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1.
Appl Opt ; 62(35): 9368-9374, 2023 Dec 10.
Artigo em Inglês | MEDLINE | ID: mdl-38108709

RESUMO

Electron plasma waves can be efficiently excited by a resonant train of ultrashort pulses, spatially separated by a plasma wavelength. Generating a pulse train from a single amplified ultrashort pulse may be challenging when dealing with large beams. Here we discuss a pulse splitting technique using a simple delay mask that can be adapted to large diameter petawatt beams. We show via detailed numerical simulations that unique signatures of electrons accelerated by a resonantly excited wakefield can be obtained from realistic focused double-pulse trains obtained from a single-region delay mask.

2.
Sci Rep ; 13(1): 20681, 2023 Nov 24.
Artigo em Inglês | MEDLINE | ID: mdl-38001120

RESUMO

Shock Ignition is a two-step scheme to reach Inertial Confinement Fusion, where the precompressed fuel capsule is ignited by a strong shock driven by a laser pulse at an intensity in the order of [Formula: see text] W/cm[Formula: see text]. In this report we describe the results of an experiment carried out at PALS laser facility designed to investigate the origin of hot electrons in laser-plasma interaction at intensities and plasma temperatures expected for Shock Ignition. A detailed time- and spectrally-resolved characterization of Stimulated Raman Scattering and Two Plasmon Decay instabilities, as well as of the generated hot electrons, suggest that Stimulated Raman Scattering is the dominant source of hot electrons via the damping of daughter plasma waves. The temperature dependence of laser plasma instabilities was also investigated, enabled by the use of different ablator materials, suggesting that Two Plasmon Decay is damped at earlier times for higher plasma temperatures, accompanied by an earlier ignition of SRS. The identification of the predominant hot electron source and the effect of plasma temperature on laser plasma interaction, here investigated, are extremely useful for developing the mitigation strategies for reducing the impact of hot electrons on the fuel ignition.

3.
Rev Sci Instrum ; 94(9)2023 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-37737696

RESUMO

We report on the commissioning of a full aperture backscatter diagnostics station for the kilojoule, nanosecond high repetition rate L4n laser operating at a wavelength of 527 nm at the Extreme Light Infrastructure (ELI) - Beamlines, Dolni Brezany, Czech Republic. Light scattered back from laser-plasma interaction into the cone of the final focusing lens is captured and split into different channels to measure the signatures of laser plasma instabilities from stimulated Brillouin scattering, stimulated Raman scattering, and two plasmon decay with respect to back scattered energy, its spectrum, and its temporal profile. The performance was confirmed in a commissioning experiment with more than 800 shots at laser intensities ranging from 0.5 × 1013 to 1.1 × 1015 W cm-2. These diagnostics are permanently installed at ELI Beamlines, and can be used to understand the details of laser-plasma interactions in experiments with kJ and 527 nm light. The large number of shots that can be collected in an experimental campaign will allow us to study the details of the laser-plasma interaction with a high level of confidence.

4.
Rev Sci Instrum ; 93(6): 063505, 2022 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-35778032

RESUMO

The shock ignition (SI) approach to inertial confinement fusion is a promising scheme for achieving energy production by nuclear fusion. SI relies on using a high intensity laser pulse (≈1016 W/cm2, with a duration of several hundred ps) at the end of the fuel compression stage. However, during laser-plasma interaction (LPI), several parametric instabilities, such as stimulated Raman scattering and two plasmon decay, nonlinearly generate hot electrons (HEs). The whole behavior of HE under SI conditions, including their generation, transport, and final absorption, is still unclear and needs further experimental investigation. This paper focuses on the development of an experimental platform for SI-related experiments, which simultaneously makes use of multiple diagnostics to characterize LPI and HE generation, transport, and energy deposition. Such diagnostics include optical spectrometers, streaked optical shadowgraph, an x-ray pinhole camera, a two-dimensional x-ray imager, a Cu Kα line spectrometer, two hot-electron spectrometers, a hard x-ray (bremsstrahlung) detector, and a streaked optical pyrometer. Diagnostics successfully operated simultaneously in single-shot mode, revealing the features of HEs under SI-relevant conditions.

