RESUMO
Human rabies encephalitis is rare in Canada, with only five cases reported in the past 30 years. The first and only patient who contracted rabies encephalitis in British Columbia died in 2003. Here we provide the first detailed clinical and pathological description of that case, which had several unusual features, including preexisting immunosuppression, paralytic presentation, prolonged survival, focal lesions on neuroimaging and severe neuropathology with focal necrosis, intense inflammation, and abundant viral inclusion bodies.
Assuntos
Encefalite Viral/diagnóstico por imagem , Raiva/virologia , Lobo Frontal/diagnóstico por imagem , Lobo Frontal/virologia , Humanos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-IdadeRESUMO
OBJECTIVE: The educational objectives for this self-assessment module are for the participant to exercise, self-assess, and improve his or her understanding of evaluation of scoliosis using radiography. CONCLUSION: The solutions to the questions in this activity review the imaging characteristics of radiologic evaluation of scoliosis.
Assuntos
Escoliose/diagnóstico por imagem , Adolescente , Criança , Humanos , Imageamento por Ressonância Magnética , Equilíbrio Postural , Intensificação de Imagem Radiográfica , Escoliose/etiologia , Escoliose/fisiopatologiaAssuntos
Escoliose/diagnóstico por imagem , Adolescente , Pesos e Medidas Corporais , Humanos , Imageamento por Ressonância Magnética , Equilíbrio Postural , Intensificação de Imagem Radiográfica , Reprodutibilidade dos Testes , Escoliose/patologia , Escoliose/cirurgia , Índice de Gravidade de DoençaRESUMO
PURPOSE: To determine the prevalence of carotid artery stenosis in patients who have received ipsilateral head-and-neck radiotherapy and have no symptoms of cerebrovascular disease. METHODS AND MATERIALS: Forty patients underwent ultrasound and computed tomography angiography of their carotid arteries. The vessels on the irradiated side were compared with those on the unirradiated side in a matched-pair analysis with regard to any stenosis, stenosis > or =60% in the internal carotid artery/carotid bulb, intima medial thickness (IMT), and grade of wall abnormalities. History, physical, and fasting blood levels were taken to detect risk factors for carotid disease. RESULTS: Fourteen irradiated carotid trees bore one or more stenosis vs. five in the unirradiated ones (p = 0.03). There were six bulb/internal carotid artery stenoses > or =60% in the irradiated carotids vs. one in the unirradiated (OR 6:1, p = 0.13). IMT and grade of vessel wall abnormality were higher in the irradiated carotids, but only at doses > or =50 Gy, and only at measurement points that lay within the radiation portals. CONCLUSION: Radiation appears to cause carotid artery stenosis. There may be a dose threshold for carotid wall changes, which has relevance for radiotherapy in several tumor sites.