Increased Metabolic Demand During Outside Walking in Darkness With No Vision or With Visual Aid.

INTRODUCTION: For tactical reasons, the foot-borne soldiers sometimes undertake nighttime operations. However, the metabolic demand during walking in complete darkness may be markedly increased. The purpose of this study was to investigate if metabolic demand and kinematics would change while walking on a gravel road and a slightly hilly trail in darkness with or without visual aid. MATERIALS AND METHODS: Fourteen cadets (11 men and 3 women, age: 25 ± 7 years, height: 178 ± 8 cm, and weight: 78 ± 13 kg) walked at 4 km/h on a straight gravel road and on a slightly hilly forest trail (n = 9). Both trials were performed at nighttime under four different conditions, wearing a headlamp (Light), blindfold (Dark), monocular (Mono), or binocular (Bino) night vision goggles. During the 10-minute walks, oxygen uptake, heart rate, and kinematic data were assessed. Ratings of perceived exertion, discomfort, and mental stress were evaluated after each condition using a category ratio scale. Physiologic and kinematic variables were evaluated using repeated-measures analysis of variance, whereas ratings were evaluated using non-parametric Friedman analysis of variance. RESULTS: Oxygen uptake was higher in all three conditions with no or limited vision (Dark, Mono, and Bino) than in the Light condition (P ≤ 0.02) when walking on both the gravel road (+5-8%) and the forest trail (+6-14%). Heart rate was higher during the Dark than during the Light condition when walking on the forest trail, whereas there was no difference between conditions on the gravel road. During both trials, gait frequency was higher during the Dark than during the Light, Mono, and Bino conditions. Ratings were generally low during all conditions. CONCLUSIONS: Walking on a gravel road or a forest trail wearing a blindfold or visual aid increased the metabolic demand. Thus, it appears that the metabolic demand is higher during overground walking with night vision goggles than with full vision, which may influence the performance of nighttime operations.

Metabolic Demands and Kinematics During Level Walking in Darkness With No Vision or With Visual Aid.

INTRODUCTION: Uniformed services commonly perform foot-borne operations at night, while using visual aid in terms of night vision goggles (NVG). During slow-level walking, complete lack of visual input alters kinematics and markedly increases the metabolic demand, whereas the effect on kinematics and energy expenditure of restricting the peripheral visual field by wearing NVG is still unknown. The purpose was to evaluate whether metabolic demands and kinematics during level walking are affected by complete darkness with and without visual aid. MATERIALS AND METHODS: Eleven healthy men walked on a treadmill (inclination: +2.3°, velocity: 4 km/h) with full vision in a lighted laboratory (Light), and in complete darkness wearing either a blindfold (Dark), or restricting the visual field to about 40° by wearing monocular (Mono) or binocular (Bino) NVG. Oxygen uptake ($\dot{\text{V}}$O2) was measured to evaluate metabolic demands. Inertial measurement units were used to estimate kinematics, and the outcome was validated by using a motion capture system. Ratings of perceived exertion, discomfort, and mental stress were evaluated after each condition using a Borg ratio scale. Physiologic and kinematic variables were evaluated using repeated measures analysis of variance (ANOVA), whereas ratings were evaluated using non-parametric Friedman ANOVA. RESULTS: $\dot{\text{V}}$ O2 was 20% higher in the Dark (1.2 ± 0.2 L/min) than the Light (1.0 ± 0.2 L/min) condition. Nominally, $\dot{\text{V}}$O2 in the Mono (1.1 ± 0.2 L/min) and Bino (1.1 ± 0.2 L/min) conditions fell in between those in the Light and Dark conditions but was not statistically different from either the Light or the Dark condition. Step length was shorter in the Dark (-9%, 1.22 ± 0.16 m) and Mono (-6%, 1.27 ± 0.09 m) conditions than in the Light condition (1.35 ± 0.11 m), whereas the Bino (1.28 ± 0.08 m) condition was not statistically different from either the Light or the Dark condition. The three conditions with no or limited vision were perceived more physically demanding, more uncomfortable, and more mentally stressful than the Light condition, and the Dark condition was perceived more mentally stressful than both NVG conditions. CONCLUSIONS: The study confirms that complete lack of visual cues markedly reduces the mechanical efficiency during level walking, even under obstacle-free and highly predictable conditions. That $\dot{\text{V}}$O2 and step length values for the NVG conditions fell in between those of the Light and Dark conditions suggest that both foveal and peripheral vision may play important roles in optimizing the mechanical efficiency during level walking.

