resulted in either exclusive migration of the boron substituent (Ph, hexenyl, i-Pr) or exclusive migration of the boracycle (hexynyl, cyclopropyl). The factors responsible for the outcome of the reactions involving a hindered (i-Pr) and an unhindered (propynyl) substituent were studied by DFT calculations. This revealed that, in the case of an unhindered substituent, the conformation of the ate complex is the dominant factor whereas, in the case of a hindered substituent, the barriers to interconversion between the conformers of the ate complex and subsequent migration control the outcome of the reaction.
RESUMO
[reaction: see text] An enantioselective preparation of the four diastereomeric 3-amino-2,3,6-trideoxy-hexoses, key components of anthracycline antibiotics, has been developed. Sharpless catalytic asymmetric epoxidation of the (2E)-2,5-hexadien-1-ol, regioselective ring opening with azide, followed by convenient functional group transformations, afforded the key aldehydes cis- or trans-6 in any configuration. The diastereoselective addition of methylmetal reagents to these aldehydes followed by ozonolysis gives access in a completely stereocontrolled manner to the four isomeric trideoxyaminosugars.