[Magnetic dipole interaction of endogenous magnetic nanoparticles with magnetoliposomes for targeted drug delivery].

Dynamics of magnetoliposomes binding to the tumor cells and the efficiency of their recognition for targeted drug delivery is largely determined by physical interaction. In this paper we assess the strength of magnetic dipole interaction that occurs between endogenous magnetic nanoparticles in tumor cells and exogenous magnetic nanoparticles as a component of magnetoliposomes, and compare it with the forces of specific binding of the antigen-antibody complex. To assess the strength of magnetic dipole interaction the model of chains of identical particles was used, and an order of magnitude, 9(-10) N, was obtained. Thus, the indicated force has an order of magnitude close to the forces of specific binding, and even more. The force of magnetic dipole interaction between a magnetically marked dosage form and tumor cells is virtually the additional specific binding force--"passive targeting" for targeted drug delivery in consequence of the fact that tumor cells tend to contain the number of biogenic nanoparticles of magnetite (Fe3O4) by an order of magnitude greater than normal.

[Intensification of extraction by yeast Saccharamyces cerevisiae 1968 of copper ions from a solution in magnetic field].

It was determined whether it is possible to intensify the biosorption of copper ions from a copper sulfate solution with yeast Saccharomyces cerevisiae 1968 by introducing a metal headpiece into the solution and by applying an external magnetic field. The study was carried out in a magnetic field oriented both parallel and perpendicular to the axes of the rods (with parallel and perpendicular geometry of the system) that make up the headpiece. It was shown that the extent of intensification of the extraction of copper ions at different geometries of the system differs insignificantly and that the extraction of copper ions from the solution occurs by biosorption and cementation onto the metal headpiece.