Intra-Individual Test-Retest Variation Regarding Venous Gas Bubble Formation During High Altitude Exposures.

INTRODUCTION: Hypobaric decompression sickness remains a problem during high-altitude aviation. The prevalence of venous gas emboli (VGE) serves as a marker of decompression stress and has been used as a method in evaluating the safety/risk associated with aviation profiles and/or gas mixtures. However, information is lacking concerning the variability of VGE formation when exposed to the same hypobaric profile on different occasions. In this paper, intra-individual test-retest variation regarding bubble formation during repeated hypobaric exposures is presented. The data can be used to determine the sample size needed for statistical power.METHOD: A total of 19 male, nonsmoking subjects volunteered for altitude exposures to 24,000 ft (7315 m). VGE was measured using ultrasound scanning and scored according to the Eftedal-Brubakk (EB) scale. Intraindividual test-retest variation in bubble formation (maximum VGE) was evaluated in subjects exposed more than once to hypobaric pressure. The statistical reliability was examined between paired exposures using the Intraclass Correlation test. G*Power version 3.1.9.6 was used for power calculations.RESULTS: During repeated 20-30 and 70-min exposures to 24,000 ft, 42% (N = 19, CI 23-67%) and 29% (N = 7, CI 5-70%) of the subjects varied between maximum EB scores < 3 and ≥ 3. The sample size needed to properly reject statistical significance of 1 EB step nominal difference between two paired exposures varied between 29-51 subjects.CONCLUSION: The large intraindividual test-retest variations in bubble grades during repeated hypobaric exposures highlight the need for relatively large numbers of subjects to reach statistical power when there are no or small differences in decompression stress between the exposures.Ånell R, Grönkvist M, Eiken O, Elia A, Gennser M. Intra-individual test-retest variation regarding venous gas bubble formation during high altitude exposures. Aerosp Med Hum Perform. 2022; 93(1):46-49.

Inter- and Intra-Rater Level of Agreement in Ultrasonic Video Grading of Venous Gas Emboli.

INTRODUCTION: This study aimed to evaluate whether a short familiarization session is sufficient for individuals with no prior experience of sonography to both reliably and consistently evaluate the prevalence of venous gas emboli (VGE) from precordial ultrasonic videos.METHODS: A total of 10 adults with no prior experience of sonography were introduced to the Eftedal-Brubakk 6-grade scale and were shown 6 video sequences, each of a maximum of 10 heartbeats, representing each grading level. Thereafter, they independently evaluated the prevalence of VGE in 70 ultrasonic videos before and after a 14-d interval (test-retest; intra-rater), with these being compared to an experienced sonographer's grading (inter-rater).RESULTS: A significant inter-rater level of agreement was found between the naïve and experienced sonographers' bubble grading both during the first (W = 0.945) and second (W = 0.952) round of bubble evaluation. The naïve observers' evaluations were on average 79% (range: 61-95%) and 75% (range: 48-95%) in complete agreement with the experienced sonographer's gradings, while the level of agreement was 99% and 98% within 1 grade unit. There was a significant intra-rater level of agreement (κ = 0.845) during the test-retest series, with a mean percentage level of agreement of 87% (range: 72-93%).CONCLUSION: This study demonstrates that a short familiarization session enables individuals with no prior sonography experience to consistently evaluate VGE prevalence from precordial ultrasonic videos.Elia A, Ånell R, Eiken O, Grönkvist M, Gennser M. Inter- and intra-rater level of agreement in ultrasonic video grading of venous gas emboli. Aerosp Med Hum Perform. 2022; 93(1):54-57.

Cognitive performance, fatigue, emotional, and physiological strains in simulated long-duration flight missions.