5.
Schmerz ; 36(4): 242-247, 2022 Aug.
Artigo em Alemão | MEDLINE | ID: mdl-35301591

RESUMO

Almost everyone is familiar with "tense muscles", but what is muscle tension physiologically behind? Are tense muscles more active; do they have problems relaxing? Are they harder or stiffer than asymptomatic muscles? In this work, current evidence regarding the activity and stiffness of tense neck muscles is presented. Further, measurement methods and their limitations are explained. These limitations reveal the shortcomings of the current knowledge and the need for further research. Finally, a recently funded research project on the measurement of tense muscles is presented.


Assuntos
Técnicas de Imagem por Elasticidade , Tono Muscular , Técnicas de Imagem por Elasticidade/métodos , Humanos , Tono Muscular/fisiologia , Músculo Esquelético/diagnóstico por imagem , Músculo Esquelético/fisiologia , Músculos do Pescoço/diagnóstico por imagem , Músculos do Pescoço/fisiologia
6.
Rev Sci Instrum ; 92(1): 013501, 2021 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-33514221

RESUMO

We report on the optimization of a BremsStrahlung Cannon (BSC) design for the investigation of laser-driven fast electron populations in a shock ignition relevant experimental campaign at the Laser Megajoule-PETawatt Aquitaine Laser facility. In this regime with laser intensities of 1015 W/cm2-1016 W/cm2, fast electrons with energies ≤100 keV are expected to be generated through Stimulated Raman Scattering (SRS) and Two Plasmon Decay (TPD) instabilities. The main purpose of the BSC in our experiment is to identify the contribution to x-ray emission from bremsstrahlung of fast electrons originating from SRS and TPD, with expected temperatures of 40 keV and 95 keV, respectively. Data analysis and reconstruction of the distributions of x-ray photons incident on the BSC are described.

7.
Sci Rep ; 10(1): 5087, 2020 Mar 20.
Artigo em Inglês | MEDLINE | ID: mdl-32198449

RESUMO

Flowing plasma jets are increasingly investigated and used for surface treatments, including biological matter, and as soft ionization sources for mass spectrometry. They have the characteristic capability to transport energy from the plasma excitation region to the flowing afterglow, and therefore to a distant application surface, in a controlled manner. The ability to transport and deposit energy into a specimen is related to the actual energy transport mechanism. In case of a flowing helium plasma, the energy in the flowing afterglow may be carried by metastable helium atoms and long-lived helium dimer ions. In this work a systematic investigation of the optical and spectroscopic characteristics of a supersonic flowing helium plasma in vacuum and its afterglow as function of the helium gas density is presented. The experimental data are compared with numerical modeling of the plasma excitation and helium dimer ion formation supported by a Computational Fluid Dynamic simulation of the helium jet. The results indicate that the plasma afterglow is effectively due to helium dimer ions recombination via a three-body reaction.

8.
J Electromyogr Kinesiol ; 43: 111-117, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30269020

RESUMO

Isometric bite force control, via measures of force accuracy, force steadiness and force proprioception, was assessed in patients with myogenic temporomandibular disorders (TMDs) compared to healthy controls. Twelve people with myogenic TMDs and twelve age- and gender-matched asymptomatic controls performed maximal voluntary contractions (MVC) of unilateral jaw clenching followed by submaximal isometric contractions, with and without visual feedback of force, at 10, 30 50% and 70% MVC. Force performance was assessed with indices of accuracy (mean distance, MD) and precision (standard deviation, SD) and reported as a percentage of the MVC. A mixed-effect model was used to evaluate differences in MVC, MD and SD. The MVC was lower in the TMD group when clenching either ipsilateral or contralateral to the side of greatest pain (p < 0.05). No difference in MD was observed between groups. The SD depended on the interaction between group and painful side (p = 0.04) with the TMD group displaying higher SD when executing the task with the most painful side when compared to the ipsilateral or contralateral sides of the control group. The reduced maximal bite force and force steadiness observed in people with myogenic pain may interfere with masticatory function and should be considered when planning therapeutic interventions for TMDs.


