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Sex Transm Infect ; 91(1): 11-3, 2015 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-25096921

RESUMO

OBJECTIVES: To describe antibiotic use for treatment of Mycoplasma genitalium (MG) at an urban sexual health centre in Australia. To describe MG positivity rates in those returning for 1 month test of cure (TOC) following first-line antibiotic treatment for MG. METHODS: Retrospective cross-sectional case-note review for all patients diagnosed with MG at Sydney Sexual Health Centre from 2009 to 2013. RESULTS: Two hundred and eighteen MG cases were identified; 66% were male and 90% were symptomatic at presentation. Four people did not return for treatment. Azithromycin containing regimens were prescribed as first-line treatment in 88% of cases; azithromycin 1 g stat in 75% of cases and a course of extended azithromycin 1 g stat plus 500 mg daily for 4 days in 14% of cases. TOC was performed in 53% (95% CI 46% to 60%) of cases and 28% (95% CI 20% to 38%) of these cases were MG-positive at TOC. Of those having a MG-positive result at TOC, 26% received azithromycin 1 g stat and 33% received extended azithromycin. Accounting for cases lost to follow-up in azithromycin containing regimens, the positive MG TOC rate was estimated to be between 15% and 61%. CONCLUSIONS: High rates of MG positivity were found in those attending TOC following first-line treatment of MG with azithromycin containing regimens.


Assuntos
Antibacterianos/uso terapêutico , Doenças Urogenitais Femininas/tratamento farmacológico , Doenças Urogenitais Masculinas/tratamento farmacológico , Infecções por Mycoplasma/tratamento farmacológico , Mycoplasma genitalium/isolamento & purificação , Infecções Sexualmente Transmissíveis/tratamento farmacológico , Adolescente , Adulto , Austrália , Azitromicina/uso terapêutico , Estudos de Coortes , Estudos Transversais , Feminino , Doenças Urogenitais Femininas/diagnóstico , Doenças Urogenitais Femininas/microbiologia , Humanos , Masculino , Doenças Urogenitais Masculinas/diagnóstico , Doenças Urogenitais Masculinas/microbiologia , Pessoa de Meia-Idade , Infecções por Mycoplasma/diagnóstico , Infecções por Mycoplasma/microbiologia , Estudos Retrospectivos , Infecções Sexualmente Transmissíveis/diagnóstico , Infecções Sexualmente Transmissíveis/microbiologia , Resultado do Tratamento , Adulto Jovem
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