Pilots in long-duration flight missions in single-seat aircraft may be affected by fatigue. This study determined associations between cognitive performance, emotions and physiological activation and deactivation - measured by heart rate variability (HRV) - in a simulated 11-h flight mission in the 39 Gripen aircraft. Twelve participants volunteered for the study. Perceived fatigue was measured by the Samn-Perelli Fatigue Index (SPFI). Cognitive performance was measured by non-executive and executive tasks. Emotions were assessed by the Circumplex Affect Space instrument. HRV was considered in relation to the cognitive tasks in four time points - Hours 3, 5, 7, 9 - and their associations with emotional ratings. Results indicated a decrease in performance in the non-executive task after approximately 7 h. This result was correlated with self-reported measures of fatigue. HRV, assessed by indices of parasympathetic modulation, remained unchanged for both non-executive and executive tasks over time (p > .05 for all). Significant correlations were observed between emotions and HRV; with increased boredom, increased passiveness, decreased stimulation, and decreased activeness, HRV indicators increased (p < .05). This suggests that a low self-regulatory effort for maintaining performance in these conditions was prevalent and that pilots could adapt to some degree to the demands and fatigue of long-duration missions.

Fatigue, Emotion, and Cognitive Performance in Simulated Long-Duration, Single-Piloted Flight Missions.

BACKGROUND: Fatigue of air force pilots has become an increasing concern due to changes in mission characteristics. In the current study we investigated fatigue, emotions, and cognitive performance in a simulated 11-h mission in the 39 Gripen fighter aircraft. METHODS: A total of 12 subjects were evaluated in a high-fidelity dynamic flight simulator for 12 consecutive hours. Perceived fatigue was measured by the Samn-Perelli Fatigue Index (SPFI). Emotions were assessed with the Circumplex Affect Space. Cognitive performance was assessed by five cognitive tasks. RESULTS: Significant increase in self-reported fatigue, general decrease in two positive emotional states, as well increase of one negative emotional state occurred after approximately 7 h into the mission. Self-reported fatigue negatively correlated with enthusiasm and cheerfulness (r 0.75; 0.49, respectively) and positively correlated with boredom and gloominess (r 0.61; r 0.30, respectively). Response time in the low-order task negatively correlated with enthusiasm, cheerfulness and calmness (r 0.44; r 0.41; r 0.37, respectively) and positively correlated with boredom and anxiousness (r 0.37; r 0.28, respectively). Mission duration had an adverse impact on emotions in these environmental conditions, particularly after 7 h. DISCUSSION: These results contribute to the understanding of fatigue development in general and of emotion-cognition relationships. These findings emphasize that both emotional states and the type of cognitive tasks to be performed should be considered for planning long-duration missions in single-piloted fighter aircrafts as to increase the probability of missions success. Rosa E, Gronkvist M, Kolegard R, Dahlstrom N, Knez I, Ljung R, Willander J. Fatigue, emotion, and cognitive performance in simulated long-duration, single-piloted flight missions. Aerosp Med Hum Perform. 2021; 92(9):710719.

High-altitude decompression strain can be reduced by an early excursion to moderate altitude while breathing oxygen.

Recent observations suggest that development of venous gas emboli (VGE) during high-altitude flying whilst breathing hyperoxic gas will be reduced by intermittent excursions to moderate altitude. The present study aimed to investigate if an early, single excursion from high to moderate altitude can be used as an in-flight means to reduce high-altitude decompression strain. Ten healthy men were investigated whilst breathing oxygen in a hypobaric chamber under two conditions, once during a 90-min continuous exposure to a simulated cabin altitude of 24,000 ft (High; H) and once during 10 min at 24,000 ft, followed by 30 min at 15,000 ft and by 80 min at 24,000 ft (high-low-high; H-L-H). VGE scores were assessed by cardiac ultrasound, using a 6-graded scale. In H, VGE increased throughout the course of the sojourn at 24,000 ft to attain peak value [median (range)] of 3 (2-4) at min 90, just prior to descent. In H-L-H, median VGE scores were 0 throughout the trial, except for at min 10, just prior to the excursion to 15,000 ft, whence the VGE score was 1.5 (0-3). Thus, an early, single excursion from high to moderate cabin altitude holds promise as an in-flight means to reduce the risk of altitude decompression sickness during long-duration high-altitude flying in aircraft with limited cabin pressurization. Presumably, such excursion acts by facilitating the gas exchange in decompression bubbles from a predomination of nitrogen to that of oxygen.

Whole-body vibration preconditioning reduces the formation and delays the manifestation of high-altitude-induced venous gas emboli.

