1.
Beilstein J Org Chem
; 13: 1816-1822, 2017.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28904625
RESUMO
Thiazolium carbene-catalyzed reactions of 1,2-diketones and 1,2,3-triketones with enones and ynones have been investigated. The diketones gave α,ß-double acylation products via unique Breslow intermediates isolable as acid salts, whereas the triketones formed stable adducts with the NHC instead of the coupling products.
2.
Chem Commun (Camb)
; 50(82): 12285-8, 2014 Oct 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25178473
RESUMO
Thiazolium carbene-catalyzed reaction of aromatic 1,2-diketones with enones in aprotic solvents gave double acylation products in good yields, whereas hydroacylation products formed by Stetter reaction were not detected at all. These results suggested the generation of aroyloxyenamine species from the 1,2-diketones instead of hydroxyenamines (Breslow intermediates).