Posterior Segment Involvement in Childhood Presumed Trematode Induced Granulomatous Anterior Uveitis.

PURPOSE: To outline posterior segment characteristics of presumed-trematode induced granulomatous uveitis. DESIGN: A cross-sectional case series. METHODS: The study included 56 patients (60 eyes) presented with anterior chamber (AC) granulomas. Involvement of the posterior segment structures has been documented and reported. RESULTS: The mean age of the patients was 11.8 years (range 6-14 years). Posterior segment findings were vitritis in 9 eyes (15%), optic disc granuloma in 2 eyes (3.3%), optic disc hyperaemia in one eye (1.7%), macular oedema in 2 eyes (3.3%), epiretinal membrane in 3 eyes (5%), retinal vasculitis in one eye, a peripheral focus of retinitis in one eye (1.7%), and choroid thickening in 10 eyes (6.7%), with localised choroidal granuloma in one eye (1.7%). CONCLUSION: Presumed trematode-induced anterior chamber (AC) granuloma is not only restricted to the anterior segment of the eye, but posterior segment associations that may threaten vision should also be considered.

Assessment of Corneal Densitometry in Big-Bubble Dissection Versus Manual Dissection Deep Anterior Lamellar Keratoplasty.

PURPOSE: The aim of this study was to assess corneal densitometry and visual outcomes after big-bubble deep anterior lamellar keratoplasty (BB-DALK) and manual dissection deep anterior lamellar keratoplasty in patients with keratoconus. METHODS: This retrospective comparative observational study included 40 keratoconic patients who underwent DALK surgery: 22 eyes had BB-DALK (group I) and 18 eyes had failed BB technique and DALK was completed by manual dissection (group II). Best -corrected visual acuity (BCVA), corneal topographic parameters, residual stromal tissue thickness, and endothelial cell count were recorded at 1, 3, 6, and 12 months postoperatively. Densitometric analysis of different corneal layers and zones was performed using Scheimpflug tomography at each visit; values were recorded and compared between the 2 groups. RESULTS: At 1 and 6 months postoperatively, BCVA was better in group I than in group II, but with no statistically significant difference. At 12 months, the visual acuities became nearly similar in both groups (0.30 ± 0.13 vs. 0.30 ± 0.14 logarithm of the minimum angle of resolution, P = 0.888). Regarding corneal densitometric analysis, the recorded values for the posterior corneal layer were significantly higher in group II compared with group I at 3, 6, 9, and 12 months postoperatively in the 0- to 2-mm zone (P < 0.001) and the 2- to 6-mm zone (P = 0.029, 0.028, 0.001, and <0.001). CONCLUSIONS: Manual dissection DALK after failed BB technique may affect the interface stromal reflectivity up to 12 months postoperatively. However, this does not significantly affect the visual acuity in comparison with successful BB-DALK.