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1.
Neurol India ; 70(1): 31-36, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35263850

RESUMO

Meningiomas are benign intracranial neoplasms arising from arachnoid cap cells. High grade meningiomas are uncommon and metastasis from these is an extremely rare event. Commonest sites of metastasis from high grade meningiomas include lung, liver, lymph nodes and bone. It is unusual for meningiomas to recur in the surgical track following excision. More so, it is even the rarest phenomenon for a meningioma to implant in subgaleal location. Various mechanisms have been proposed for the scalp implantation vis-à-vis CSF dissemination, direct surgical implantation etc., It may apply to all histological grades of meningiomas. Even the benign tumors have been shown to seed at postoperative scar. This seems to have provoked our interest to review the literature regarding this scalp implantation. We have reviewed all the cases where surgical excision of intracranial meningiomas has led to seeding of surgical track as well as scalp. We have discussed the various genetic aberrations that can guide us regarding the progression of the tumor and prognosis. We also report a case of surgical track and scalp implantation of an atypical intraventricular meningioma following excision.


Assuntos
Neoplasias Meníngeas , Meningioma , Humanos , Neoplasias Meníngeas/patologia , Neoplasias Meníngeas/cirurgia , Meningioma/patologia , Meningioma/cirurgia , Recidiva Local de Neoplasia/cirurgia , Prognóstico , Couro Cabeludo/cirurgia
2.
Indian J Exp Biol ; 50(1): 56-60, 2012 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-22279942

RESUMO

Wound healing activity of methanol extract of Alternanthera brasiliana [5% (w/w) ointment] was evaluated in experimental burn wound model in rats. Healing potential was assessed by the rate of wound contraction, estimation of anti-oxidants like catalase, superoxide dismutase, reduced glutathione, protein, vitamin C and hydroxyproline, along with histopathological examination on 8th day post wounding. The statistical data indicated that there was significant increase in wound contraction along with augmented level of antioxidants in granulation tissues in A. brasiliana treated group. Histopathological assessment of the granulation tissue revealed formation of epidermis with keratin layer and deposition of collagen fibers after treatment with the plant extract.


Assuntos
Amaranthaceae/química , Queimaduras/tratamento farmacológico , Derme/efeitos dos fármacos , Fitoterapia , Extratos Vegetais/uso terapêutico , Cicatrização/efeitos dos fármacos , Administração Cutânea , Animais , Antioxidantes/metabolismo , Queimaduras/metabolismo , Catalase/metabolismo , Derme/citologia , Feminino , Tecido de Granulação/efeitos dos fármacos , Masculino , Pomadas/uso terapêutico , Ratos , Ratos Sprague-Dawley , Higiene da Pele
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