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IEEE/ACM Trans Comput Biol Bioinform ; 17(6): 1895-1906, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-30869629

RESUMO

We present an analysis of the problem of identifying biological context and associating it with biochemical events described in biomedical texts. This constitutes a non-trivial, inter-sentential relation extraction task. We focus on biological context as descriptions of the species, tissue type, and cell type that are associated with biochemical events. We present a new corpus of open access biomedical texts that have been annotated by biology subject matter experts to highlight context-event relations. Using this corpus, we evaluate several classifiers for context-event association along with a detailed analysis of the impact of a variety of linguistic features on classifier performance. We find that gradient tree boosting performs by far the best, achieving an F1 of 0.865 in a cross-validation study.


Assuntos
Biologia Computacional/métodos , Mineração de Dados/métodos , Processamento de Linguagem Natural , Animais , Pesquisa Biomédica , Bases de Dados Factuais , Humanos , Camundongos
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