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1.
Nutrients ; 12(2)2020 Jan 30.
Artigo em Inglês | MEDLINE | ID: mdl-32019156

RESUMO

Pregnancy is a stage in a woman's life when she is more open to receiving health advice, especially related to diet. However, women are often caught between receiving scientifically unfounded myths and concrete empirical knowledge. Culturally perpetuated myths may be acted upon more than knowledge, but research on these concepts, especially in the Americas, is scarce. This cross-sectional study aimed to describe the frequency of diet and nutrition myths and knowledge and describe the associated factors in pregnant mothers receiving care in Mexico City. A total of 695 pregnant adults and 322 pregnant adolescents participated in this study, in which they responded to a questionnaire on nutrition and diet myths, knowledge, and practice during pregnancy and breastfeeding. The myths were examined individually, but for the purposes of statistical analysis, a score was obtained. We compared means of variables that could be associated to myth and knowledge scores, then calculated linear and logistical regressions. Forty-six percent of participants had below the mean myth scores. Ninety-two percent of participants had a knowledge score below the mean. Age (ß = 0.025, SE 0.007, 95% CI 0.011-0.040, p = 0.001) and years of education (ß = 0.166, SE 0.024, 95% CI 0.119-0.213, p = 0.001) explained the myth's score, while age explained the knowledge score (ß = 0.011, SE 0.020, 95% CI -0.032--0.008, p = 0.002). We found that although most women reported not believing in the myths, they acted on them. The probability of practicing such myths as "You must eat for two during pregnancy" was associated with being an adolescent (OR 1.76, p = 0.001) and being married (OR 1.47, p = 0.007), "Not satisfying cravings leave a mark on the infant's body" with being adolescent (OR 1.59, p = 0.003) and low socioeconomic level (OR 1.41, p = 0.038), "A frightened or angry mother should not nurse her baby" with being adult (OR 2.61, p = 0.004), and "Drinking atole or beer enhances breast milk production" with being single (OR 2.07, p = 0.001). The probability of not acting on some knowledge was associated with being an adolescent (p ≤ 0.003) and having a high school education or below (p ≤ 0.046). Almost all of our participants held at least one myth about nutrition and diet during pregnancy and breastfeeding; younger participants showed a higher frequency of holding myths. Years of schooling and age were associated with acting on myths and not acting on correct knowledge.


Assuntos
Fatores Etários , Dieta Saudável/psicologia , Escolaridade , Conhecimentos, Atitudes e Prática em Saúde , Gestantes/psicologia , Adolescente , Adulto , Aleitamento Materno/psicologia , Estudos Transversais , Feminino , Humanos , México , Gravidez
2.
Acta Gastroenterol Latinoam ; 46(2): 131-59, 2016 06.
Artigo em Espanhol | MEDLINE | ID: mdl-28704023

RESUMO

Obesity is an epidemic with important health repercussions in addition to high treatment-related costs. Between 2006 and 2007 the WHO developed new assessment tools, which aren't being globally used. In fact, there is no unified problem management across the hemisphere. Objectives: To update obesity epidemiology, to promote application of WHO's standards, to review new findings on physiopathology (i.e., fatty tissue as endocrine organ, intestinal microbiota), to update epidemiological information, and to provide management guidelines that can be integrated in clinical care. Methods: LAPSGHAN called up its members to collaborate in preparing this review article under the direction of an editor/coordinator, who selected the contents and literature with the best evidencetogether with the members. Each member prepared a separate document for each content. The chosen contents were later collated, unified, and edited. Results. This documents highlights the following: 1) Although extreme obesity is increasing in the US, overweight and obesity prevalence has stabilized, while in other countries it is alarmingly increasing; 2) New information regarding role of fatty tissue as endocrine organ and self-regulator of obesity; 3) The promising role of microbiota; and 4) Guidelines for children handling during consultation and follow-up. Conclusions: There is no widespread implementation of standards and guidelines from the World Health Organization (WHO). There is no agreement as to whether z-scores or percentiles should be used, especially regarding children under 2 due to their changing body complexion. The most accepted tool to assess overweight, obesity and severe obesity is the Body Mass Index (BMI). This document provides recommendations on how to approach clinical care with affected children.