NEW FINDINGS: What is the central question of this study? Is performing a 30-min whole-body vibration (WBV) prior to a continuous 90-min exposure at 24,000 ft sufficient to prevent venous gas emboli (VGE) formation? What is the main finding and its importance? WBV preconditioning significantly reduces the formation and delays the manifestation of high-altitude-induced VGE. This study suggests that WBV is an effective strategy in lowering decompression stress. ABSTRACT: Rapid decompression may give rise to formation of venous gas emboli (VGE) and resultantly, increase the risk of sustaining decompression sickness. Preconditioning aims at lowering the prevalence of VGE during decompression. The purpose of this study was to investigate the efficacy of whole-body vibration (WBV) preconditioning on high-altitude-induced VGE. Eight male subjects performed, on separate days in a randomised order, three preconditioning strategies: 40-min seated-rest (control), 30-min seated-rest followed by 150 knee-squats performed over a 10-min period (exercise) and 30-min WBV proceeded by a 10-min seated-rest. Thereafter, subjects were exposed to an altitude of 24,000 ft (7315 m) for 90 min whilst laying in a supine position and breathing 100% oxygen. VGE were assessed ultrasonically both during supine rest (5-min intervals) and after three fast, unloaded knee-bends (15-min intervals) and were scored using a 5-grade scale and evaluated using the Kisman Integrated Severity Score (KISS). There was a significant difference in VGE grade (P < 0.001), time to VGE manifestation (P = 0.014) and KISS score following knee-bends (P = 0.002) across protocols, with a trend in KISS score during supine rest (P = 0.070). WBV resulted in lower VGE grades (median (range), 1 (0-3)) and KISS score (2.69 ± 4.56 a.u.) compared with control (2 (1-3), P = 0.002; 12.86 ± 8.40 a.u., P = 0.011) and exercise (3 (2-4) , P < 0.001; 22.04 ± 13.45 a.u., P = 0.002). VGE were detected earlier during control (15 ± 14 min, P = 0.024) and exercise (17 ± 24 min, P = 0.032) than WBV (54 ± 38 min). Performing a 30-min WBV prior to a 90-min continuous exposure at 24,000 ft both delays the manifestation and reduces the formation of VGE compared with control and exercise preconditioning.

Hyperoxic Effects on Decompression Strain During Alternating High and Moderate Altitude Exposures.

INTRODUCTION: In fighter aircraft, long-duration high-altitude sorties are typically interrupted by refueling excursions to lower altitude. In normoxia, excursions to moderate cabin altitude may increase the occurrence of venous gas emboli (VGE) at high cabin altitude. The aim was to investigate the effect of hyperoxia on VGE and decompression sickness (DCS) during alternating high and moderate altitude exposure.METHODS: In an altitude chamber, 13 healthy men were exposed to three different conditions: A) 90 min at 24,000 ft (7315 m) breathing normoxic gas (54% O2; H-NOR); B) 90 min at 24,000 ft breathing hyperoxic gas (90% O2; H-HYP); and C) three 30-min exposures to 24,000 ft interspersed by two 30-min exposures to 18,000 ft (5486 m) breathing 90% O2 (ALT-HYP). VGE occurrence was evaluated from cardiac ultrasound imaging. DCS symptoms were rated using a scale.RESULTS: DCS occurred in all conditions and altogether in 6 of the 39 exposures. The prevalence of VGE was similar in H-NOR and H-HYP throughout the exposures. During the initial 30 min at 24,000 ft, the prevalence of VGE was similar in ALT-HYP as in the other two conditions, whereas, after the first excursion to 18,000 ft, the VGE score was lower in ALT-HYP than in H-NOR and H-HYP.DISCUSSION: Hyperoxic excursions from 24,000 to 18,000 ft reduces VGE occurrence, presumably by facilitating diffusive gas exchange across the bubble surfaces, increasing the share of bubble content contributed by oxygen. Still, the excursions did not abolish the DCS risk.Ånell R, Grönkvist M, Gennser M, Eiken O. Hyperoxic effects on decompression strain during alternating high and moderate altitude exposures. Aerosp Med Hum Perform. 2021; 92(4):223230.

Heat Strain with Two Different Ventilation Vests During a Simulated 3-Hour Helicopter Desert Mission.