Assuntos
Força de Mordida , Contração Isométrica/fisiologia , Contração Muscular/fisiologia , Transtornos da Articulação Temporomandibular/fisiopatologia , Articulação Temporomandibular/fisiologia , Adulto , Eletromiografia/métodos , Retroalimentação Sensorial/fisiologia , Feminino , Humanos , Masculino , Músculo Masseter/fisiopatologia , Músculo Esquelético/fisiopatologia , Transtornos da Articulação Temporomandibular/diagnóstico
9.
Sci Rep ; 7(1): 8347, 2017 08 21.
Artigo em Inglês | MEDLINE | ID: mdl-28827645

RESUMO

The transport of hot, relativistic electrons produced by the interaction of an intense petawatt laser pulse with a solid has garnered interest due to its potential application in the development of innovative x-ray sources and ion-acceleration schemes. We report on spatially and temporally resolved measurements of megagauss magnetic fields at the rear of a 50-µm thick plastic target, irradiated by a multi-picosecond petawatt laser pulse at an incident intensity of ~1020 W/cm2. The pump-probe polarimetric measurements with micron-scale spatial resolution reveal the dynamics of the magnetic fields generated by the hot electron distribution at the target rear. An annular magnetic field profile was observed ~5 ps after the interaction, indicating a relatively smooth hot electron distribution at the rear-side of the plastic target. This is contrary to previous time-integrated measurements, which infer that such targets will produce highly structured hot electron transport. We measured large-scale filamentation of the hot electron distribution at the target rear only at later time-scales of ~10 ps, resulting in a commensurate large-scale filamentation of the magnetic field profile. Three-dimensional hybrid simulations corroborate our experimental observations and demonstrate a beam-like hot electron transport at initial time-scales that may be attributed to the local resistivity profile at the target rear.

10.
IEEE Int Conf Rehabil Robot ; 2017: 364-368, 2017 07.
Artigo em Inglês | MEDLINE | ID: mdl-28813846

RESUMO

This work aims at estimating the musculoskeletal forces acting in the human lower extremity during locomotion on rough terrains. We employ computational models of the human neuro-musculoskeletal system that are informed by multi-modal movement data including foot-ground reaction forces, 3D marker trajectories and lower extremity electromyograms (EMG). Data were recorded from one healthy subject locomoting on rough grounds realized using foam rubber blocks of different heights. Blocks arrangement was randomized across all locomotion trials to prevent adaptation to specific ground morphology. Data were used to generate subject-specific models that matched an individual's anthropometry and force-generating capacity. EMGs enabled capturing subject- and ground-specific muscle activation patterns employed for walking on the rough grounds. This allowed integrating realistic activation patterns in the forward dynamic simulations of the musculoskeletal system. The ability to accurately predict the joint mechanical forces necessary to walk on different terrains have implications for our understanding of human movement but also for developing intuitive human machine interfaces for wearable exoskeletons or prosthetic limbs that can seamlessly adapt to different mechanical demands matching biological limb performance.


Assuntos
Eletromiografia/métodos , Modelos Biológicos , Músculo Esquelético/fisiologia , Caminhada/fisiologia , Adulto , Fenômenos Biomecânicos , Humanos , Extremidade Inferior/fisiologia , Masculino , Processamento de Sinais Assistido por Computador
11.
Sci Rep ; 7(1): 1479, 2017 05 03.
Artigo em Inglês | MEDLINE | ID: mdl-28469135

RESUMO

Relativistic laser interaction with micro- and nano-scale surface structures enhances energy transfer to solid targets and yields matter in extreme conditions. We report on the comparative study of laser-target interaction mechanisms with wire-structures of different size, revealing a transition from a coherent particle heating to a stochastic plasma heating regime which occurs when migrating from micro-scale to nano-scale wires. Experiments and kinetic simulations show that large gaps between the wires favour the generation of high-energy electrons via laser acceleration into the channels while gaps smaller than the amplitude of electron quivering in the laser field lead to less energetic electrons and multi-keV plasma generation, in agreement with previously published experiments. Plasma filling of nano-sized gaps due to picosecond pedestal typical of ultrashort pulses strongly affects the interaction with this class of targets reducing the laser penetration depth to approximately one hundred nanometers. The two heating regimes appear potentially suitable for laser-driven ion/electron acceleration schemes and warm dense matter investigation respectively.

