[Evoked otoacoustic emissions using clicks in detection of deafness in young children]. / Les oto-émissions acoustiques provoquées (OEAP) par des transitoires dans le dépistage de la surdité du jeune enfant.

Click-evoked otoacoustic emissions (EOAEs) are sounds emitted by the cochlea due to active outer hair cell contraction following stimulation of the stereocilia. The purpose of this study was to evaluate the use of testing for EOAEs as a valid auditory screening method in newborns, and 1074 healthy fullterm babies (2148 ears) with an Apgar score higher than 8 at birth were examined. EOAEs were elicited 4 days after birth and a correlation index higher than 70% represented normal response criteria. If there was no response, EOAEs and brainstem response potentials were tested at the age of one month. On the fourth day after birth. EOAEs specificity and efficiency were found to be 92.3% and 92.4% respectively, while sensitivity was 100%. Specificity and efficiency at one month were rated at 100%. The use of EOAEs offers numerous advantages over traditional auditory screening methods, thus suggesting that this technique is suitable for the mass-screening of infants.

[Short-term reproducibility of acoustic oto-emissions induced by clicks in adults]. / Reproductibilité à court terme des oto-émissions acoustiques provoquées par des clics chez des sujets adultes.

Otoacoustic emissions (OAE) are sounds emitted by the cochlea and recordable in the external ear canal by a miniature microphone. The OAE reflect the existence of an active mechanism within the cochlea. Development of the OAE has spurred much interest because they may used as a valid test for screening and monitoring cochlear changes. The OAE were recorded in 8 normal hearing subjects (15 ears) during nine test sessions under similar conditions. The aim of this work was to study the short-term variability in the amplitude of the emissions. Results of the study indicate that response levels are stable over time in the same ear therefore changes in the response level can be associated with changes in the cochlea.

[Epistaxis and climatic events]. / Epistassi e fattori meteorologici.

Data concerning daily climatic conditions in the area of Perugia during 1987-1990 have been gathered and correlated to daily incidence of idiopathic nose-bleeding observed in the same area and during the same period (1064 patients on the whole). The aim was to verify the relation between climatic events and "epistaxis" phenomenon, relation that has been assumed since a long time but has never been scientifically demonstrated before. Following factors have been estimated: highest and lowest daily temperature, thermal gradient, atmospheric pressure and pressure gradient, relative humidity. Results of statistic correlations show that every climatic factors has a narrow range related to higher incidence of epistaxis and that nose-bleeding is likely conditioned by combination of critical values, as a low temperature with 4 degrees C daily gradient, a 716 mm Hg atmospheric pressure with 2 mm Hg negative gradient, a close to 100% relative humidity.

[Evoked acoustic oto-emissions in patients with diabetes mellitus]. / Etude des oto-émissions acoustiques évoquées chez des patients atteints de diabète sucré.

The purpose of this study was to evaluate the cochlear function in patients with diabetes mellitus by analysis of evoked otoacoustic emissions (EOAE). EOAE were studied in 20 diabetic patients with normal hearing. The parameters used for analysis were the EOAE intensity and amplitude measured per 100 Hz frequency bands between 700 and 4000 Hz These data were compared to the data obtained in a group of non-diabetic control subjects with normal hearing using a Student's t test. The mean EOAE intensity and amplitude by 100 Hz frequency band was significantly lower in diabetic patients than in the control group. This seems to indicate the existence of an alteration in cochlear micromechanics in diabetic patients possibly due to changes in the functioning of the hair cells.

[Results of audiometric and vestibular tests in Cogan syndrome: apropos of a case]. / Résultats des examens audiométriques et vestibulaires dans le syndrome de Cogan: à propos d'un cas.

The authors report on a case of Cogan's syndrome pointing out that hearing loss is due both to cochlear lesions from likely immunitary origin as well as to widespread alterations of auditory central nervous structures. This interpretation allows to explain the apparent discrepancy of the found clinical and instrumental data. From a therapeutic point of view, the authors assert the necessity of an early corticosteroid therapy to obtain some appreciable result. Anyway, they point out how prognosis for auditory function in Cogan's syndrome is often very poor.

[Bacteriology of chronic maxillary sinusitis]. / Zur Bakteriologie der chronischen Sinusitis maxillaris.

132 patients with chronic maxillary sinusitis were included in this bacteriological study of the intrasinus exudate obtained by a radical antrostomy or antral puncture. We found 78.3% aerobes, 21.7% anaerobes, 51.5% gram positive and 48.5% gram negative micro-organisms, but no fungi in 120 cultures. The commonest aerobic species was Haemophylus (20%), whereas Peptococcus and Bacteroides were the commonest anaerobes (10%).