BACKGROUND: The study investigated the heat strain of personnel operating in the rear cabin of a helicopter during desert-climate missions, and to what extent the strain can be mitigated by use of battery-driven ventilation vests.METHODS: Eight men undertook 3-h simulated flight missions in desert conditions (45C, 10% humidity, solar radiation). Each subject participated in three conditions wearing helicopter flight equipment, including body armor, and either: a ventilation vest with a 3-dimensional mesh (Vent-1), a ventilation vest with a foam sheet incorporating channels to direct the air flow (Vent-2), or a T-shirt (NoVent); each mission comprised a 10-min walk, followed by sitting for 30 min, kneeling on a vibration platform for 2 h, and finally 30 min of sitting. Core temperature, heart rate, skin temperatures and heat flux, oxygen uptake, sweating rate, and subjective ratings were recorded. Evaporative capacity and thermal resistance of the garments were determined using a thermal manikin.RESULTS: All subjects completed the NoVent and Vent-1 conditions, whereas in the Vent-2 condition, one subject finished prematurely due to heat exhaustion. The increase in core temperature was significantly (P 0.01) greater in Novent (0.93C) and Vent-2 (0.88C) than in Vent-1 (0.61C). Evaporative capacity was significantly higher for Vent-1 (7.8 g min1) than for NoVent (4.1 g min1) and Vent-2 (4.4 g min1).DISCUSSION: Helicopter personnel may be at risk of heat exhaustion during desert missions. The risk can be reduced by use of a ventilation vest. However, the cooling efficacy of ventilation vests differs substantially depending on their design and ventilation concept.Grönkvist M, Mekjavic I, Ciuha U, Eiken O. Heat strain with two different ventilation vests during a simulated 3-hour helicopter desert mission. Aerosp Med Hum Perform. 2021; 92(4):248256.

Evolution and Preservation of Venous Gas Emboli at Alternating High and Moderate Altitude Exposures.

INTRODUCTION: The evolution and preservation of venous gas emboli (VGE), as markers of decompression stress, were investigated during alternating high- and moderate altitude exposures, thus, simulating a fighter aircraft high-altitude flight, interrupted by refueling excursions to lower altitudes.METHODS: Eight men served as subjects during three normoxic simulated altitude exposures: High = 90 min at 24,000 ft; High-Low = three × 30 min at 24,000 ft, interspersed by two 30-min intervals at 15,000 ft; Low = 90 min at 15,000 ft. VGE scores were assessed by cardiac ultrasound, using a 5-grade scale. Respiratory nitrogen exchange was measured continuously using a modified closed-circuit electronic rebreather.RESULTS: Both High and High-Low induced persistent VGE, with no inter-condition difference either at rest [median (range): High: 1 (0-3), High-Low: 2 (0-3)] or during unloaded knee-bends [High: 3 (1-4), High-Low: 3 (0-4)], whereas VGE was considerably less in Low, both at rest [0 (0-1)] and during knee-bends [0 (0-2)]. In High-Low, VGE decreased temporarily during the 15,000-ft excursions, but resumed pre-excursion values upon return to 24,000 ft. During the final descent to ground level, VGE were more persistent following High-Low than High. In both High and Low, nitrogen was continuously washed out at altitude, whereas in High-Low, the washout at 24,000 ft was interrupted by nitrogen uptake at 15,000 ft.DISCUSSION: In normoxic conditions, long-duration flying at a cabin altitude of 24,000 ft is associated with substantial VGE occurrence, which is not abolished by intermittent excursions to a cabin altitude of 15,000 ft.Ånell R, Grönkvist M, Gennser M, Eiken O. Evolution and preservation of venous gas emboli at alternating high and moderate altitude exposures. Aerosp Med Hum Perform. 2020; 91(1):11-17.

Nitrogen Washout and Venous Gas Emboli During Sustained vs. Discontinuous High-Altitude Exposures.