Assuntos
Avaliação Nutricional , Obesidade , Tecido Adiposo/fisiologia , Criança , Microbioma Gastrointestinal , Humanos , América Latina/epidemiologia , Obesidade/diagnóstico , Obesidade/epidemiologia , Obesidade/etiologia , Obesidade/terapia , Sobrepeso/diagnóstico , Sobrepeso/epidemiologia , Sobrepeso/etiologia , Sobrepeso/terapia , Fatores de Risco , Sociedades Médicas , Organização Mundial da Saúde
3.
J Pediatr Gastroenterol Nutr ; 50(2): 123-31, 2010 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-20038846

RESUMO

The importance of hepatitis C viral infection in the health care of children has grown in recent decades. More is now known about the epidemiology of this infection in children and the progression of disease in the pediatric age group, and the treatment options are increasing. In this review, we update readers on the state of our understanding of hepatitis C infection in children, provide the current recommendations for monitoring and treatment, and discuss emerging therapies.


Assuntos
Antivirais/uso terapêutico , Hepatite C Crônica/tratamento farmacológico , Antivirais/efeitos adversos , Criança , Progressão da Doença , Hepacivirus/genética , Hepatite C Crônica/diagnóstico , Hepatite C Crônica/transmissão , Humanos , Lactente , Transmissão Vertical de Doenças Infecciosas
4.
J Pediatr Gastroenterol Nutr ; 49(2): 158-64, 2009 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-19561543

RESUMO

Autoimmune hepatitis is characterized by inflammatory liver histology, circulating nonorgan-specific autoantibodies, and increased levels of immunoglobulin G, in the absence of a known etiology. Two types of juvenile autoimmune hepatitis (AIH) are recognized according to seropositivity for smooth muscle and/or anti-nuclear antibody (AIH type 1) or liver kidney microsomal antibody (AIH type 2). There is a female predominance in both. AIH type 2 presents more acutely, at a younger age and commonly with immunoglobulin A deficiency, whereas duration of symptoms before diagnosis, clinical signs, family history of autoimmunity, presence of associated autoimmune disorders, response to treatment, and long-term prognosis are similar in the 2 groups. Immunosuppressive treatment with steroids and azathioprine, which should be instituted promptly to avoid progression to cirrhosis, induces remission in 80% of cases. Relapses are common, often due to nonadherence. Drugs effective in refractory cases include cyclosporine and mycophenolate mofetil. Long-term treatment is usually required, with only some 20% of AIH type 1 patients able to discontinue therapy successfully. In childhood, sclerosing cholangitis with strong autoimmune features, including interface hepatitis and serological features identical to AIH type 1, is as prevalent as AIH, but it affects boys and girls equally. Differential diagnosis relies on cholangiographic studies. In autoimmune sclerosing cholangitis liver parenchymal damage responds satisfactorily to immunosuppressive treatment, whereas bile duct disease tends to progress. In this article we review the state of the art of diagnosis, monitoring, and treatment for children with AIH.


Assuntos
Hepatite Autoimune , Imunossupressores/uso terapêutico , Adolescente , Criança , Feminino , Hepatite Autoimune/classificação , Hepatite Autoimune/diagnóstico , Hepatite Autoimune/terapia , Humanos , Transplante de Fígado , Masculino , Prednisolona/uso terapêutico
5.
J Pediatr Gastroenterol Nutr ; 48(4): 399-404, 2009 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-19322053

RESUMO

Hepatitis B virus (HBV) infection is a worldwide problem and can cause acute liver failure, acute hepatitis, chronic hepatitis, liver cirrhosis, and liver cancer. In areas of high prevalence such as in Asia, Africa, southern Europe, and Latin America, the hepatitis B surface antigen positive rate ranges from 2% to 20%.In endemic areas, HBV infection occurs mainly during infancy and early childhood. Mother-to-infant transmission accounts for approximately half of the chronic HBV infections. In contrast to infection in adults, HBV infection during early childhood results in a much higher rate of persistent infection and long-term serious complications such as liver cirrhosis and HCC.Three phases of chronic hepatitis B have been identified: the immune-tolerant phase, the immune-active phase, and the inactive hepatitis B phase. These phases of infection are characterized by variations in viral replication, hepatic inflammation, spontaneous clearance, and response to antiviral therapy.The optimal goal of antiviral therapy for chronic HBV infection is to eradicate HBV and to prevent its related liver complications. However, due to the limited effect of available therapies in viral eradication, the goal of treatment is to reduce viral replication, to minimize liver injury, and to reduce infectivity. In this review the current recommendations for monitoring and treating chronic HBV infection in children are reviewed.


