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1.
J Family Med Prim Care ; 10(10): 3664-3669, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34934663

RESUMO

BACKGROUND: Oral diseases can particularly have a harmful impact on the general health of individuals with certain systemic health problems or conditions. The aim of the study was to assess the oral health status and treatment needs among deaf, mute, and visually impaired children of the Gulbarga district. METHODOLOGY: A cross-sectional study was conducted among 284 deaf, mute, and visually impaired children of the Gulbarga district. A specially prepared structured questionnaire was used to record the demographic variables and oral hygiene practices. Type III clinical examination was carried out. Oral health status was assessed using the World Health Organization (WHO) assessment form (1997). Oral hygiene index-simplified (1964) was used to assess the oral hygiene status. RESULTS: A total of 284 children were examined, aged 6-24 years, with a mean age of 12.95 years (±3.13). The prevalence of dental caries was 49.3%, and 87.4% of the children suffered from periodontal disease. Oral hygiene status was poor in 24.7% of the children. CONCLUSION: The findings in the present study highlight the lack of dental treatment. There is a considerable need for the prevention and treatment of oral diseases among deaf, mute, and visually impaired children.

2.
J Pharm Bioallied Sci ; 13(Suppl 1): S598-S601, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-34447161

RESUMO

BACKGROUND: Psychiatric patients or mentally ill patients conform a substantial section of the community deserving special attention. This study aimed to assess the oral health status and treatment needs of psychiatric patients attending District Civil Hospital, Raichur, Karnataka. MATERIALS AND METHODS: The study group comprised 150 outpatients aged 18-64 years, attending the Department of Psychiatry, District Civil Hospital, Raichur. A specific questionnaire was drawn up and was used to record the demographic and medical data and oral hygiene practices. Type III clinical examination was carried out. The WHO Assessment Form 1997 was used to assess the oral health status of the study population. RESULTS: Of the 150 patients examined, 90 (60%) were male and 60 (40%) were female. The mean age of the patients was 33.79 ± 10.57 years. The majority (52%) were diagnosed with epilepsy and 18% had anxiety disorder. The prevalence of caries was 87.3%. Periodontal status, according to the Community Periodontal Index scores, was as follows: 54% of the patients had shallow pocket (4 mm-5 mm) and 32% of the patients had 6-mm or more deep pocket. CONCLUSION: This study highlights a substantial need for prevention and treatment of oral health needs among psychiatric patients, and to increase awareness toward oral health.

3.
Nepal J Epidemiol ; 6(4): 613-619, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-28804673

RESUMO

Oral cancer is one of the highly prevalent cancers worldwide and a leading cause of mortality in certain regions like South-Central Asia. It is a major public health problem. Late diagnosis, high mortality rates and morbidity are characteristics of the disease worldwide. For control of oral cancer an idea of the coverage of the same in the various regions is necessary. The estimated incidence, mortality and 5-year survival due to lip, oral cavity cancer in world is 3, 00, 373(2.1%), 1, 45, 328(1.8%) and 7, 02, 149(2.2%) respectively according to data of GLOBOCAN 2012. A changing trend in incidence and prevalence of oral cancer has been observed with more women and youngsters being affected by oral cancer.

4.
Gene ; 495(2): 199-204, 2012 Mar 10.
Artigo em Inglês | MEDLINE | ID: mdl-22245181

RESUMO

Down syndrome is a complex disorder characterized by well defined and distinctive phenotypic features. Approximately 2-3% of all live-born Down individuals are mosaics. Here we report a boy with suspected Down syndrome showing mosaicism for two different cell lines where one cell line is unexpected. The cytogenetic analysis by G-banding revealed a karyotype of 47 XY+21 [20]/46,X+marker [30]. Further, molecular cytogenetic analysis with spectral karyotyping identified the marker as a derivative of Y chromosome. The delineation of Y chromosomal DNA was done by quantitative real-time PCR and aneuploidy detection by quantitative fluorescence PCR. The Y-short tandem repeats typing was performed to estimate the variation in quantity as well as to find out the extent of deletion on Y chromosome using STR markers. Fluorescence in situ hybridization using Y centromeric probe was also performed to confirm the origin of the Y marker. Further fine mapping of the marker was carried out with three bacterial artificial chromosome clones RP11-20H21, RP11-375P13, RP11-71M14, which defined the hypothetical position of the deletion. In our study we defined the extent of deletion of the marker chromosome and also discussed it in relation with mosaicism. This is the first report of mosaic Down syndrome combined with a second de novo mosaic marker derived from the Y chromosome.


Assuntos
Cromossomos Humanos Y , Síndrome de Down/genética , Mosaicismo , Aneuploidia , Pré-Escolar , Cromossomos Artificiais Bacterianos , Análise Citogenética , Marcadores Genéticos , Humanos , Hibridização in Situ Fluorescente , Masculino , Reação em Cadeia da Polimerase em Tempo Real
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