INTRODUCTION: The frequency of long-duration, high-altitude missions with fighter aircraft is increasing, which may increase the incidence of decompression sickness (DCS). The aim of the present study was to compare decompression stress during simulated sustained high-altitude flying vs. high-altitude flying interrupted by periods of moderate or marked cabin pressure increase.METHODS: The level of venous gas emboli (VGE) was assessed from cardiac ultrasound images using the 5-degree Eftedal-Brubakk scale. Nitrogen washout/uptake was measured using a closed-circuit rebreather. Eight men were investigated in three conditions: one 80-min continuous exposure to a simulated cabin altitude of A) 24,000 ft, or four 20-min exposures to 24,000 ft interspersed by three 20-min intervals at B) 20,000 ft or C) 900 ft.RESULTS: A and B induced marked and persistent VGE, with peak bubble scores of [median (range)]: A: 2.5 (1-3); B: 3.5 (2-4). Peak VGE score was less in C [1.0 (1-2), P < 0.01]. Condition A exhibited an initially high and exponentially decaying rate of nitrogen washout. In C the washout rate was similar in each period at 24,000 ft, and the nitrogen uptake rate was similar during each 900-ft exposure. B exhibited nitrogen washout during each period at 24,000 ft and the initial period at 20,000 ft, but on average no washout or uptake during the last period at 20,000 ft.DISCUSSION: Intermittent reductions of cabin altitude from 24,000 to 20,000 ft do not appear to alleviate the DCS risk, presumably because the pressure increase is not sufficient to eliminate VGE. The nitrogen washout/uptake rate did not reflect DCS risk in the present exposures.Ånell R, Grönkvist M, Eiken O, Gennser M. Nitrogen washout and venous gas emboli during sustained vs. discontinuous high-altitude exposures. Aerosp Med Hum Perform. 2019; 90(6):524-530.

G Tolerance During Open- vs. Closed-Loop G-Time Control.

BACKGROUND: +Gz tolerance is traditionally determined in centrifuges with open-loop G control, i.e., the centrifuge is under operator control (open loop), and thus the test subject is unable to influence the Gz load. In modern centrifuges, however, the subject is commonly able to continuously control the Gz load (closed loop). It is a widespread opinion among fighter pilots that +Gz tolerance is higher under closed- than open-loop G control. The aims were to investigate whether +Gz tolerance is higher in closed- than open-loop G control, and whether it is possible to use closed-loop G control during precise determination of +Gz tolerance. METHODS: Relaxed +Gz tolerance was determined in eight men during rapid Gz-onset rate (ROR) under three conditions: 1) OL-VFB, open loop with visual feedback; 2) OL-NFB, open loop with no visual feedback; and 3) CL, closed loop. Straining +Gz tolerance was determined in 10 men during ROR in OL and CL conditions. RESULTS: Relaxed +Gz tolerance did not differ between CL (3.66 Gz), OL-VFB (3.70 Gz) and OL-NFB (3.64 Gz). Straining +Gz tolerance was similar in the CL (8.5 Gz) and OL (8.6 Gz) conditions. In the CL condition, the Gz load varied substantially and was on average lower than in the OL conditions, at any stipulated G-time profile. DISCUSSION: There is no systematic difference in relaxed or straining +Gz tolerance as determined in closed- vs. open-loop G-controlled systems. During closed-loop control, precision and reproducibility are too low to recommend it for accurate determination of relaxed G tolerance.Grönkvist M, Levin B, Eiken O. G tolerance during open- vs. closed-loop G-time control. Aerosp Med Hum Perform. 2018; 89(9):798-804.

The Effect of Low Ambient Relative Humidity on Physical Performance and Perceptual Responses during Load Carriage.

Introduction: The study evaluated the effect of low ambient relative humidity on physical performance and perceptual responses during load carriage in a hot environment. Methods: Ten heat-unacclimatized male subjects participated in three 130-min trials, during which they walked on a treadmill, carrying a load of ~35 kg, at a speed of 3.2 km.h-1, with an incident wind at the same velocity and ambient temperature at 45°C. Each trial commenced with a 10-min baseline at 20°C and 50% relative humidity (RH), the subjects transferred to a climatic chamber and commenced their simulated hike, comprising two 50-min walks separated by a 20-min rest period. In two, full protective equipment (FP) trials, RH was 10% (partial pressure of water vapor, p H2O = 7.2 mmHg) in one (FP10), and 20% (p H2O = 14.4 mmHg; FP20) in the other. In the control trial, subjects were semi-nude (SN) and carried the equipment in their backpacks; RH was 20%. Measurements included oxygen uptake, ventilation, heart rate, rectal and skin temperatures, heat flux, temperature perception, and thermal comfort. Results: In FP20, four subjects terminated the trial prematurely due to signs of heat exhaustion; there were no such signs in FP10 or SN. Upon completion of the trials, pulmonary ventilation, heart rate, and rectal temperature were lower in FP10 (33 ± 5 l/min; 128 ± 21 bpm; 38.2 ± 0.4°C) and SN (34 ± 4 l/min; 113 ± 18 bpm; 38.1 ± 0.4°C than in FP20 (39 ± 8 l/min; 145 ± 12 bpm; 38.6 ± 0.4°C). Evaporation was significantly greater in the SN compared to FP10 and FP20 trials. FP10 was rated thermally more comfortable than FP20. Conclusion: A lower ambient partial pressure of water vapor, reflected in a lower ambient relative humidity, improved cardiorespiratory, thermoregulatory, and perceptual responses during load carriage.