Assuntos
Antivirais/uso terapêutico , Vírus da Hepatite B , Hepatite B Crônica/terapia , Pré-Escolar , Vírus da Hepatite B/imunologia , Hepatite B Crônica/sangue , Hepatite B Crônica/imunologia , Humanos , Lactente
6.
J Pediatr Gastroenterol Nutr ; 47 Suppl 1: S15-21, 2008 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-18667910

RESUMO

Glycogen storage diseases (GSDs) are a group of inherited disorders characterized by enzyme defects that affect the glycogen synthesis and degradation cycle, classified according to the enzyme deficiency and the affected tissue. The understanding of GSD has increased in recent decades, and nutritional management of some GSDs has allowed better control of hypoglycemia and metabolic complications. However, growth failure and liver, renal, and other complications are frequent problems in the long-term outcome. Hypoglycemia is the main biochemical consequence of GSD type I and some of the other GSDs. The basis of dietary therapy is nutritional manipulation to prevent hypoglycemia and improve metabolic dysfunction, with the use of continuous nocturnal intragastric feeding or cornstarch therapy at night and foods rich in starches with low concentrations of galactose and fructose during the day and to prevent hypoglycemia during the night.


Assuntos
Nutrição Enteral , Doença de Depósito de Glicogênio/dietoterapia , Glicogênio Sintase/deficiência , Fosforilase Quinase/deficiência , Criança , Pré-Escolar , Proteínas Alimentares/administração & dosagem , Proteínas Alimentares/uso terapêutico , Doença de Depósito de Glicogênio/classificação , Doença de Depósito de Glicogênio/terapia , Glicogênio Sintase/genética , Humanos , Hipoglicemia/prevenção & controle , Lactente , Recém-Nascido , Fosforilase Quinase/genética , Amido/administração & dosagem , Amido/uso terapêutico , Resultado do Tratamento
8.
Arch Med Res ; 38(6): 702-10, 2007 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-17613361

RESUMO

Hepatitis B and hepatitis C are important causes of chronic liver disease in children and adolescents, and later on for potential cirrhosis and primary hepatocellular carcinoma. The risk of developing chronic hepatitis B (HB) infection ranges from 90% in neonates to <5% in adults. Hepatitis C induces chronic infection in at least 85% of affected persons. HBV and HCV associated liver damage appears to be less severe in children than in adults. At the present time, lamivudine and a combination of interferon and lamivudine seem to be the best options for HB infection treatment in the pediatric population, even though they induce the presence of drug-resistant mutations, and new therapies have to be developed to improve reduction and cessation of viral replication and decrease the emergence of mutations. Therapy with interferon and ribavirin seems to offer the best results for children and adolescents. Results from a study on pegylated interferon in a pediatric population might lead to better therapeutic responses. Cost of treatment for chronic viral hepatitis is very high and efforts have to continue to extend hepatitis B vaccination to the general population worldwide to reduce vertical and horizontal transmission of hepatitis C.


Assuntos
Antivirais/uso terapêutico , Hepatite B Crônica/tratamento farmacológico , Hepatite C/tratamento farmacológico , Interferon-alfa/uso terapêutico , Adolescente , Criança , Pré-Escolar , Hepatite B Crônica/patologia , Hepatite B Crônica/prevenção & controle , Hepatite B Crônica/virologia , Hepatite C/patologia , Hepatite C/prevenção & controle , Hepatite C/virologia , Humanos , Imunização Passiva , Imunoglobulinas/uso terapêutico , Interferon-alfa/imunologia , Inibidores da Síntese de Ácido Nucleico/uso terapêutico
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