1.
J Org Chem
; 85(6): 4553-4559, 2020 03 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32133863
RESUMO
A tandem acetylene-activated SNAr-anionic cyclization strategy is presented for the synthesis of chalcogen-containing hetero[5]helicenes. Oxa-, thia-, and selena[5]helicenes are accessed from common ortho-fluoro-ethynylarene precursors, allowing the heteroatoms to be installed at the 1-position or 1- and 12-positions of the hetero[5]helicene inner core surface.