Intraocular pressure and cerebral oxygenation during prolonged headward acceleration.

PURPOSE: Supra-tolerance head-to-foot directed gravitoinertial load (+Gz) typically induces a sequence of symptoms/signs, including loss of: peripheral vision-central vision-consciousness. The risk of unconsciousness is greater when anti-G-garment failure occurs after prolonged rather than brief exposures, presumably because, in the former condition, mental signs are not consistently preceded by impaired vision. The aims were to investigate if prolonged exposure to moderately elevated +Gz reduces intraocular pressure (IOP; i.e., improves provisions for retinal perfusion), or the cerebral anoxia reserve. METHODS: Subjects were exposed to 4-min +Gz plateaux either at 2 and 3 G (n = 10), or at 4 and 5 G (n = 12). Measurements included eye-level mean arterial pressure (MAP), oxygenation of the cerebral frontal cortex, and at 2 and 3 G, IOP. RESULTS: IOP was similar at 1 (14.1 ± 1.6 mmHg), 2 (14.0 ± 1.6 mmHg), and 3 G (14.0 ± 1.6 mmHg). During the G exposures, MAP exhibited an initial prompt drop followed by a partial recovery, end-exposure values being reduced by ≤30 mmHg. Cerebral oxygenation showed a similar initial drop, but without recovery, and was followed by either a plateau or a further slight decrement to a minimum of about -14 µM. CONCLUSION: Gz loading did not affect IOP. That cerebral oxygenation remained suppressed throughout these G exposures, despite a concomitant partial recovery of MAP, suggests that the increased risk of unconsciousness upon G-garment failure after prolonged +Gz exposure is due to reduced cerebral anoxia reserve.

Strategies for increasing evaporative cooling during simulated desert patrol mission.

The study evaluated the efficiency of two heat dissipation strategies under simulated desert patrol missions. Ten men participated in four trials, during which they walked on a treadmill (45 °C, 20% relative humidity), carrying a load of 35 kg; two 50-min walks were separated by a 20-min rest. Cooling strategies, provided by an ambient air-ventilated vest (active cooling condition, AC), or water spraying of the skin during the rest (passive cooling condition, PC), in addition to reduced clothing and open zippers, were compared to conditions with full protective (FP) clothing and naked condition (NC). Skin temperature was higher during NC (37.9 ± 0.4 °C; p < 0.001), and rectal temperature and heart rate were higher during FP (38.6 ± 0.4 °C, p < 0.001 and 145 ± 12, p < 0.001, respectively), compared to other conditions. Four subjects terminated the trial prematurely due to signs of heat exhaustion in FP. Both cooling strategies substantially improved evaporative cooling. PRACTITIONER SUMMARY: Cooling strategies, provided by an ambient air-ventilated vest and water spraying of the skin, were compared to conditions with full protective clothing and a naked condition during a simulated desert patrol mission. Both cooling strategies improved evaporative cooling and reduced heat strain, compared to the full protection condition.

Signs and symptoms during supra-tolerance +G(z) exposures, with reference to G-garment failure.