12.
Rev Sci Instrum ; 87(8): 086103, 2016 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-27587174

RESUMO

The use of a gas cell as a target for laser wakefield acceleration (LWFA) offers the possibility to obtain stable and manageable laser-plasma interaction process, a mandatory condition for practical applications of this emerging technique, especially in multi-stage accelerators. In order to obtain full control of the gas particle number density in the interaction region, thus allowing for a long term stable and manageable LWFA, real-time monitoring is necessary. In fact, the ideal gas law cannot be used to estimate the particle density inside the flow cell based on the preset backing pressure and the room temperature because the gas flow depends on several factors like tubing, regulators, and valves in the gas supply system, as well as vacuum chamber volume and vacuum pump speed/throughput. Here, second-harmonic interferometry is applied to measure the particle number density inside a flow gas cell designed for LWFA. The results demonstrate that real-time monitoring is achieved and that using low backing pressure gas (<1 bar) and different cell orifice diameters (<2 mm) it is possible to finely tune the number density up to the 10(19) cm(-3) range well suited for LWFA.

13.
Rev Sci Instrum ; 87(2): 02A909, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26931970

RESUMO

An experimental campaign aiming at investigating the ion acceleration mechanisms through laser-matter interaction in femtosecond domain has been carried out at the Intense Laser Irradiation Laboratory facility with a laser intensity of up to 2 × 10(19) W/cm(2). A Thomson parabola spectrometer was used to obtain the spectra of the ions of the different species accelerated. Here, we show the energy spectra of light-ions and we discuss their dependence on structural characteristics of the target and the role of surface and target bulk in the acceleration process.

14.
Nat Commun ; 6: 8742, 2015 Nov 06.
Artigo em Inglês | MEDLINE | ID: mdl-26541650

RESUMO

Since the observation of the first brown dwarf in 1995, numerous studies have led to a better understanding of the structures of these objects. Here we present a method for studying material resistivity in warm dense plasmas in the laboratory, which we relate to the microphysics of brown dwarfs through viscosity and electron collisions. Here we use X-ray polarimetry to determine the resistivity of a sulphur-doped plastic target heated to Brown Dwarf conditions by an ultra-intense laser. The resistivity is determined by matching the plasma physics model to the atomic physics calculations of the measured large, positive, polarization. The inferred resistivity is larger than predicted using standard resistivity models, suggesting that these commonly used models will not adequately describe the resistivity of warm dense plasma related to the viscosity of brown dwarfs.

15.
Nat Commun ; 6: 6747, 2015 Apr 23.
Artigo em Inglês | MEDLINE | ID: mdl-25903920

RESUMO

Electron-positron pair plasmas represent a unique state of matter, whereby there exists an intrinsic and complete symmetry between negatively charged (matter) and positively charged (antimatter) particles. These plasmas play a fundamental role in the dynamics of ultra-massive astrophysical objects and are believed to be associated with the emission of ultra-bright gamma-ray bursts. Despite extensive theoretical modelling, our knowledge of this state of matter is still speculative, owing to the extreme difficulty in recreating neutral matter-antimatter plasmas in the laboratory. Here we show that, by using a compact laser-driven setup, ion-free electron-positron plasmas with unique characteristics can be produced. Their charge neutrality (same amount of matter and antimatter), high-density and small divergence finally open up the possibility of studying electron-positron plasmas in controlled laboratory experiments.

16.
Opt Express ; 22(5): 5375-86, 2014 Mar 10.
Artigo em Inglês | MEDLINE | ID: mdl-24663877

RESUMO

We present a study of Yb:YAG active media slabs, based on a ceramic layered structure with different doping levels. We developed a procedure allowing 3D numerical analysis of the slab optical properties as a consequence of the thermal load induced by the pump process. The simulations are compared with a set of experimental results in order to validate the procedure. These structured ceramics appear promising in appropriate geometrical configurations, and thus are intended to be applied in the construction of High Energy Diode Pumped Solid State Laser (DPSSL) systems working in high repetition-rate pulsed regimes.