INTRODUCTION: +G(z) exposure above the tolerance threshold typically induces a sequence of symptoms/signs, with loss of: peripheral vision, central vision (black out), and consciousness (G-LOC). The aims of this study were to investigate: 1) whether G history influences latent time to, or sequence of, symptoms/signs upon G exposures exceeding the tolerance threshold; and 2) how pilots respond to a sudden loss of pressure in the anti-G garment (AGG) in flight-like scenarios. METHODS: There were 14 subjects who were exposed to rapid onset rate +G(z)-time profiles, with plateaus 1 and 2 G above the relaxed tolerance level, without initial pressurization of the AGG (NoAGG) and when losing AGG pressure after 10 (AGG_10) and 120 (AGG_120) s at the plateau. Simulated target-chase flights during which AGG pressure was released were performed by seven pilots; the pilot was instructed to behave as during real flight. RESULTS: Latent time to symptoms was shorter at +2 G than at +1 G, and shorter in AGG_10 and AGG_120 than in NoAGG. In AGG_120, 43 and 64% of the subjects experienced serious symptoms (black out, Almost LOC, G-LOC) at +1 and +2 G, respectively, compared to 21 and 54% in AGG 10 and 7 and 29% in NoAGG. The incidence of A-LOC/ G-LOC was higher in AGG_10 and especially in AGG_120 than in NoAGG. During the target chase, one pilot did not notice the pressure loss, one experienced G-LOC, and two A-LOC. DISCUSSION: The risk of serious consequences of G exposure exceeding the tolerance level appears to be greater when G-garment failure occurs after a prolonged than after a brief exposure.

G-protection mechanisms afforded by the anti-G suit abdominal bladder with and without pressure breathing.

BACKGROUND: G protection afforded by the abdominal bladder of a pneumatic anti-G suit is usually attributed to counteraction of G-induced caudad displacement of the heart and pooling of blood in the abdominal veins. The study examined whether the abdominal bladder might provide G protection also via other mechanisms. METHODS: Each subject was exposed to +Gz loads while sitting relaxed, wearing a full-coverage anti-G suit modified to permit separate pressurization of the abdominal and leg bladders. In two experimental series (N = 8, N = 14), subjects were breathing at positive airway pressure (PPB); in a third series, five subjects were breathing at atmospheric airway pressure. Intrathoracic pressures were estimated by use of esophageal catheters. RESULTS: During PPB at high G loads, intrathoracic pressure was higher with than without the pressurized abdominal bladder. In 7 of the 14 subjects, basilar intrathoracic pressure exceeded airway pressure during PPB when the abdominal bladder was pressurized. The mean arterial pressure response at high G loads was higher in this subset of subjects (55 +/- 23 mmHg) than in the subjects in whom airway pressure exceeded intrathoracic pressure (41 +/- 27 mmHg). Without PPB at increased G load, the intrathoracic pressure gradient was higher with than without the pressurized abdominal bladder. DISCUSSION: During PPB, the abdominal bladder acts as an airway counterpressure, thereby facilitating pressure transmission from the airways to the thorax and hence improving G protection. It also appears that in several individuals, pressure may be transmitted from the abdominal bladder to the thorax and heart.

The perception of roll tilt in pilots during a simulated coordinated turn in a gondola centrifuge.

BACKGROUND: It has previously been reported that nonpilots underestimate the roll tilt angle after acceleration in a gondola centrifuge. The aim of the present work was to elucidate the significance of flight experience for roll tilt perception based on vestibular information. METHODS: The subjective visual horizontal (SVH) was measured by means of an adjustable luminous line in darkness. Eight nonpilots (N), nine fighter pilots (F), and eight helicopter pilots (H) underwent two centrifuge runs (2 G, 5 min) heading forward and backward, respectively. The roll position of the gondola (60 degrees at 2 G) was controlled so that the subject was always upright with respect to the gravitoinertial force. RESULTS: Upon acceleration of the centrifuge there was a tilt of the SVH in a direction compensatory to the inclination of the gondola. This tilt was larger in the forward position [N: 17.2 +/- 6.4 degrees, F: 31.2 +/- 16.4 degrees, H: 33.6 +/- 18.2 degrees (means +/- SD)] than in the backward position (N: -5.0 +/- 6.8 degrees, F: -12.2 +/- 17.4 degrees, H: -10.4 +/- 15.4 degrees). In N the tilt declined with time, approaching zero by the end of the 2-G plateau. In the pilots it was significantly larger and did not decline. CONCLUSION: Flight experience results in an increased ability to perceive the roll tilt during movement along a curved path. That this can be revealed in a centrifuge might suggest that acceleration of the centrifuge constitutes a movement pattern which is similar, from a vestibular point of view, to that of an airplane entering a coordinated turn.