17.
Clin Neurophysiol ; 125(8): 1663-8, 2014 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-24418221

RESUMO

OBJECTIVES: To apply a novel method to assess the characteristics of spinal movement in subjects with low back pain (LBP) in a functional task. METHODS: 17 subjects suffering from chronic non-specific LBP (average pain intensity: 1.8±1.6), and 17 age and gender matched controls performed a repetitive lifting task. Spinal movement was recorded using a novel sensor strip with 12 angle sensors recording the spinal dynamics in evenly spaced (25mm) locations along the spine. Recurrence quantification analysis was applied to different components of the angles to assess the structure of its variability. RESULTS: Mechanically, the LBP and control group performed the task similarly. Reported pain increased in the LBP group, yet task-related angular movement was not different. However, the percentage of determinism for the accessory angular movement (movement variability not directly related to task execution) was significantly higher for the LBP group, indicating a more deterministic (less random) structure of the muscle activation pattern variability. CONCLUSION: The structure of the variability of spinal movement differs in subjects with chronic non-specific LBP. SIGNIFICANCE: The determinism of accessory spinal movement may be a useful measure for evaluation of movement impairment in LBP and for monitoring rehabilitation effects.


Assuntos
Dor Crônica/fisiopatologia , Dor Crônica/reabilitação , Dor Lombar/fisiopatologia , Dor Lombar/reabilitação , Movimento/fisiologia , Coluna Vertebral/fisiopatologia , Análise e Desempenho de Tarefas , Adulto , Fenômenos Biomecânicos , Feminino , Análise de Fourier , Humanos , Remoção , Dor Lombar/classificação , Masculino , Pessoa de Meia-Idade , Medição da Dor , Recidiva , Inquéritos e Questionários
18.
Phys Rev Lett ; 111(18): 185001, 2013 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-24237527

RESUMO

The interaction of laser pulses with thin grating targets, having a periodic groove at the irradiated surface, is experimentally investigated. Ultrahigh contrast (~10(12)) pulses allow us to demonstrate an enhanced laser-target coupling for the first time in the relativistic regime of ultrahigh intensity >10(19) W/cm(2). A maximum increase by a factor of 2.5 of the cutoff energy of protons produced by target normal sheath acceleration is observed with respect to plane targets, around the incidence angle expected for the resonant excitation of surface waves. A significant enhancement is also observed for small angles of incidence, out of resonance.

19.
Artigo em Inglês | MEDLINE | ID: mdl-23496627

RESUMO

Spatially resolved K-shell spectroscopy is used here to investigate the interaction of an ultrashort laser pulse (λ=800 nm, τ=40 fs) with a Ti foil under intense irradiation (Iλ(2)=2×10(18)Wµm(2)cm(-2)) and the following fast electron generation and transport into the target. The effect of laser pulse polarization (p, s, and circular) on the Kα yield and line shape is probed. The radial structure of intensity and width of the lines, obtained by a discretized Abel deconvolution algorithm, suggests an annular distribution of both the hot electron propagation into the target and the target temperature. An accurate modeling of Kα line shapes was performed, revealing temperature gradients, going from a few eV up to 15-20 eV, depending on the pulse polarization. Results are discussed in terms of mechanisms of hot electron generation and of their transport through the preplasma in front of the target.


Assuntos
Lasers , Modelos Químicos , Gases em Plasma/química , Gases em Plasma/efeitos da radiação , Simulação por Computador , Raios X
20.
Phys Rev Lett ; 109(20): 205002, 2012 Nov 16.
Artigo em Inglês | MEDLINE | ID: mdl-23215496

RESUMO

The dynamics of magnetic fields with an amplitude of several tens of megagauss, generated at both sides of a solid target irradiated with a high-intensity (~10(19) W/cm(2)) picosecond laser pulse, has been spatially and temporally resolved using a proton imaging technique. The amplitude of the magnetic fields is sufficiently large to have a constraining effect on the radial expansion of the plasma sheath at the target surfaces. These results, supported by numerical simulations and simple analytical modeling, may have implications for ion acceleration driven by the plasma sheath at the rear side of the target as well as for the laboratory study of self-collimated high-energy plasma jets.

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